{"id":"https://openalex.org/W1985089425","doi":"https://doi.org/10.1016/j.jaci.2011.01.027","title":"Advances in mechanisms of asthma, allergy, and immunology in 2010","display_name":"Advances in mechanisms of asthma, allergy, and immunology in 2010","publication_year":2011,"publication_date":"2011-03-01","ids":{"openalex":"https://openalex.org/W1985089425","doi":"https://doi.org/10.1016/j.jaci.2011.01.027","mag":"1985089425","pmid":"https://pubmed.ncbi.nlm.nih.gov/21377038"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaci.2011.01.027","doi":"https://doi.org/10.1016/j.jaci.2011.01.027","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaci.2011.01.027","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012660316","display_name":"David H. Broide","orcid":"https://orcid.org/0000-0001-8405-9090","observed_orcids":["https://orcid.org/0000-0001-8405-9090"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David H. Broide","raw_affiliation_strings":["Department of Medicine, Section of Allergy and Immunology, University of California at San Diego, Calif, USA","Department of Medicine, Section of Allergy and Immunology, University of California at San Diego, Calif"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Section of Allergy and Immunology, University of California at San Diego, Calif, USA","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Department of Medicine, Section of Allergy and Immunology, University of California at San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036569483","display_name":"Fred D. Finkelman","orcid":"https://orcid.org/0000-0002-1815-1902","observed_orcids":["https://orcid.org/0000-0002-1815-1902"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]},{"id":"https://openalex.org/I4210143084","display_name":"Cincinnati VA Medical Center","ror":"https://ror.org/045r80n66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210127612","https://openalex.org/I4210143084"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fred Finkelman","raw_affiliation_strings":["Cincinnati Veterans Affairs Medical Center and the Division of Immunology, University of Cincinnati College of Medicine, Cincinnati, Ohio","Division of Immunobiology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Veterans Affairs Medical Center and the Division of Immunology, University of Cincinnati College of Medicine, Cincinnati, Ohio","institution_ids":["https://openalex.org/I4210143084","https://openalex.org/I63135867"]},{"raw_affiliation_string":"Division of Immunobiology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004888276","display_name":"Bruce Scott Bochner","orcid":"https://orcid.org/0000-0002-9411-6009","observed_orcids":["https://orcid.org/0000-0002-9411-6009"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce S. Bochner","raw_affiliation_strings":["Department of Medicine, Division of Allergy and Clinical Immunology, the Johns Hopkins University School of Medicine, Johns Hopkins Asthma and Allergy Center, Baltimore, Md"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Allergy and Clinical Immunology, the Johns Hopkins University School of Medicine, Johns Hopkins Asthma and Allergy Center, Baltimore, Md","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100715040","display_name":"Marc E. Rothenberg","orcid":"https://orcid.org/0000-0001-9790-6332","observed_orcids":["https://orcid.org/0000-0001-9790-6332"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marc E. Rothenberg","raw_affiliation_strings":["Division of Allergy and Immunology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Allergy and Immunology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio","institution_ids":["https://openalex.org/I1285204247"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5100715040"],"corresponding_institution_ids":["https://openalex.org/I1285204247"],"apc_list":{"value":4900,"currency":"USD","value_usd":4900},"apc_paid":null,"fwci":3.2302,"has_fulltext":false,"cited_by_count":172,"citation_normalized_percentile":{"value":0.96098901,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"127","issue":"3","first_page":"689","last_page":"695"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asthma-pathogenesis","display_name":"asthma pathogenesis","score":0.8790000081062317},{"id":"https://openalex.org/keywords/allergic-inflammation","display_name":"allergic inflammation","score":0.9829999804496765},{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.8759999871253967},{"id":"https://openalex.org/keywords/eosinophils","display_name":"eosinophils","score":0.9959999918937683},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.9890000224113464},{"id":"https://openalex.org/keywords/t-cells","display_name":"T cells","score":0.9779999852180481},{"id":"https://openalex.org/keywords/ige","display_name":"IgE","score":0.9549999833106995},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.9819999933242798},{"id":"https://openalex.org/keywords/signaling-pathways","display_name":"signaling pathways","score":0.6850000023841858},{"id":"https://openalex.org/keywords/eosinophilic-esophagitis","display_name":"eosinophilic esophagitis","score":0.9929999709129333},{"id":"https://openalex.org/keywords/food-allergy","display_name":"food allergy","score":1.0},{"id":"https://openalex.org/keywords/anaphylaxis","display_name":"anaphylaxis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/immediate-hypersensitivity","display_name":"immediate hypersensitivity","score":0.9160000085830688},{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.9470000267028809},{"id":"https://openalex.org/keywords/nasal-polyps","display_name":"nasal polyps","score":0.9940000176429749},{"id":"https://openalex.org/keywords/hypereosinophilic-syndrome","display_name":"hypereosinophilic syndrome","score":0.9649999737739563},{"id":"https://openalex.org/keywords/genetic-susceptibility-to-allergy","display_name":"genetic susceptibility to allergy","score":0.5699999928474426}],"concepts":[{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.7057737112045288},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6619505882263184},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.653883159160614},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5368536114692688}],"mesh":[{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004804","descriptor_name":"Eosinophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006967","descriptor_name":"Hypersensitivity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008407","descriptor_name":"Mast Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.jaci.2011.01.027","doi":"https://doi.org/10.1016/j.jaci.2011.01.027","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaci.2011.01.027","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},{"id":"pmid:21377038","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21377038","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of allergy and clinical immunology","raw_type":"Journal Article"},{"id":"pmid:22284930","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22284930","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of allergy and clinical immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320314903","display_name":"Immune Tolerance Network","ror":"https://ror.org/00pjnm784"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":165,"referenced_works":["https://openalex.org/W153388856","https://openalex.org/W1625157530","https://openalex.org/W1786542967","https://openalex.org/W1927845013","https://openalex.org/W1963647742","https://openalex.org/W1966197639","https://openalex.org/W1967424174","https://openalex.org/W1967926844","https://openalex.org/W1968094755","https://openalex.org/W1968639181","https://openalex.org/W1968704028","https://openalex.org/W1969767887","https://openalex.org/W1970537760","https://openalex.org/W1970678723","https://openalex.org/W1971803390","https://openalex.org/W1972474621","https://openalex.org/W1973977796","https://openalex.org/W1975217164","https://openalex.org/W1976404009","https://openalex.org/W1977436614","https://openalex.org/W1977547183","https://openalex.org/W1977639139","https://openalex.org/W1977885071","https://openalex.org/W1977953521","https://openalex.org/W1978011585","https://openalex.org/W1979212540","https://openalex.org/W1979466963","https://openalex.org/W1982499259","https://openalex.org/W1983314876","https://openalex.org/W1990603544","https://openalex.org/W1990716742","https://openalex.org/W1990907145","https://openalex.org/W1991423884","https://openalex.org/W1991696350","https://openalex.org/W1992780020","https://openalex.org/W1993745762","https://openalex.org/W1995552142","https://openalex.org/W1997082965","https://openalex.org/W1998444876","https://openalex.org/W2002122451","https://openalex.org/W2002362079","https://openalex.org/W2003100495","https://openalex.org/W2003381671","https://openalex.org/W2003779030","https://openalex.org/W2004028427","https://openalex.org/W2004828096","https://openalex.org/W2005546041","https://openalex.org/W2005694123","https://openalex.org/W2009083228","https://openalex.org/W2013398275","https://openalex.org/W2013728662","https://openalex.org/W2013863016","https://openalex.org/W2014115378","https://openalex.org/W2015663870","https://openalex.org/W2017125863","https://openalex.org/W2019604250","https://openalex.org/W2019632225","https://openalex.org/W2020998786","https://openalex.org/W2022487754","https://openalex.org/W2027263153","https://openalex.org/W2028420976","https://openalex.org/W2030389672","https://openalex.org/W2030979378","https://openalex.org/W2031640798","https://openalex.org/W2032405768","https://openalex.org/W2033392452","https://openalex.org/W2033732960","https://openalex.org/W2033975621","https://openalex.org/W2034664214","https://openalex.org/W2035831689","https://openalex.org/W2036192256","https://openalex.org/W2036694301","https://openalex.org/W2040229433","https://openalex.org/W2043133666","https://openalex.org/W2044763085","https://openalex.org/W2051583408","https://openalex.org/W2051930718","https://openalex.org/W2053371648","https://openalex.org/W2057192777","https://openalex.org/W2058789166","https://openalex.org/W2059392211","https://openalex.org/W2060944699","https://openalex.org/W2060981449","https://openalex.org/W2061374868","https://openalex.org/W2063014521","https://openalex.org/W2063316222","https://openalex.org/W2071303461","https://openalex.org/W2073959308","https://openalex.org/W2074824929","https://openalex.org/W2075084409","https://openalex.org/W2075763559","https://openalex.org/W2076862915","https://openalex.org/W2077155241","https://openalex.org/W2077828869","https://openalex.org/W2078706891","https://openalex.org/W2079482489","https://openalex.org/W2079824568","https://openalex.org/W2080725704","https://openalex.org/W2081625575","https://openalex.org/W2081698746","https://openalex.org/W2081964512","https://openalex.org/W2084543776","https://openalex.org/W2085754352","https://openalex.org/W2086958200","https://openalex.org/W2087691206","https://openalex.org/W2088341199","https://openalex.org/W2090199831","https://openalex.org/W2091748474","https://openalex.org/W2094472942","https://openalex.org/W2094849429","https://openalex.org/W2095523733","https://openalex.org/W2096891194","https://openalex.org/W2097374308","https://openalex.org/W2098968578","https://openalex.org/W2102930679","https://openalex.org/W2104894967","https://openalex.org/W2108241262","https://openalex.org/W2110943096","https://openalex.org/W2112520921","https://openalex.org/W2113624460","https://openalex.org/W2114554839","https://openalex.org/W2116311099","https://openalex.org/W2118059740","https://openalex.org/W2118590252","https://openalex.org/W2120018683","https://openalex.org/W2122473629","https://openalex.org/W2125178177","https://openalex.org/W2125330175","https://openalex.org/W2126604514","https://openalex.org/W2127203245","https://openalex.org/W2127623109","https://openalex.org/W2127965296","https://openalex.org/W2128104166","https://openalex.org/W2128553167","https://openalex.org/W2129238377","https://openalex.org/W2131055763","https://openalex.org/W2133049833","https://openalex.org/W2133204970","https://openalex.org/W2135350762","https://openalex.org/W2135683336","https://openalex.org/W2136252136","https://openalex.org/W2136918536","https://openalex.org/W2137821258","https://openalex.org/W2138169844","https://openalex.org/W2140083164","https://openalex.org/W2142297198","https://openalex.org/W2145762862","https://openalex.org/W2145774897","https://openalex.org/W2147033690","https://openalex.org/W2147530876","https://openalex.org/W2147750411","https://openalex.org/W2148603662","https://openalex.org/W2149723200","https://openalex.org/W2153841906","https://openalex.org/W2154777347","https://openalex.org/W2155612793","https://openalex.org/W2156476158","https://openalex.org/W2156480965","https://openalex.org/W2158614332","https://openalex.org/W2160258195","https://openalex.org/W2161554633","https://openalex.org/W2162590783","https://openalex.org/W2166544113","https://openalex.org/W2166698716","https://openalex.org/W2170151520"],"related_works":["https://openalex.org/W4239187852","https://openalex.org/W2115983398","https://openalex.org/W4409510873","https://openalex.org/W2505803711","https://openalex.org/W2416921693","https://openalex.org/W2732050939","https://openalex.org/W2223515445","https://openalex.org/W4241838930","https://openalex.org/W2185890281","https://openalex.org/W7064259626"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":16},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":17},{"year":2013,"cited_by_count":23},{"year":2012,"cited_by_count":32}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}