{"id":"https://openalex.org/W1983264479","doi":"https://doi.org/10.1016/j.abb.2014.08.014","title":"Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants","display_name":"Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants","publication_year":2014,"publication_date":"2014-08-27","ids":{"openalex":"https://openalex.org/W1983264479","doi":"https://doi.org/10.1016/j.abb.2014.08.014","mag":"1983264479","pmid":"https://pubmed.ncbi.nlm.nih.gov/25172223"},"language":"en","primary_location":{"id":"doi:10.1016/j.abb.2014.08.014","doi":"https://doi.org/10.1016/j.abb.2014.08.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.abb.2014.08.014","pdf_url":null,"source":{"id":"https://openalex.org/S153476765","display_name":"Archives of Biochemistry and Biophysics","issn_l":"0003-9861","issn":["0003-9861","1096-0384"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Biochemistry and Biophysics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056468557","display_name":"Vincent Bonifay","orcid":"https://orcid.org/0000-0003-4341-6981","observed_orcids":["https://orcid.org/0000-0003-4341-6981"]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vincent Bonifay","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046706301","display_name":"Tessa J. Barrett","orcid":"https://orcid.org/0000-0003-0751-1578","observed_orcids":["https://orcid.org/0000-0003-0751-1578"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I2801241159","display_name":"The Heart Research Institute","ror":"https://ror.org/046fa4y88","country_code":"AU","type":"facility","lineage":["https://openalex.org/I2801241159"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Tessa J. Barrett","raw_affiliation_strings":["Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia; Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia","Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia; Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","institution_ids":["https://openalex.org/I129604602","https://openalex.org/I2801241159"]},{"raw_affiliation_string":"Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia","institution_ids":["https://openalex.org/I2801241159"]},{"raw_affiliation_string":"Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102867354","display_name":"David I. Pattison","orcid":"https://orcid.org/0000-0002-8156-3619","observed_orcids":["https://orcid.org/0000-0002-8156-3619"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I2801241159","display_name":"The Heart Research Institute","ror":"https://ror.org/046fa4y88","country_code":"AU","type":"facility","lineage":["https://openalex.org/I2801241159"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David I. Pattison","raw_affiliation_strings":["Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia; Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia","Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia; Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","institution_ids":["https://openalex.org/I129604602","https://openalex.org/I2801241159"]},{"raw_affiliation_string":"Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia","institution_ids":["https://openalex.org/I2801241159"]},{"raw_affiliation_string":"Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069317976","display_name":"Michael J. Davies","orcid":"https://orcid.org/0000-0002-5196-6919","observed_orcids":["https://orcid.org/0000-0002-5196-6919"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I2801241159","display_name":"The Heart Research Institute","ror":"https://ror.org/046fa4y88","country_code":"AU","type":"facility","lineage":["https://openalex.org/I2801241159"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Michael J. Davies","raw_affiliation_strings":["Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia; Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia","Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia; Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","institution_ids":["https://openalex.org/I129604602","https://openalex.org/I2801241159"]},{"raw_affiliation_string":"Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia","institution_ids":["https://openalex.org/I2801241159"]},{"raw_affiliation_string":"Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082145076","display_name":"Clare Louise Hawkins","orcid":"https://orcid.org/0000-0003-2738-5089","observed_orcids":["https://orcid.org/0000-0003-2738-5089"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I2801241159","display_name":"The Heart Research Institute","ror":"https://ror.org/046fa4y88","country_code":"AU","type":"facility","lineage":["https://openalex.org/I2801241159"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Clare L. Hawkins","raw_affiliation_strings":["Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia; Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia","Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia; Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","institution_ids":["https://openalex.org/I129604602","https://openalex.org/I2801241159"]},{"raw_affiliation_string":"Heart Research Institute, 7 Eliza St, Newtown, NSW 2042, Australia","institution_ids":["https://openalex.org/I2801241159"]},{"raw_affiliation_string":"Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086031829","display_name":"Michael T. Ashby","orcid":"https://orcid.org/0000-0003-1875-4823","observed_orcids":["https://orcid.org/0000-0003-1875-4823"]},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael T. Ashby","raw_affiliation_strings":["Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA. Electronic address: mashby@ou.edu","Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA. Electronic address: mashby@ou.edu","institution_ids":["https://openalex.org/I8692664"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA","institution_ids":["https://openalex.org/I8692664"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5086031829"],"corresponding_institution_ids":["https://openalex.org/I8692664"],"apc_list":{"value":3170,"currency":"USD","value_usd":3170},"apc_paid":null,"fwci":0.4566,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.62393162,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"564","issue":null,"first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.5967000126838684,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.5967000126838684,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.37720000743865967,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tryptophan-oxidation","display_name":"tryptophan oxidation","score":1.0},{"id":"https://openalex.org/keywords/thiocyanate","display_name":"thiocyanate","score":0.9549999833106995},{"id":"https://openalex.org/keywords/hypothiocyanous-acid","display_name":"hypothiocyanous acid","score":0.9210000038146973},{"id":"https://openalex.org/keywords/thiocyanogen","display_name":"thiocyanogen","score":0.9449999928474426},{"id":"https://openalex.org/keywords/lactoperoxidase","display_name":"lactoperoxidase","score":0.9919999837875366},{"id":"https://openalex.org/keywords/myeloperoxidase","display_name":"myeloperoxidase","score":1.0},{"id":"https://openalex.org/keywords/ph-dependence","display_name":"pH dependence","score":0.5590000152587891},{"id":"https://openalex.org/keywords/protein-oxidation","display_name":"protein oxidation","score":0.5730000138282776},{"id":"https://openalex.org/keywords/thiol-oxidation","display_name":"thiol oxidation","score":0.6930000185966492},{"id":"https://openalex.org/keywords/hypohalous-acids","display_name":"hypohalous acids","score":0.7710000276565552},{"id":"https://openalex.org/keywords/comproportionation","display_name":"comproportionation","score":0.6299999952316284}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8663075566291809},{"id":"https://openalex.org/C2776294642","wikidata":"https://www.wikidata.org/wiki/Q77747995","display_name":"Thiocyanate","level":2,"score":0.7842567563056946},{"id":"https://openalex.org/C2776706248","wikidata":"https://www.wikidata.org/wiki/Q181003","display_name":"Tryptophan","level":3,"score":0.6692544221878052},{"id":"https://openalex.org/C203565725","wikidata":"https://www.wikidata.org/wiki/Q420012","display_name":"Myeloperoxidase","level":3,"score":0.5450717210769653},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5449693202972412},{"id":"https://openalex.org/C162008176","wikidata":"https://www.wikidata.org/wiki/Q419305","display_name":"Peroxidase","level":3,"score":0.5058073997497559},{"id":"https://openalex.org/C2780908991","wikidata":"https://www.wikidata.org/wiki/Q407318","display_name":"Hypochlorous acid","level":2,"score":0.49798107147216797},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.48808395862579346},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.35772791504859924},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3304319381713867},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.29839015007019043},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06460046768188477},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013861","descriptor_name":"Thiocyanates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013861","descriptor_name":"Thiocyanates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014364","descriptor_name":"Tryptophan","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014364","descriptor_name":"Tryptophan","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D016877","descriptor_name":"Oxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016877","descriptor_name":"Oxidants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.abb.2014.08.014","doi":"https://doi.org/10.1016/j.abb.2014.08.014","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.abb.2014.08.014","pdf_url":null,"source":{"id":"https://openalex.org/S153476765","display_name":"Archives of Biochemistry and Biophysics","issn_l":"0003-9861","issn":["0003-9861","1096-0384"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Biochemistry and Biophysics","raw_type":"journal-article"},{"id":"pmid:25172223","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25172223","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of biochemistry and biophysics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1530189922","display_name":"Chemical Mechanisms of Reactive Sulfur Species","funder_award_id":"0911328","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6441658541","display_name":"Cellular mechanisms linking smoking and cardiovascular disease","funder_award_id":"FT120100682","funder_id":"https://openalex.org/F4320334704","funder_display_name":"Australian Research Council"},{"id":"https://openalex.org/G7958496183","display_name":"ARC Centre of Excellence - Centre for Free Radical Chemistry and Biotechnology","funder_award_id":"CE0561607","funder_id":"https://openalex.org/F4320334704","funder_display_name":"Australian Research Council"},{"id":"https://openalex.org/G8304624976","display_name":"Mechanisms and consequences of myeloperoxidase-mediated damage to glycosaminoglycans, proteins and proteoglycans","funder_award_id":"DP0988311","funder_id":"https://openalex.org/F4320334704","funder_display_name":"Australian Research Council"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320334704","display_name":"Australian Research Council","ror":"https://ror.org/05mmh0f86"},{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1525146040","https://openalex.org/W1600682462","https://openalex.org/W1967766823","https://openalex.org/W1971435128","https://openalex.org/W1973416818","https://openalex.org/W1978854151","https://openalex.org/W1985431868","https://openalex.org/W1986529239","https://openalex.org/W1992946202","https://openalex.org/W1994430921","https://openalex.org/W2002033397","https://openalex.org/W2002886146","https://openalex.org/W2010686434","https://openalex.org/W2021071169","https://openalex.org/W2028560320","https://openalex.org/W2039042657","https://openalex.org/W2047430972","https://openalex.org/W2055328329","https://openalex.org/W2056485774","https://openalex.org/W2060267840","https://openalex.org/W2060372477","https://openalex.org/W2061679481","https://openalex.org/W2063794161","https://openalex.org/W2065626113","https://openalex.org/W2066066061","https://openalex.org/W2070619662","https://openalex.org/W2073089909","https://openalex.org/W2075288834","https://openalex.org/W2076971907","https://openalex.org/W2079564793","https://openalex.org/W2080616868","https://openalex.org/W2093705349","https://openalex.org/W2094605315","https://openalex.org/W2094728118","https://openalex.org/W2139564185","https://openalex.org/W2151565185","https://openalex.org/W2155028613","https://openalex.org/W2292720972","https://openalex.org/W2314530439","https://openalex.org/W2328324507","https://openalex.org/W2745334645","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2094728118","https://openalex.org/W2065626113","https://openalex.org/W2028447896","https://openalex.org/W2054781317","https://openalex.org/W2745334645","https://openalex.org/W2510152778","https://openalex.org/W2036099283","https://openalex.org/W2075288834","https://openalex.org/W2055280915","https://openalex.org/W2080764132"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}