{"id":"https://openalex.org/W1983332016","doi":"https://doi.org/10.1071/rd12180","title":"Dynamic medium containing growth differentiation factor-9 and FSH maintains survival and promotes in vitro growth of caprine preantral follicles after long-term in vitro culture","display_name":"Dynamic medium containing growth differentiation factor-9 and FSH maintains survival and promotes in vitro growth of caprine preantral follicles after long-term in vitro culture","publication_year":2012,"publication_date":"2012-10-11","ids":{"openalex":"https://openalex.org/W1983332016","doi":"https://doi.org/10.1071/rd12180","mag":"1983332016","pmid":"https://pubmed.ncbi.nlm.nih.gov/23050662"},"language":"en","primary_location":{"id":"doi:10.1071/rd12180","doi":"https://doi.org/10.1071/rd12180","is_oa":false,"landing_page_url":"https://doi.org/10.1071/rd12180","pdf_url":null,"source":{"id":"https://openalex.org/S199941106","display_name":"Reproduction Fertility and Development","issn_l":"1031-3613","issn":["1031-3613","1448-5990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320302","host_organization_name":"CSIRO Publishing","host_organization_lineage":["https://openalex.org/P4310320302"],"host_organization_lineage_names":["CSIRO Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction, Fertility and Development","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029833161","display_name":"Anelise Maria Costa Vasconcelos Alves","orcid":"https://orcid.org/0000-0002-4020-9672","observed_orcids":["https://orcid.org/0000-0002-4020-9672"]},"institutions":[{"id":"https://openalex.org/I102939073","display_name":"Universidade Estadual do Cear\u00e1","ror":"https://ror.org/00sec1m50","country_code":"BR","type":"education","lineage":["https://openalex.org/I102939073"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"A. M. C. V. Alves","raw_affiliation_strings":["ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","ECorresponding author. Email: anelise_alves@yahoo.com.br","Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]},{"raw_affiliation_string":"ECorresponding author. Email: anelise_alves@yahoo.com.br","institution_ids":[]},{"raw_affiliation_string":"Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001858126","display_name":"Roberta Nogueira Chaves","orcid":"https://orcid.org/0000-0002-5367-0724","observed_orcids":["https://orcid.org/0000-0002-5367-0724"]},"institutions":[{"id":"https://openalex.org/I102939073","display_name":"Universidade Estadual do Cear\u00e1","ror":"https://ror.org/00sec1m50","country_code":"BR","type":"education","lineage":["https://openalex.org/I102939073"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"R. N. Chaves","raw_affiliation_strings":["ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]},{"raw_affiliation_string":"Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036432984","display_name":"Rebeca Magalh\u00e3es Pedrosa Rocha","orcid":"https://orcid.org/0000-0002-4991-3180","observed_orcids":["https://orcid.org/0000-0002-4991-3180"]},"institutions":[{"id":"https://openalex.org/I102939073","display_name":"Universidade Estadual do Cear\u00e1","ror":"https://ror.org/00sec1m50","country_code":"BR","type":"education","lineage":["https://openalex.org/I102939073"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"R. M. P. Rocha","raw_affiliation_strings":["ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]},{"raw_affiliation_string":"Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084602669","display_name":"Laritza Ferreira de Lima","orcid":"https://orcid.org/0000-0001-6391-7113","observed_orcids":["https://orcid.org/0000-0001-6391-7113"]},"institutions":[{"id":"https://openalex.org/I102939073","display_name":"Universidade Estadual do Cear\u00e1","ror":"https://ror.org/00sec1m50","country_code":"BR","type":"education","lineage":["https://openalex.org/I102939073"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"L. F. Lima","raw_affiliation_strings":["ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]},{"raw_affiliation_string":"Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]}]},{"author_position":"middle","author":{"id":null,"display_name":"P. M. Andrade","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102939073","display_name":"Universidade Estadual do Cear\u00e1","ror":"https://ror.org/00sec1m50","country_code":"BR","type":"education","lineage":["https://openalex.org/I102939073"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"P. M. Andrade","raw_affiliation_strings":["ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]},{"raw_affiliation_string":"Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083562770","display_name":"C.A.P. Lopes","orcid":"https://orcid.org/0000-0002-7479-4435","observed_orcids":["https://orcid.org/0000-0002-7479-4435"]},"institutions":[{"id":"https://openalex.org/I102939073","display_name":"Universidade Estadual do Cear\u00e1","ror":"https://ror.org/00sec1m50","country_code":"BR","type":"education","lineage":["https://openalex.org/I102939073"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"C. A. P. Lopes","raw_affiliation_strings":["ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]},{"raw_affiliation_string":"Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082604016","display_name":"Carlos Eduardo A. Souza","orcid":"https://orcid.org/0009-0000-0649-8098","observed_orcids":["https://orcid.org/0009-0000-0649-8098"]},"institutions":[{"id":"https://openalex.org/I243754102","display_name":"Universidade Federal do Cear\u00e1","ror":"https://ror.org/03srtnf24","country_code":"BR","type":"education","lineage":["https://openalex.org/I243754102"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"C. E. A. Souza","raw_affiliation_strings":["BDepartment of Animal Science, Federal University of Cear\u00e1, Av. Mister Hull S/N, Campus Pici, 60021-970, Fortaleza, CE, Brazil","Department of Animal Science, Federal University of Cear\u00e1, Av. Mister Hull S/N, Campus Pici, 60021-970, Fortaleza, CE, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BDepartment of Animal Science, Federal University of Cear\u00e1, Av. Mister Hull S/N, Campus Pici, 60021-970, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I243754102"]},{"raw_affiliation_string":"Department of Animal Science, Federal University of Cear\u00e1, Av. Mister Hull S/N, Campus Pici, 60021-970, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I243754102"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055221391","display_name":"Arlindo A. Moura","orcid":"https://orcid.org/0000-0002-8271-5733","observed_orcids":["https://orcid.org/0000-0002-8271-5733"]},"institutions":[{"id":"https://openalex.org/I243754102","display_name":"Universidade Federal do Cear\u00e1","ror":"https://ror.org/03srtnf24","country_code":"BR","type":"education","lineage":["https://openalex.org/I243754102"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"A. A. A. Moura","raw_affiliation_strings":["BDepartment of Animal Science, Federal University of Cear\u00e1, Av. Mister Hull S/N, Campus Pici, 60021-970, Fortaleza, CE, Brazil","Department of Animal Science, Federal University of Cear\u00e1, Av. Mister Hull S/N, Campus Pici, 60021-970, Fortaleza, CE, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BDepartment of Animal Science, Federal University of Cear\u00e1, Av. Mister Hull S/N, Campus Pici, 60021-970, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I243754102"]},{"raw_affiliation_string":"Department of Animal Science, Federal University of Cear\u00e1, Av. Mister Hull S/N, Campus Pici, 60021-970, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I243754102"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030869706","display_name":"C.C. Campello","orcid":"https://orcid.org/0000-0001-8808-4832","observed_orcids":["https://orcid.org/0000-0001-8808-4832"]},"institutions":[{"id":"https://openalex.org/I102939073","display_name":"Universidade Estadual do Cear\u00e1","ror":"https://ror.org/00sec1m50","country_code":"BR","type":"education","lineage":["https://openalex.org/I102939073"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"C. C. Campello","raw_affiliation_strings":["ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]},{"raw_affiliation_string":"Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019226350","display_name":"S\u00f4nia Nair B\u00e1o","orcid":"https://orcid.org/0000-0002-9873-3098","observed_orcids":["https://orcid.org/0000-0002-9873-3098"]},"institutions":[{"id":"https://openalex.org/I150729083","display_name":"Universidade de Bras\u00edlia","ror":"https://ror.org/02xfp8v59","country_code":"BR","type":"education","lineage":["https://openalex.org/I150729083"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"S. N. B\u00e1o","raw_affiliation_strings":["CDepartament of Cell Biology, University of Bras\u00edlia, Campus Universit\u00e1rio Darcy Ribeiro (Asa Norte), 70919-970, Bras\u00edlia, DF, Brazil","Departament of Cell Biology, University of Bras\u00edlia, Campus Universit\u00e1rio Darcy Ribeiro (Asa Norte), 70919-970, Bras\u00edlia, DF, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CDepartament of Cell Biology, University of Bras\u00edlia, Campus Universit\u00e1rio Darcy Ribeiro (Asa Norte), 70919-970, Bras\u00edlia, DF, Brazil","institution_ids":["https://openalex.org/I150729083"]},{"raw_affiliation_string":"Departament of Cell Biology, University of Bras\u00edlia, Campus Universit\u00e1rio Darcy Ribeiro (Asa Norte), 70919-970, Bras\u00edlia, DF, Brazil","institution_ids":["https://openalex.org/I150729083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050882241","display_name":"Johan E. J. Smitz","orcid":"https://orcid.org/0000-0002-5857-6542","observed_orcids":["https://orcid.org/0000-0002-5857-6542"]},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"J. Smitz","raw_affiliation_strings":["DFollicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium","Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DFollicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium","institution_ids":["https://openalex.org/I13469542"]},{"raw_affiliation_string":"Follicle Biology Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium","institution_ids":["https://openalex.org/I13469542"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023210157","display_name":"J.R. Figueiredo","orcid":"https://orcid.org/0000-0002-5139-0964","observed_orcids":["https://orcid.org/0000-0002-5139-0964"]},"institutions":[{"id":"https://openalex.org/I102939073","display_name":"Universidade Estadual do Cear\u00e1","ror":"https://ror.org/00sec1m50","country_code":"BR","type":"education","lineage":["https://openalex.org/I102939073"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"J. R. Figueiredo","raw_affiliation_strings":["ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ALaboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]},{"raw_affiliation_string":"Laboratory of Manipulation of Oocytes and Preantral Follicles (LAMOFOPA), Faculty of Veterinary Medicine, State University of Cear\u00e1, Av. Paranjana 1700, Campus Itaperi, 60740-903, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I102939073"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5029833161"],"corresponding_institution_ids":["https://openalex.org/I102939073"],"apc_list":null,"apc_paid":null,"fwci":0.494,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.64050122,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"25","issue":"6","first_page":"955","last_page":"965"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10584","display_name":"Reproductive Physiology in Livestock","score":0.012799999676644802,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11505","display_name":"Reproductive biology and impacts on aquatic species","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/growth-differentiation-factor-9","display_name":"growth differentiation factor 9","score":0.9160000085830688},{"id":"https://openalex.org/keywords/follicle-stimulating-hormone","display_name":"follicle-stimulating hormone","score":0.9729999899864197},{"id":"https://openalex.org/keywords/follicle-survival","display_name":"follicle survival","score":0.578000009059906},{"id":"https://openalex.org/keywords/follicular-development","display_name":"folliculogenesis","score":0.6669999957084656},{"id":"https://openalex.org/keywords/primordial-follicle-activation","display_name":"primordial follicle activation","score":0.8289999961853027},{"id":"https://openalex.org/keywords/follicle-ultrastructure","display_name":"follicle ultrastructure","score":0.6330000162124634},{"id":"https://openalex.org/keywords/oogenesis","display_name":"oogenesis","score":0.4729999899864197},{"id":"https://openalex.org/keywords/in-vitro-follicle-culture","display_name":"in vitro follicle culture","score":0.5450000166893005}],"concepts":[{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.5742110013961792},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5477685928344727},{"id":"https://openalex.org/C187785154","wikidata":"https://www.wikidata.org/wiki/Q5464664","display_name":"Follicular phase","level":2,"score":0.543810248374939},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5084256529808044},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4419098496437073},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4340519905090332},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3254026770591736},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11220705509185791},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06208297610282898}],"mesh":[{"descriptor_ui":"D000003","descriptor_name":"Abattoirs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001938","descriptor_name":"Brazil","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003433","descriptor_name":"Crosses, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005300","descriptor_name":"Fertility Agents, Female","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005640","descriptor_name":"Follicle Stimulating Hormone","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005640","descriptor_name":"Follicle Stimulating Hormone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006041","descriptor_name":"Goats","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006080","descriptor_name":"Ovarian Follicle","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006080","descriptor_name":"Ovarian Follicle","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006080","descriptor_name":"Ovarian Follicle","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D009866","descriptor_name":"Oogenesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046509","descriptor_name":"Tissue Culture Techniques","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D055429","descriptor_name":"Growth Differentiation Factor 9","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055429","descriptor_name":"Growth Differentiation Factor 9","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D059471","descriptor_name":"In Vitro Oocyte Maturation Techniques","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1071/rd12180","doi":"https://doi.org/10.1071/rd12180","is_oa":false,"landing_page_url":"https://doi.org/10.1071/rd12180","pdf_url":null,"source":{"id":"https://openalex.org/S199941106","display_name":"Reproduction Fertility and Development","issn_l":"1031-3613","issn":["1031-3613","1448-5990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320302","host_organization_name":"CSIRO Publishing","host_organization_lineage":["https://openalex.org/P4310320302"],"host_organization_lineage_names":["CSIRO Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction, Fertility and Development","raw_type":"journal-article"},{"id":"pmid:23050662","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23050662","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction, fertility, and development","raw_type":"Comparative Study"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:81630","doi":null,"is_oa":false,"landing_page_url":"https://biblio.vub.ac.be/vubir/dynamic-medium-containing-growth-differentiation-factor9-and-fsh-maintains-survival-and-promotes-in-vitro-growth-of-caprine-preantral-follicles-after-longterm-in-vitro-culture(45855462-0f16-4509-9aa3-e17ddf9ac2b9).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4043000042438507,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W102678112","https://openalex.org/W1594268777","https://openalex.org/W1964214826","https://openalex.org/W1968409042","https://openalex.org/W1968995478","https://openalex.org/W1985492640","https://openalex.org/W1990944409","https://openalex.org/W2003958928","https://openalex.org/W2012049945","https://openalex.org/W2013377055","https://openalex.org/W2017846182","https://openalex.org/W2018831893","https://openalex.org/W2024481165","https://openalex.org/W2040143097","https://openalex.org/W2040525542","https://openalex.org/W2041932804","https://openalex.org/W2044230763","https://openalex.org/W2050057651","https://openalex.org/W2055219121","https://openalex.org/W2058828171","https://openalex.org/W2068324526","https://openalex.org/W2069712264","https://openalex.org/W2073277515","https://openalex.org/W2084723435","https://openalex.org/W2106138862","https://openalex.org/W2106787268","https://openalex.org/W2113746705","https://openalex.org/W2115131050","https://openalex.org/W2116734686","https://openalex.org/W2116869982","https://openalex.org/W2118503490","https://openalex.org/W2127151362","https://openalex.org/W2129225495","https://openalex.org/W2134855625","https://openalex.org/W2138268960","https://openalex.org/W2138965475","https://openalex.org/W2147507486","https://openalex.org/W2147629399","https://openalex.org/W2148809908","https://openalex.org/W2155277570","https://openalex.org/W2166076551"],"related_works":["https://openalex.org/W2093313776","https://openalex.org/W7119361299","https://openalex.org/W2163708562","https://openalex.org/W2024481165","https://openalex.org/W2007478571","https://openalex.org/W2990008733","https://openalex.org/W2082670412","https://openalex.org/W1973218839","https://openalex.org/W1998790554","https://openalex.org/W4386959708"],"abstract_inverted_index":{"The":[0],"aim":[1],"of":[2,11,24,73,94,121,143,176,183,190,196,214,224],"the":[3,9,20,69,85,95,141,173,177,188,194],"present":[4],"study":[5],"was":[6,156],"to":[7],"evaluate":[8],"effects":[10],"growth":[12,218],"differentiation":[13],"factor":[14],"9":[15],"(GDF-9)":[16],"and":[17,61,99,106,146,205,211,217],"FSH":[18,82,117,138,170,206],"on":[19],"in":[21,36,68,153,172,193,221],"vitro":[22,222],"development":[23],"caprine":[25],"preantral":[26,226],"follicles":[27,145,191,216],"cultured":[28,35,100,192],"for":[29,104],"16":[30,110,181],"days.":[31],"Ovarian":[32],"fragments":[33,101],"were":[34,102],"\u03b1MEM\u207a":[37,126],"(\u03b1-minimum":[38],"essential":[39],"medium,":[40],"pH":[41],"7.2-7.4,":[42],"10":[43],"\u03bcg":[44,48],"mL\u207b\u00b9":[45,49,53,64,76,81],"insulin,":[46],"5.5":[47],"transferrin,":[50],"5.0":[51],"ng":[52,75,80],"selenium,":[54],"2":[55,58],"mM":[56,59],"glutamine,":[57],"hypoxanthine":[60],"1.25":[62],"mg":[63],"bovine":[65],"serum":[66],"albumin)":[67],"absence":[70],"or":[71,116],"presence":[72,195],"200":[74],"GDF-9":[77,115,136,164,204],"and/or":[78,89,137],"50":[79],"added":[83],"during":[84,219],"first":[86],"(Days":[87,91],"0-8)":[88],"second":[90,174],"8-16)":[92],"half":[93,175],"culture":[96,133,161,178,223],"period.":[97,179],"Non-cultured":[98],"processed":[103],"histological":[105],"ultrastructural":[107,185],"analyses.":[108],"After":[109,180],"days,":[111],"all":[112],"treatments":[113],"using":[114],"showed":[118],"higher":[119],"rates":[120],"follicular":[122,209],"survival":[123],"compared":[124],"with":[125,129,159],"alone.":[127],"Compared":[128],"non-cultured":[130],"control,":[131],"sequential":[132,160],"media":[134],"containing":[135,163,203],"significantly":[139],"increased":[140],"percentage":[142],"developing":[144],"follicle":[147],"diameter.":[148],"Moreover,":[149],"a":[150,200],"progressive":[151],"increase":[152],"oocyte":[154],"diameter":[155],"observed":[157],"only":[158],"medium":[162,202],"until":[165],"Day":[166],"8":[167],"followed":[168],"by":[169],"(GDF-9/FSH)":[171,207],"days":[182],"culture,":[184],"analysis":[186],"confirmed":[187],"integrity":[189,210],"GDF-9/FSH.":[197],"In":[198],"conclusion,":[199],"dynamic":[201],"maintained":[208],"promoted":[212],"activation":[213],"primordial":[215],"long-term":[220],"goat":[225],"follicles.":[227]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}