{"id":"https://openalex.org/W1983548824","doi":"https://doi.org/10.1074/jbc.273.24.14690","title":"Structure, Synthesis, and Molecular Cloning of Dermaseptins B, a Family of Skin Peptide Antibiotics","display_name":"Structure, Synthesis, and Molecular Cloning of Dermaseptins B, a Family of Skin Peptide Antibiotics","publication_year":1998,"publication_date":"1998-06-01","ids":{"openalex":"https://openalex.org/W1983548824","doi":"https://doi.org/10.1074/jbc.273.24.14690","mag":"1983548824","pmid":"https://pubmed.ncbi.nlm.nih.gov/9614066"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.273.24.14690","doi":"https://doi.org/10.1074/jbc.273.24.14690","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.273.24.14690","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.273.24.14690","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"St\u00e9phane Charpentier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"St\u00e9phane Charpentier","raw_affiliation_strings":["Laboratoire de Bioactivation des Peptides, Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Bioactivation des Peptides, Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France","institution_ids":["https://openalex.org/I4210113761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074878501","display_name":"Mohamed Amiche","orcid":"https://orcid.org/0000-0001-9811-0635","observed_orcids":["https://orcid.org/0000-0001-9811-0635"]},"institutions":[{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mohamed Amiche","raw_affiliation_strings":["Laboratoire de Bioactivation des Peptides, Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Bioactivation des Peptides, Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France","institution_ids":["https://openalex.org/I4210113761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037557724","display_name":"J\u00e1n Me\u0161ter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4405276790","display_name":"Unit\u00e9 de Recherches sur les Peptides Neurodigestifs et le Diab\u00e8te","ror":"https://ror.org/00ag6p996","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405276790"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jan Mester","raw_affiliation_strings":["INSERM U 55, 184 rue du Faubourg Saint-Antoine 75571 Paris Cedex 12, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U 55, 184 rue du Faubourg Saint-Antoine 75571 Paris Cedex 12, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4405276790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007003645","display_name":"V\u00e9ronique Vouille","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"V\u00e9ronique Vouille","raw_affiliation_strings":["Laboratoire de Bioactivation des Peptides, Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Bioactivation des Peptides, Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France","institution_ids":["https://openalex.org/I4210113761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075513391","display_name":"Jean\u2010Pierre Le Ca\u00ebr","orcid":"https://orcid.org/0000-0002-9668-4747","observed_orcids":["https://orcid.org/0000-0002-9668-4747"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I98910050","display_name":"ESPCI Paris","ror":"https://ror.org/03zx86w41","country_code":"FR","type":"education","lineage":["https://openalex.org/I190752583","https://openalex.org/I2746051580","https://openalex.org/I98910050"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Pierre Le Caer","raw_affiliation_strings":["Laboratoire de Neurobiologie et Diversite\u0301 Cellulaire, CNRS URA 2054, ESPCI, 10 rue Vauquelin 75231 Paris Cedex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Neurobiologie et Diversite\u0301 Cellulaire, CNRS URA 2054, ESPCI, 10 rue Vauquelin 75231 Paris Cedex 05, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I98910050"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086683190","display_name":"Pierre Nicolas","orcid":"https://orcid.org/0000-0002-1133-0609","observed_orcids":["https://orcid.org/0000-0002-1133-0609"]},"institutions":[{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pierre Nicolas","raw_affiliation_strings":["Laboratoire de Bioactivation des Peptides, Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Bioactivation des Peptides, Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France","institution_ids":["https://openalex.org/I4210113761"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042674789","display_name":"Antoine Delfour","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113761","display_name":"Institut Jacques Monod","ror":"https://ror.org/02c5gc203","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210113761"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Antoine Delfour","raw_affiliation_strings":["Laboratoire de Bioactivation des Peptides, Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Bioactivation des Peptides, Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France","institution_ids":["https://openalex.org/I4210113761"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5042674789"],"corresponding_institution_ids":["https://openalex.org/I4210113761"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":4.094,"has_fulltext":false,"cited_by_count":111,"citation_normalized_percentile":{"value":0.94065105,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"273","issue":"24","first_page":"14690","last_page":"14697"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11353","display_name":"Venomous Animal Envenomation and Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dermaseptins","display_name":"dermaseptins","score":0.8920000195503235},{"id":"https://openalex.org/keywords/phyllomedusa-bicolor","display_name":"Phyllomedusa bicolor","score":0.925000011920929},{"id":"https://openalex.org/keywords/frog-skin-secretions","display_name":"frog skin secretions","score":0.8209999799728394},{"id":"https://openalex.org/keywords/antimicrobial-peptides","display_name":"antimicrobial peptides","score":0.9259999990463257},{"id":"https://openalex.org/keywords/alpha-helical-peptides","display_name":"alpha-helical peptides","score":0.8289999961853027},{"id":"https://openalex.org/keywords/signal-peptide","display_name":"signal peptide","score":0.7300000190734863},{"id":"https://openalex.org/keywords/gene-cloning","display_name":"gene cloning","score":0.7680000066757202},{"id":"https://openalex.org/keywords/gene-structure","display_name":"gene structure","score":0.6480000019073486},{"id":"https://openalex.org/keywords/gene-evolution","display_name":"gene evolution","score":0.6179999709129333},{"id":"https://openalex.org/keywords/polycationic-peptides","display_name":"polycationic peptides","score":0.7609999775886536}],"concepts":[{"id":"https://openalex.org/C121050878","wikidata":"https://www.wikidata.org/wiki/Q5135020","display_name":"Cloning (programming)","level":2,"score":0.7055009603500366},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.6396105289459229},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.5941201448440552},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3992600440979004},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39055347442626953},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3627645969390869},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3491250276565552},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.32500168681144714},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19826194643974304},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1234828531742096},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.056914687156677246}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001001","descriptor_name":"Anura","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011498","descriptor_name":"Protein Precursors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017421","descriptor_name":"Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021382","descriptor_name":"Protein Sorting Signals","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D023181","descriptor_name":"Antimicrobial Cationic Peptides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D029845","descriptor_name":"Amphibian Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1074/jbc.273.24.14690","doi":"https://doi.org/10.1074/jbc.273.24.14690","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.273.24.14690","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:9614066","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9614066","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-02160836v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-02160836","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Biological Chemistry, 1998, 273 (24), pp.14690-14697. ⟨10.1074/jbc.273.24.14690⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1074/jbc.273.24.14690","doi":"https://doi.org/10.1074/jbc.273.24.14690","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.273.24.14690","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W587418765","https://openalex.org/W1482180296","https://openalex.org/W1492811993","https://openalex.org/W1547691854","https://openalex.org/W1597233068","https://openalex.org/W1603880431","https://openalex.org/W1934068236","https://openalex.org/W1967284752","https://openalex.org/W1977221227","https://openalex.org/W1978036864","https://openalex.org/W1981014117","https://openalex.org/W1981263096","https://openalex.org/W1986616865","https://openalex.org/W1987339118","https://openalex.org/W1988039633","https://openalex.org/W1996289330","https://openalex.org/W1996652558","https://openalex.org/W1998206952","https://openalex.org/W1998671550","https://openalex.org/W2004775545","https://openalex.org/W2009221323","https://openalex.org/W2018190671","https://openalex.org/W2020465942","https://openalex.org/W2042096080","https://openalex.org/W2061179713","https://openalex.org/W2072933784","https://openalex.org/W2079372854","https://openalex.org/W2084318337","https://openalex.org/W2085929853","https://openalex.org/W2089320192","https://openalex.org/W2128305979","https://openalex.org/W2130974803","https://openalex.org/W2134812217","https://openalex.org/W2138270253","https://openalex.org/W2144634347","https://openalex.org/W2168519444","https://openalex.org/W2279926712","https://openalex.org/W2314225431","https://openalex.org/W2600349519","https://openalex.org/W2601913882","https://openalex.org/W4255020332"],"related_works":["https://openalex.org/W1547691854","https://openalex.org/W1492811993","https://openalex.org/W1998400934","https://openalex.org/W2074271012","https://openalex.org/W2140993651","https://openalex.org/W654653095","https://openalex.org/W1619954790","https://openalex.org/W2036034982","https://openalex.org/W2766221882","https://openalex.org/W1967284752"],"abstract_inverted_index":{"Analysis":[0],"of":[1,11,70,85,93,103,119,143,154],"antimicrobial":[2,113],"activities":[3,140],"that":[4,130,146],"are":[5,74],"present":[6],"in":[7],"the":[8,12,66,71,81,86,100,117,147],"skin":[9,118],"secretions":[10],"South":[13],"American":[14],"frog":[15,122],"Phyllomedusa":[16],"bicolor":[17],"revealed":[18],"six":[19],"polycationic":[20],"(lysine-rich)":[21],"and":[22,56,141],"amphipathic":[23],"alpha-helical":[24],"peptides,":[25],"24-33":[26],"residues":[27,69],"long,":[28],"termed":[29],"dermaseptins":[30],"B1":[31],"to":[32],"B6,":[33],"respectively.":[34],"Prepro-dermaseptins":[35],"B":[36,95],"all":[37],"contain":[38],"an":[39],"almost":[40],"identical":[41],"signal":[42,54,63],"peptide,":[43],"which":[44],"is":[45],"followed":[46],"by":[47,76,80],"a":[48,52,57,155],"conserved":[49,77,156],"acidic":[50,72],"propiece,":[51],"processing":[53],"Lys-Arg,":[55],"dermaseptin":[58,87],"progenitor":[59],"sequence.":[60],"The":[61,89,124],"22-residue":[62],"peptide":[64],"plus":[65],"first":[67,82],"3":[68],"propiece":[73],"encoded":[75],"nucleotides":[78],"encompassed":[79],"coding":[83],"exon":[84],"genes.":[88],"25-residue":[90],"amino-terminal":[91],"region":[92,102],"prepro-dermaseptins":[94],"shares":[96],"50%":[97],"identity":[98],"with":[99,134],"corresponding":[101,148],"precursors":[104],"for":[105,112],"D-amino":[106],"acid":[107],"containing":[108],"opioid":[109],"peptides":[110,114],"or":[111],"originating":[115],"from":[116],"distantly":[120],"related":[121],"species.":[123],"remarkable":[125],"similarity":[126],"found":[127],"between":[128],"prepro-proteins":[129],"encode":[131],"end":[132],"products":[133],"strikingly":[135],"different":[136],"sequences,":[137],"conformations,":[138],"biological":[139],"modes":[142],"action":[144],"suggests":[145],"genes":[149],"have":[150],"evolved":[151],"through":[152],"dissemination":[153],"\"secretory":[157],"cassette\"":[158],"exon.":[159]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}