{"id":"https://openalex.org/W1983543097","doi":null,"title":"Childhood vulvar lichen sclerosus. The course after puberty.","display_name":"Childhood vulvar lichen sclerosus. The course after puberty.","publication_year":2002,"publication_date":"2002-09-01","ids":{"openalex":"https://openalex.org/W1983543097","mag":"1983543097","pmid":"https://pubmed.ncbi.nlm.nih.gov/12380449"},"language":"en","primary_location":{"id":"pmid:12380449","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12380449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of reproductive medicine","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103410547","display_name":"Jenny Powell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802742124","display_name":"John Radcliffe Hospital","ror":"https://ror.org/0080acb59","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802742124","https://openalex.org/I4210127145","https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jenny Powell","raw_affiliation_strings":["Department of Dermatology, Radcliffe Hospitals, Oxford, United Kingdom. jjphbp@aol.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Radcliffe Hospitals, Oxford, United Kingdom. jjphbp@aol.com","institution_ids":["https://openalex.org/I2802742124"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033907428","display_name":"Fenella Wojnarowska","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fenella Wojnarowska","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.1482,"has_fulltext":false,"cited_by_count":97,"citation_normalized_percentile":{"value":0.95026375,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"47","issue":"9","first_page":"706","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11713","display_name":"Genital Health and Disease","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11713","display_name":"Genital Health and Disease","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12866","display_name":"Urologic and reproductive health conditions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vulvar-lichen-sclerosus","display_name":"vulvar lichen sclerosus","score":0.9660000205039978},{"id":"https://openalex.org/keywords/puberty","display_name":"puberty","score":0.6880000233650208},{"id":"https://openalex.org/keywords/clinical-course","display_name":"clinical course","score":0.7509999871253967},{"id":"https://openalex.org/keywords/vulvar-squamous-cell-carcinoma","display_name":"vulvar squamous cell carcinoma","score":0.7549999952316284},{"id":"https://openalex.org/keywords/pruritus","display_name":"pruritus","score":0.8040000200271606},{"id":"https://openalex.org/keywords/topical-corticosteroids","display_name":"topical corticosteroids","score":0.8560000061988831},{"id":"https://openalex.org/keywords/long-term-follow-up","display_name":"long-term follow-up","score":0.8859999775886536},{"id":"https://openalex.org/keywords/pediatric-vulvar-disease","display_name":"pediatric vulvar disease","score":0.6100000143051147},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.7950000166893005}],"concepts":[{"id":"https://openalex.org/C2776552008","wikidata":"https://www.wikidata.org/wiki/Q1641400","display_name":"Lichen sclerosus","level":2,"score":0.9377378225326538},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.879162073135376},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.6020220518112183},{"id":"https://openalex.org/C527108885","wikidata":"https://www.wikidata.org/wiki/Q835153","display_name":"Physical examination","level":2,"score":0.5632888078689575},{"id":"https://openalex.org/C2909580181","wikidata":"https://www.wikidata.org/wiki/Q1908194","display_name":"Vulvar Carcinoma","level":3,"score":0.5305816531181335},{"id":"https://openalex.org/C2776016352","wikidata":"https://www.wikidata.org/wiki/Q873072","display_name":"Clitoris","level":2,"score":0.5285704731941223},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5135657787322998},{"id":"https://openalex.org/C2911206564","wikidata":"https://www.wikidata.org/wiki/Q2192288","display_name":"Vulvar Diseases","level":3,"score":0.5021915435791016},{"id":"https://openalex.org/C2776316342","wikidata":"https://www.wikidata.org/wiki/Q2192288","display_name":"Vulva","level":2,"score":0.4979245662689209},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.44663235545158386},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4322826862335205},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3223743140697479},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.27217546105384827},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21633973717689514}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011627","descriptor_name":"Puberty","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014845","descriptor_name":"Vulvar Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D014845","descriptor_name":"Vulvar Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014845","descriptor_name":"Vulvar Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018459","descriptor_name":"Lichen Sclerosus et Atrophicus","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D018459","descriptor_name":"Lichen Sclerosus et Atrophicus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018459","descriptor_name":"Lichen Sclerosus et Atrophicus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:12380449","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12380449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of reproductive medicine","raw_type":"Journal Article"},{"id":"mag:1983543097","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12380449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2168915319","https://openalex.org/W7159797272","https://openalex.org/W2113469920","https://openalex.org/W4362458844","https://openalex.org/W2058815252","https://openalex.org/W4293217210","https://openalex.org/W4404960032","https://openalex.org/W3152224601","https://openalex.org/W4415173097","https://openalex.org/W2969874808"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"identify":[2],"girls":[3,25,33],"with":[4,34,61,127,142,156,165,201],"vulvar":[5,42,143,169,204],"lichen":[6],"sclerosus":[7],"(LS)":[8],"and":[9,38,51,166,192],"to":[10],"follow":[11],"them":[12],"through":[13],"puberty,":[14,163],"documenting":[15],"the":[16,19,72,97,120,194,211],"course":[17],"of":[18,31,45,58,67,119,152,168,203,213],"disease.":[20],"STUDY":[21],"DESIGN:":[22],"Twenty-one":[23],"postpubertal":[24,74],"were":[26,54],"identified":[27],"from":[28],"a":[29,40,154],"cohort":[30],"75":[32],"LS":[35,62,68,158,180],"presenting":[36],"prepubertally":[37],"attending":[39],"pediatric":[41],"clinic.":[43],"Details":[44],"current":[46],"symptoms,":[47,81],"findings":[48],"on":[49],"examination":[50],"treatment":[52],"needs":[53],"recorded.":[55],"A":[56],"database":[57],"263":[59],"women":[60,126,197],"was":[63],"reviewed":[64],"for":[65],"onset":[66],"premenarche.":[69],"RESULTS:":[70],"Of":[71,123,136],"21":[73],"girls,":[75],"16":[76,110],"reported":[77],"an":[78],"improvement":[79],"in":[80,102,109,113,134,149,159,196],"but":[82,184],"11":[83],"stated":[84],"that":[85,179,193],"they":[86],"still":[87],"experienced":[88],"occasional":[89],"pruritus,":[90],"requiring":[91],"intermittent":[92],"topical":[93],"steroid":[94],"application.":[95],"Although":[96],"disorder":[98],"appeared":[99],"less":[100],"active":[101],"most":[103],"cases,":[104],"definite":[105],"physical":[106,117],"signs":[107,118],"persisted":[108],"patients":[111,115,141],"(75%);":[112],"5":[114,130],"no":[116],"disease":[121,195],"remained.":[122],"251":[124],"postmenopausal":[125],"LS,":[128,144],"<":[129],"could":[131,146],"recall":[132,147],"symptoms":[133,148],"childhood.":[135,150],"12":[137],"young":[138],"adult":[139],"premenopausal":[140],"4":[145],"One":[151],"these,":[153],"32-year-old":[155],"well-documented":[157],"childhood":[160],"resolving":[161],"at":[162,190],"presented":[164],"died":[167],"squamous":[170],"cell":[171],"carcinoma":[172],"(SCC).":[173],"CONCLUSION:":[174],"Patients":[175],"should":[176,209],"be":[177,199,210],"aware":[178],"may":[181,198],"improve":[182],"symptomatically":[183],"usually":[185],"does":[186],"not":[187],"entirely":[188],"resolve":[189],"puberty":[191],"associated":[200],"development":[202],"SCC.":[205],"Ideally,":[206],"long-term":[207],"follow-up":[208],"standard":[212],"care.":[214]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}