{"id":"https://openalex.org/W1983523988","doi":"https://doi.org/10.1055/s-2007-986688","title":"Oxidative Stress Is Associated with Clinical Severity of Nausea and Vomiting of Pregnancy","display_name":"Oxidative Stress Is Associated with Clinical Severity of Nausea and Vomiting of Pregnancy","publication_year":2007,"publication_date":"2007-09-01","ids":{"openalex":"https://openalex.org/W1983523988","doi":"https://doi.org/10.1055/s-2007-986688","mag":"1983523988","pmid":"https://pubmed.ncbi.nlm.nih.gov/17893839"},"language":"en","primary_location":{"id":"doi:10.1055/s-2007-986688","doi":"https://doi.org/10.1055/s-2007-986688","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2007-986688","pdf_url":null,"source":{"id":"https://openalex.org/S82239980","display_name":"American Journal of Perinatology","issn_l":"0735-1631","issn":["0735-1631","1098-8785"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Perinatology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090539676","display_name":"Fatma Ferda Verit","orcid":"https://orcid.org/0000-0002-7104-4532","observed_orcids":["https://orcid.org/0000-0002-7104-4532","https://orcid.org/0000-0002-9902-9350"]},"institutions":[{"id":"https://openalex.org/I80538482","display_name":"Harran University","ror":"https://ror.org/057qfs197","country_code":"TR","type":"education","lineage":["https://openalex.org/I80538482"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Fatma Verit","raw_affiliation_strings":["Department of Obstetrics and Gynaecology, Harran University Faculty of Medicine, Sanliurfa, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynaecology, Harran University Faculty of Medicine, Sanliurfa, Turkey","institution_ids":["https://openalex.org/I80538482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012778283","display_name":"\u00d6zcan Erel","orcid":"https://orcid.org/0000-0002-2996-3236","observed_orcids":["https://orcid.org/0000-0002-2996-3236"]},"institutions":[{"id":"https://openalex.org/I80538482","display_name":"Harran University","ror":"https://ror.org/057qfs197","country_code":"TR","type":"education","lineage":["https://openalex.org/I80538482"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ozcan Erel","raw_affiliation_strings":["Department of Clinical Biochemistry, Harran University Faculty of Medicine, Sanliurfa, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Biochemistry, Harran University Faculty of Medicine, Sanliurfa, Turkey","institution_ids":["https://openalex.org/I80538482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057989815","display_name":"Mehmet Sav","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80538482","display_name":"Harran University","ror":"https://ror.org/057qfs197","country_code":"TR","type":"education","lineage":["https://openalex.org/I80538482"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mehmet Sav","raw_affiliation_strings":["Department of Obstetrics and Gynaecology, Harran University Faculty of Medicine, Sanliurfa, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynaecology, Harran University Faculty of Medicine, Sanliurfa, Turkey","institution_ids":["https://openalex.org/I80538482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012574673","display_name":"Necla \u00c7elik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80538482","display_name":"Harran University","ror":"https://ror.org/057qfs197","country_code":"TR","type":"education","lineage":["https://openalex.org/I80538482"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Necla Celik","raw_affiliation_strings":["Department of Clinical Biochemistry, Harran University Faculty of Medicine, Sanliurfa, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Biochemistry, Harran University Faculty of Medicine, Sanliurfa, Turkey","institution_ids":["https://openalex.org/I80538482"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039860768","display_name":"Dursun \u00c7ADIRCI","orcid":"https://orcid.org/0000-0003-0969-382X","observed_orcids":["https://orcid.org/0000-0003-0969-382X"]},"institutions":[{"id":"https://openalex.org/I80538482","display_name":"Harran University","ror":"https://ror.org/057qfs197","country_code":"TR","type":"education","lineage":["https://openalex.org/I80538482"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Dursun Cadirci","raw_affiliation_strings":["Department of Family Medicine, Harran University Faculty of Medicine, Sanliurfa, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Family Medicine, Harran University Faculty of Medicine, Sanliurfa, Turkey","institution_ids":["https://openalex.org/I80538482"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I80538482"],"apc_list":null,"apc_paid":null,"fwci":0.686,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.74331457,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"24","issue":"9","first_page":"545","last_page":"548"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.6509000062942505,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.6509000062942505,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.14030000567436218,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.12380000203847885,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nausea-and-vomiting-of-pregnancy","display_name":"nausea and vomiting of pregnancy","score":0.9789999723434448},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9950000047683716},{"id":"https://openalex.org/keywords/total-oxidant-status","display_name":"total oxidant status","score":0.9929999709129333},{"id":"https://openalex.org/keywords/total-antioxidant-status","display_name":"total antioxidant status","score":0.968999981880188},{"id":"https://openalex.org/keywords/clinical-severity","display_name":"clinical severity","score":0.7200000286102295},{"id":"https://openalex.org/keywords/plasma-biomarkers","display_name":"plasma biomarkers","score":0.5519999861717224},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9136670827865601},{"id":"https://openalex.org/C2780580376","wikidata":"https://www.wikidata.org/wiki/Q186889","display_name":"Nausea","level":2,"score":0.8520164489746094},{"id":"https://openalex.org/C2780852908","wikidata":"https://www.wikidata.org/wiki/Q127076","display_name":"Vomiting","level":2,"score":0.7863883972167969},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.7540497779846191},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.7137216329574585},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6646684408187866},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5944691896438599},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5344699025154114},{"id":"https://openalex.org/C2993539680","wikidata":"https://www.wikidata.org/wiki/Q902552","display_name":"Antioxidant capacity","level":3,"score":0.4972977936267853},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.47385767102241516},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009325","descriptor_name":"Nausea","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009325","descriptor_name":"Nausea","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014839","descriptor_name":"Vomiting","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014839","descriptor_name":"Vomiting","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D014839","descriptor_name":"Vomiting","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016877","descriptor_name":"Oxidants","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D017665","descriptor_name":"Hydroxyl Radical","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1055/s-2007-986688","doi":"https://doi.org/10.1055/s-2007-986688","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2007-986688","pdf_url":null,"source":{"id":"https://openalex.org/S82239980","display_name":"American Journal of Perinatology","issn_l":"0735-1631","issn":["0735-1631","1098-8785"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Perinatology","raw_type":"journal-article"},{"id":"pmid:17893839","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17893839","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of perinatology","raw_type":"Journal Article"},{"id":"pmh:a69f76f1-bc24-4d64-83aa-dc1aba2657d8","doi":null,"is_oa":false,"landing_page_url":"https://avesis.aybu.edu.tr/publication/details/a69f76f1-bc24-4d64-83aa-dc1aba2657d8/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055213","display_name":"AYBU AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2040146935","https://openalex.org/W2466912510","https://openalex.org/W2122394845","https://openalex.org/W132192245","https://openalex.org/W4362506201","https://openalex.org/W2033669353","https://openalex.org/W3208265945","https://openalex.org/W2103158420","https://openalex.org/W2793331779","https://openalex.org/W2242307094"],"abstract_inverted_index":{"Our":[0],"objective":[1],"was":[2,82,100,105,180],"(1)":[3],"to":[4,31],"evaluate":[5],"total":[6,11],"oxidant":[7],"status":[8,13],"(TOS)":[9],"and":[10,19,29,39,49,69,91,103,127,158,187,202,213],"antioxidant":[12],"(TAS)":[14],"in":[15,56,108,177,210],"women":[16,46,53,64,71,109,134],"with":[17,25,47,74,110,135,150,161],"nausea":[18],"vomiting":[20],"of":[21,42,79,89,125,130,191,200,216],"pregnancy":[22],"(NVP)":[23],"compared":[24],"healthy":[26,51],"pregnant":[27,52],"controls,":[28],"(2)":[30],"explore":[32],"any":[33],"possible":[34],"relationship":[35,183],"between":[36,184],"oxidative":[37,173,185],"stress":[38,174,186],"clinical":[40,189,214],"severity":[41,78,190,215],"the":[43,57,80,133,188,192,198,211],"disease.":[44,193],"Fifty-three":[45],"NVP":[48,111,120,137],"35":[50],"were":[54,65,72,93],"enrolled":[55],"study.":[58],"Of":[59],"these":[60],"53":[61],"women,":[62],"25":[63],"classified":[66,73],"as":[67,207],"mild":[68,136],"28":[70],"moderate/severe":[75,119],"NVP.":[76,178,217],"The":[77,118],"disease":[81],"assessed":[83],"by":[84,95],"Rhodes'":[85,145],"index.":[86],"Plasma":[87],"levels":[88,124,129,199],"TOS":[90,99,126,151,201],"TAS":[92,104,131,162,203],"determined":[94],"using":[96],"automated":[97],"methods.":[98],"significantly":[101,106],"higher":[102,123],"lower":[107,128],"(":[112,138],"P":[113,139,155,166],"<":[114,140,156,167],"0.0001,":[115,141],"for":[116,142],"both).":[117,143],"group":[121],"had":[122],"than":[132],"Moreover,":[144],"index":[146],"showed":[147],"positive":[148],"correlation":[149,160],"(r":[152,163],"=":[153,164],"0.563;":[154],"0.0001)":[157],"negative":[159],"-0.595;":[165],"0.0001).":[168],"These":[169],"findings":[170],"indicate":[171],"that":[172,197],"is":[175],"increased":[176],"There":[179],"a":[181],"strong":[182],"Therefore,":[194],"we":[195],"suggest":[196],"can":[204],"be":[205],"used":[206],"additional":[208],"markers":[209],"diagnosis":[212]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}