{"id":"https://openalex.org/W1985012537","doi":"https://doi.org/10.3109/0886022x.2014.991263","title":"Effects of melatonin on the serum levels of pro-inflammatory cytokines and tissue injury after renal ischemia reperfusion in rats","display_name":"Effects of melatonin on the serum levels of pro-inflammatory cytokines and tissue injury after renal ischemia reperfusion in rats","publication_year":2014,"publication_date":"2014-12-18","ids":{"openalex":"https://openalex.org/W1985012537","doi":"https://doi.org/10.3109/0886022x.2014.991263","mag":"1985012537","pmid":"https://pubmed.ncbi.nlm.nih.gov/25519208"},"language":"en","primary_location":{"id":"doi:10.3109/0886022x.2014.991263","doi":"https://doi.org/10.3109/0886022x.2014.991263","is_oa":true,"landing_page_url":"https://doi.org/10.3109/0886022x.2014.991263","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/0886022X.2014.991263?needAccess=true&role=button","source":{"id":"https://openalex.org/S159051371","display_name":"Renal Failure","issn_l":"0886-022X","issn":["0886-022X","1525-6049"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Renal Failure","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.3109/0886022X.2014.991263?needAccess=true&role=button","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019675478","display_name":"Eli\u0307f O\u011fuz","orcid":"https://orcid.org/0000-0002-8052-671X","observed_orcids":["https://orcid.org/0000-0002-8052-671X"]},"institutions":[{"id":"https://openalex.org/I80538482","display_name":"Harran University","ror":"https://ror.org/057qfs197","country_code":"TR","type":"education","lineage":["https://openalex.org/I80538482"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Elif Oguz","raw_affiliation_strings":["Department of Pharmacology, Faculty of Medicine, Harran University, Sanliurfa, Turkey,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Faculty of Medicine, Harran University, Sanliurfa, Turkey,","institution_ids":["https://openalex.org/I80538482"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zehra Yilmaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80538482","display_name":"Harran University","ror":"https://ror.org/057qfs197","country_code":"TR","type":"education","lineage":["https://openalex.org/I80538482"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Zehra Yilmaz","raw_affiliation_strings":["Department of Pharmacology, Faculty of Medicine, Harran University, Sanliurfa, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Faculty of Medicine, Harran University, Sanliurfa, Turkey","institution_ids":["https://openalex.org/I80538482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026694770","display_name":"Hatice \u00d6zbilge","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87673952","display_name":"Erciyes University","ror":"https://ror.org/047g8vk19","country_code":"TR","type":"education","lineage":["https://openalex.org/I87673952"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Hatice Ozbilge","raw_affiliation_strings":["Department of Microbiology, Faculty of Pharmacy, Erciyes University, Kayseri, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Pharmacy, Erciyes University, Kayseri, Turkey","institution_ids":["https://openalex.org/I87673952"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108490637","display_name":"F\u00fcsun Baba","orcid":"https://orcid.org/0000-0002-3091-5020","observed_orcids":["https://orcid.org/0000-0002-3091-5020"]},"institutions":[{"id":"https://openalex.org/I137996928","display_name":"Sel\u00e7uk University","ror":"https://ror.org/045hgzm75","country_code":"TR","type":"education","lineage":["https://openalex.org/I137996928"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Fusun Baba","raw_affiliation_strings":["Department of Pathology, Faculty of Medicine, Selcuk University, Konya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Faculty of Medicine, Selcuk University, Konya, Turkey","institution_ids":["https://openalex.org/I137996928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036455316","display_name":"Suzan Tabur","orcid":"https://orcid.org/0000-0002-5936-2888","observed_orcids":["https://orcid.org/0000-0002-5936-2888"]},"institutions":[{"id":"https://openalex.org/I59738393","display_name":"Gaziantep University","ror":"https://ror.org/020vvc407","country_code":"TR","type":"education","lineage":["https://openalex.org/I59738393"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Suzan Tabur","raw_affiliation_strings":["Department of Endocrinology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey","institution_ids":["https://openalex.org/I59738393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056922021","display_name":"M\u00fckerrem Bet\u00fcl Yerer","orcid":"https://orcid.org/0000-0002-4503-8032","observed_orcids":["https://orcid.org/0000-0002-4503-8032"]},"institutions":[{"id":"https://openalex.org/I87673952","display_name":"Erciyes University","ror":"https://ror.org/047g8vk19","country_code":"TR","type":"education","lineage":["https://openalex.org/I87673952"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mukerrem Betul Yerer","raw_affiliation_strings":["Department of Pharmacology, Faculty of Pharmacy, Erciyes University, Kayseri, Turkey, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Faculty of Pharmacy, Erciyes University, Kayseri, Turkey, and","institution_ids":["https://openalex.org/I87673952"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036121864","display_name":"A\u015fk\u0131n Hekimo\u011flu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123466251","display_name":"Dicle University","ror":"https://ror.org/0257dtg16","country_code":"TR","type":"education","lineage":["https://openalex.org/I123466251"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Askin Hekimoglu","raw_affiliation_strings":["Department of Pharmacology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey","institution_ids":["https://openalex.org/I123466251"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5019675478"],"corresponding_institution_ids":["https://openalex.org/I80538482"],"apc_list":{"value":1880,"currency":"GBP","value_usd":2306},"apc_paid":null,"fwci":0.7396,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.71371354,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"37","issue":"2","first_page":"318","last_page":"322"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.7279999852180481,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.7279999852180481,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.23389999568462372,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13796","display_name":"Neuroprotection in Cerebral Ischemia","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/melatonin","display_name":"melatonin","score":1.0},{"id":"https://openalex.org/keywords/renal-ischemia-reperfusion-injury","display_name":"renal ischemia-reperfusion injury","score":0.8669999837875366},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8999999761581421},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":1.0},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.9990000128746033},{"id":"https://openalex.org/keywords/renal-tissue-injury","display_name":"renal tissue injury","score":0.5569999814033508},{"id":"https://openalex.org/keywords/lps-induced-inflammation","display_name":"lipopolysaccharide-induced inflammation","score":0.871999979019165},{"id":"https://openalex.org/keywords/renal-protection","display_name":"renal protection","score":0.503000020980835}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9045789241790771},{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.8811094760894775},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.66124427318573},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.6329267024993896},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6031347513198853},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.5894235372543335},{"id":"https://openalex.org/C2780721119","wikidata":"https://www.wikidata.org/wiki/Q7312492","display_name":"Renal ischemia","level":4,"score":0.5423908233642578},{"id":"https://openalex.org/C2780114680","wikidata":"https://www.wikidata.org/wiki/Q1413991","display_name":"Reperfusion injury","level":3,"score":0.4967370629310608},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.4943504333496094},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.4698551893234253},{"id":"https://openalex.org/C2778754761","wikidata":"https://www.wikidata.org/wiki/Q421804","display_name":"Lipopolysaccharide","level":2,"score":0.45377853512763977},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4229722023010254},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.4198358654975891}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001685","descriptor_name":"Biological Factors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008550","descriptor_name":"Melatonin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015427","descriptor_name":"Reperfusion Injury","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015427","descriptor_name":"Reperfusion Injury","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3109/0886022x.2014.991263","doi":"https://doi.org/10.3109/0886022x.2014.991263","is_oa":true,"landing_page_url":"https://doi.org/10.3109/0886022x.2014.991263","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/0886022X.2014.991263?needAccess=true&role=button","source":{"id":"https://openalex.org/S159051371","display_name":"Renal Failure","issn_l":"0886-022X","issn":["0886-022X","1525-6049"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Renal Failure","raw_type":"journal-article"},{"id":"pmid:25519208","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25519208","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Renal failure","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3109/0886022x.2014.991263","doi":"https://doi.org/10.3109/0886022x.2014.991263","is_oa":true,"landing_page_url":"https://doi.org/10.3109/0886022x.2014.991263","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/0886022X.2014.991263?needAccess=true&role=button","source":{"id":"https://openalex.org/S159051371","display_name":"Renal Failure","issn_l":"0886-022X","issn":["0886-022X","1525-6049"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Renal Failure","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1985012537.pdf","grobid_xml":"https://content.openalex.org/works/W1985012537.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W11766024","https://openalex.org/W63098812","https://openalex.org/W1488169883","https://openalex.org/W1936195323","https://openalex.org/W1965714703","https://openalex.org/W1967419252","https://openalex.org/W1971799714","https://openalex.org/W1975713973","https://openalex.org/W1993447091","https://openalex.org/W1996271604","https://openalex.org/W2001377500","https://openalex.org/W2016685007","https://openalex.org/W2022306256","https://openalex.org/W2025517512","https://openalex.org/W2029223007","https://openalex.org/W2041379622","https://openalex.org/W2045668642","https://openalex.org/W2052868303","https://openalex.org/W2058728334","https://openalex.org/W2069784526","https://openalex.org/W2073288798","https://openalex.org/W2073342144","https://openalex.org/W2081141861","https://openalex.org/W2086535669","https://openalex.org/W2093240252","https://openalex.org/W2093539277","https://openalex.org/W2101754323","https://openalex.org/W2112309389","https://openalex.org/W2116419577","https://openalex.org/W2118846320","https://openalex.org/W2122241182","https://openalex.org/W2122462682","https://openalex.org/W2127632638","https://openalex.org/W2135068186","https://openalex.org/W2144000554","https://openalex.org/W2148924453","https://openalex.org/W2148953326","https://openalex.org/W2149576310","https://openalex.org/W2154094201","https://openalex.org/W2157828778","https://openalex.org/W2158970840","https://openalex.org/W2159955334","https://openalex.org/W2161533677","https://openalex.org/W2167890215","https://openalex.org/W2171423579","https://openalex.org/W2259041632","https://openalex.org/W2992503005"],"related_works":["https://openalex.org/W2033548502","https://openalex.org/W2086535669","https://openalex.org/W2073938229","https://openalex.org/W2075453095","https://openalex.org/W2132552227","https://openalex.org/W6990742360","https://openalex.org/W3155954023","https://openalex.org/W4206315356","https://openalex.org/W2159955334","https://openalex.org/W2351970665"],"abstract_inverted_index":{"We":[0],"investigated":[1],"the":[2,5,16,20,26,43,81,87,96,123,128,155,164,169,178,201],"changes":[3],"in":[4,42,140,187,206],"serum":[6,165,181,202],"levels":[7,91,137,148,167,183],"of":[8,23,28,45,47,89,95,105,180,204],"tumor":[9],"necrosis":[10],"factor":[11],"(TNF)-\u03b1":[12],"and":[13,19,70,127,143,168,184],"interleukin":[14],"(IL)-6,":[15],"pro-inflammatory":[17],"cytokines,":[18],"possible":[21],"effect":[22,198],"melatonin":[24,73],"on":[25],"modulation":[27],"these":[29],"inflammatory":[30],"molecules":[31],"after":[32,102,172,190],"renal":[33,67,71,78,141,173,188,191,207],"ischemia":[34],"reperfusion":[35,106],"(IR).":[36],"The":[37,98],"study":[38],"was":[39,113,120,130,159],"carried":[40],"out":[41],"laboratory":[44],"Department":[46],"Pharmacology.":[48],"Forty-six":[49],"male":[50],"Wistar":[51],"albino":[52],"rats":[53,99],"were":[54,84,100,149],"divided":[55],"into":[56],"five":[57],"groups":[58],"as":[59],"control":[60,63,125,153],"(n=6),":[61],"positive":[62,124],"(n=4),":[64],"sham":[65],"(n=12),":[66,69],"IR":[68,72,116,142],"(n=12).":[74],"After":[75],"1":[76],"h":[77,104],"pedicle":[79],"occlusion,":[80],"blood":[82,129],"samples":[83],"taken":[85,131],"for":[86,107],"measurement":[88],"cytokine":[90],"at":[92,132],"second":[93],"hour":[94],"reperfusion.":[97],"sacrificed":[101],"24":[103],"histopathological":[108,170,185],"evaluation.":[109],"Melatonin":[110,175,193],"or":[111],"vehicle":[112],"administrated":[114],"to":[115,122],"rats.":[117],"Lipopolysaccharide":[118],"(LPS)":[119],"administered":[121],"group":[126],"fourth":[133],"hour.":[134],"Serum":[135,146],"TNF-\u03b1":[136,166,182,205],"increased":[138],"significantly":[139],"LPS":[144,156],"groups.":[145],"IL-6":[147],"not":[150],"different":[151],"from":[152],"except":[154],"group.":[157],"There":[158],"no":[160],"significant":[161],"correlation":[162],"between":[163],"score":[171],"IR.":[174,192,208],"treatment":[176],"reversed":[177],"increase":[179],"injury":[186],"tissue":[189],"may":[194],"have":[195],"a":[196],"protective":[197],"by":[199],"reducing":[200],"level":[203]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}