{"id":"https://openalex.org/W1983187671","doi":"https://doi.org/10.1016/0014-4886(72)90056-8","title":"Effects of L-DOPA on the EEG and brain amines of unrestrained rats","display_name":"Effects of L-DOPA on the EEG and brain amines of unrestrained rats","publication_year":1972,"publication_date":"1972-04-01","ids":{"openalex":"https://openalex.org/W1983187671","doi":"https://doi.org/10.1016/0014-4886(72)90056-8","mag":"1983187671","pmid":"https://pubmed.ncbi.nlm.nih.gov/5026410"},"language":"en","primary_location":{"id":"doi:10.1016/0014-4886(72)90056-8","doi":"https://doi.org/10.1016/0014-4886(72)90056-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0014-4886(72)90056-8","pdf_url":null,"source":{"id":"https://openalex.org/S165592611","display_name":"Experimental Neurology","issn_l":"0014-4886","issn":["0014-4886","1090-2430"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Neurology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111880325","display_name":"Paul D. Thut","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]},{"id":"https://openalex.org/I4390039337","display_name":"Dartmouth Health","ror":"https://ror.org/01pa9ed26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I107672454","https://openalex.org/I4390039337"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul D. Thut","raw_affiliation_strings":["Department of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA","institution_ids":["https://openalex.org/I107672454","https://openalex.org/I4390039337"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011816558","display_name":"Richard H. Rech","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]},{"id":"https://openalex.org/I4390039337","display_name":"Dartmouth Health","ror":"https://ror.org/01pa9ed26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I107672454","https://openalex.org/I4390039337"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard H. Rech","raw_affiliation_strings":["Department of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA","institution_ids":["https://openalex.org/I107672454","https://openalex.org/I4390039337"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4110,"currency":"USD","value_usd":4110},"apc_paid":null,"fwci":0.7692,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.62266703,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"35","issue":"1","first_page":"13","last_page":"29"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.032099999487400055,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.024000000208616257,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/l-dopa","display_name":"L-DOPA","score":0.996999979019165},{"id":"https://openalex.org/keywords/eeg-desynchronization","display_name":"EEG desynchronization","score":0.8709999918937683},{"id":"https://openalex.org/keywords/brain-amines","display_name":"brain amines","score":0.8709999918937683},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.777999997138977},{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.8740000128746033},{"id":"https://openalex.org/keywords/diethyldithiocarbamate","display_name":"diethyldithiocarbamate","score":0.8880000114440918},{"id":"https://openalex.org/keywords/isocarboxazid","display_name":"isocarboxazid","score":0.9390000104904175},{"id":"https://openalex.org/keywords/ro-4-4602","display_name":"Ro 4-4602","score":0.9900000095367432},{"id":"https://openalex.org/keywords/dopamine-beta-hydroxylase-inhibition","display_name":"dopamine beta-hydroxylase inhibition","score":0.8149999976158142},{"id":"https://openalex.org/keywords/noradrenergic-neurons","display_name":"noradrenergic neurons","score":0.7020000219345093},{"id":"https://openalex.org/keywords/serotonergic-neurons","display_name":"serotonergic neurons","score":0.9409999847412109},{"id":"https://openalex.org/keywords/drug-interactions","display_name":"drug interactions","score":0.41100001335144043}],"concepts":[{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.7925442457199097},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.7074216604232788},{"id":"https://openalex.org/C37000724","wikidata":"https://www.wikidata.org/wiki/Q50430226","display_name":"Serotonergic","level":4,"score":0.6198614835739136},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.6109112501144409},{"id":"https://openalex.org/C2777440324","wikidata":"https://www.wikidata.org/wiki/Q4161984","display_name":"Dihydroxyphenylalanine","level":3,"score":0.4273656904697418},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.411948561668396},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.349447101354599},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.3414533734321594},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32155364751815796},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31827136874198914},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.31456252932548523},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.29616397619247437},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22887897491455078},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002219","descriptor_name":"Carbamates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002262","descriptor_name":"Carboxy-Lyases","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003201","descriptor_name":"Computers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004295","descriptor_name":"Dihydroxyphenylalanine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007520","descriptor_name":"Isocarboxazid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012694","descriptor_name":"Serine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0014-4886(72)90056-8","doi":"https://doi.org/10.1016/0014-4886(72)90056-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0014-4886(72)90056-8","pdf_url":null,"source":{"id":"https://openalex.org/S165592611","display_name":"Experimental Neurology","issn_l":"0014-4886","issn":["0014-4886","1090-2430"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Neurology","raw_type":"journal-article"},{"id":"pmid:5026410","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5026410","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental neurology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W12370593","https://openalex.org/W1543584051","https://openalex.org/W1935879618","https://openalex.org/W1966220164","https://openalex.org/W1967409927","https://openalex.org/W1968678744","https://openalex.org/W1975272257","https://openalex.org/W1986525767","https://openalex.org/W1989800691","https://openalex.org/W1991298950","https://openalex.org/W1992608453","https://openalex.org/W1995735449","https://openalex.org/W1996661746","https://openalex.org/W2005621289","https://openalex.org/W2009330496","https://openalex.org/W2010646452","https://openalex.org/W2011381010","https://openalex.org/W2016749528","https://openalex.org/W2017928974","https://openalex.org/W2019452316","https://openalex.org/W2030233249","https://openalex.org/W2031593624","https://openalex.org/W2033187857","https://openalex.org/W2047078631","https://openalex.org/W2059378567","https://openalex.org/W2062761306","https://openalex.org/W2082340202","https://openalex.org/W2092985089","https://openalex.org/W2094742279","https://openalex.org/W2100873780","https://openalex.org/W2110092291","https://openalex.org/W2127795105","https://openalex.org/W2164398262","https://openalex.org/W2271875845","https://openalex.org/W2410745145","https://openalex.org/W2441546745","https://openalex.org/W4234386942","https://openalex.org/W4406963436","https://openalex.org/W4407022944","https://openalex.org/W6683956868"],"related_works":["https://openalex.org/W2094742279","https://openalex.org/W2044302618","https://openalex.org/W1995735449","https://openalex.org/W2418059275","https://openalex.org/W2050783044","https://openalex.org/W1965403746","https://openalex.org/W2005111699","https://openalex.org/W4241756593","https://openalex.org/W2265229530","https://openalex.org/W1973322463"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}