{"id":"https://openalex.org/W198533119","doi":"https://doi.org/10.1055/s-2004-815668","title":"Airway Clearance Techniques","display_name":"Airway Clearance Techniques","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W198533119","doi":"https://doi.org/10.1055/s-2004-815668","mag":"198533119","pmid":"https://pubmed.ncbi.nlm.nih.gov/16088588"},"language":"en","primary_location":{"id":"doi:10.1055/s-2004-815668","doi":"https://doi.org/10.1055/s-2004-815668","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2004-815668","pdf_url":null,"source":{"id":"https://openalex.org/S193428046","display_name":"Seminars in Respiratory and Critical Care Medicine","issn_l":"1069-3424","issn":["1069-3424","1098-9048"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Respiratory and Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005915390","display_name":"Patrick A. Flume","orcid":"https://orcid.org/0000-0002-1560-6879","observed_orcids":["https://orcid.org/0000-0002-1560-6879"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Patrick A. Flume","raw_affiliation_strings":["Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina 29425, USA. flumepa@musc.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina 29425, USA. flumepa@musc.edu","institution_ids":["https://openalex.org/I153297377"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5005915390"],"corresponding_institution_ids":["https://openalex.org/I153297377"],"apc_list":null,"apc_paid":null,"fwci":0.258,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.59736153,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"24","issue":"6","first_page":"727","last_page":"736"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12418","display_name":"Respiratory and Cough-Related Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/airway-clearance","display_name":"airway clearance","score":0.8159999847412109},{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/mucociliary-clearance","display_name":"mucociliary clearance","score":0.8399999737739563},{"id":"https://openalex.org/keywords/airway-mucus","display_name":"airway mucus","score":0.7599999904632568},{"id":"https://openalex.org/keywords/sputum-clearance","display_name":"sputum clearance","score":0.6790000200271606},{"id":"https://openalex.org/keywords/airway-clearance-techniques","display_name":"airway clearance techniques","score":0.6589999794960022},{"id":"https://openalex.org/keywords/chronic-airway-infection","display_name":"chronic airway infection","score":0.6510000228881836}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9615342617034912},{"id":"https://openalex.org/C114682108","wikidata":"https://www.wikidata.org/wiki/Q1952044","display_name":"Mucociliary clearance","level":3,"score":0.9330844879150391},{"id":"https://openalex.org/C2776938444","wikidata":"https://www.wikidata.org/wiki/Q178194","display_name":"Cystic fibrosis","level":2,"score":0.9019882678985596},{"id":"https://openalex.org/C2776301714","wikidata":"https://www.wikidata.org/wiki/Q259346","display_name":"Sputum","level":3,"score":0.8204195499420166},{"id":"https://openalex.org/C2777312293","wikidata":"https://www.wikidata.org/wiki/Q3649349","display_name":"Mucus","level":2,"score":0.8054391741752625},{"id":"https://openalex.org/C105922876","wikidata":"https://www.wikidata.org/wiki/Q1423981","display_name":"Airway","level":2,"score":0.7404323220252991},{"id":"https://openalex.org/C2776705957","wikidata":"https://www.wikidata.org/wiki/Q3099854","display_name":"Chest physiotherapy","level":2,"score":0.4636956453323364},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.44669294357299805},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.33270537853240967},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2928932309150696},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.2553500235080719},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2075406312942505},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.19367924332618713},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.07038876414299011},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1055/s-2004-815668","doi":"https://doi.org/10.1055/s-2004-815668","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2004-815668","pdf_url":null,"source":{"id":"https://openalex.org/S193428046","display_name":"Seminars in Respiratory and Critical Care Medicine","issn_l":"1069-3424","issn":["1069-3424","1098-9048"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Respiratory and Critical Care Medicine","raw_type":"journal-article"},{"id":"pmid:16088588","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16088588","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in respiratory and critical care medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7096651593","https://openalex.org/W2100641922","https://openalex.org/W75474265","https://openalex.org/W3169356024","https://openalex.org/W4365136023","https://openalex.org/W2416529934","https://openalex.org/W4361836214","https://openalex.org/W4220698915","https://openalex.org/W2061339198","https://openalex.org/W2033931164"],"abstract_inverted_index":{"The":[0],"airways":[1,18,53],"of":[2,21,54,77,111],"the":[3,17,22,25,55,61,75,78,82,95,105,109],"patient":[4,119],"with":[5,39],"cystic":[6],"fibrosis":[7],"(CF)":[8],"are":[9],"chronically":[10],"infected.":[11],"There":[12],"is":[13,35],"excess":[14,79],"mucus":[15,26],"within":[16],"and,":[19],"because":[20],"chronic":[23],"infection,":[24],"also":[27],"contains":[28],"bacteria":[29],"and":[30,41,47,64,97],"inflammatory":[31],"cells.":[32],"Mucociliary":[33],"clearance":[34,76,113],"impaired":[36],"in":[37,81],"patients":[38,42,100],"CF,":[40],"become":[43],"dependent":[44],"upon":[45],"cough":[46],"other":[48],"techniques":[49,63],"to":[50,70,91,120],"clear":[51],"their":[52],"thick":[56],"sputum.":[57],"This":[58],"review":[59],"discusses":[60],"various":[62],"medications":[65],"that":[66],"have":[67],"been":[68,89],"demonstrated":[69],"be":[71,92,115],"effective":[72,122],"at":[73],"assisting":[74],"secretions":[80],"CF":[83],"airways.":[84],"No":[85],"single":[86],"method":[87],"has":[88],"proven":[90],"better":[93],"than":[94],"others,":[96],"not":[98],"all":[99],"will":[101],"benefit,":[102],"or":[103],"use,":[104],"same":[106],"techniques.":[107],"Therefore,":[108],"methods":[110],"airway":[112],"must":[114],"tailored":[116],"for":[117],"each":[118],"assure":[121],"therapy.":[123]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}