{"id":"https://openalex.org/W1983451616","doi":"https://doi.org/10.1016/s0034-5687(99)00071-7","title":"Effects of gas density on experimentally obstructed ventilation during acute hypoxia","display_name":"Effects of gas density on experimentally obstructed ventilation during acute hypoxia","publication_year":1999,"publication_date":"1999-09-01","ids":{"openalex":"https://openalex.org/W1983451616","doi":"https://doi.org/10.1016/s0034-5687(99)00071-7","mag":"1983451616","pmid":"https://pubmed.ncbi.nlm.nih.gov/10563443"},"language":"en","primary_location":{"id":"doi:10.1016/s0034-5687(99)00071-7","doi":"https://doi.org/10.1016/s0034-5687(99)00071-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0034-5687(99)00071-7","pdf_url":null,"source":{"id":"https://openalex.org/S45421690","display_name":"Respiration Physiology","issn_l":"0034-5687","issn":["0034-5687","1872-7611"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiration Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111922830","display_name":"Jack A. Loeppky","orcid":"https://orcid.org/0000-0003-1634-3000","observed_orcids":["https://orcid.org/0000-0003-1634-3000"]},"institutions":[{"id":"https://openalex.org/I1305258596","display_name":"Lovelace Respiratory Research Institute","ror":"https://ror.org/038qbqz41","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1305258596"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jack A. Loeppky","raw_affiliation_strings":["Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA. jloeppky@lrri.org","Lovelace Respiratory Research Institute, Albuquerque, NM, 87108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA. jloeppky@lrri.org","institution_ids":["https://openalex.org/I1305258596"]},{"raw_affiliation_string":"Lovelace Respiratory Research Institute, Albuquerque, NM, 87108, USA","institution_ids":["https://openalex.org/I1305258596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073754189","display_name":"Dean O. Kuethe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1305258596","display_name":"Lovelace Respiratory Research Institute","ror":"https://ror.org/038qbqz41","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1305258596"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dean O. Kuethe","raw_affiliation_strings":["Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA","institution_ids":["https://openalex.org/I1305258596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110652149","display_name":"Stephen A. Altobelli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098276","display_name":"New Mexico Resonance","ror":"https://ror.org/00w9zab79","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210098276"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen A. Altobelli","raw_affiliation_strings":["New Mexico Resonance, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New Mexico Resonance, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA","institution_ids":["https://openalex.org/I4210098276"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041421575","display_name":"Pietro Scotto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36443711","display_name":"Magna Graecia University","ror":"https://ror.org/0530bdk91","country_code":"IT","type":"education","lineage":["https://openalex.org/I36443711"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Pietro Scotto","raw_affiliation_strings":["Fisiologia Umana, University of Catanzaro, I-88100 Catanzaro, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fisiologia Umana, University of Catanzaro, I-88100 Catanzaro, Italy","institution_ids":["https://openalex.org/I36443711"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062413270","display_name":"Johannes Piiper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137682","display_name":"Max Planck Institute of Experimental Medicine","ror":"https://ror.org/04a7f6w43","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210137682","https://openalex.org/I4387154714"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Johannes Piiper","raw_affiliation_strings":["Max Planck Institute of Experimental Medicine, Hermann-Rein-Str 3, Goettingen D-37075, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Planck Institute of Experimental Medicine, Hermann-Rein-Str 3, Goettingen D-37075, Germany","institution_ids":["https://openalex.org/I4210137682"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5111922830"],"corresponding_institution_ids":["https://openalex.org/I1305258596"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.16003639,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"117","issue":"2-3","first_page":"151","last_page":"160"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.4302000105381012,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.4302000105381012,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.29249998927116394,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.23659999668598175,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/helium-oxygen-mixture","display_name":"helium-oxygen mixture","score":0.9210000038146973},{"id":"https://openalex.org/keywords/gas-density","display_name":"gas density","score":0.7590000033378601},{"id":"https://openalex.org/keywords/acute-hypoxia","display_name":"acute hypoxia","score":0.9190000295639038},{"id":"https://openalex.org/keywords/airway-resistance","display_name":"airway resistance","score":0.7879999876022339},{"id":"https://openalex.org/keywords/arterial-pco2","display_name":"arterial PCO2","score":0.675000011920929},{"id":"https://openalex.org/keywords/alveolar-ventilation","display_name":"alveolar ventilation","score":0.8169999718666077},{"id":"https://openalex.org/keywords/tidal-volume","display_name":"tidal volume","score":0.7009999752044678},{"id":"https://openalex.org/keywords/breathing-pattern","display_name":"breathing pattern","score":0.8289999961853027},{"id":"https://openalex.org/keywords/metabolic-rate","display_name":"metabolic rate","score":0.8679999709129333},{"id":"https://openalex.org/keywords/gas-exchange","display_name":"gas exchange","score":0.8880000114440918},{"id":"https://openalex.org/keywords/emphysema","display_name":"emphysema","score":0.800000011920929},{"id":"https://openalex.org/keywords/hyperpnea","display_name":"hyperpnea","score":0.3490000069141388}],"concepts":[{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.7212756276130676},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.5286339521408081},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.49927306175231934},{"id":"https://openalex.org/C182215343","wikidata":"https://www.wikidata.org/wiki/Q472287","display_name":"Respiration","level":2,"score":0.49909496307373047},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3880671262741089},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3112856149673462},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.17359310388565063},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.166331946849823},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08089414238929749},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.060586124658584595},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000388","descriptor_name":"Air","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000402","descriptor_name":"Airway Obstruction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D000403","descriptor_name":"Airway Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006371","descriptor_name":"Helium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008173","descriptor_name":"Lung Diseases, Obstructive","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008173","descriptor_name":"Lung Diseases, Obstructive","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009584","descriptor_name":"Nitrogen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011650","descriptor_name":"Pulmonary Alveoli","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012119","descriptor_name":"Respiration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012123","descriptor_name":"Pulmonary Ventilation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013046","descriptor_name":"Specific Gravity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0034-5687(99)00071-7","doi":"https://doi.org/10.1016/s0034-5687(99)00071-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0034-5687(99)00071-7","pdf_url":null,"source":{"id":"https://openalex.org/S45421690","display_name":"Respiration Physiology","issn_l":"0034-5687","issn":["0034-5687","1872-7611"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiration Physiology","raw_type":"journal-article"},{"id":"pmid:10563443","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10563443","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiration physiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W39250998","https://openalex.org/W591260783","https://openalex.org/W1824314566","https://openalex.org/W1948995489","https://openalex.org/W1968015217","https://openalex.org/W1979409390","https://openalex.org/W2000884763","https://openalex.org/W2008643330","https://openalex.org/W2009908181","https://openalex.org/W2029197193","https://openalex.org/W2030675022","https://openalex.org/W2041216436","https://openalex.org/W2043400069","https://openalex.org/W2043471834","https://openalex.org/W2050583639","https://openalex.org/W2053135450","https://openalex.org/W2076422538","https://openalex.org/W2079631644","https://openalex.org/W2107311678","https://openalex.org/W2132398337","https://openalex.org/W2173456905","https://openalex.org/W2222009244","https://openalex.org/W2222746323","https://openalex.org/W2231971014","https://openalex.org/W2253868531","https://openalex.org/W2257110730","https://openalex.org/W2265279814","https://openalex.org/W2274729311","https://openalex.org/W2327170645","https://openalex.org/W2328724723","https://openalex.org/W2399214746","https://openalex.org/W2417453263","https://openalex.org/W2474944756","https://openalex.org/W2612054593","https://openalex.org/W2780031792"],"related_works":["https://openalex.org/W2055914164","https://openalex.org/W2059104167","https://openalex.org/W2413383827","https://openalex.org/W2069129914","https://openalex.org/W2047310750","https://openalex.org/W2119094838","https://openalex.org/W2043471834","https://openalex.org/W2394815357","https://openalex.org/W2002475054","https://openalex.org/W1985292754"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}