{"id":"https://openalex.org/W1985407591","doi":"https://doi.org/10.1016/s0306-4530(00)00050-0","title":"Hypothalamic pituitary gonadal axis dysregulation in depressed women","display_name":"Hypothalamic pituitary gonadal axis dysregulation in depressed women","publication_year":2001,"publication_date":"2001-04-01","ids":{"openalex":"https://openalex.org/W1985407591","doi":"https://doi.org/10.1016/s0306-4530(00)00050-0","mag":"1985407591","pmid":"https://pubmed.ncbi.nlm.nih.gov/11166488"},"language":"en","primary_location":{"id":"doi:10.1016/s0306-4530(00)00050-0","doi":"https://doi.org/10.1016/s0306-4530(00)00050-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0306-4530(00)00050-0","pdf_url":null,"source":{"id":"https://openalex.org/S81924583","display_name":"Psychoneuroendocrinology","issn_l":"0306-4530","issn":["0306-4530","1873-3360"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychoneuroendocrinology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039532561","display_name":"William H. Meller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1309104334","display_name":"Fairview Health Services","ror":"https://ror.org/04hsn8391","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1309104334"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"William H. Meller","raw_affiliation_strings":["Department of Psychiatry, Fairview-University Medical Center, Minneapolis, MN 55455, USA","Department of Psychiatry, Fairview-University Medical Center, 2450 Riverside Avenue, Minneapolis, MN 55455, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Fairview-University Medical Center, Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I1309104334"]},{"raw_affiliation_string":"Department of Psychiatry, Fairview-University Medical Center, 2450 Riverside Avenue, Minneapolis, MN 55455, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111774816","display_name":"Patricia L. Grambsch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia L. Grambsch","raw_affiliation_strings":["Department of Biostatistics, Box 303 Mayo, 420 Delaware Street, University of Minnesota, Minneapolis, MN 55455, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Box 303 Mayo, 420 Delaware Street, University of Minnesota, Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111368699","display_name":"C. Raymond Bingham","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher Bingham","raw_affiliation_strings":["School of Statistics, 233 Ford Hall, 225 Church Street SE, University of Minnesota, Minneapolis, MN 55455, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Statistics, 233 Ford Hall, 225 Church Street SE, University of Minnesota, Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065706574","display_name":"George E. Tagatz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George E. Tagatz","raw_affiliation_strings":["Department of Gynecology, Box 395 Mayo, 420 Delaware Street, University of Minnesota, Minneapolis, MN 55455, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, Box 395 Mayo, 420 Delaware Street, University of Minnesota, Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5039532561"],"corresponding_institution_ids":["https://openalex.org/I1309104334"],"apc_list":{"value":3830,"currency":"USD","value_usd":3830},"apc_paid":null,"fwci":2.5654,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.86783439,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"26","issue":"3","first_page":"253","last_page":"259"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.8467000126838684,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.8467000126838684,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.1476999968290329,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypothalamic-pituitary-gonadal-axis","display_name":"hypothalamic-pituitary-gonadal axis","score":0.9480000138282776},{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":0.9269999861717224},{"id":"https://openalex.org/keywords/luteinizing-hormone","display_name":"luteinizing hormone","score":0.8669999837875366},{"id":"https://openalex.org/keywords/lh-pulsatility","display_name":"LH pulsatility","score":0.9779999852180481},{"id":"https://openalex.org/keywords/menstrual-cycle","display_name":"menstrual cycle","score":0.8389999866485596},{"id":"https://openalex.org/keywords/women","display_name":"women","score":0.5770000219345093},{"id":"https://openalex.org/keywords/clustering","display_name":"clustering","score":0.47999998927116394},{"id":"https://openalex.org/keywords/spectral-analysis","display_name":"spectral analysis","score":0.9729999899864197}],"concepts":[{"id":"https://openalex.org/C2778575703","wikidata":"https://www.wikidata.org/wiki/Q50265477","display_name":"Luteinizing hormone","level":3,"score":0.7624138593673706},{"id":"https://openalex.org/C79191276","wikidata":"https://www.wikidata.org/wiki/Q7259620","display_name":"Pulsatile flow","level":2,"score":0.7571762800216675},{"id":"https://openalex.org/C2779058012","wikidata":"https://www.wikidata.org/wiki/Q83864","display_name":"Menstrual cycle","level":3,"score":0.6519927978515625},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5894359946250916},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5860314965248108},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5711178183555603},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5544843673706055},{"id":"https://openalex.org/C146819174","wikidata":"https://www.wikidata.org/wiki/Q1703595","display_name":"Hypothalamic\u2013pituitary\u2013gonadal axis","level":4,"score":0.4478345215320587},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40661460161209106},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.39592722058296204},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.32079824805259705},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007030","descriptor_name":"Hypothalamo-Hypophyseal System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D007986","descriptor_name":"Luteinizing Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D010053","descriptor_name":"Ovary","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D010507","descriptor_name":"Periodicity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0306-4530(00)00050-0","doi":"https://doi.org/10.1016/s0306-4530(00)00050-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0306-4530(00)00050-0","pdf_url":null,"source":{"id":"https://openalex.org/S81924583","display_name":"Psychoneuroendocrinology","issn_l":"0306-4530","issn":["0306-4530","1873-3360"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychoneuroendocrinology","raw_type":"journal-article"},{"id":"pmid:11166488","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11166488","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychoneuroendocrinology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G231033738","display_name":"GCRC-General Clinical Research Center","funder_award_id":"M01RR000400","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G375278287","display_name":"TEACHING AND RESEARCH IN DEPRESSION","funder_award_id":"1t01mh019815-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G472163302","display_name":"LUTEINIZING HORMONE PULSE CHARACTERISTICS IN DEPRESSION","funder_award_id":"R03MH052287","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6707487173","display_name":null,"funder_award_id":"T01 MH 19815-01","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W154588542","https://openalex.org/W227078082","https://openalex.org/W598926496","https://openalex.org/W1628674998","https://openalex.org/W1803314860","https://openalex.org/W1880023255","https://openalex.org/W1988947995","https://openalex.org/W2004827099","https://openalex.org/W2036811914","https://openalex.org/W2050006242","https://openalex.org/W2071599591","https://openalex.org/W2073748258","https://openalex.org/W2075396083","https://openalex.org/W2080243633","https://openalex.org/W2085461121","https://openalex.org/W2159011576","https://openalex.org/W2161627101","https://openalex.org/W2314956455","https://openalex.org/W2326465498","https://openalex.org/W2327397899","https://openalex.org/W2414144786","https://openalex.org/W2911887375","https://openalex.org/W3013430759","https://openalex.org/W4210957923"],"related_works":["https://openalex.org/W1628674998","https://openalex.org/W7096538755","https://openalex.org/W1984891073","https://openalex.org/W1995646441","https://openalex.org/W2142075748","https://openalex.org/W1977089656","https://openalex.org/W1999141796","https://openalex.org/W2037372036","https://openalex.org/W2984075515","https://openalex.org/W2037753553"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}