{"id":"https://openalex.org/W1985204716","doi":"https://doi.org/10.1136/jcp.34.4.381","title":"Plasma cell counts on human jejunal biopsy specimens examined by immunofluorescence and immunoperoxidase techniques: a comparative study.","display_name":"Plasma cell counts on human jejunal biopsy specimens examined by immunofluorescence and immunoperoxidase techniques: a comparative study.","publication_year":1981,"publication_date":"1981-04-01","ids":{"openalex":"https://openalex.org/W1985204716","doi":"https://doi.org/10.1136/jcp.34.4.381","mag":"1985204716","pmid":"https://pubmed.ncbi.nlm.nih.gov/7016923","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/493295"},"language":"en","primary_location":{"id":"doi:10.1136/jcp.34.4.381","doi":"https://doi.org/10.1136/jcp.34.4.381","is_oa":true,"landing_page_url":"https://doi.org/10.1136/jcp.34.4.381","pdf_url":"https://jcp.bmj.com/content/jclinpath/34/4/381.full.pdf","source":{"id":"https://openalex.org/S37362813","display_name":"Journal of Clinical Pathology","issn_l":"0021-9746","issn":["0021-9746","1472-4146"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://jcp.bmj.com/content/jclinpath/34/4/381.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"D Kingston","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Kingston","raw_affiliation_strings":["From the Intestinal Studies Group, Division of Clinicol Sciences, Clinical Research Centre, Watford Road, Harrow, Middx HA 1 3UJ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Intestinal Studies Group, Division of Clinicol Sciences, Clinical Research Centre, Watford Road, Harrow, Middx HA 1 3UJ, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"J R Pearson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J R Pearson","raw_affiliation_strings":["From the Intestinal Studies Group, Division of Clinicol Sciences, Clinical Research Centre, Watford Road, Harrow, Middx HA 1 3UJ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Intestinal Studies Group, Division of Clinicol Sciences, Clinical Research Centre, Watford Road, Harrow, Middx HA 1 3UJ, UK","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081247604","display_name":"Francisco Jos\u00e9 Penna","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F J Penna","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.8463,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.82718727,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"34","issue":"4","first_page":"381","last_page":"385"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11348","display_name":"Celiac Disease Research and Management","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11348","display_name":"Celiac Disease Research and Management","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.007000000216066837,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13199","display_name":"Digestive system and related health","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/jejunal-biopsy","display_name":"jejunal biopsy","score":0.9520000219345093},{"id":"https://openalex.org/keywords/immunofluorescence","display_name":"immunofluorescence","score":0.9200000166893005},{"id":"https://openalex.org/keywords/immunoperoxidase-staining","display_name":"immunoperoxidase staining","score":0.9419999718666077},{"id":"https://openalex.org/keywords/iga","display_name":"IgA","score":0.9139999747276306},{"id":"https://openalex.org/keywords/igm","display_name":"IgM","score":0.9990000128746033},{"id":"https://openalex.org/keywords/villous-atrophy","display_name":"villous atrophy","score":0.9200000166893005},{"id":"https://openalex.org/keywords/small-intestine","display_name":"small intestine","score":0.5410000085830688},{"id":"https://openalex.org/keywords/staining-technique-comparison","display_name":"staining technique comparison","score":0.4659999907016754}],"concepts":[{"id":"https://openalex.org/C128102431","wikidata":"https://www.wikidata.org/wiki/Q6005550","display_name":"Immunoperoxidase","level":4,"score":0.8632827997207642},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.6968543529510498},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.6194809675216675},{"id":"https://openalex.org/C2778236600","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Immunofluorescence","level":3,"score":0.609832763671875},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.5704598426818848},{"id":"https://openalex.org/C74864618","wikidata":"https://www.wikidata.org/wiki/Q2332446","display_name":"Staining","level":2,"score":0.5611023306846619},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5147876739501953},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48003947734832764},{"id":"https://openalex.org/C2776396001","wikidata":"https://www.wikidata.org/wiki/Q250694","display_name":"Plasma cell","level":3,"score":0.4526016116142273},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3003937602043152},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2331324815750122},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.10628482699394226},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08562058210372925}],"mesh":[{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007070","descriptor_name":"Immunoglobulin A","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007075","descriptor_name":"Immunoglobulin M","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007583","descriptor_name":"Jejunum","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D007583","descriptor_name":"Jejunum","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010950","descriptor_name":"Plasma Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1136/jcp.34.4.381","doi":"https://doi.org/10.1136/jcp.34.4.381","is_oa":true,"landing_page_url":"https://doi.org/10.1136/jcp.34.4.381","pdf_url":"https://jcp.bmj.com/content/jclinpath/34/4/381.full.pdf","source":{"id":"https://openalex.org/S37362813","display_name":"Journal of Clinical Pathology","issn_l":"0021-9746","issn":["0021-9746","1472-4146"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Pathology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:493295","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/493295","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Pathol","raw_type":"Text"},{"id":"pmid:7016923","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7016923","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical pathology","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1136/jcp.34.4.381","doi":"https://doi.org/10.1136/jcp.34.4.381","is_oa":true,"landing_page_url":"https://doi.org/10.1136/jcp.34.4.381","pdf_url":"https://jcp.bmj.com/content/jclinpath/34/4/381.full.pdf","source":{"id":"https://openalex.org/S37362813","display_name":"Journal of Clinical Pathology","issn_l":"0021-9746","issn":["0021-9746","1472-4146"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Pathology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1985204716.pdf","grobid_xml":"https://content.openalex.org/works/W1985204716.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W61744271","https://openalex.org/W198570960","https://openalex.org/W1816644756","https://openalex.org/W1973652445","https://openalex.org/W2000612748","https://openalex.org/W2007069571","https://openalex.org/W2028310636","https://openalex.org/W2030719420","https://openalex.org/W2038689414","https://openalex.org/W2075183241","https://openalex.org/W2080693139","https://openalex.org/W2090337281","https://openalex.org/W2135184231","https://openalex.org/W2158778661","https://openalex.org/W2168392298","https://openalex.org/W2319915844","https://openalex.org/W2322850625","https://openalex.org/W2410428784","https://openalex.org/W2411154261","https://openalex.org/W2412002761","https://openalex.org/W2443229597","https://openalex.org/W2444007734","https://openalex.org/W4409122134"],"related_works":["https://openalex.org/W2048927860","https://openalex.org/W118033258","https://openalex.org/W2028310636","https://openalex.org/W2329400014","https://openalex.org/W2414317151","https://openalex.org/W642817484","https://openalex.org/W4385542464","https://openalex.org/W2417716798","https://openalex.org/W187289315","https://openalex.org/W1990424830"],"abstract_inverted_index":{"Ten":[0],"human":[1],"jejunal":[2],"biopsy":[3,79],"specimens":[4,80,103],"were":[5,74],"examined":[6],"by":[7,66],"both":[8,17],"immunofluorescence":[9],"(IF)":[10],"and":[11,21,47,61,96],"immunoperoxidase":[12],"(IP)":[13,95],"methods":[14,68,124],"to":[15,117],"compare":[16],"plasma":[18,114],"cell":[19,72,115],"counts":[20,73,116],"the":[22,54,77,122,126,129],"distribution":[23],"of":[24],"extracellular":[25,111,130],"immunoglobulins.":[26],"Each":[27],"specimen":[28],"was":[29,132],"cut":[30],"into":[31],"at":[32],"least":[33],"two":[34],"portions,":[35],"one":[36],"fixed":[37,57],"in":[38,41,58,63,76],"5%":[39],"formaldehyde":[40],"phosphate-buffered":[42],"saline":[43],"before":[44],"being":[45,56,90],"snap-frozen":[46],"sectioned":[48],"on":[49],"a":[50],"cryostat":[51],"for":[52,69,81,113],"IF,":[53],"other":[55],"half-strength":[59],"Zenker":[60],"embedded":[62],"paraffin":[64],"wax":[65],"standard":[67],"IP.":[70],"Plasma":[71],"comparable":[75],"eight":[78],"which":[82],"they":[83],"could":[84],"be":[85,118],"estimated,":[86],"geometric":[87],"mean":[88],"values":[89],"IgA":[91,112],"22.9":[92],"(IF),":[93,99],"19.3":[94],"IgM":[97],"9.5":[98],"10.6":[100],"(IP).":[101],"Two":[102],"showing":[104],"subtotal":[105],"villous":[106],"atrophy":[107],"had":[108,125],"too":[109],"much":[110],"feasible.":[119],"For":[120],"these":[121],"IF":[123],"advantage":[127],"that":[128],"immunoglobulin":[131],"more":[133],"readily":[134],"distinguishable":[135],"from":[136],"background":[137],"staining.":[138]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}