{"id":"https://openalex.org/W1984641925","doi":"https://doi.org/10.1186/1471-2180-13-245","title":"Carbapenem-resistant Acinetobacter baumannii from Brazil: role of carO alleles expression and blaOXA-23 gene","display_name":"Carbapenem-resistant Acinetobacter baumannii from Brazil: role of carO alleles expression and blaOXA-23 gene","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W1984641925","doi":"https://doi.org/10.1186/1471-2180-13-245","mag":"1984641925","pmid":"https://pubmed.ncbi.nlm.nih.gov/24195496","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4228306"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2180-13-245","doi":"https://doi.org/10.1186/1471-2180-13-245","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2180-13-245","pdf_url":"https://bmcmicrobiol.biomedcentral.com/counter/pdf/10.1186/1471-2180-13-245","source":{"id":"https://openalex.org/S128543880","display_name":"BMC Microbiology","issn_l":"1471-2180","issn":["1471-2180"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcmicrobiol.biomedcentral.com/counter/pdf/10.1186/1471-2180-13-245","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102844322","display_name":"\u00c9rica Louren\u00e7o da Fonseca","orcid":"https://orcid.org/0000-0002-5029-7389","observed_orcids":["https://orcid.org/0000-0002-5029-7389"]},"institutions":[{"id":"https://openalex.org/I4405286966","display_name":"Instituto Oswaldo Cruz","ror":"https://ror.org/03pww0c55","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286966","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Erica Fonseca","raw_affiliation_strings":["Laborat\u00f3rio de Gen\u00e9tica Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil. ericafon@ioc.fiocruz.br","Laborat\u00f3rio de Gen\u00e9tica Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Gen\u00e9tica Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil. ericafon@ioc.fiocruz.br","institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"]},{"raw_affiliation_string":"Laborat\u00f3rio de Gen\u00e9tica Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108202779","display_name":"\u00c9rica Miranda Damasio Scheidegger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405286966","display_name":"Instituto Oswaldo Cruz","ror":"https://ror.org/03pww0c55","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286966","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Erica Scheidegger","raw_affiliation_strings":["Laborat\u00f3rio de Gen\u00e9tica Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Gen\u00e9tica Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113675543","display_name":"Fernanda S. Freitas","orcid":"https://orcid.org/0000-0003-2621-5723","observed_orcids":["https://orcid.org/0000-0003-2621-5723"]},"institutions":[{"id":"https://openalex.org/I4405286966","display_name":"Instituto Oswaldo Cruz","ror":"https://ror.org/03pww0c55","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286966","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Fernanda S Freitas","raw_affiliation_strings":["Laborat\u00f3rio de Gen\u00e9tica Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Gen\u00e9tica Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111063926","display_name":"Ros\u00e2ngela Cipriano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47327664","display_name":"Universidade Federal do Maranh\u00e3o","ror":"https://ror.org/043fhe951","country_code":"BR","type":"education","lineage":["https://openalex.org/I47327664"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ros\u00e2ngela Cipriano","raw_affiliation_strings":["Departamento de Medicina 1, Universidade Federal do Maranh\u00e3o, S\u00e3o Lu\u00eds, Maranh\u00e3o, Brazil","Departamento de Medicina 1, Universidade Federal do Maranh\u00e3o, S\u00e3o Lu\u00eds, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Medicina 1, Universidade Federal do Maranh\u00e3o, S\u00e3o Lu\u00eds, Maranh\u00e3o, Brazil","institution_ids":["https://openalex.org/I47327664"]},{"raw_affiliation_string":"Departamento de Medicina 1, Universidade Federal do Maranh\u00e3o, S\u00e3o Lu\u00eds, Brazil","institution_ids":["https://openalex.org/I47327664"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103829000","display_name":"Ana Carolina Paulo Vicente","orcid":"https://orcid.org/0000-0001-7086-2042","observed_orcids":["https://orcid.org/0000-0001-7086-2042"]},"institutions":[{"id":"https://openalex.org/I4405286966","display_name":"Instituto Oswaldo Cruz","ror":"https://ror.org/03pww0c55","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286966","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ana Carolina P Vicente","raw_affiliation_strings":["Laborat\u00f3rio de Gen\u00e9tica Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Gen\u00e9tica Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5102844322"],"corresponding_institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":2.801,"has_fulltext":true,"cited_by_count":61,"citation_normalized_percentile":{"value":0.89009434,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"13","issue":"1","first_page":"245","last_page":"245"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acinetobacter-baumannii","display_name":"Acinetobacter baumannii","score":0.9980000257492065},{"id":"https://openalex.org/keywords/carbapenem-resistance","display_name":"carbapenem resistance","score":1.0},{"id":"https://openalex.org/keywords/oxa-23-carbapenemase","display_name":"OXA-23 carbapenemase","score":0.8740000128746033},{"id":"https://openalex.org/keywords/blaoxa-51","display_name":"blaOXA-51","score":0.8149999976158142},{"id":"https://openalex.org/keywords/isaba1","display_name":"ISAba1","score":0.925000011920929},{"id":"https://openalex.org/keywords/imipenem-resistance","display_name":"imipenem resistance","score":0.9330000281333923},{"id":"https://openalex.org/keywords/carbapenemase-production","display_name":"carbapenemase production","score":0.6589999794960022},{"id":"https://openalex.org/keywords/porin-expression","display_name":"porin expression","score":0.6420000195503235},{"id":"https://openalex.org/keywords/antibiotic-resistance-mechanisms","display_name":"antibiotic resistance mechanisms","score":0.6470000147819519}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8252058625221252},{"id":"https://openalex.org/C2776315533","wikidata":"https://www.wikidata.org/wiki/Q3241189","display_name":"Acinetobacter baumannii","level":4,"score":0.7926020622253418},{"id":"https://openalex.org/C2779631663","wikidata":"https://www.wikidata.org/wiki/Q425152","display_name":"Imipenem","level":4,"score":0.7507187724113464},{"id":"https://openalex.org/C2776685102","wikidata":"https://www.wikidata.org/wiki/Q410897","display_name":"Carbapenem","level":3,"score":0.6788292527198792},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5815799832344055},{"id":"https://openalex.org/C2779259085","wikidata":"https://www.wikidata.org/wiki/Q418946","display_name":"Colistin","level":3,"score":0.5677538514137268},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5035886168479919},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.48172882199287415},{"id":"https://openalex.org/C2777317804","wikidata":"https://www.wikidata.org/wiki/Q67101192","display_name":"Porin","level":5,"score":0.464506596326828},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4162624180316925},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.3864282965660095},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.2813371419906616},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.24649563431739807},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.24028614163398743},{"id":"https://openalex.org/C146587185","wikidata":"https://www.wikidata.org/wiki/Q258248","display_name":"Bacterial outer membrane","level":4,"score":0.19314351677894592},{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.12721869349479675}],"mesh":[{"descriptor_ui":"D000151","descriptor_name":"Acinetobacter Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001425","descriptor_name":"Bacterial Outer Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001425","descriptor_name":"Bacterial Outer Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001618","descriptor_name":"beta-Lactamases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001938","descriptor_name":"Brazil","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015780","descriptor_name":"Carbapenems","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016521","descriptor_name":"Electrophoresis, Gel, Pulsed-Field","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018272","descriptor_name":"Porins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018272","descriptor_name":"Porins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018440","descriptor_name":"beta-Lactam Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040981","descriptor_name":"Acinetobacter baumannii","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D040981","descriptor_name":"Acinetobacter baumannii","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D040981","descriptor_name":"Acinetobacter baumannii","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D040981","descriptor_name":"Acinetobacter baumannii","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D058889","descriptor_name":"Molecular Typing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1186/1471-2180-13-245","doi":"https://doi.org/10.1186/1471-2180-13-245","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2180-13-245","pdf_url":"https://bmcmicrobiol.biomedcentral.com/counter/pdf/10.1186/1471-2180-13-245","source":{"id":"https://openalex.org/S128543880","display_name":"BMC Microbiology","issn_l":"1471-2180","issn":["1471-2180"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Microbiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3197829","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4228306","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:24195496","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24195496","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4228306","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4228306/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Microbiol","raw_type":"Text"},{"id":"pmh:oai:www.arca.fiocruz.br:icict/11801","doi":null,"is_oa":true,"landing_page_url":"https://www.arca.fiocruz.br/handle/icict/11801","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da FIOCRUZ (ARCA)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:americanae.aecid.es:2316652","doi":null,"is_oa":true,"landing_page_url":"https://www.arca.fiocruz.br/handle/icict/11801","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da FIOCRUZ (ARCA)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:arca.fiocruz.br:icict/11801","doi":null,"is_oa":true,"landing_page_url":"https://arca.fiocruz.br/handle/icict/11801","pdf_url":null,"source":{"id":"https://openalex.org/S7407055450","display_name":"Arca - Reposit\u00f3rio Institucional da Fiocruz","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"mag:2468240145","doi":null,"is_oa":false,"landing_page_url":"https://link.springer.com/content/pdf/10.1186%2F1471-2180-13-245.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1186/1471-2180-13-245","doi":"https://doi.org/10.1186/1471-2180-13-245","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2180-13-245","pdf_url":"https://bmcmicrobiol.biomedcentral.com/counter/pdf/10.1186/1471-2180-13-245","source":{"id":"https://openalex.org/S128543880","display_name":"BMC Microbiology","issn_l":"1471-2180","issn":["1471-2180"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320322749","display_name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","ror":"https://ror.org/03kk0s825"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1984641925.pdf","grobid_xml":"https://content.openalex.org/works/W1984641925.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1920890130","https://openalex.org/W1955612312","https://openalex.org/W1998380709","https://openalex.org/W2037335929","https://openalex.org/W2057618717","https://openalex.org/W2082877515","https://openalex.org/W2083748261","https://openalex.org/W2093644984","https://openalex.org/W2105161608","https://openalex.org/W2115486016","https://openalex.org/W2121097797","https://openalex.org/W2126750975","https://openalex.org/W2136700350","https://openalex.org/W2149018580","https://openalex.org/W2160185557","https://openalex.org/W2169499475","https://openalex.org/W2171239126","https://openalex.org/W2326651935","https://openalex.org/W2743041357","https://openalex.org/W3022232404"],"related_works":["https://openalex.org/W2468240145","https://openalex.org/W2363389590","https://openalex.org/W2375023407","https://openalex.org/W2461838221","https://openalex.org/W2379774533","https://openalex.org/W2769113404","https://openalex.org/W2365466250","https://openalex.org/W4408886042","https://openalex.org/W7096626801","https://openalex.org/W2384652171"],"abstract_inverted_index":{"BACKGROUND:":[0],"Carbapenems":[1],"are":[2,108],"the":[3,33,51,68,71,79,82,94,135,138,144,156,188,218,231,235,245],"antibiotics":[4],"of":[5,24,35,54,81,90,125,137,147,158,202,237,248],"choice":[6],"to":[7,16,195,216],"treat":[8],"infections":[9],"caused":[10],"by":[11,22],"Acinetobacter":[12],"baumannii,":[13],"and":[14,27,58,76,121,143,151,161,165,171,199,221,243],"resistance":[15,37,129,191,242],"this":[17,148,210,252],"class":[18],"can":[19],"be":[20],"determined":[21],"loss":[23,201],"membrane":[25],"permeability":[26],"enzymatic":[28],"mechanisms.":[29],"Here,":[30],"we":[31],"analyzed":[32],"basis":[34],"carbapenem":[36,190,241],"in":[38,60,85,152,182,209,233,240,251],"clinical":[39],"A.":[40],"baumannii":[41],"isolates":[42],"from":[43,117],"different":[44,238],"Brazilian":[45,186],"regions.":[46],"RESULTS:":[47],"The":[48,88,101,123],"analyses":[49,154],"addressed":[50],"carbapenemase":[52,95,109,197],"activity":[53,198],"OXA-23,":[55],"CarO":[56,163,203,249],"expression":[57,145,223],"alterations":[59],"its":[61],"primary":[62,139],"structure.":[63],"Susceptibility":[64],"test":[65,103],"revealed":[66,112,169],"that":[67,105,200],"strains":[69,91,107,116],"presented":[70],"COS":[72],"(Colistin-Only-Sensitive)":[73],"profile.":[74],"PCR":[75],"sequencing":[77],"showed":[78,155],"presence":[80],"chromosomally-encoded":[83],"blaOXA-51":[84],"all":[86],"isolates.":[87,177],"majority":[89],"(53%)":[92],"carried":[93],"blaOXA-23":[96],"gene":[97],"associated":[98],"with":[99,224],"ISAba1.":[100],"Hodge":[102],"indicated":[104],"these":[106,185,228],"producers.":[110],"PFGE":[111],"14":[113],"genotypes":[114],"among":[115,176],"Rio":[118],"de":[119],"Janeiro":[120],"Maranh\u00e3o.":[122],"influence":[124,247],"carO":[126,173,219],"on":[127],"imipenem":[128,225],"was":[130,193,214],"evaluated":[131],"considering":[132],"two":[133],"aspects:":[134],"composition":[136],"amino":[140],"acid":[141],"sequence;":[142],"level":[146],"porin.":[149],"Sequencing":[150],"silico":[153],"occurrence":[157],"CarOa,":[159],"CarOb":[160],"undefined":[162],"types,":[164],"Real":[166],"Time":[167],"RT-PCR":[168],"basal":[170],"reduced":[172],"transcription":[174],"levels":[175],"CONCLUSIONS:":[178],"We":[179],"concluded":[180],"that,":[181],"general,":[183],"for":[184],"isolates,":[187],"major":[189],"mechanism":[192],"due":[194],"OXA-23":[196],"porin":[204],"plays":[205],"a":[206],"minor":[207],"role":[208,236],"phenotype.":[211,253],"However,":[212],"it":[213],"possible":[215,246],"associate":[217],"alleles":[220],"their":[222],"resistance.":[226],"Therefore,":[227],"findings":[229],"underline":[230],"complexity":[232],"addressing":[234],"mechanisms":[239],"highlight":[244],"type":[250]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}