{"id":"https://openalex.org/W1983285616","doi":"https://doi.org/10.1053/j.ajkd.2009.12.022","title":"Pathogenesis of Hypertension: Interactions Among Sodium, Potassium, and Aldosterone","display_name":"Pathogenesis of Hypertension: Interactions Among Sodium, Potassium, and Aldosterone","publication_year":2010,"publication_date":"2010-03-15","ids":{"openalex":"https://openalex.org/W1983285616","doi":"https://doi.org/10.1053/j.ajkd.2009.12.022","mag":"1983285616","pmid":"https://pubmed.ncbi.nlm.nih.gov/20223568"},"language":"en","primary_location":{"id":"doi:10.1053/j.ajkd.2009.12.022","doi":"https://doi.org/10.1053/j.ajkd.2009.12.022","is_oa":false,"landing_page_url":"https://doi.org/10.1053/j.ajkd.2009.12.022","pdf_url":null,"source":{"id":"https://openalex.org/S18197459","display_name":"American Journal of Kidney Diseases","issn_l":"0272-6386","issn":["0272-6386","1523-6838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Kidney Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087457250","display_name":"Eckhart B\u00fcssemaker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103666","display_name":"University Hospital M\u00fcnster","ror":"https://ror.org/01856cw59","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210103666"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Eckhart B\u00fcssemaker","raw_affiliation_strings":["Medizinische Klinik und Poliklinik D, Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster, Germany. buessema@hotmail.com","Medizinische Klinik und Poliklinik D, Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medizinische Klinik und Poliklinik D, Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster, Germany. buessema@hotmail.com","institution_ids":["https://openalex.org/I4210103666"]},{"raw_affiliation_string":"Medizinische Klinik und Poliklinik D, Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I4210103666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027123104","display_name":"Uta Hillebrand","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103666","display_name":"University Hospital M\u00fcnster","ror":"https://ror.org/01856cw59","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210103666"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Uta Hillebrand","raw_affiliation_strings":["Medizinische Klinik und Poliklinik D, Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medizinische Klinik und Poliklinik D, Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I4210103666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112768507","display_name":"Martin Hausberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210090715","display_name":"St\u00e4dtisches Klinikum Karlsruhe","ror":"https://ror.org/00agtat91","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210090715"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin Hausberg","raw_affiliation_strings":["Medizinische Klinik I, St\u00e4dtisches Klinikum Karlsruhe, Karlsruhe, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medizinische Klinik I, St\u00e4dtisches Klinikum Karlsruhe, Karlsruhe, Germany","institution_ids":["https://openalex.org/I4210090715"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049644996","display_name":"Hermann Josef Pavenst\u00e4dt","orcid":"https://orcid.org/0000-0001-8717-7770","observed_orcids":["https://orcid.org/0000-0001-8717-7770"]},"institutions":[{"id":"https://openalex.org/I4210103666","display_name":"University Hospital M\u00fcnster","ror":"https://ror.org/01856cw59","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210103666"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hermann Pavenst\u00e4dt","raw_affiliation_strings":["Medizinische Klinik und Poliklinik D, Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medizinische Klinik und Poliklinik D, Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I4210103666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017239585","display_name":"Hans Oberleithner","orcid":"https://orcid.org/0000-0002-1151-4010","observed_orcids":["https://orcid.org/0000-0002-1151-4010"]},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hans Oberleithner","raw_affiliation_strings":["Institut f\u00fcr Physiologie II, Westf\u00e4lische Wilhelms-Universit\u00e4t, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Physiologie II, Westf\u00e4lische Wilhelms-Universit\u00e4t, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5087457250"],"corresponding_institution_ids":["https://openalex.org/I4210103666"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":5.7864,"has_fulltext":false,"cited_by_count":73,"citation_normalized_percentile":{"value":0.95804196,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"55","issue":"6","first_page":"1111","last_page":"1120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12075","display_name":"Sodium Intake and Health","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12075","display_name":"Sodium Intake and Health","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.777999997138977},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.843999981880188},{"id":"https://openalex.org/keywords/sodium-intake","display_name":"sodium intake","score":0.7289999723434448},{"id":"https://openalex.org/keywords/potassium-intake","display_name":"potassium intake","score":0.9100000262260437},{"id":"https://openalex.org/keywords/aldosterone","display_name":"aldosterone","score":0.9549999833106995},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.9670000076293945},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.8339999914169312},{"id":"https://openalex.org/keywords/low-sodium-diet","display_name":"sodium restriction","score":0.6050000190734863},{"id":"https://openalex.org/keywords/potassium-supplementation","display_name":"potassium supplementation","score":0.6010000109672546},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.8479999899864197}],"concepts":[{"id":"https://openalex.org/C2778525890","wikidata":"https://www.wikidata.org/wiki/Q184564","display_name":"Aldosterone","level":2,"score":0.8039484620094299},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7842310667037964},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.6110646724700928},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6015439629554749},{"id":"https://openalex.org/C2780972559","wikidata":"https://www.wikidata.org/wiki/Q550061","display_name":"Endothelial dysfunction","level":2,"score":0.5330796241760254},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5164663791656494},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5109314322471619},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5003619194030762},{"id":"https://openalex.org/C517785266","wikidata":"https://www.wikidata.org/wiki/Q703","display_name":"Potassium","level":2,"score":0.4367930591106415},{"id":"https://openalex.org/C2775850156","wikidata":"https://www.wikidata.org/wiki/Q4797538","display_name":"Arterial stiffness","level":3,"score":0.4338882267475128},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.43356502056121826},{"id":"https://openalex.org/C3020131227","wikidata":"https://www.wikidata.org/wiki/Q824292","display_name":"Low sodium","level":3,"score":0.422616571187973},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.09352213144302368},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.05366051197052002},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000450","descriptor_name":"Aldosterone","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004548","descriptor_name":"Elasticity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012964","descriptor_name":"Sodium","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012982","descriptor_name":"Sodium, Dietary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014655","descriptor_name":"Vascular Resistance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017419","descriptor_name":"Potassium, Dietary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1053/j.ajkd.2009.12.022","doi":"https://doi.org/10.1053/j.ajkd.2009.12.022","is_oa":false,"landing_page_url":"https://doi.org/10.1053/j.ajkd.2009.12.022","pdf_url":null,"source":{"id":"https://openalex.org/S18197459","display_name":"American Journal of Kidney Diseases","issn_l":"0272-6386","issn":["0272-6386","1523-6838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Kidney Diseases","raw_type":"journal-article"},{"id":"pmid:20223568","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20223568","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of kidney diseases : the official journal of the National Kidney Foundation","raw_type":"Case Reports"},{"id":"mag:2787274579","doi":null,"is_oa":false,"landing_page_url":"https://www.ajkd.org/article/S0272-6386(09)01660-6/pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9789000153541565,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3938127292","display_name":null,"funder_award_id":"OB 63/17\u20101","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W170506265","https://openalex.org/W1481480932","https://openalex.org/W1546802604","https://openalex.org/W1591223527","https://openalex.org/W1931790262","https://openalex.org/W1964860798","https://openalex.org/W1965430847","https://openalex.org/W1966258987","https://openalex.org/W1970947429","https://openalex.org/W1976183622","https://openalex.org/W1978736086","https://openalex.org/W1987991086","https://openalex.org/W1989722803","https://openalex.org/W1994199177","https://openalex.org/W2000392454","https://openalex.org/W2002514810","https://openalex.org/W2003272398","https://openalex.org/W2003761577","https://openalex.org/W2004463190","https://openalex.org/W2006910397","https://openalex.org/W2013154098","https://openalex.org/W2015202011","https://openalex.org/W2016703981","https://openalex.org/W2017821597","https://openalex.org/W2018299587","https://openalex.org/W2020121600","https://openalex.org/W2021538045","https://openalex.org/W2023255019","https://openalex.org/W2023313831","https://openalex.org/W2031732867","https://openalex.org/W2032110253","https://openalex.org/W2034349743","https://openalex.org/W2046903020","https://openalex.org/W2054570198","https://openalex.org/W2061306975","https://openalex.org/W2065056554","https://openalex.org/W2065712444","https://openalex.org/W2073236176","https://openalex.org/W2076347631","https://openalex.org/W2079844481","https://openalex.org/W2083771672","https://openalex.org/W2084477357","https://openalex.org/W2087061471","https://openalex.org/W2088908903","https://openalex.org/W2095330664","https://openalex.org/W2103093968","https://openalex.org/W2105640139","https://openalex.org/W2107826105","https://openalex.org/W2111948630","https://openalex.org/W2114290793","https://openalex.org/W2115648058","https://openalex.org/W2119620107","https://openalex.org/W2121809636","https://openalex.org/W2122376672","https://openalex.org/W2128758059","https://openalex.org/W2131957890","https://openalex.org/W2133877420","https://openalex.org/W2134952879","https://openalex.org/W2140024548","https://openalex.org/W2140616692","https://openalex.org/W2141999915","https://openalex.org/W2145989311","https://openalex.org/W2148222582","https://openalex.org/W2150931520","https://openalex.org/W2151277237","https://openalex.org/W2154055479","https://openalex.org/W2155905764","https://openalex.org/W2157151850","https://openalex.org/W2160393148","https://openalex.org/W2160414655","https://openalex.org/W2166318460","https://openalex.org/W2170023925","https://openalex.org/W2193246905","https://openalex.org/W2206880975","https://openalex.org/W2341645956","https://openalex.org/W2587328176"],"related_works":["https://openalex.org/W2787274579","https://openalex.org/W2147475975","https://openalex.org/W1990473978","https://openalex.org/W1976183622","https://openalex.org/W2074701449","https://openalex.org/W2009853706","https://openalex.org/W2323282160","https://openalex.org/W2113550575","https://openalex.org/W2070777185","https://openalex.org/W2330144001"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":10},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}