{"id":"https://openalex.org/W1985156459","doi":"https://doi.org/10.1007/s11060-009-9875-7","title":"Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas","display_name":"Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas","publication_year":2009,"publication_date":"2009-04-20","ids":{"openalex":"https://openalex.org/W1985156459","doi":"https://doi.org/10.1007/s11060-009-9875-7","mag":"1985156459","pmid":"https://pubmed.ncbi.nlm.nih.gov/19381449","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2730996"},"language":"en","primary_location":{"id":"doi:10.1007/s11060-009-9875-7","doi":"https://doi.org/10.1007/s11060-009-9875-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11060-009-9875-7","pdf_url":null,"source":{"id":"https://openalex.org/S175922936","display_name":"Journal of Neuro-Oncology","issn_l":"0167-594X","issn":["0167-594X","1573-7373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuro-Oncology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2730996","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012238012","display_name":"Rolf F. Barth","orcid":"https://orcid.org/0000-0002-2616-472X","observed_orcids":["https://orcid.org/0000-0002-2616-472X"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rolf F. Barth","raw_affiliation_strings":["Department of Pathology, The Ohio State University, 165 Hamilton Hall, Columbus, OH 43210, USA. rolf.barth@osumc.edu","the Ohio State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Ohio State University, 165 Hamilton Hall, Columbus, OH 43210, USA. rolf.barth@osumc.edu","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"the Ohio State University","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041131555","display_name":"Balveen Kaur","orcid":"https://orcid.org/0000-0001-7738-0804","observed_orcids":["https://orcid.org/0000-0001-7738-0804"]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Balveen Kaur","raw_affiliation_strings":["Department of Neurological Surgery, Dardinger Laboratory for Neuro-Oncology and Neurosciences, The Ohio State University, 385-D OSUCCC, 410 West 12th Avenue, OSUCCC, Columbus, OH, 43210, USA","the Ohio State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, Dardinger Laboratory for Neuro-Oncology and Neurosciences, The Ohio State University, 385-D OSUCCC, 410 West 12th Avenue, OSUCCC, Columbus, OH, 43210, USA","institution_ids":["https://openalex.org/I2799885155","https://openalex.org/I52357470"]},{"raw_affiliation_string":"the Ohio State University","institution_ids":["https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5041131555"],"corresponding_institution_ids":["https://openalex.org/I2799885155","https://openalex.org/I52357470"],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":3.3703,"has_fulltext":false,"cited_by_count":426,"citation_normalized_percentile":{"value":0.96477495,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"94","issue":"3","first_page":"299","last_page":"312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rat-brain-tumor-model","display_name":"rat brain tumor model","score":0.9769999980926514},{"id":"https://openalex.org/keywords/glioma","display_name":"glioma","score":0.8159999847412109},{"id":"https://openalex.org/keywords/c6-glioma","display_name":"C6 glioma","score":0.9629999995231628},{"id":"https://openalex.org/keywords/9l-gliosarcoma","display_name":"9L gliosarcoma","score":0.9800000190734863},{"id":"https://openalex.org/keywords/f98-glioma","display_name":"F98 glioma","score":0.9940000176429749},{"id":"https://openalex.org/keywords/n-methyl-n-nitrosourea","display_name":"N-methyl-N-nitrosourea","score":0.8600000143051147},{"id":"https://openalex.org/keywords/ethylnitrosourea","display_name":"ethylnitrosourea","score":0.9959999918937683},{"id":"https://openalex.org/keywords/immunogenicity","display_name":"immunogenicity","score":0.6179999709129333},{"id":"https://openalex.org/keywords/syngeneic-tumors","display_name":"syngeneic tumors","score":0.6589999794960022},{"id":"https://openalex.org/keywords/avian-sarcoma-virus","display_name":"avian sarcoma virus","score":0.7739999890327454},{"id":"https://openalex.org/keywords/cancer-cell-lines","display_name":"cancer cell lines","score":0.4519999921321869}],"concepts":[{"id":"https://openalex.org/C2909685333","wikidata":"https://www.wikidata.org/wiki/Q287629","display_name":"Ethylnitrosourea","level":4,"score":0.8448915481567383},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.8232183456420898},{"id":"https://openalex.org/C2779130545","wikidata":"https://www.wikidata.org/wiki/Q233309","display_name":"Brain tumor","level":2,"score":0.622496485710144},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5515369176864624},{"id":"https://openalex.org/C2777295375","wikidata":"https://www.wikidata.org/wiki/Q609503","display_name":"Gliosarcoma","level":3,"score":0.4788822531700134},{"id":"https://openalex.org/C2778681053","wikidata":"https://www.wikidata.org/wiki/Q5569541","display_name":"Glial tumor","level":3,"score":0.4517282545566559},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4437289535999298},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3714293837547302},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.37079328298568726},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35704654455184937},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07542413473129272},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s11060-009-9875-7","doi":"https://doi.org/10.1007/s11060-009-9875-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11060-009-9875-7","pdf_url":null,"source":{"id":"https://openalex.org/S175922936","display_name":"Journal of Neuro-Oncology","issn_l":"0167-594X","issn":["0167-594X","1573-7373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuro-Oncology","raw_type":"journal-article"},{"id":"pmid:19381449","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19381449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuro-oncology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2008207","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2730996","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2730996","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2730996","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Neurooncol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2008207","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2730996","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1430964013","display_name":"OV therapy induced changes in tumor secretome and their impact on therapy","funder_award_id":"R01NS064607","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G6752953880","display_name":"Oncolytic HSV Cancer Therapy:  Enhancement by Vasculostatin Gene Therapy","funder_award_id":"R21NS056203","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G7226936174","display_name":"Enhancing viral oncolysis with vasculostatin gene delivery","funder_award_id":"R01CA150153","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8244989655","display_name":"Combination of Cliengitide and Oncolytic HSV: a toxicology study for brain tumors","funder_award_id":"K01NS059575","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":155,"referenced_works":["https://openalex.org/W27942811","https://openalex.org/W55858921","https://openalex.org/W60890105","https://openalex.org/W191454705","https://openalex.org/W1410898516","https://openalex.org/W1505550085","https://openalex.org/W1514871629","https://openalex.org/W1520602750","https://openalex.org/W1534679825","https://openalex.org/W1572502534","https://openalex.org/W1602045090","https://openalex.org/W1751389110","https://openalex.org/W1784848985","https://openalex.org/W1791027840","https://openalex.org/W1813936612","https://openalex.org/W1898544988","https://openalex.org/W1947016183","https://openalex.org/W1968723149","https://openalex.org/W1968782197","https://openalex.org/W1969311117","https://openalex.org/W1972283139","https://openalex.org/W1972365556","https://openalex.org/W1972887015","https://openalex.org/W1976771686","https://openalex.org/W1978150732","https://openalex.org/W1979126499","https://openalex.org/W1979339714","https://openalex.org/W1979467387","https://openalex.org/W1980146494","https://openalex.org/W1987342867","https://openalex.org/W1988184011","https://openalex.org/W1990622746","https://openalex.org/W1990738833","https://openalex.org/W1990918868","https://openalex.org/W1993467626","https://openalex.org/W1999088458","https://openalex.org/W2000626199","https://openalex.org/W2002185925","https://openalex.org/W2002631809","https://openalex.org/W2002975415","https://openalex.org/W2003703284","https://openalex.org/W2003769078","https://openalex.org/W2004824016","https://openalex.org/W2005410380","https://openalex.org/W2009275789","https://openalex.org/W2010123543","https://openalex.org/W2010618825","https://openalex.org/W2014821033","https://openalex.org/W2015703347","https://openalex.org/W2017562040","https://openalex.org/W2017816173","https://openalex.org/W2019754652","https://openalex.org/W2020821501","https://openalex.org/W2022901657","https://openalex.org/W2022957248","https://openalex.org/W2023111062","https://openalex.org/W2026936875","https://openalex.org/W2027060977","https://openalex.org/W2027132725","https://openalex.org/W2028264270","https://openalex.org/W2029011957","https://openalex.org/W2030586180","https://openalex.org/W2030755036","https://openalex.org/W2031098493","https://openalex.org/W2032946473","https://openalex.org/W2035033765","https://openalex.org/W2035109568","https://openalex.org/W2036164831","https://openalex.org/W2037877043","https://openalex.org/W2039279159","https://openalex.org/W2039786298","https://openalex.org/W2040668447","https://openalex.org/W2043406624","https://openalex.org/W2045388058","https://openalex.org/W2045675145","https://openalex.org/W2046147812","https://openalex.org/W2047275511","https://openalex.org/W2048042899","https://openalex.org/W2051222516","https://openalex.org/W2054636085","https://openalex.org/W2054801826","https://openalex.org/W2055177877","https://openalex.org/W2059768085","https://openalex.org/W2060075467","https://openalex.org/W2064949874","https://openalex.org/W2065300033","https://openalex.org/W2066640676","https://openalex.org/W2066986960","https://openalex.org/W2068181649","https://openalex.org/W2068485719","https://openalex.org/W2069939109","https://openalex.org/W2070317195","https://openalex.org/W2075158458","https://openalex.org/W2076267708","https://openalex.org/W2076378464","https://openalex.org/W2076479500","https://openalex.org/W2077384493","https://openalex.org/W2079687409","https://openalex.org/W2085994483","https://openalex.org/W2094442197","https://openalex.org/W2095143201","https://openalex.org/W2096106209","https://openalex.org/W2097764649","https://openalex.org/W2101082342","https://openalex.org/W2101410624","https://openalex.org/W2104444603","https://openalex.org/W2104605014","https://openalex.org/W2108417705","https://openalex.org/W2110741904","https://openalex.org/W2113128219","https://openalex.org/W2116917673","https://openalex.org/W2116971506","https://openalex.org/W2119061611","https://openalex.org/W2119472742","https://openalex.org/W2119482835","https://openalex.org/W2126085321","https://openalex.org/W2126707307","https://openalex.org/W2127198442","https://openalex.org/W2131666965","https://openalex.org/W2131670056","https://openalex.org/W2132356037","https://openalex.org/W2132729928","https://openalex.org/W2133295582","https://openalex.org/W2141377500","https://openalex.org/W2144283038","https://openalex.org/W2144909107","https://openalex.org/W2147522400","https://openalex.org/W2148276738","https://openalex.org/W2148641166","https://openalex.org/W2152127384","https://openalex.org/W2154156201","https://openalex.org/W2155049976","https://openalex.org/W2160374246","https://openalex.org/W2163695893","https://openalex.org/W2165757582","https://openalex.org/W2165778860","https://openalex.org/W2168672718","https://openalex.org/W2170692060","https://openalex.org/W2172096869","https://openalex.org/W2174292143","https://openalex.org/W2217980179","https://openalex.org/W2277775931","https://openalex.org/W2313220981","https://openalex.org/W2318537454","https://openalex.org/W2321832715","https://openalex.org/W2322657289","https://openalex.org/W2322684614","https://openalex.org/W2324647996","https://openalex.org/W2329507162","https://openalex.org/W2334872306","https://openalex.org/W2395205935","https://openalex.org/W2407175930","https://openalex.org/W2414852757","https://openalex.org/W3147886376","https://openalex.org/W4250573857"],"related_works":["https://openalex.org/W80995886","https://openalex.org/W191454705","https://openalex.org/W4224232488","https://openalex.org/W107825186","https://openalex.org/W33933549","https://openalex.org/W2064665995","https://openalex.org/W1988184011","https://openalex.org/W2126085321","https://openalex.org/W1582149581","https://openalex.org/W2010519130"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":24},{"year":2024,"cited_by_count":22},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":23},{"year":2020,"cited_by_count":32},{"year":2019,"cited_by_count":24},{"year":2018,"cited_by_count":28},{"year":2017,"cited_by_count":38},{"year":2016,"cited_by_count":35},{"year":2015,"cited_by_count":22},{"year":2014,"cited_by_count":30},{"year":2013,"cited_by_count":28},{"year":2012,"cited_by_count":31}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
