{"id":"https://openalex.org/W1983671987","doi":"https://doi.org/10.1248/bpb.33.1063","title":"Idesolide, an Isolate of Idesia polycarpa, Inhibits Apoptosis through Induction of Intracellular Heat Shock Protein 70 in C2C12 Muscle Cells","display_name":"Idesolide, an Isolate of Idesia polycarpa, Inhibits Apoptosis through Induction of Intracellular Heat Shock Protein 70 in C2C12 Muscle Cells","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W1983671987","doi":"https://doi.org/10.1248/bpb.33.1063","mag":"1983671987","pmid":"https://pubmed.ncbi.nlm.nih.gov/20522979"},"language":"en","primary_location":{"id":"doi:10.1248/bpb.33.1063","doi":"https://doi.org/10.1248/bpb.33.1063","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.33.1063","pdf_url":"https://www.jstage.jst.go.jp/article/bpb/33/6/33_6_1063/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/bpb/33/6/33_6_1063/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Min-Ho Jung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Min-Ho Jung","raw_affiliation_strings":["Division of Biological Science and Technology, College of Science and Technology, Institute of Biomaterials, Yonsei University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biological Science and Technology, College of Science and Technology, Institute of Biomaterials, Yonsei University","institution_ids":["https://openalex.org/I193775966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005685871","display_name":"Jungmin Yoo","orcid":"https://orcid.org/0000-0003-2275-7656","observed_orcids":["https://orcid.org/0000-0003-2275-7656"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jung-Min Yoo","raw_affiliation_strings":["Division of Biological Science and Technology, College of Science and Technology, Institute of Biomaterials, Yonsei University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biological Science and Technology, College of Science and Technology, Institute of Biomaterials, Yonsei University","institution_ids":["https://openalex.org/I193775966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111570878","display_name":"Yeo-Jin Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yeo-Jin Kang","raw_affiliation_strings":["Division of Biological Science and Technology, College of Science and Technology, Institute of Biomaterials, Yonsei University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biological Science and Technology, College of Science and Technology, Institute of Biomaterials, Yonsei University","institution_ids":["https://openalex.org/I193775966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023541905","display_name":"Hyoung Woo Lee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hyoung Woo Lee","raw_affiliation_strings":["Institute for Life Science, Elcomscience Co., Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Life Science, Elcomscience Co., Ltd","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100454615","display_name":"Seung Hyun Kim","orcid":"https://orcid.org/0000-0001-9644-9598","observed_orcids":["https://orcid.org/0000-0001-9644-9598","https://orcid.org/0000-0001-8269-2036","https://orcid.org/0000-0003-2723-6489"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seung Hyun Kim","raw_affiliation_strings":["Institute for Life Science, Elcomscience Co., Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Life Science, Elcomscience Co., Ltd","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087561050","display_name":"Sang Hyun Sung","orcid":"https://orcid.org/0000-0002-0527-4815","observed_orcids":["https://orcid.org/0000-0002-0527-4815"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang Hyun Sung","raw_affiliation_strings":["College of Pharmacy, Seoul National University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Seoul National University","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101114888","display_name":"Yong-Jin Lee","orcid":"https://orcid.org/0009-0000-1888-7322","observed_orcids":["https://orcid.org/0009-0000-1888-7322"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yong-Jin Lee","raw_affiliation_strings":["Chuncheon Bioindustry Foundation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chuncheon Bioindustry Foundation","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078717180","display_name":"Inho Choi","orcid":"https://orcid.org/0000-0002-0884-5994","observed_orcids":["https://orcid.org/0000-0002-0884-5994"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Inho Choi","raw_affiliation_strings":["Division of Biological Science and Technology, College of Science and Technology, Institute of Biomaterials, Yonsei University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biological Science and Technology, College of Science and Technology, Institute of Biomaterials, Yonsei University","institution_ids":["https://openalex.org/I193775966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062324757","display_name":"Tack\u2010Joong Kim","orcid":"https://orcid.org/0000-0002-1697-3232","observed_orcids":["https://orcid.org/0000-0002-1697-3232"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Tack-Joong Kim","raw_affiliation_strings":["Division of Biological Science and Technology, College of Science and Technology, Institute of Biomaterials, Yonsei University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biological Science and Technology, College of Science and Technology, Institute of Biomaterials, Yonsei University","institution_ids":["https://openalex.org/I193775966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5205,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.57132849,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"33","issue":"6","first_page":"1063","last_page":"1066"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.5723000168800354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.5723000168800354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.4235999882221222,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/idesia-polycarpa","display_name":"Idesia polycarpa","score":1.0},{"id":"https://openalex.org/keywords/hsp70","display_name":"HSP70","score":0.9919999837875366},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8240000009536743},{"id":"https://openalex.org/keywords/skeletal-muscle-atrophy","display_name":"skeletal muscle atrophy","score":0.8489999771118164},{"id":"https://openalex.org/keywords/c2c12-muscle-cells","display_name":"C2C12 muscle cells","score":0.859000027179718},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.949999988079071},{"id":"https://openalex.org/keywords/hydrogen-peroxide","display_name":"hydrogen peroxide","score":0.8949999809265137},{"id":"https://openalex.org/keywords/disuse-muscle-atrophy","display_name":"disuse atrophy","score":0.6679999828338623},{"id":"https://openalex.org/keywords/muscular-dystrophy","display_name":"muscular dystrophy","score":0.6140000224113464},{"id":"https://openalex.org/keywords/natural-products","display_name":"natural products","score":0.5139999985694885}],"concepts":[{"id":"https://openalex.org/C60278653","wikidata":"https://www.wikidata.org/wiki/Q5008075","display_name":"C2C12","level":4,"score":0.812524139881134},{"id":"https://openalex.org/C205260736","wikidata":"https://www.wikidata.org/wiki/Q418939","display_name":"Heat shock protein","level":3,"score":0.7735780477523804},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.6696056127548218},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6519508361816406},{"id":"https://openalex.org/C68991219","wikidata":"https://www.wikidata.org/wiki/Q419102","display_name":"Hsp70","level":4,"score":0.5335759520530701},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5307763814926147},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5238920450210571},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.5204089879989624},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2959195375442505},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20509260892868042},{"id":"https://openalex.org/C3763915","wikidata":"https://www.wikidata.org/wiki/Q3331437","display_name":"Myogenesis","level":3,"score":0.18541786074638367},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1146714985370636}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008517","descriptor_name":"Phytotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009133","descriptor_name":"Muscular Atrophy","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D013141","descriptor_name":"Spiro Compounds","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013141","descriptor_name":"Spiro Compounds","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018840","descriptor_name":"HSP70 Heat-Shock Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D031308","descriptor_name":"Salicaceae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D032342","descriptor_name":"Muscle Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1248/bpb.33.1063","doi":"https://doi.org/10.1248/bpb.33.1063","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.33.1063","pdf_url":"https://www.jstage.jst.go.jp/article/bpb/33/6/33_6_1063/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},{"id":"pmid:20522979","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20522979","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological & pharmaceutical bulletin","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1248/bpb.33.1063","doi":"https://doi.org/10.1248/bpb.33.1063","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.33.1063","pdf_url":"https://www.jstage.jst.go.jp/article/bpb/33/6/33_6_1063/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"},{"id":"https://openalex.org/F4320322349","display_name":"Ministry of Education, Science and Technology","ror":"https://ror.org/01p262204"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1983671987.pdf","grobid_xml":"https://content.openalex.org/works/W1983671987.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W162515504","https://openalex.org/W346872721","https://openalex.org/W1598830628","https://openalex.org/W1773902424","https://openalex.org/W1830780748","https://openalex.org/W1974473484","https://openalex.org/W1986721293","https://openalex.org/W1991865867","https://openalex.org/W2004782459","https://openalex.org/W2007501972","https://openalex.org/W2011265783","https://openalex.org/W2013751209","https://openalex.org/W2018594065","https://openalex.org/W2027648530","https://openalex.org/W2032525800","https://openalex.org/W2034630481","https://openalex.org/W2045209051","https://openalex.org/W2046639009","https://openalex.org/W2049686361","https://openalex.org/W2054473882","https://openalex.org/W2061738083","https://openalex.org/W2084736894","https://openalex.org/W2085477560","https://openalex.org/W2090389306","https://openalex.org/W2111858669","https://openalex.org/W2145387039","https://openalex.org/W2155419259","https://openalex.org/W2161566587","https://openalex.org/W2170722828","https://openalex.org/W2280929046"],"related_works":["https://openalex.org/W1994955513","https://openalex.org/W2145396048","https://openalex.org/W2092826514","https://openalex.org/W2343930463","https://openalex.org/W338532611","https://openalex.org/W4386547454","https://openalex.org/W1981830493","https://openalex.org/W2363794007","https://openalex.org/W4398186558","https://openalex.org/W2170722828"],"abstract_inverted_index":{"Muscle":[0],"disorders,":[1],"such":[2],"as":[3],"muscular":[4,17],"dystrophy,":[5,18],"are":[6],"associated":[7],"with":[8,66],"an":[9],"increase":[10],"in":[11,20,50,77,102,119],"oxidative":[12,59],"stress.":[13],"Proposed":[14],"treatments":[15],"for":[16,68],"some":[19],"clinical":[21],"trials,":[22],"include":[23],"gene":[24],"therapy":[25],"and":[26,62,74],"muscle":[27,51,80,104,125],"cell":[28,72,96],"transplantation.":[29],"In":[30],"this":[31],"study,":[32],"we":[33],"investigated":[34],"the":[35,41,109,117],"effects":[36,57],"of":[37,43,100],"idesolide,":[38],"isolated":[39],"from":[40],"fruits":[42],"Idesia":[44],"polycarpa,":[45],"on":[46,58],"changes":[47],"that":[48,93,113,121],"occur":[49],"disuse":[52],"atrophy.":[53,126],"We":[54],"noted":[55],"protective":[56],"stress":[60],"response":[61],"HSP70":[63,88,101,120],"regulation.":[64],"Pre-treatment":[65],"idesolide":[67,83,94,114],"24":[69],"h":[70],"maintained":[71],"viability":[73],"decreased":[75],"apoptosis":[76],"H(2)O(2)-treated":[78],"C(2)C(12)":[79,103],"cells.":[81,105],"The":[82],"pretreatment":[84],"also":[85],"increased":[86],"intracellular":[87],"protein.":[89],"Our":[90],"results":[91],"suggest":[92],"inhibits":[95],"death":[97],"through":[98],"induction":[99],"This":[106],"work":[107],"is":[108],"first":[110],"to":[111],"report":[112],"can":[115],"regulate":[116],"decrease":[118],"occurs":[122],"during":[123],"skeletal":[124]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}