{"id":"https://openalex.org/W1985013718","doi":"https://doi.org/10.1053/jlts.2000.18499","title":"Impact of liver transplantation on health-related quality of life","display_name":"Impact of liver transplantation on health-related quality of life","publication_year":2000,"publication_date":"2000-11-01","ids":{"openalex":"https://openalex.org/W1985013718","doi":"https://doi.org/10.1053/jlts.2000.18499","mag":"1985013718","pmid":"https://pubmed.ncbi.nlm.nih.gov/11084068"},"language":"en","primary_location":{"id":"doi:10.1053/jlts.2000.18499","doi":"https://doi.org/10.1053/jlts.2000.18499","is_oa":false,"landing_page_url":"https://doi.org/10.1053/jlts.2000.18499","pdf_url":null,"source":{"id":"https://openalex.org/S205547219","display_name":"Liver Transplantation","issn_l":"1527-6465","issn":["1527-6465","1527-6473"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Liver Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109960427","display_name":"Zobair M. Younossi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I2800468613","display_name":"Inova Fairfax Hospital","ror":"https://ror.org/0212h5y77","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I116530498","https://openalex.org/I2800468613"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Zobair M. Younossi","raw_affiliation_strings":["Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH, USA. zobair.younossi@inova.com","\u2225Center for Liver Diseases, Inova Fairfax Hospital, Falls Church, VA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH, USA. zobair.younossi@inova.com","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"\u2225Center for Liver Diseases, Inova Fairfax Hospital, Falls Church, VA","institution_ids":["https://openalex.org/I2800468613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111574605","display_name":"Marilyn McCormick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marilyn McCormick","raw_affiliation_strings":["Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041756550","display_name":"Lori Lyn Price","orcid":"https://orcid.org/0000-0003-0664-8978","observed_orcids":["https://orcid.org/0000-0003-0664-8978"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lori Lyn Price","raw_affiliation_strings":["Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049019266","display_name":"Navdeep Boparai","orcid":"https://orcid.org/0000-0003-1790-2169","observed_orcids":["https://orcid.org/0000-0003-1790-2169"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Navdeep Boparai","raw_affiliation_strings":["Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113686559","display_name":"Lou Farquhar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lou Farquhar","raw_affiliation_strings":["Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111926423","display_name":"J. Michael Henderson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J. Henderson","raw_affiliation_strings":["Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Liver Transplant Center, The Cleveland Clinic Foundation, Cleveland, OH","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110892715","display_name":"Gordon Guyatt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801259263","display_name":"McMaster University Medical Centre","ror":"https://ror.org/05jyrng31","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801259263","https://openalex.org/I76442945"]},{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Gordon Guyatt","raw_affiliation_strings":["Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada","institution_ids":["https://openalex.org/I2801259263","https://openalex.org/I98251732"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5109960427"],"corresponding_institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I2800468613"],"apc_list":{"value":2150,"currency":"USD","value_usd":2150},"apc_paid":null,"fwci":3.8272,"has_fulltext":false,"cited_by_count":98,"citation_normalized_percentile":{"value":0.9307463,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"6","issue":"6","first_page":"779","last_page":"783"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.03290000185370445,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.9350000023841858},{"id":"https://openalex.org/keywords/liver-transplant-candidates","display_name":"liver transplant candidates","score":0.8759999871253967},{"id":"https://openalex.org/keywords/chronic-liver-disease-questionnaire","display_name":"Chronic Liver Disease Questionnaire","score":0.800000011920929},{"id":"https://openalex.org/keywords/sf-36","display_name":"SF-36","score":0.9819999933242798},{"id":"https://openalex.org/keywords/child-pugh-score","display_name":"Child-Pugh score","score":0.9649999737739563},{"id":"https://openalex.org/keywords/congestive-heart-failure","display_name":"congestive heart failure","score":0.7979999780654907},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mental-health","display_name":"mental health","score":0.5789999961853027},{"id":"https://openalex.org/keywords/physical-functioning","display_name":"physical function","score":0.5320000052452087}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.94740229845047},{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.7172051668167114},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.7073685526847839},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.6093901991844177},{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.6080464124679565},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5805366635322571},{"id":"https://openalex.org/C2779102576","wikidata":"https://www.wikidata.org/wiki/Q5113984","display_name":"Chronic liver disease","level":3,"score":0.5196689367294312},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.48079076409339905},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.40950095653533936},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.343461275100708},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.1513330042362213},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.11043211817741394},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011184","descriptor_name":"Postoperative Period","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016031","descriptor_name":"Liver Transplantation","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1053/jlts.2000.18499","doi":"https://doi.org/10.1053/jlts.2000.18499","is_oa":false,"landing_page_url":"https://doi.org/10.1053/jlts.2000.18499","pdf_url":null,"source":{"id":"https://openalex.org/S205547219","display_name":"Liver Transplantation","issn_l":"1527-6465","issn":["1527-6465","1527-6473"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Liver Transplantation","raw_type":"journal-article"},{"id":"pmid:11084068","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11084068","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W297652177","https://openalex.org/W1954511783","https://openalex.org/W1970449031","https://openalex.org/W1974501571","https://openalex.org/W1975285483","https://openalex.org/W1999616939","https://openalex.org/W2028963317","https://openalex.org/W2037377025","https://openalex.org/W2048630590","https://openalex.org/W2053164540","https://openalex.org/W2054032040","https://openalex.org/W2054575608","https://openalex.org/W2060123467","https://openalex.org/W2081248103","https://openalex.org/W2082007751","https://openalex.org/W2097667004","https://openalex.org/W2111431492","https://openalex.org/W2143468834","https://openalex.org/W2335592397","https://openalex.org/W2403740572","https://openalex.org/W2408646082","https://openalex.org/W2413385973","https://openalex.org/W2413553039","https://openalex.org/W2463502112","https://openalex.org/W4246147341","https://openalex.org/W4292806894"],"related_works":["https://openalex.org/W2031033092","https://openalex.org/W2084023071","https://openalex.org/W2113456202","https://openalex.org/W2073269828","https://openalex.org/W4285189910","https://openalex.org/W4411698230","https://openalex.org/W2003401145","https://openalex.org/W2021818188","https://openalex.org/W1604498738","https://openalex.org/W2072501082"],"abstract_inverted_index":{"This":[0],"study":[1],"is":[2],"designed":[3],"to":[4,175,186],"measure":[5],"the":[6,65,139,151,180,207],"impact":[7],"of":[8,17,21,56,64,145,164,167,179,191,194,219,222],"orthotopic":[9],"liver":[10,40,57,82,123,146],"transplantation":[11],"(OLT)":[12],"on":[13],"patients'":[14],"health-related":[15,22,165,192,220],"quality":[16,166,193,221],"life.":[18],"Two":[19],"types":[20],"quality-of-life":[23,118],"questionnaires":[24],"were":[25,60,85,125,204,212],"administered":[26],"at":[27],"baseline":[28],"and":[29,39,51,68,75,89,110,134,136,143,169,177,200,216],"after":[30,198],"OLT:":[31],"generic":[32],"(Medical":[33],"Outcomes":[34],"Study":[35],"Short":[36],"Form":[37],"36)":[38],"specific":[41],"(Chronic":[42],"Liver":[43],"Disease":[44],"Questionnaire).":[45],"We":[46],"also":[47],"recorded":[48],"clinical,":[49],"demographic,":[50],"laboratory":[52],"data.":[53],"Pre-OLT":[54],"scores":[55,119,203],"transplant":[58,83],"candidates":[59,84],"compared":[61],"with":[62,70,132],"those":[63,129,137],"general":[66,140],"population":[67,208],"patients":[69,121,131],"congestive":[71],"heart":[72],"failure":[73],"(CHF)":[74],"chronic":[76],"obstructive":[77],"pulmonary":[78],"disease":[79,147],"(COPD).":[80],"Thirty-seven":[81],"evaluated:":[86],"25":[87],"men":[88],"12":[90,95],"women;":[91],"age,":[92],"50.2":[93],"+/-":[94,115],"years;":[96],"Child's":[97],"class":[98,102,106],"A,":[99],"3":[100],"patients;":[101,105,109],"B,":[103],"30":[104],"C,":[107],"4":[108],"galactose":[111],"elimination":[112],"capacity,":[113],"277":[114],"81.":[116],"Health-related":[117],"for":[120,130],"awaiting":[122],"transplants":[124],"significantly":[126,196],"lower":[127],"than":[128],"COPD":[133],"CHF":[135],"in":[138,214],"population.":[141],"Sex":[142],"cause":[144],"did":[148],"not":[149],"affect":[150],"scores.":[152],"There":[153],"was":[154],"a":[155],"weak":[156],"but":[157,224],"significant":[158],"inverse":[159],"correlation":[160],"between":[161],"some":[162,225],"aspects":[163,190,218],"life":[168,195],"both":[170],"age":[171],"(r":[172,183],"=":[173,184],"-0.31":[174],"-0.34)":[176],"worsening":[178],"Child-Pugh":[181],"score":[182],"-0.32":[185],"-0.43).":[187],"All":[188],"measured":[189],"improved":[197],"OLT,":[199],"mental":[201],"health":[202],"indistinguishable":[205],"from":[206],"norms.":[209],"Similar":[210],"improvements":[211],"evident":[213],"physical":[215],"disease-specific":[217],"life,":[223],"residual":[226],"dysfunction":[227],"persisted.":[228]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}