{"id":"https://openalex.org/W1985160016","doi":"https://doi.org/10.1111/j.1468-1331.2009.02621.x","title":"GRN 3\u2032UTR+78 C>T is not associated with risk for Parkinson\u2019s disease","display_name":"GRN 3\u2032UTR+78 C>T is not associated with risk for Parkinson\u2019s disease","publication_year":2009,"publication_date":"2009-03-31","ids":{"openalex":"https://openalex.org/W1985160016","doi":"https://doi.org/10.1111/j.1468-1331.2009.02621.x","mag":"1985160016","pmid":"https://pubmed.ncbi.nlm.nih.gov/19473366"},"language":"en","primary_location":{"id":"doi:10.1111/j.1468-1331.2009.02621.x","doi":"https://doi.org/10.1111/j.1468-1331.2009.02621.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1468-1331.2009.02621.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1468-1331.2009.02621.x","source":{"id":"https://openalex.org/S162635963","display_name":"European Journal of Neurology","issn_l":"1351-5101","issn":["1351-5101","1468-1331"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1468-1331.2009.02621.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016429635","display_name":"Barbara Jasi\u0144ska\u2010Myga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166182418","display_name":"Medical University of Silesia","ror":"https://ror.org/005k7hp45","country_code":"PL","type":"education","lineage":["https://openalex.org/I166182418"]},{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["PL","US"],"is_corresponding":true,"raw_author_name":"B. Jasinska\u2010Myga","raw_affiliation_strings":["Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA. jasinskamyga.barbara@mayo.edu","Department of Neurology, Aging, Degenerative and Cerebrovascular Disorders, Medical University of Silesia, Katowice, Poland","Department of Neurology, Mayo Clinic, Jacksonville, FL, USA","Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA. jasinskamyga.barbara@mayo.edu","institution_ids":["https://openalex.org/I4210146710"]},{"raw_affiliation_string":"Department of Neurology, Aging, Degenerative and Cerebrovascular Disorders, Medical University of Silesia, Katowice, Poland","institution_ids":["https://openalex.org/I166182418"]},{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I4210146710"]},{"raw_affiliation_string":"Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027534259","display_name":"Christian W. Wider","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Wider","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Jacksonville, FL, USA","Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I4210146710"]},{"raw_affiliation_string":"Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109858833","display_name":"Grzegorz Opala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166182418","display_name":"Medical University of Silesia","ror":"https://ror.org/005k7hp45","country_code":"PL","type":"education","lineage":["https://openalex.org/I166182418"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"G. Opala","raw_affiliation_strings":["Department of Neurology, Aging, Degenerative and Cerebrovascular Disorders, Medical University of Silesia, Katowice, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Aging, Degenerative and Cerebrovascular Disorders, Medical University of Silesia, Katowice, Poland","institution_ids":["https://openalex.org/I166182418"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108587554","display_name":"Anna Krygowska\u2010Wajs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126596746","display_name":"Jagiellonian University","ror":"https://ror.org/03bqmcz70","country_code":"PL","type":"education","lineage":["https://openalex.org/I126596746"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"A. Krygowska\u2010Wajs","raw_affiliation_strings":["Department of Neurology, Collegium Medicum Jagiellonian University, Krakow, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Collegium Medicum Jagiellonian University, Krakow, Poland","institution_ids":["https://openalex.org/I126596746"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067111738","display_name":"Maria Barcikowska","orcid":"https://orcid.org/0000-0001-5657-9670","observed_orcids":["https://orcid.org/0000-0001-5657-9670"]},"institutions":[{"id":"https://openalex.org/I4210157213","display_name":"Mossakowski Medical Research Institute,  Polish Academy of Sciences","ror":"https://ror.org/05d3ntb42","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210157213","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"M. Barcikowska","raw_affiliation_strings":["Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Warsaw, Poland","institution_ids":["https://openalex.org/I4210157213","https://openalex.org/I99542240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050129034","display_name":"K Czy\u017aewski","orcid":"https://orcid.org/0000-0001-7704-7518","observed_orcids":["https://orcid.org/0000-0001-7704-7518"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Czyzewski","raw_affiliation_strings":["Department of Neurology, MSWiA Hospital, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, MSWiA Hospital, Warsaw, Poland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064561010","display_name":"Matthew Baker","orcid":"https://orcid.org/0000-0002-0002-1907","observed_orcids":["https://orcid.org/0000-0002-0002-1907","https://orcid.org/0009-0001-2691-5757"]},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Baker","raw_affiliation_strings":["Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048408999","display_name":"Rosa Rademakers","orcid":"https://orcid.org/0000-0002-4049-0863","observed_orcids":["https://orcid.org/0000-0002-4049-0863"]},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Rademakers","raw_affiliation_strings":["Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009044500","display_name":"Ryan J. Uitti","orcid":"https://orcid.org/0000-0001-8113-4710","observed_orcids":["https://orcid.org/0000-0001-8113-4710"]},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. J. Uitti","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Jacksonville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050824228","display_name":"Matthew James Farrer","orcid":"https://orcid.org/0000-0003-1159-5321","observed_orcids":["https://orcid.org/0000-0003-1159-5321"]},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. J. Farrer","raw_affiliation_strings":["Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074593768","display_name":"Owen A. Ross","orcid":"https://orcid.org/0000-0003-4813-756X","observed_orcids":["https://orcid.org/0000-0003-4813-756X"]},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"O. A. Ross","raw_affiliation_strings":["Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I4210146710"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022481370","display_name":"Zbigniew K. Wszo\u0142ek","orcid":"https://orcid.org/0000-0001-5487-1053","observed_orcids":["https://orcid.org/0000-0001-5487-1053"]},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Z. K. Wszolek","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Jacksonville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I4210146710"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5016429635"],"corresponding_institution_ids":["https://openalex.org/I166182418","https://openalex.org/I4210146710"],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":null,"fwci":0.4176,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.67412156,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"16","issue":"8","first_page":"909","last_page":"911"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.7749000191688538,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.7749000191688538,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.18709999322891235,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.968999981880188},{"id":"https://openalex.org/keywords/progranulin-gene","display_name":"progranulin gene","score":0.9020000100135803},{"id":"https://openalex.org/keywords/gene-regulatory-networks","display_name":"gene regulatory networks","score":0.7419999837875366},{"id":"https://openalex.org/keywords/3-untranslated-region","display_name":"3' untranslated region","score":0.8379999995231628},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9950000047683716},{"id":"https://openalex.org/keywords/microrna-binding-sites","display_name":"microRNA binding sites","score":0.8360000252723694},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.8360000252723694},{"id":"https://openalex.org/keywords/parkinsonism","display_name":"parkinsonism","score":0.7919999957084656}],"concepts":[{"id":"https://openalex.org/C2776939681","wikidata":"https://www.wikidata.org/wiki/Q18579","display_name":"Frontotemporal lobar degeneration","level":5,"score":0.8371970653533936},{"id":"https://openalex.org/C2776525014","wikidata":"https://www.wikidata.org/wiki/Q1531991","display_name":"Parkinsonism","level":3,"score":0.6736618876457214},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6672834157943726},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5773827433586121},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.5521593689918518},{"id":"https://openalex.org/C89604277","wikidata":"https://www.wikidata.org/wiki/Q424345","display_name":"Untranslated region","level":4,"score":0.5061740279197693},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.5047403573989868},{"id":"https://openalex.org/C22667442","wikidata":"https://www.wikidata.org/wiki/Q3272830","display_name":"Three prime untranslated region","level":5,"score":0.44172734022140503},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4394623637199402},{"id":"https://openalex.org/C2778641062","wikidata":"https://www.wikidata.org/wiki/Q18592","display_name":"Frontotemporal dementia","level":4,"score":0.4326515793800354},{"id":"https://openalex.org/C2780427247","wikidata":"https://www.wikidata.org/wiki/Q409961","display_name":"LRRK2","level":4,"score":0.4290100038051605},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4052882790565491},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.36793142557144165},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.32451045513153076},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24478167295455933},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.216742604970932},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14104542136192322},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.13622120022773743}],"mesh":[{"descriptor_ui":"D000077153","descriptor_name":"Progranulins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011044","descriptor_name":"Poland","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D036341","descriptor_name":"Intercellular Signaling Peptides and Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1468-1331.2009.02621.x","doi":"https://doi.org/10.1111/j.1468-1331.2009.02621.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1468-1331.2009.02621.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1468-1331.2009.02621.x","source":{"id":"https://openalex.org/S162635963","display_name":"European Journal of Neurology","issn_l":"1351-5101","issn":["1351-5101","1468-1331"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Neurology","raw_type":"journal-article"},{"id":"pmid:19473366","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19473366","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of neurology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.1468-1331.2009.02621.x","doi":"https://doi.org/10.1111/j.1468-1331.2009.02621.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1468-1331.2009.02621.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1468-1331.2009.02621.x","source":{"id":"https://openalex.org/S162635963","display_name":"European Journal of Neurology","issn_l":"1351-5101","issn":["1351-5101","1468-1331"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G4495269796","display_name":"Genetics and Molecular Biology of Parkinsonism","funder_award_id":"P50NS040256","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000084177","display_name":null,"funder_award_id":"NS40256","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320326292","display_name":"\u015al\u0105ski Uniwersytet Medyczny w Katowicach","ror":null},{"id":"https://openalex.org/F4320328948","display_name":"Uniwersytet \u015al\u0105ski w Katowicach","ror":"https://ror.org/0104rcc94"},{"id":"https://openalex.org/F4320331479","display_name":"Fondation pour la Recherche sur Alzheimer","ror":"https://ror.org/01z0nmr69"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1985160016.pdf","grobid_xml":"https://content.openalex.org/works/W1985160016.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1968231802","https://openalex.org/W1980292758","https://openalex.org/W1993871240","https://openalex.org/W1995715453","https://openalex.org/W1995964483","https://openalex.org/W2008827081","https://openalex.org/W2033867506","https://openalex.org/W2044536672","https://openalex.org/W2046015265","https://openalex.org/W2046015504","https://openalex.org/W2090224607","https://openalex.org/W2090377912","https://openalex.org/W2125948889","https://openalex.org/W2134541041","https://openalex.org/W2142286857","https://openalex.org/W2150523122","https://openalex.org/W2163263839"],"related_works":["https://openalex.org/W2034055545","https://openalex.org/W7096622713","https://openalex.org/W1989561564","https://openalex.org/W2118814738","https://openalex.org/W7098388795","https://openalex.org/W2062305803","https://openalex.org/W1562314847","https://openalex.org/W1995375946","https://openalex.org/W2125948889","https://openalex.org/W2103611965"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"PURPOSE:":[2],"A":[3],"single":[4],"nucleotide":[5],"polymorphism":[6],"in":[7,66,111],"the":[8,12,22,42,56,75,106,112],"3'-untranslated":[9],"region":[10],"of":[11,44,58,63,108],"progranulin":[13],"gene":[14],"(GRN;":[15],"3'UTR+78C>T;":[16],"rs5848)":[17],"was":[18,82],"reported":[19],"to":[20,88],"alter":[21],"risk":[23,62,107],"for":[24],"frontotemporal":[25],"lobar":[26],"degeneration":[27],"with":[28,52],"ubiquitin-positive":[29],"inclusions":[30],"(FTLD-U).":[31],"rs5848":[32,60,85,102],"is":[33],"located":[34],"within":[35],"a":[36],"micro-RNA":[37],"binding":[38],"site":[39],"and":[40,61,77,86,93,114],"affects":[41],"expression":[43],"GRN.":[45],"METHODS:":[46],"As":[47],"FTLD-U":[48],"patients":[49],"often":[50],"present":[51],"parkinsonism,":[53],"we":[54],"investigated":[55],"association":[57,81],"GRN":[59,101],"Parkinson's":[64,89,109],"disease":[65,90,110],"two":[67],"Caucasian":[68],"patient-control":[69],"series":[70,92],"(n":[71],"=":[72],"1413)":[73],"from":[74],"US":[76,113],"Poland.":[78],"RESULTS:":[79],"No":[80],"observed":[83],"between":[84],"susceptibility":[87],"(individual":[91],"combined":[94],"analysis).":[95],"CONCLUSIONS:":[96],"This":[97],"finding":[98],"shows":[99],"that":[100],"does":[103],"not":[104],"affect":[105],"Polish":[115],"populations.":[116]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}