{"id":"https://openalex.org/W1985458785","doi":"https://doi.org/10.1111/j.1538-7836.2006.01942.x","title":"Elevated levels of soluble fibrin or D\u2010dimer indicate high risk of thrombosis","display_name":"Elevated levels of soluble fibrin or D\u2010dimer indicate high risk of thrombosis","publication_year":2006,"publication_date":"2006-05-17","ids":{"openalex":"https://openalex.org/W1985458785","doi":"https://doi.org/10.1111/j.1538-7836.2006.01942.x","mag":"1985458785","pmid":"https://pubmed.ncbi.nlm.nih.gov/16706968"},"language":"en","primary_location":{"id":"doi:10.1111/j.1538-7836.2006.01942.x","doi":"https://doi.org/10.1111/j.1538-7836.2006.01942.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1538-7836.2006.01942.x","pdf_url":null,"source":{"id":"https://openalex.org/S164469042","display_name":"Journal of Thrombosis and Haemostasis","issn_l":"1538-7836","issn":["1538-7836","1538-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thrombosis and Haemostasis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1111/j.1538-7836.2006.01942.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101542693","display_name":"Hiroshi Wada","orcid":"https://orcid.org/0000-0002-7263-3232","observed_orcids":["https://orcid.org/0000-0002-7263-3232"]},"institutions":[{"id":"https://openalex.org/I178574317","display_name":"Mie University","ror":"https://ror.org/01529vy56","country_code":"JP","type":"education","lineage":["https://openalex.org/I178574317"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"H. WADA","raw_affiliation_strings":["Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Edobashi, Tsu, Japan. adahide@clin.medic.mie-u.ac.jp","Departments of Molecular and Laboratory Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Edobashi, Tsu, Japan. adahide@clin.medic.mie-u.ac.jp","institution_ids":["https://openalex.org/I178574317"]},{"raw_affiliation_string":"Departments of Molecular and Laboratory Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081750005","display_name":"Takashi Kobayashi","orcid":"https://orcid.org/0000-0001-7776-6846","observed_orcids":["https://orcid.org/0000-0001-7776-6846"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. KOBAYASHI","raw_affiliation_strings":["Hematology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037203151","display_name":"Yasunori Abe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y. ABE","raw_affiliation_strings":["Central Laboratory"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Laboratory","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071342355","display_name":"Tsuyoshi Hatada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. HATADA","raw_affiliation_strings":["Emergency Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emergency Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108107214","display_name":"Norikazu Yamada","orcid":"https://orcid.org/0009-0007-0166-8538","observed_orcids":["https://orcid.org/0009-0007-0166-8538"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. YAMADA","raw_affiliation_strings":["Cardiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042557807","display_name":"Akihiro Sudo","orcid":"https://orcid.org/0000-0003-0474-4368","observed_orcids":["https://orcid.org/0000-0003-0474-4368"]},"institutions":[{"id":"https://openalex.org/I178574317","display_name":"Mie University","ror":"https://ror.org/01529vy56","country_code":"JP","type":"education","lineage":["https://openalex.org/I178574317"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"A. SUDO","raw_affiliation_strings":["Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan","institution_ids":["https://openalex.org/I178574317"]}]},{"author_position":"middle","author":{"id":null,"display_name":"A. UCHIDA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I178574317","display_name":"Mie University","ror":"https://ror.org/01529vy56","country_code":"JP","type":"education","lineage":["https://openalex.org/I178574317"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"A. UCHIDA","raw_affiliation_strings":["Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan","institution_ids":["https://openalex.org/I178574317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007646392","display_name":"Tsutomu Nobori","orcid":"https://orcid.org/0000-0002-2632-6880","observed_orcids":["https://orcid.org/0000-0002-2632-6880"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. NOBORI","raw_affiliation_strings":["Departments of Molecular and Laboratory Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Molecular and Laboratory Medicine","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5101542693"],"corresponding_institution_ids":["https://openalex.org/I178574317"],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":7.3582,"has_fulltext":false,"cited_by_count":108,"citation_normalized_percentile":{"value":0.96663938,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"4","issue":"6","first_page":"1253","last_page":"1258"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.8109999895095825,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.8109999895095825,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.15060000121593475,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.03180000185966492,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/soluble-fibrin","display_name":"soluble fibrin","score":0.9919999837875366},{"id":"https://openalex.org/keywords/d-dimer","display_name":"D-dimer","score":1.0},{"id":"https://openalex.org/keywords/thrombosis-diagnosis","display_name":"thrombosis diagnosis","score":0.8939999938011169},{"id":"https://openalex.org/keywords/deep-vein-thrombosis","display_name":"deep vein thrombosis","score":0.9160000085830688},{"id":"https://openalex.org/keywords/disseminated-intravascular-coagulation","display_name":"disseminated intravascular coagulation","score":0.9879999756813049},{"id":"https://openalex.org/keywords/cerebral-thrombosis","display_name":"cerebral thrombosis","score":0.9369999766349792},{"id":"https://openalex.org/keywords/cutoff-values","display_name":"cut-off values","score":0.7979999780654907},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.5400000214576721},{"id":"https://openalex.org/keywords/liver-transplant-recipients","display_name":"liver transplant recipients","score":0.5789999961853027},{"id":"https://openalex.org/keywords/postoperative-patients","display_name":"postoperative patients","score":0.9559999704360962}],"concepts":[{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.8712109327316284},{"id":"https://openalex.org/C2779519742","wikidata":"https://www.wikidata.org/wiki/Q198526","display_name":"D-dimer","level":2,"score":0.8674927949905396},{"id":"https://openalex.org/C54173615","wikidata":"https://www.wikidata.org/wiki/Q27205","display_name":"Fibrin","level":2,"score":0.7412006855010986},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7266169786453247},{"id":"https://openalex.org/C2778959117","wikidata":"https://www.wikidata.org/wiki/Q430892","display_name":"Deep vein","level":3,"score":0.5685065984725952},{"id":"https://openalex.org/C2778382381","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Coagulation","level":2,"score":0.47044745087623596},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4611653685569763},{"id":"https://openalex.org/C2780011451","wikidata":"https://www.wikidata.org/wiki/Q2751330","display_name":"Venous thrombosis","level":3,"score":0.4489096403121948},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.44353264570236206},{"id":"https://openalex.org/C2778734968","wikidata":"https://www.wikidata.org/wiki/Q823027","display_name":"Disseminated intravascular coagulation","level":2,"score":0.42554277181625366},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.34248971939086914},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.20344111323356628}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001847","descriptor_name":"Bone Diseases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001847","descriptor_name":"Bone Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003141","descriptor_name":"Communicable Diseases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003141","descriptor_name":"Communicable Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D004211","descriptor_name":"Disseminated Intravascular Coagulation","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D004211","descriptor_name":"Disseminated Intravascular Coagulation","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D004211","descriptor_name":"Disseminated Intravascular Coagulation","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005337","descriptor_name":"Fibrin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005338","descriptor_name":"Fibrin Fibrinogen Degradation Products","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D020246","descriptor_name":"Venous Thrombosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020246","descriptor_name":"Venous Thrombosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D020767","descriptor_name":"Intracranial Thrombosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D020767","descriptor_name":"Intracranial Thrombosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1538-7836.2006.01942.x","doi":"https://doi.org/10.1111/j.1538-7836.2006.01942.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1538-7836.2006.01942.x","pdf_url":null,"source":{"id":"https://openalex.org/S164469042","display_name":"Journal of Thrombosis and Haemostasis","issn_l":"1538-7836","issn":["1538-7836","1538-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thrombosis and Haemostasis","raw_type":"journal-article"},{"id":"pmid:16706968","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16706968","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of thrombosis and haemostasis : JTH","raw_type":"Evaluation Study"}],"best_oa_location":{"id":"doi:10.1111/j.1538-7836.2006.01942.x","doi":"https://doi.org/10.1111/j.1538-7836.2006.01942.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1538-7836.2006.01942.x","pdf_url":null,"source":{"id":"https://openalex.org/S164469042","display_name":"Journal of Thrombosis and Haemostasis","issn_l":"1538-7836","issn":["1538-7836","1538-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thrombosis and Haemostasis","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W335124151","https://openalex.org/W1862054033","https://openalex.org/W1964839436","https://openalex.org/W1976113730","https://openalex.org/W2019848266","https://openalex.org/W2031038818","https://openalex.org/W2031202586","https://openalex.org/W2037754467","https://openalex.org/W2053261976","https://openalex.org/W2059437234","https://openalex.org/W2064553209","https://openalex.org/W2064682186","https://openalex.org/W2070237559","https://openalex.org/W2073688259","https://openalex.org/W2077314757","https://openalex.org/W2078842586","https://openalex.org/W2081208976","https://openalex.org/W2085346107","https://openalex.org/W2091528299","https://openalex.org/W2164509627","https://openalex.org/W2167728254","https://openalex.org/W2170425397","https://openalex.org/W2254264285","https://openalex.org/W2331697328","https://openalex.org/W2415217764","https://openalex.org/W2468481754","https://openalex.org/W3176259842","https://openalex.org/W4232778821","https://openalex.org/W4292994461","https://openalex.org/W4297171911","https://openalex.org/W4365787275","https://openalex.org/W4378211146","https://openalex.org/W6797534184"],"related_works":["https://openalex.org/W4361275497","https://openalex.org/W2044336004","https://openalex.org/W2070237559","https://openalex.org/W2022424611","https://openalex.org/W2069742786","https://openalex.org/W2063025783","https://openalex.org/W1982604681","https://openalex.org/W3028679841","https://openalex.org/W2081208976","https://openalex.org/W2098282767"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}