{"id":"https://openalex.org/W1985408696","doi":"https://doi.org/10.1093/jac/11.suppl_b.169","title":"A comparison of azlocillin and gentamicin in the treatment of serious infections caused by Pseudomonas aeruginosa","display_name":"A comparison of azlocillin and gentamicin in the treatment of serious infections caused by Pseudomonas aeruginosa","publication_year":1983,"publication_date":"1983-01-01","ids":{"openalex":"https://openalex.org/W1985408696","doi":"https://doi.org/10.1093/jac/11.suppl_b.169","mag":"1985408696","pmid":"https://pubmed.ncbi.nlm.nih.gov/6352600"},"language":"en","primary_location":{"id":"doi:10.1093/jac/11.suppl_b.169","doi":"https://doi.org/10.1093/jac/11.suppl_b.169","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jac/11.suppl_b.169","pdf_url":null,"source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009308999","display_name":"Miranda Gonz\u00e1lez","orcid":"https://orcid.org/0000-0002-9193-177X","observed_orcids":["https://orcid.org/0000-0002-9193-177X"]},"institutions":[{"id":"https://openalex.org/I2802421035","display_name":"Hospital General de M\u00e9xico","ror":"https://ror.org/01php1d31","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I2802421035","https://openalex.org/I4210095685"]},{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"M. A. Gonzalez","raw_affiliation_strings":["National Autonomous University of Mexico, Hospital General de Mexico Mexico City, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Autonomous University of Mexico, Hospital General de Mexico Mexico City, Mexico","institution_ids":["https://openalex.org/I2802421035","https://openalex.org/I8961855"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5009308999"],"corresponding_institution_ids":["https://openalex.org/I2802421035","https://openalex.org/I8961855"],"apc_list":{"value":2869,"currency":"GBP","value_usd":3784},"apc_paid":null,"fwci":0.3408,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.54368733,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":"suppl B","first_page":"169","last_page":"174"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.023800000548362732,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.019899999722838402,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/azlocillin","display_name":"azlocillin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/gentamicin","display_name":"gentamicin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":0.9819999933242798},{"id":"https://openalex.org/keywords/severe-infection","display_name":"serious infections","score":0.7390000224113464},{"id":"https://openalex.org/keywords/skin-and-skin-structure-infections","display_name":"skin and skin structure infections","score":0.7789999842643738},{"id":"https://openalex.org/keywords/lower-respiratory-tract-infection","display_name":"lower respiratory tract infection","score":0.9959999918937683},{"id":"https://openalex.org/keywords/beta-lactam-antibiotics","display_name":"beta-lactam antibiotics","score":0.796999990940094},{"id":"https://openalex.org/keywords/aminoglycosides","display_name":"aminoglycosides","score":0.9150000214576721},{"id":"https://openalex.org/keywords/antibiotic-efficacy","display_name":"antibiotic efficacy","score":0.609000027179718},{"id":"https://openalex.org/keywords/antibiotic-safety","display_name":"antibiotic safety","score":0.5720000267028809},{"id":"https://openalex.org/keywords/bacterial-killing","display_name":"bacterial killing","score":0.5899999737739563}],"concepts":[{"id":"https://openalex.org/C2776182393","wikidata":"https://www.wikidata.org/wiki/Q510154","display_name":"Azlocillin","level":5,"score":0.9883664846420288},{"id":"https://openalex.org/C2775832221","wikidata":"https://www.wikidata.org/wiki/Q422482","display_name":"Gentamicin","level":3,"score":0.8800710439682007},{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.7551689743995667},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5542254447937012},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5505686402320862},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5217210054397583},{"id":"https://openalex.org/C2779644171","wikidata":"https://www.wikidata.org/wiki/Q13400765","display_name":"Respiratory tract","level":3,"score":0.49566686153411865},{"id":"https://openalex.org/C2776012195","wikidata":"https://www.wikidata.org/wiki/Q754447","display_name":"Respiratory tract infections","level":3,"score":0.47473010420799255},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3232252895832062},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2891572117805481},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.25145217776298523},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.238337904214859},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.17840030789375305},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C2778193466","wikidata":"https://www.wikidata.org/wiki/Q423787","display_name":"Piperacillin","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001390","descriptor_name":"Azlocillin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005839","descriptor_name":"Gentamicins","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005839","descriptor_name":"Gentamicins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010406","descriptor_name":"Penicillins","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D010406","descriptor_name":"Penicillins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/jac/11.suppl_b.169","doi":"https://doi.org/10.1093/jac/11.suppl_b.169","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jac/11.suppl_b.169","pdf_url":null,"source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},{"id":"pmid:6352600","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6352600","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of antimicrobial chemotherapy","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2053534474","https://openalex.org/W2164708732","https://openalex.org/W2324862415","https://openalex.org/W7097790422","https://openalex.org/W1993212159","https://openalex.org/W156532177","https://openalex.org/W2401118085","https://openalex.org/W2404880869","https://openalex.org/W2323777222","https://openalex.org/W2057983371"],"abstract_inverted_index":{"A":[0],"randomized":[1],"controlled":[2],"clinical":[3,80,115],"trial":[4],"to":[5],"compare":[6],"the":[7,25,41,46,52,57,87,93,99,120,127],"efficacy":[8],"and":[9,13,30,49,89,122],"safety":[10],"of":[11,24,40,56,68,71,86,92,103,109,119,124,126],"azlocillin":[12,47,74],"gentamicin":[14,53,100],"was":[15,36,82],"conducted":[16],"in":[17,45,51,84,117],"42":[18],"patients":[19],"with":[20,73],"serious":[21],"infections,":[22],"primarily":[23],"skin":[26,28],"or":[27],"structure":[29],"lower":[31],"respiratory":[32],"tract.":[33],"Pseudomonas":[34],"aeruginosa":[35],"isolated":[37],"from":[38],"each":[39],"25":[42],"infection":[43],"sites":[44,58],"group":[48],"18":[50,76],"group;":[54],"most":[55],"were":[59,96],"also":[60],"infected":[61],"by":[62],"other":[63],"pathogens.":[64,129],"After":[65],"a":[66,78,107,113],"mean":[67,108],"13":[69],"days":[70,111],"treatment":[72],"at":[75],"g/day,":[77],"good":[79,114],"response":[81,116],"attained":[83],"96%":[85],"cases,":[88,121],"nearly":[90],"90%":[91],"causative":[94,128],"organisms":[95],"eradicated.":[97],"In":[98],"group,":[101],"administration":[102],"180":[104],"mg/day":[105],"for":[106],"11":[110],"provided":[112],"95%":[118],"eradication":[123],"92%":[125]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}