{"id":"https://openalex.org/W1982980232","doi":"https://doi.org/10.1007/s11745-999-0444-y","title":"Metabolism of trideuterated iso\u2010lignoceric acid in rats in Vivo and in human fibroblasts in culture","display_name":"Metabolism of trideuterated iso\u2010lignoceric acid in rats in Vivo and in human fibroblasts in culture","publication_year":1999,"publication_date":"1999-09-01","ids":{"openalex":"https://openalex.org/W1982980232","doi":"https://doi.org/10.1007/s11745-999-0444-y","mag":"1982980232","pmid":"https://pubmed.ncbi.nlm.nih.gov/10574659"},"language":"en","primary_location":{"id":"doi:10.1007/s11745-999-0444-y","doi":"https://doi.org/10.1007/s11745-999-0444-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11745-999-0444-y","pdf_url":null,"source":{"id":"https://openalex.org/S115623499","display_name":"Lipids","issn_l":"0024-4201","issn":["0024-4201","1558-9307"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109075899","display_name":"Alfred Poulos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801308011","display_name":"Women's and Children's Hospital","ror":"https://ror.org/03kwrfk72","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2801308011"]},{"id":"https://openalex.org/I2802079659","display_name":"South Australian Water Corporation","ror":"https://ror.org/0220wzg80","country_code":"AU","type":"company","lineage":["https://openalex.org/I2802079659"]},{"id":"https://openalex.org/I4210100798","display_name":"Women's and Children's Health Network","ror":"https://ror.org/01e2ynf23","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210100798"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Alfred Poulos","raw_affiliation_strings":["BioMed Technology, 11 Brigalow Ave., Kensington Gardens, South Australia, 5068 Australia","Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia","South Australian Water Corporation, Hodgson Rd., Bolivar, South Australia, 5110 Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioMed Technology, 11 Brigalow Ave., Kensington Gardens, South Australia, 5068 Australia","institution_ids":[]},{"raw_affiliation_string":"Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia","institution_ids":["https://openalex.org/I2801308011","https://openalex.org/I4210100798"]},{"raw_affiliation_string":"South Australian Water Corporation, Hodgson Rd., Bolivar, South Australia, 5110 Australia","institution_ids":["https://openalex.org/I2802079659"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003714224","display_name":"Peter C. Stockham","orcid":"https://orcid.org/0000-0001-5093-5144","observed_orcids":["https://orcid.org/0000-0001-5093-5144"]},"institutions":[{"id":"https://openalex.org/I2801308011","display_name":"Women's and Children's Hospital","ror":"https://ror.org/03kwrfk72","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2801308011"]},{"id":"https://openalex.org/I4210100798","display_name":"Women's and Children's Health Network","ror":"https://ror.org/01e2ynf23","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210100798"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Peter C. Stockham","raw_affiliation_strings":["Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia","institution_ids":["https://openalex.org/I2801308011","https://openalex.org/I4210100798"]}]},{"author_position":"middle","author":{"id":null,"display_name":"David W. Johnson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801308011","display_name":"Women's and Children's Hospital","ror":"https://ror.org/03kwrfk72","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2801308011"]},{"id":"https://openalex.org/I4210100798","display_name":"Women's and Children's Health Network","ror":"https://ror.org/01e2ynf23","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210100798"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David W. Johnson","raw_affiliation_strings":["Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia","institution_ids":["https://openalex.org/I2801308011","https://openalex.org/I4210100798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059910395","display_name":"Barbara C. Paton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801308011","display_name":"Women's and Children's Hospital","ror":"https://ror.org/03kwrfk72","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2801308011"]},{"id":"https://openalex.org/I4210100798","display_name":"Women's and Children's Health Network","ror":"https://ror.org/01e2ynf23","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210100798"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Barbara C. Paton","raw_affiliation_strings":["Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia","institution_ids":["https://openalex.org/I2801308011","https://openalex.org/I4210100798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083671954","display_name":"Kaye Beckman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801308011","display_name":"Women's and Children's Hospital","ror":"https://ror.org/03kwrfk72","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2801308011"]},{"id":"https://openalex.org/I4210100798","display_name":"Women's and Children's Health Network","ror":"https://ror.org/01e2ynf23","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210100798"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Kaye Beckman","raw_affiliation_strings":["Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia","institution_ids":["https://openalex.org/I2801308011","https://openalex.org/I4210100798"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000414353","display_name":"Harmeet Singh","orcid":"https://orcid.org/0000-0002-1989-9066","observed_orcids":["https://orcid.org/0000-0002-1989-9066"]},"institutions":[{"id":"https://openalex.org/I2801308011","display_name":"Women's and Children's Hospital","ror":"https://ror.org/03kwrfk72","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2801308011"]},{"id":"https://openalex.org/I4210100798","display_name":"Women's and Children's Health Network","ror":"https://ror.org/01e2ynf23","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210100798"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Harmeet Singh","raw_affiliation_strings":["Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Pathology, Women's and Children's Hospital, 72 King William Rd., North Adelaide, South Australia, 5006 Australia","institution_ids":["https://openalex.org/I2801308011","https://openalex.org/I4210100798"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5059910395"],"corresponding_institution_ids":["https://openalex.org/I2801308011","https://openalex.org/I4210100798"],"apc_list":{"value":3589,"currency":"USD","value_usd":3589},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.11777978,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"34","issue":"9","first_page":"943","last_page":"949"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/very-long-chain-fatty-acids","display_name":"very long chain fatty acids","score":0.9629999995231628},{"id":"https://openalex.org/keywords/peroxisomal-beta-oxidation","display_name":"peroxisomal beta-oxidation","score":0.8790000081062317},{"id":"https://openalex.org/keywords/peroxisomal-disorders","display_name":"peroxisomal disorders","score":0.8830000162124634},{"id":"https://openalex.org/keywords/zellweger-syndrome","display_name":"Zellweger syndrome","score":0.9739999771118164},{"id":"https://openalex.org/keywords/fatty-acid-turnover","display_name":"fatty acid turnover","score":0.75},{"id":"https://openalex.org/keywords/human-dermal-fibroblasts","display_name":"human dermal fibroblasts","score":0.8080000281333923},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.7910000085830688},{"id":"https://openalex.org/keywords/odd-chain-fatty-acids","display_name":"odd-chain fatty acids","score":0.6430000066757202}],"concepts":[{"id":"https://openalex.org/C382228","wikidata":"https://www.wikidata.org/wiki/Q849994","display_name":"Clinical chemistry","level":2,"score":0.7171890735626221},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.7164958715438843},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.6919857859611511},{"id":"https://openalex.org/C22894154","wikidata":"https://www.wikidata.org/wiki/Q15483409","display_name":"Lipidology","level":3,"score":0.6358078718185425},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5591416954994202},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5082904696464539},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2936071753501892},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12726637721061707}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001812","descriptor_name":"Blood-Brain Barrier","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002849","descriptor_name":"Chromatography, Gas","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003903","descriptor_name":"Deuterium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015211","descriptor_name":"Zellweger Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020675","descriptor_name":"Peroxisomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s11745-999-0444-y","doi":"https://doi.org/10.1007/s11745-999-0444-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11745-999-0444-y","pdf_url":null,"source":{"id":"https://openalex.org/S115623499","display_name":"Lipids","issn_l":"0024-4201","issn":["0024-4201","1558-9307"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids","raw_type":"journal-article"},{"id":"pmid:10574659","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10574659","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids","raw_type":"Journal Article"},{"id":"pmh:oai:digital.library.adelaide.edu.au:2440/7659","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2440/7659","pdf_url":null,"source":{"id":"https://openalex.org/S4306401835","display_name":"Adelaide Research & Scholarship (AR&S) (University of Adelaide)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5681781","host_organization_name":"The University of Adelaide","host_organization_lineage":["https://openalex.org/I5681781"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://doi.org/10.1007/s11745-999-0444-y","raw_type":"Journal article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.4099999964237213,"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"},{"id":"https://openalex.org/F4320334737","display_name":"National Medical Research Council","ror":"https://ror.org/04x3cxs03"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1500311202","https://openalex.org/W1683037353","https://openalex.org/W1775638486","https://openalex.org/W1968447063","https://openalex.org/W1974658237","https://openalex.org/W1981970675","https://openalex.org/W1982059330","https://openalex.org/W1991493046","https://openalex.org/W1991664740","https://openalex.org/W2000256461","https://openalex.org/W2006359008","https://openalex.org/W2010687728","https://openalex.org/W2018791168","https://openalex.org/W2020044496","https://openalex.org/W2020287578","https://openalex.org/W2026939117","https://openalex.org/W2035026471","https://openalex.org/W2037167329","https://openalex.org/W2050926168","https://openalex.org/W2060401928","https://openalex.org/W2067071066","https://openalex.org/W2079884116","https://openalex.org/W2084400497","https://openalex.org/W2087481852","https://openalex.org/W2088260587","https://openalex.org/W2101153945","https://openalex.org/W2106485907","https://openalex.org/W2128635872","https://openalex.org/W2152311269","https://openalex.org/W2183926417","https://openalex.org/W2222090074","https://openalex.org/W2238205783","https://openalex.org/W2343627890","https://openalex.org/W4254198299"],"related_works":["https://openalex.org/W2151851024","https://openalex.org/W1775638486","https://openalex.org/W127480946","https://openalex.org/W2316662682","https://openalex.org/W1972891627","https://openalex.org/W2569540264","https://openalex.org/W2605752950","https://openalex.org/W3217110267","https://openalex.org/W63078969","https://openalex.org/W2183926417"],"abstract_inverted_index":{"Saturated":[0],"very":[1],"long":[2],"chain":[3,172],"fatty":[4,152],"acids":[5,7,74,112,214],"(fatty":[6],"with":[8,40,164,183],"greater":[9],"than":[10],"22":[11],"carbon":[12,171],"atoms;":[13],"VLCFA)":[14],"accumulate":[15],"in":[16,27,38,51,53,56,60,77,85,94,144,178,185],"peroxisomal":[17,186],"disorders,":[18,42],"but":[19,87],"there":[20,88],"is":[21],"little":[22,90,149],"information":[23],"on":[24],"their":[25,204],"turnover":[26,220],"patients.":[28],"To":[29],"determine":[30],"the":[31,43,68,106,114,122,124,129,137,145,151,155,167,170,177,193,197,211,219],"suitability":[32],"of":[33,45,128,150,169,181,221],"using":[34],"stable":[35],"isotope-labeled":[36],"VLCFA":[37,162,222],"patients":[39,182],"these":[41],"metabolism":[44],"22-methyl[23,23,23-2H3]tricosanoic":[46],"(iso-lignoceric)":[47],"acid":[48,153],"was":[49,65,89,103,136],"studied":[50],"rats":[52,76],"vivo":[54,78,179],"and":[55,71,79,109,132,203],"human":[57,82],"skin":[58,83],"fibroblasts":[59,84],"culture.":[61],"The":[62],"deuterated":[63],"iso-VLCFA":[64,202],"degraded":[66],"to":[67],"corresponding":[69,115,198,212],"16-":[70],"18-carbon":[72],"iso-fatty":[73,111],"by":[75,80,192,215],"normal":[81,216],"culture,":[86],"or":[91],"no":[92],"degradation":[93],"peroxisome-deficient":[95],"(Zellweger's":[96],"syndrome)":[97],"fibroblasts,":[98],"indicating":[99],"that":[100,148,161],"its":[101,133],"oxidation":[102],"peroxisomal.":[104],"Neither":[105],"14-,":[107],"20-,":[108],"22-carbon":[110],"nor":[113],"odd-chain":[116],"metabolites":[117],"could":[118],"be":[119,224],"detected.":[120],"In":[121],"rat,":[123],"organ":[125],"containing":[126],"most":[127],"iso-lignoceric":[130],"acid,":[131],"breakdown":[134],"products,":[135],"liver,":[138],"whereas":[139],"negligible":[140],"amounts":[141],"were":[142],"detected":[143],"brain,":[146],"suggesting":[147],"crossed":[154],"blood-brain":[156],"barrier.":[157],"Our":[158],"data":[159],"indicate":[160],"labeled":[163],"deuterium":[165],"at":[166],"omega-position":[168],"are":[173,190,207],"suitable":[174],"derivatives":[175],"for":[176],"investigation":[180],"defects":[184],"beta-oxidation":[187,205],"because":[188],"they":[189],"metabolized":[191],"same":[194],"pathways":[195],"as":[196,201],"n-VLCFA.":[199],"Moreover,":[200],"products":[206],"readily":[208],"separated":[209],"from":[210],"n-fatty":[213],"chromatographic":[217],"procedures,":[218],"can":[223],"more":[225],"precisely":[226],"measured.":[227]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}