{"id":"https://openalex.org/W1985374393","doi":"https://doi.org/10.1007/bf02256069","title":"The Effect of C-Terminal Mutations of HSP60 on Protein Folding","display_name":"The Effect of C-Terminal Mutations of HSP60 on Protein Folding","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W1985374393","doi":"https://doi.org/10.1007/bf02256069","mag":"1985374393","pmid":"https://pubmed.ncbi.nlm.nih.gov/12065897"},"language":"en","primary_location":{"id":"doi:10.1007/bf02256069","doi":"https://doi.org/10.1007/bf02256069","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02256069","pdf_url":null,"source":{"id":"https://openalex.org/S52607827","display_name":"Journal of Biomedical Science","issn_l":"1021-7770","issn":["1021-7770","1423-0127"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109187776","display_name":"Yi\u2010Chien Fang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yi-Chien Fang","raw_affiliation_strings":["Institute of Genetics, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I4387156312"]}]},{"author_position":"last","author":{"id":null,"display_name":"Mingyuan Cheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387156312","display_name":"National Yang Ming University","ror":"https://ror.org/009h5ks85","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613","https://openalex.org/I4387156312"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Mingyuan Cheng","raw_affiliation_strings":["Institute of Genetics, School of Life Sciences, National Yang-Ming University, 155 Li-nung Street Sec. 2 Shih-Pai, 112, Taipei, Taiwan (ROC)","Institute of Genetics, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics, School of Life Sciences, National Yang-Ming University, 155 Li-nung Street Sec. 2 Shih-Pai, 112, Taipei, Taiwan (ROC)","institution_ids":["https://openalex.org/I4387156312"]},{"raw_affiliation_string":"Institute of Genetics, School of Life Sciences, National Yang-Ming University, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I4387156312"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4387156312"],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.0956,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.36459157,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"9","issue":"3","first_page":"223","last_page":"233"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hsp60","display_name":"HSP60","score":0.9739999771118164},{"id":"https://openalex.org/keywords/c-terminal-mutations","display_name":"C-terminal mutations","score":0.7519999742507935},{"id":"https://openalex.org/keywords/protein-folding","display_name":"protein folding","score":0.9010000228881836},{"id":"https://openalex.org/keywords/chaperonin","display_name":"chaperonin","score":0.7210000157356262},{"id":"https://openalex.org/keywords/hsp10","display_name":"Hsp10","score":0.7170000076293945},{"id":"https://openalex.org/keywords/non-fermentable-carbon-sources","display_name":"non-fermentable carbon sources","score":0.7059999704360962},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.8820000290870667}],"concepts":[{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.7384394407272339},{"id":"https://openalex.org/C146621620","wikidata":"https://www.wikidata.org/wiki/Q24771589","display_name":"HSP60","level":5,"score":0.6757292747497559},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.5691180229187012},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.5567726492881775},{"id":"https://openalex.org/C2779033446","wikidata":"https://www.wikidata.org/wiki/Q423139","display_name":"Rhodanese","level":3,"score":0.5419403910636902},{"id":"https://openalex.org/C87190427","wikidata":"https://www.wikidata.org/wiki/Q14864994","display_name":"GroEL","level":4,"score":0.5402611494064331},{"id":"https://openalex.org/C204328495","wikidata":"https://www.wikidata.org/wiki/Q847556","display_name":"Protein folding","level":2,"score":0.5369932651519775},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5233746767044067},{"id":"https://openalex.org/C85755625","wikidata":"https://www.wikidata.org/wiki/Q24771589","display_name":"Chaperonin","level":3,"score":0.5138474106788635},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.49649912118911743},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.461737722158432},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.44485774636268616},{"id":"https://openalex.org/C205260736","wikidata":"https://www.wikidata.org/wiki/Q418939","display_name":"Heat shock protein","level":3,"score":0.354569673538208},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.35407376289367676},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.31926625967025757},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.2931002974510193},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.223921537399292},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.10754743218421936},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.09189632534980774},{"id":"https://openalex.org/C68991219","wikidata":"https://www.wikidata.org/wiki/Q419102","display_name":"Hsp70","level":4,"score":0.08451488614082336}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011489","descriptor_name":"Protein Denaturation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013884","descriptor_name":"Thiosulfate Sulfurtransferase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013884","descriptor_name":"Thiosulfate Sulfurtransferase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016297","descriptor_name":"Mutagenesis, Site-Directed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018834","descriptor_name":"Chaperonin 60","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018834","descriptor_name":"Chaperonin 60","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018834","descriptor_name":"Chaperonin 60","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018835","descriptor_name":"Chaperonin 10","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018835","descriptor_name":"Chaperonin 10","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018835","descriptor_name":"Chaperonin 10","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D046911","descriptor_name":"Macromolecular Substances","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/bf02256069","doi":"https://doi.org/10.1007/bf02256069","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02256069","pdf_url":null,"source":{"id":"https://openalex.org/S52607827","display_name":"Journal of Biomedical Science","issn_l":"1021-7770","issn":["1021-7770","1423-0127"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Science","raw_type":"journal-article"},{"id":"doi:10.1159/000059423","doi":"https://doi.org/10.1159/000059423","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000059423","pdf_url":null,"source":{"id":"https://openalex.org/S52607827","display_name":"Journal of Biomedical Science","issn_l":"1021-7770","issn":["1021-7770","1423-0127"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Science","raw_type":"journal-article"},{"id":"pmid:12065897","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12065897","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomedical science","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321040","display_name":"National Science Council","ror":"https://ror.org/02kv4zf79"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W134641183","https://openalex.org/W1159560137","https://openalex.org/W1533808701","https://openalex.org/W1559420025","https://openalex.org/W1594700207","https://openalex.org/W1772457329","https://openalex.org/W1892996896","https://openalex.org/W1963770237","https://openalex.org/W1965255559","https://openalex.org/W1971227091","https://openalex.org/W1980627844","https://openalex.org/W2009324686","https://openalex.org/W2010216870","https://openalex.org/W2017886114","https://openalex.org/W2022796050","https://openalex.org/W2026640271","https://openalex.org/W2033172386","https://openalex.org/W2036931150","https://openalex.org/W2039486080","https://openalex.org/W2040164455","https://openalex.org/W2042745916","https://openalex.org/W2042930193","https://openalex.org/W2048076616","https://openalex.org/W2052357124","https://openalex.org/W2065362324","https://openalex.org/W2077647616","https://openalex.org/W2081422975","https://openalex.org/W2081600094","https://openalex.org/W2088647375","https://openalex.org/W2088981849","https://openalex.org/W2091183731","https://openalex.org/W2099421513","https://openalex.org/W2099757932","https://openalex.org/W2119999468","https://openalex.org/W2134502101","https://openalex.org/W2142338805","https://openalex.org/W2157063391","https://openalex.org/W2157751905","https://openalex.org/W2255981737","https://openalex.org/W2412288399","https://openalex.org/W4206302388","https://openalex.org/W6991471613"],"related_works":["https://openalex.org/W7095834413","https://openalex.org/W2081600094","https://openalex.org/W4386804390","https://openalex.org/W7015760397","https://openalex.org/W2031696618","https://openalex.org/W2770664255","https://openalex.org/W2062775685","https://openalex.org/W4402422454","https://openalex.org/W2048076616","https://openalex.org/W1999928896"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":4},{"year":2020,"cited_by_count":3}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}