{"id":"https://openalex.org/W1983417536","doi":"https://doi.org/10.3109/13685530903406789","title":"Sildenafilversuscontinuous positive airway pressure for erectile dysfunction in men with obstructive sleep apnea: a meta-analysis","display_name":"Sildenafilversuscontinuous positive airway pressure for erectile dysfunction in men with obstructive sleep apnea: a meta-analysis","publication_year":2009,"publication_date":"2009-12-10","ids":{"openalex":"https://openalex.org/W1983417536","doi":"https://doi.org/10.3109/13685530903406789","mag":"1983417536","pmid":"https://pubmed.ncbi.nlm.nih.gov/20001468"},"language":"en","primary_location":{"id":"doi:10.3109/13685530903406789","doi":"https://doi.org/10.3109/13685530903406789","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13685530903406789","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685530903406789?needAccess=true&role=button","source":{"id":"https://openalex.org/S172622653","display_name":"The Aging Male","issn_l":"1368-5538","issn":["1368-5538","1473-0790"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Male","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685530903406789?needAccess=true&role=button","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100452129","display_name":"Xiaoming Li","orcid":"https://orcid.org/0000-0002-5555-9034","observed_orcids":["https://orcid.org/0000-0002-5555-9034"]},"institutions":[{"id":"https://openalex.org/I4210124531","display_name":"Lanzhou University Second Hospital","ror":"https://ror.org/02erhaz63","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124531"]},{"id":"https://openalex.org/I76214153","display_name":"Lanzhou University","ror":"https://ror.org/01mkqqe32","country_code":"CN","type":"education","lineage":["https://openalex.org/I76214153"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoming Li","raw_affiliation_strings":["Institute of Urology, Second Hospital, Lanzhou University, Gansu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Urology, Second Hospital, Lanzhou University, Gansu, China","institution_ids":["https://openalex.org/I4210124531","https://openalex.org/I76214153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018343826","display_name":"Zhilong Dong","orcid":"https://orcid.org/0000-0002-4919-8164","observed_orcids":["https://orcid.org/0000-0002-4919-8164"]},"institutions":[{"id":"https://openalex.org/I4210124531","display_name":"Lanzhou University Second Hospital","ror":"https://ror.org/02erhaz63","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124531"]},{"id":"https://openalex.org/I76214153","display_name":"Lanzhou University","ror":"https://ror.org/01mkqqe32","country_code":"CN","type":"education","lineage":["https://openalex.org/I76214153"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhilong Dong","raw_affiliation_strings":["Institute of Urology, Second Hospital, Lanzhou University, Lanzhou, Gansu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Urology, Second Hospital, Lanzhou University, Lanzhou, Gansu, China","institution_ids":["https://openalex.org/I4210124531","https://openalex.org/I76214153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019927724","display_name":"Yixin Wan","orcid":"https://orcid.org/0000-0003-3858-0971","observed_orcids":["https://orcid.org/0000-0003-3858-0971"]},"institutions":[{"id":"https://openalex.org/I4210124531","display_name":"Lanzhou University Second Hospital","ror":"https://ror.org/02erhaz63","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124531"]},{"id":"https://openalex.org/I76214153","display_name":"Lanzhou University","ror":"https://ror.org/01mkqqe32","country_code":"CN","type":"education","lineage":["https://openalex.org/I76214153"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yixin Wan","raw_affiliation_strings":["Institute of Pneumology, Second Hospital, Lanzhou University, Lanzhou, Gansu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pneumology, Second Hospital, Lanzhou University, Lanzhou, Gansu, China","institution_ids":["https://openalex.org/I4210124531","https://openalex.org/I76214153"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100387995","display_name":"Zhiping Wang","orcid":"https://orcid.org/0000-0002-8140-591X","observed_orcids":["https://orcid.org/0000-0002-8140-591X","https://orcid.org/0000-0002-6438-1418","https://orcid.org/0009-0004-9890-9809","https://orcid.org/0000-0002-2367-0491"]},"institutions":[{"id":"https://openalex.org/I4210124531","display_name":"Lanzhou University Second Hospital","ror":"https://ror.org/02erhaz63","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124531"]},{"id":"https://openalex.org/I76214153","display_name":"Lanzhou University","ror":"https://ror.org/01mkqqe32","country_code":"CN","type":"education","lineage":["https://openalex.org/I76214153"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhiping Wang","raw_affiliation_strings":["Institute of Urology, Second Hospital, Lanzhou University, Lanzhou, Gansu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Urology, Second Hospital, Lanzhou University, Lanzhou, Gansu, China","institution_ids":["https://openalex.org/I4210124531","https://openalex.org/I76214153"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100387995"],"corresponding_institution_ids":["https://openalex.org/I4210124531","https://openalex.org/I76214153"],"apc_list":{"value":2085,"currency":"GBP","value_usd":2557},"apc_paid":null,"fwci":0.1678,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.17264082,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"13","issue":"2","first_page":"82","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sildenafil","display_name":"sildenafil","score":0.7680000066757202},{"id":"https://openalex.org/keywords/continuous-positive-airway-pressure","display_name":"continuous positive airway pressure","score":0.9879999756813049},{"id":"https://openalex.org/keywords/erectile-dysfunction","display_name":"erectile dysfunction","score":0.996999979019165},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":1.0},{"id":"https://openalex.org/keywords/erectile-function","display_name":"erectile function","score":0.6549999713897705},{"id":"https://openalex.org/keywords/treatment-satisfaction","display_name":"treatment satisfaction","score":0.7089999914169312},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.5550000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9661939144134521},{"id":"https://openalex.org/C2779929075","wikidata":"https://www.wikidata.org/wiki/Q184674","display_name":"Erectile dysfunction","level":2,"score":0.8725013732910156},{"id":"https://openalex.org/C2776768464","wikidata":"https://www.wikidata.org/wiki/Q191521","display_name":"Sildenafil","level":2,"score":0.8583617210388184},{"id":"https://openalex.org/C2779547634","wikidata":"https://www.wikidata.org/wiki/Q5165502","display_name":"Continuous positive airway pressure","level":3,"score":0.7073835730552673},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.6743829250335693},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6639662384986877},{"id":"https://openalex.org/C3020768380","wikidata":"https://www.wikidata.org/wiki/Q133993","display_name":"Erectile function","level":3,"score":0.6467539668083191},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.5897654891014099},{"id":"https://openalex.org/C2777935920","wikidata":"https://www.wikidata.org/wiki/Q213600","display_name":"Sleep apnea","level":2,"score":0.4478083550930023},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.35872724652290344},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3236278295516968}],"mesh":[{"descriptor_ui":"D000068677","descriptor_name":"Sildenafil Citrate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007172","descriptor_name":"Erectile Dysfunction","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007172","descriptor_name":"Erectile Dysfunction","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D007172","descriptor_name":"Erectile Dysfunction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010410","descriptor_name":"Penile Erection","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010879","descriptor_name":"Piperazines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011687","descriptor_name":"Purines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D013450","descriptor_name":"Sulfones","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014665","descriptor_name":"Vasodilator Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016001","descriptor_name":"Confidence Intervals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017060","descriptor_name":"Patient Satisfaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D045422","descriptor_name":"Continuous Positive Airway Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.3109/13685530903406789","doi":"https://doi.org/10.3109/13685530903406789","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13685530903406789","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685530903406789?needAccess=true&role=button","source":{"id":"https://openalex.org/S172622653","display_name":"The Aging Male","issn_l":"1368-5538","issn":["1368-5538","1473-0790"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Male","raw_type":"journal-article"},{"id":"pmid:20001468","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20001468","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The aging male : the official journal of the International Society for the Study of the Aging Male","raw_type":"Journal Article"},{"id":"pmh:oai:ir.lzu.edu.cn/:262010/126015","doi":null,"is_oa":false,"landing_page_url":"http://ir.lzu.edu.cn/handle/262010/126015","pdf_url":null,"source":{"id":"https://openalex.org/S4406923049","display_name":"Lanzhou University Institutional Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.3109/13685530903406789","doi":"https://doi.org/10.3109/13685530903406789","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13685530903406789","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685530903406789?needAccess=true&role=button","source":{"id":"https://openalex.org/S172622653","display_name":"The Aging Male","issn_l":"1368-5538","issn":["1368-5538","1473-0790"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Male","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320313889","display_name":"Lanzhou University","ror":"https://ror.org/01mkqqe32"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1983417536.pdf","grobid_xml":"https://content.openalex.org/works/W1983417536.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W1791515516","https://openalex.org/W1977228997","https://openalex.org/W1978404312","https://openalex.org/W1981331898","https://openalex.org/W1983752874","https://openalex.org/W1987694108","https://openalex.org/W2000996919","https://openalex.org/W2005926500","https://openalex.org/W2007457237","https://openalex.org/W2018320285","https://openalex.org/W2030541107","https://openalex.org/W2034556696","https://openalex.org/W2035557978","https://openalex.org/W2075726900","https://openalex.org/W2084292135","https://openalex.org/W2085814883","https://openalex.org/W2108180331","https://openalex.org/W2113932992","https://openalex.org/W2118172610","https://openalex.org/W2139356364","https://openalex.org/W2297358297","https://openalex.org/W2333343699","https://openalex.org/W2335449614","https://openalex.org/W2785563066","https://openalex.org/W3022302886","https://openalex.org/W4243770305"],"related_works":["https://openalex.org/W2561819942","https://openalex.org/W1978404312","https://openalex.org/W1981331898","https://openalex.org/W2038101499","https://openalex.org/W2140747431","https://openalex.org/W4384693720","https://openalex.org/W1966514431","https://openalex.org/W4299990857","https://openalex.org/W1507036664","https://openalex.org/W2980029982"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"evaluate":[2],"the":[3,41,59,63,69,106,126,130,136,167,185],"effectiveness":[4,39],"of":[5,29,43,49,62,91,105,108,129,169,184],"sildenafil":[6,95,161],"versus":[7],"continuous":[8],"positive":[9],"airway":[10],"pressure":[11],"(CPAP)":[12],"for":[13,38,71,138],"patients":[14,64,80,93,131],"with":[15,68,135,173],"erectile":[16],"dysfunction":[17],"(ED)":[18],"and":[19,58,65,125,132,158],"obstructive":[20],"sleep":[21],"apnea":[22],"(OSA).":[23],"METHODS:":[24],"This":[25],"is":[26],"a":[27,30,97,182],"meta-analysis":[28],"randomized":[31,75],"controlled":[32,76],"trial.":[33],"The":[34],"main":[35],"outcome":[36],"measures":[37],"were":[40,81,156],"percentage":[42,107],"successful":[44,109],"intercourse":[45,110],"attempts,":[46],"International":[47],"Index":[48],"Erectile":[50],"Function":[51],"(IIEF)":[52],"domain":[53],"scores":[54,119],"(erectile":[55],"function,":[56],"EF)":[57],"satisfaction":[60,127],"levels":[61,128],"their":[66,133],"partners":[67,134],"treatment":[70,137,168],"ED.":[72],"RESULTS:":[73],"Two":[74],"trials":[77],"totaling":[78],"70":[79],"included.":[82],"Meta-analysis":[83],"results":[84],"are":[85],"as":[86],"follows:":[87],"after":[88],"12":[89],"weeks":[90],"treatment,":[92],"under":[94,101],"demonstrated":[96],"significant":[98],"advantage":[99],"over":[100],"CPAP":[102,165],"in":[103,166,171],"terms":[104],"attempts":[111],"[OR":[112,140],"=":[113,121,141],"3.24,":[114],"95%":[115,143],"CI":[116,144],"(2.37-4.43)],":[117],"EF":[118],"[WMD":[120],"3.57,":[122],"95%CI":[123],"(1.68-5.45)],":[124],"ED":[139,170],"3.56,":[142],"(1.27-9.98)].":[145],"CONCLUSION:":[146],"Current":[147],"clinical":[148],"studies":[149],"might":[150],"confirm":[151],"that":[152,177],"both":[153],"therapeutic":[154,179],"methods":[155,187],"safe":[157],"effective,":[159],"but":[160],"was":[162],"superior":[163],"to":[164],"men":[172],"OSA.":[174],"We":[175],"conclude":[176],"new":[178],"agents":[180],"or":[181],"combination":[183],"two":[186],"should":[188],"be":[189],"studied":[190],"further.":[191]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}