{"id":"https://openalex.org/W1984875486","doi":"https://doi.org/10.1016/s0898-6568(02)00112-2","title":"Molecular recognitions in the MAP kinase cascades","display_name":"Molecular recognitions in the MAP kinase cascades","publication_year":2003,"publication_date":"2003-03-25","ids":{"openalex":"https://openalex.org/W1984875486","doi":"https://doi.org/10.1016/s0898-6568(02)00112-2","mag":"1984875486","pmid":"https://pubmed.ncbi.nlm.nih.gov/12639708"},"language":"en","primary_location":{"id":"doi:10.1016/s0898-6568(02)00112-2","doi":"https://doi.org/10.1016/s0898-6568(02)00112-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0898-6568(02)00112-2","pdf_url":null,"source":{"id":"https://openalex.org/S113768434","display_name":"Cellular Signalling","issn_l":"0898-6568","issn":["0898-6568","1873-3913"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Signalling","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1984875486"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075498832","display_name":"Takuji Tanoue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takuji Tanoue","raw_affiliation_strings":["Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Sakyo, Kyoto 606-8502, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Sakyo, Kyoto 606-8502, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055112181","display_name":"Eisuke Nishida","orcid":"https://orcid.org/0000-0002-9225-0263","observed_orcids":["https://orcid.org/0000-0002-9225-0263"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Eisuke Nishida","raw_affiliation_strings":["Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Sakyo, Kyoto 606-8502, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Sakyo, Kyoto 606-8502, Japan","institution_ids":["https://openalex.org/I22299242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5055112181"],"corresponding_institution_ids":["https://openalex.org/I22299242"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":2.23,"has_fulltext":false,"cited_by_count":325,"citation_normalized_percentile":{"value":0.90562914,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"15","issue":"5","first_page":"455","last_page":"462"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.9185000061988831,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.9185000061988831,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.03959999978542328,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.029400000348687172,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitogen-activated-protein-kinase","display_name":"mitogen-activated protein kinase","score":0.8610000014305115},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.9070000052452087},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"signal transduction","score":0.7080000042915344},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.7549999952316284},{"id":"https://openalex.org/keywords/scaffolding","display_name":"scaffolding","score":0.8029999732971191}],"concepts":[{"id":"https://openalex.org/C53645450","wikidata":"https://www.wikidata.org/wiki/Q907093","display_name":"Scaffold protein","level":3,"score":0.7810267806053162},{"id":"https://openalex.org/C57074206","wikidata":"https://www.wikidata.org/wiki/Q14197552","display_name":"MAPK/ERK pathway","level":3,"score":0.7038527131080627},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.6867884993553162},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6769603490829468},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.5444101691246033},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.5351579785346985},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5270143747329712},{"id":"https://openalex.org/C132149769","wikidata":"https://www.wikidata.org/wiki/Q899651","display_name":"Mitogen-activated protein kinase","level":3,"score":0.483708918094635},{"id":"https://openalex.org/C2909378205","wikidata":"https://www.wikidata.org/wiki/Q899651","display_name":"MAPK cascade","level":4,"score":0.43572917580604553},{"id":"https://openalex.org/C50929876","wikidata":"https://www.wikidata.org/wiki/Q164280","display_name":"Subfamily","level":3,"score":0.42822685837745667},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.399469792842865},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38882356882095337},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3453482389450073},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3419676423072815},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08146461844444275},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010749","descriptor_name":"Phosphoprotein Phosphatases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010749","descriptor_name":"Phosphoprotein Phosphatases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017871","descriptor_name":"Calcium-Calmodulin-Dependent Protein Kinases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020928","descriptor_name":"Mitogen-Activated Protein Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020928","descriptor_name":"Mitogen-Activated Protein Kinases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D020935","descriptor_name":"MAP Kinase Signaling System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D048049","descriptor_name":"Extracellular Signal-Regulated MAP Kinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0898-6568(02)00112-2","doi":"https://doi.org/10.1016/s0898-6568(02)00112-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0898-6568(02)00112-2","pdf_url":null,"source":{"id":"https://openalex.org/S113768434","display_name":"Cellular Signalling","issn_l":"0898-6568","issn":["0898-6568","1873-3913"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Signalling","raw_type":"journal-article"},{"id":"pmid:12639708","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12639708","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular signalling","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":88,"referenced_works":["https://openalex.org/W1560650269","https://openalex.org/W1606273823","https://openalex.org/W1766090917","https://openalex.org/W1857538073","https://openalex.org/W1899552864","https://openalex.org/W1928407971","https://openalex.org/W1967218150","https://openalex.org/W1968189883","https://openalex.org/W1973473002","https://openalex.org/W1976417846","https://openalex.org/W1980028299","https://openalex.org/W1980514336","https://openalex.org/W1982186905","https://openalex.org/W1985065252","https://openalex.org/W1986229370","https://openalex.org/W1993657069","https://openalex.org/W1994351845","https://openalex.org/W1994954884","https://openalex.org/W1995035611","https://openalex.org/W1995819749","https://openalex.org/W1996405087","https://openalex.org/W1999377902","https://openalex.org/W1999813498","https://openalex.org/W2002303369","https://openalex.org/W2004629227","https://openalex.org/W2007559737","https://openalex.org/W2009556803","https://openalex.org/W2012571494","https://openalex.org/W2014761974","https://openalex.org/W2016606027","https://openalex.org/W2017012572","https://openalex.org/W2018221682","https://openalex.org/W2022840078","https://openalex.org/W2027649846","https://openalex.org/W2031889181","https://openalex.org/W2035743526","https://openalex.org/W2041798139","https://openalex.org/W2042629507","https://openalex.org/W2045929031","https://openalex.org/W2047604907","https://openalex.org/W2052578867","https://openalex.org/W2056178963","https://openalex.org/W2056823054","https://openalex.org/W2059986458","https://openalex.org/W2061699263","https://openalex.org/W2065477683","https://openalex.org/W2068248480","https://openalex.org/W2068583506","https://openalex.org/W2068633079","https://openalex.org/W2072243374","https://openalex.org/W2075104267","https://openalex.org/W2076485183","https://openalex.org/W2083076387","https://openalex.org/W2083117403","https://openalex.org/W2084766033","https://openalex.org/W2085931606","https://openalex.org/W2087609448","https://openalex.org/W2089959253","https://openalex.org/W2093621392","https://openalex.org/W2093958609","https://openalex.org/W2095152292","https://openalex.org/W2096910934","https://openalex.org/W2097783992","https://openalex.org/W2099267053","https://openalex.org/W2100774604","https://openalex.org/W2101704246","https://openalex.org/W2103381809","https://openalex.org/W2105298978","https://openalex.org/W2110845720","https://openalex.org/W2110911902","https://openalex.org/W2111222398","https://openalex.org/W2111252945","https://openalex.org/W2116669977","https://openalex.org/W2118457425","https://openalex.org/W2119670701","https://openalex.org/W2120781124","https://openalex.org/W2122057254","https://openalex.org/W2140490890","https://openalex.org/W2140851951","https://openalex.org/W2147103035","https://openalex.org/W2152589434","https://openalex.org/W2155483393","https://openalex.org/W2164063328","https://openalex.org/W2170723584","https://openalex.org/W2337225223","https://openalex.org/W2614496215","https://openalex.org/W4230279981","https://openalex.org/W4239714346"],"related_works":["https://openalex.org/W1992023215","https://openalex.org/W2132752670","https://openalex.org/W1970071313","https://openalex.org/W2948738732","https://openalex.org/W2053383702","https://openalex.org/W2083117403","https://openalex.org/W1988154515","https://openalex.org/W2018507205","https://openalex.org/W2155158959","https://openalex.org/W4411273560"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":17}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}