{"id":"https://openalex.org/W1983991435","doi":"https://doi.org/10.1016/s0022-3476(84)80304-2","title":"Isolated elevation of serum alkaline phosphatase","display_name":"Isolated elevation of serum alkaline phosphatase","publication_year":1984,"publication_date":"1984-11-01","ids":{"openalex":"https://openalex.org/W1983991435","doi":"https://doi.org/10.1016/s0022-3476(84)80304-2","mag":"1983991435","pmid":"https://pubmed.ncbi.nlm.nih.gov/6502308"},"language":"en","primary_location":{"id":"doi:10.1016/s0022-3476(84)80304-2","doi":"https://doi.org/10.1016/s0022-3476(84)80304-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0022-3476(84)80304-2","pdf_url":null,"source":{"id":"https://openalex.org/S3774022","display_name":"The Journal of Pediatrics","issn_l":"0022-3476","issn":["0022-3476","1085-8695","1097-6833"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pediatrics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084865295","display_name":"Gillian Lockitch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2802832906","display_name":"Vancouver General Hospital","ror":"https://ror.org/02zg69r60","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I141074466","https://openalex.org/I2799475292","https://openalex.org/I2802832906"]},{"id":"https://openalex.org/I4210153200","display_name":"BC Children's Hospital","ror":"https://ror.org/04n901w50","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210153200"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Gillian Lockitch","raw_affiliation_strings":["British Columbia's Children's Hospital Vancouver, British Columbia, Canada","Department of Pathology, University of British Columbia Vancouver, British Columbia, Canada","Vancouver General Hospital Vancouver, British Columbia, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"British Columbia's Children's Hospital Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I4210153200"]},{"raw_affiliation_string":"Department of Pathology, University of British Columbia Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"Vancouver General Hospital Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I2802832906"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035355762","display_name":"Morris R Pudek","orcid":"https://orcid.org/0000-0001-6432-263X","observed_orcids":["https://orcid.org/0000-0001-6432-263X"]},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2802832906","display_name":"Vancouver General Hospital","ror":"https://ror.org/02zg69r60","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I141074466","https://openalex.org/I2799475292","https://openalex.org/I2802832906"]},{"id":"https://openalex.org/I4210153200","display_name":"BC Children's Hospital","ror":"https://ror.org/04n901w50","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210153200"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M.R. Pudek","raw_affiliation_strings":["British Columbia's Children's Hospital Vancouver, British Columbia, Canada","Department of Pathology, University of British Columbia Vancouver, British Columbia, Canada","Vancouver General Hospital Vancouver, British Columbia, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"British Columbia's Children's Hospital Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I4210153200"]},{"raw_affiliation_string":"Department of Pathology, University of British Columbia Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"Vancouver General Hospital Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I2802832906"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007307249","display_name":"Anne Catherine Halstead","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I2802832906","display_name":"Vancouver General Hospital","ror":"https://ror.org/02zg69r60","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I141074466","https://openalex.org/I2799475292","https://openalex.org/I2802832906"]},{"id":"https://openalex.org/I4210153200","display_name":"BC Children's Hospital","ror":"https://ror.org/04n901w50","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210153200"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"A.C. Halstead","raw_affiliation_strings":["British Columbia's Children's Hospital Vancouver, British Columbia, Canada","Department of Pathology, University of British Columbia Vancouver, British Columbia, Canada","Vancouver General Hospital Vancouver, British Columbia, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"British Columbia's Children's Hospital Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I4210153200"]},{"raw_affiliation_string":"Department of Pathology, University of British Columbia Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"Vancouver General Hospital Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I2802832906"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5084865295"],"corresponding_institution_ids":["https://openalex.org/I141945490","https://openalex.org/I2802832906","https://openalex.org/I4210153200"],"apc_list":{"value":4570,"currency":"USD","value_usd":4570},"apc_paid":null,"fwci":1.5528,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.80302403,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"105","issue":"5","first_page":"773","last_page":"775"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13453","display_name":"Alkaline Phosphatase Research Studies","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13453","display_name":"Alkaline Phosphatase Research Studies","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12068","display_name":"Neonatal Health and Biochemistry","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/infants","display_name":"infants","score":0.4650000035762787},{"id":"https://openalex.org/keywords/clinical-characteristics","display_name":"clinical features","score":0.4320000112056732},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.48899999260902405}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8722769618034363},{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.7646853923797607},{"id":"https://openalex.org/C37054046","wikidata":"https://www.wikidata.org/wiki/Q641888","display_name":"Elevation (ballistics)","level":2,"score":0.4974344074726105},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4103330373764038},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24990642070770264},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.12632566690444946},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001847","descriptor_name":"Bone Diseases","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008107","descriptor_name":"Liver Diseases","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010001","descriptor_name":"Osteitis Deformans","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0022-3476(84)80304-2","doi":"https://doi.org/10.1016/s0022-3476(84)80304-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0022-3476(84)80304-2","pdf_url":null,"source":{"id":"https://openalex.org/S3774022","display_name":"The Journal of Pediatrics","issn_l":"0022-3476","issn":["0022-3476","1085-8695","1097-6833"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pediatrics","raw_type":"journal-article"},{"id":"pmid:6502308","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6502308","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of pediatrics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W135997456","https://openalex.org/W1911338543","https://openalex.org/W1993021157","https://openalex.org/W2004908718","https://openalex.org/W2007886105","https://openalex.org/W2026570478","https://openalex.org/W2043868853","https://openalex.org/W2051921722","https://openalex.org/W2119443977","https://openalex.org/W2145326600","https://openalex.org/W2149362818","https://openalex.org/W2398629398","https://openalex.org/W2442254736","https://openalex.org/W3001137629","https://openalex.org/W3001156667","https://openalex.org/W4230948051","https://openalex.org/W4301017694"],"related_works":["https://openalex.org/W2052179481","https://openalex.org/W2075325011","https://openalex.org/W7101052848","https://openalex.org/W3039195271","https://openalex.org/W780321267","https://openalex.org/W2425073573","https://openalex.org/W2418317440","https://openalex.org/W2399361762","https://openalex.org/W2004908718","https://openalex.org/W2398629398"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}