{"id":"https://openalex.org/W1982968851","doi":"https://doi.org/10.1111/j.1365-2265.1989.tb01235.x","title":"THE INFLUENCE OF ANTITHYROID DRUGS AND IODINE ON THYROID CELL MHC CLASS II ANTIGEN EXPRESSION","display_name":"THE INFLUENCE OF ANTITHYROID DRUGS AND IODINE ON THYROID CELL MHC CLASS II ANTIGEN EXPRESSION","publication_year":1989,"publication_date":"1989-08-01","ids":{"openalex":"https://openalex.org/W1982968851","doi":"https://doi.org/10.1111/j.1365-2265.1989.tb01235.x","mag":"1982968851","pmid":"https://pubmed.ncbi.nlm.nih.gov/2481575"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-2265.1989.tb01235.x","doi":"https://doi.org/10.1111/j.1365-2265.1989.tb01235.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-2265.1989.tb01235.x","pdf_url":null,"source":{"id":"https://openalex.org/S182143151","display_name":"Clinical Endocrinology","issn_l":"0300-0664","issn":["0300-0664","1365-2265"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066773921","display_name":"Terry F. Davies","orcid":"https://orcid.org/0000-0003-3909-2750","observed_orcids":["https://orcid.org/0000-0003-3909-2750"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"TERRY F. DAVIES","raw_affiliation_strings":["Department of Medicine, Mount Sinai School of Medicine, New York, New York","Department of Medicine, Mount Sinai School of Medicine, New York, New York USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Mount Sinai School of Medicine, New York, New York","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Medicine, Mount Sinai School of Medicine, New York, New York USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077322430","display_name":"CLEMENT YANG","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"CLEMENT YANG","raw_affiliation_strings":["Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA","Department of Medicine, Mount Sinai School of Medicine, New York, New York USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Medicine, Mount Sinai School of Medicine, New York, New York USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064343302","display_name":"Michael Platzer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"MICHAEL PLATZER","raw_affiliation_strings":["Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA","Department of Medicine, Mount Sinai School of Medicine, New York, New York USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Department of Medicine, Mount Sinai School of Medicine, New York, New York USA","institution_ids":["https://openalex.org/I98704320"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5066773921"],"corresponding_institution_ids":["https://openalex.org/I98704320"],"apc_list":{"value":4250,"currency":"USD","value_usd":4250},"apc_paid":null,"fwci":0.273,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.52820392,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"31","issue":"2","first_page":"125","last_page":"135"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antithyroid-drugs","display_name":"antithyroid drugs","score":0.9959999918937683},{"id":"https://openalex.org/keywords/methimazole","display_name":"methimazole","score":0.9779999852180481},{"id":"https://openalex.org/keywords/propylthiouracil","display_name":"propylthiouracil","score":1.0},{"id":"https://openalex.org/keywords/sodium-iodide","display_name":"sodium iodide","score":0.9279999732971191},{"id":"https://openalex.org/keywords/iodide","display_name":"iodide","score":0.859000027179718},{"id":"https://openalex.org/keywords/mhc-class-ii-antigen-expression","display_name":"MHC class II antigen expression","score":0.9580000042915344},{"id":"https://openalex.org/keywords/hla-dr","display_name":"HLA-DR","score":0.9940000176429749},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.8259999752044678},{"id":"https://openalex.org/keywords/thyroid-cells","display_name":"thyroid cells","score":0.6399999856948853},{"id":"https://openalex.org/keywords/t-cell-proliferation","display_name":"T cell proliferation","score":0.49000000953674316},{"id":"https://openalex.org/keywords/frtl-5-cells","display_name":"FRTL-5 cells","score":0.8840000033378601},{"id":"https://openalex.org/keywords/autoimmune-thyroid-disease","display_name":"autoimmune thyroid disease","score":0.8130000233650208},{"id":"https://openalex.org/keywords/experimental-thyroiditis","display_name":"experimental thyroiditis","score":0.8220000267028809},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.9869999885559082}],"concepts":[{"id":"https://openalex.org/C2775960720","wikidata":"https://www.wikidata.org/wiki/Q377342","display_name":"Propylthiouracil","level":3,"score":0.9036072492599487},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6477170586585999},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.6439120173454285},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6346998810768127},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5659360885620117},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.553435742855072},{"id":"https://openalex.org/C180650514","wikidata":"https://www.wikidata.org/wiki/Q419502","display_name":"Thyroid peroxidase","level":3,"score":0.5120866298675537},{"id":"https://openalex.org/C2778814158","wikidata":"https://www.wikidata.org/wiki/Q959350","display_name":"MHC class II","level":4,"score":0.4877846837043762},{"id":"https://openalex.org/C2778696486","wikidata":"https://www.wikidata.org/wiki/Q11835644","display_name":"Thyroiditis","level":3,"score":0.48106813430786133},{"id":"https://openalex.org/C2778835679","wikidata":"https://www.wikidata.org/wiki/Q412228","display_name":"Thyroglobulin","level":3,"score":0.4785516858100891},{"id":"https://openalex.org/C2776652619","wikidata":"https://www.wikidata.org/wiki/Q16483","display_name":"Graves' disease","level":3,"score":0.45034050941467285},{"id":"https://openalex.org/C2776606491","wikidata":"https://www.wikidata.org/wiki/Q1365501","display_name":"Antithyroid agent","level":4,"score":0.4291480481624603},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4105340242385864},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37113329768180847},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3396220803260803},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3251952528953552}],"mesh":[{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000949","descriptor_name":"Histocompatibility Antigens Class II","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006684","descriptor_name":"HLA-DR Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006684","descriptor_name":"HLA-DR Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006684","descriptor_name":"HLA-DR Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007455","descriptor_name":"Iodine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007455","descriptor_name":"Iodine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007455","descriptor_name":"Iodine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012974","descriptor_name":"Sodium Iodide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012974","descriptor_name":"Sodium Iodide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012974","descriptor_name":"Sodium Iodide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013956","descriptor_name":"Antithyroid Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013956","descriptor_name":"Antithyroid Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013956","descriptor_name":"Antithyroid Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013972","descriptor_name":"Thyrotropin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013972","descriptor_name":"Thyrotropin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013972","descriptor_name":"Thyrotropin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1365-2265.1989.tb01235.x","doi":"https://doi.org/10.1111/j.1365-2265.1989.tb01235.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-2265.1989.tb01235.x","pdf_url":null,"source":{"id":"https://openalex.org/S182143151","display_name":"Clinical Endocrinology","issn_l":"0300-0664","issn":["0300-0664","1365-2265"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Endocrinology","raw_type":"journal-article"},{"id":"pmid:2481575","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2481575","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical endocrinology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.6600000262260437,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1021655284","display_name":null,"funder_award_id":"DK35764","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2462762936","display_name":null,"funder_award_id":"DK 28242","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W83534692","https://openalex.org/W117587601","https://openalex.org/W180722681","https://openalex.org/W182951413","https://openalex.org/W1590041785","https://openalex.org/W1972172942","https://openalex.org/W1992758569","https://openalex.org/W1995090750","https://openalex.org/W2005413201","https://openalex.org/W2005496054","https://openalex.org/W2021847833","https://openalex.org/W2026256868","https://openalex.org/W2026390132","https://openalex.org/W2027274130","https://openalex.org/W2029849007","https://openalex.org/W2030326618","https://openalex.org/W2030855756","https://openalex.org/W2039649487","https://openalex.org/W2042113266","https://openalex.org/W2046401733","https://openalex.org/W2047259779","https://openalex.org/W2062115904","https://openalex.org/W2162367555","https://openalex.org/W2165859600","https://openalex.org/W2258594834","https://openalex.org/W2337157164","https://openalex.org/W2408937579","https://openalex.org/W3023465856","https://openalex.org/W3084557416"],"related_works":["https://openalex.org/W2068877328","https://openalex.org/W2117223648","https://openalex.org/W2050473414","https://openalex.org/W2411918257","https://openalex.org/W2116094703","https://openalex.org/W4237215248","https://openalex.org/W2135774957","https://openalex.org/W2004952801","https://openalex.org/W2073791878","https://openalex.org/W2080781160"],"abstract_inverted_index":{"We":[0],"have":[1,189],"investigated":[2],"the":[3,15,83,95,122,144,167,171],"influence":[4,53,105,174,195],"of":[5,17,57,86,94,125,158,170,175],"antithyroid":[6,66,176],"drugs":[7,50,67,177],"(methimazole":[8],"and":[9,11,27,33,182,192,200],"propylthiouracil)":[10],"sodium":[12],"iodide":[13,119],"on":[14,54,73,106,196],"expression":[16,24,114,124],"major":[18],"histocompatibility":[19],"(MHC)":[20],"class":[21,39,58,88,111,127],"II":[22,40,59,89,112,128],"antigen":[23,42,90,113,201],"in":[25,43,61,130,178],"human":[26,45,107],"rat":[28,133,145],"thyroid":[29,46,74,108,134,146,180,197],"cells.":[30],"While":[31],"methimazole":[32],"propylthiouracil":[34],"significantly":[35,120],"inhibited":[36,121],"lectin-induced":[37],"MHC":[38,87,110,126],"(HLA-DR)":[41],"crude":[44],"monolayer":[47,75],"preparations":[48],"these":[49],"had":[51,69,102],"no":[52,103],"gamma-interferon":[55,97],"induction":[56,85],"antigens":[60,129],"similar":[62],"cell":[63,109,135,147,198],"preparations.":[64],"Hence,":[65],"probably":[68],"a":[70,131,190],"direct":[71,104],"effect":[72,82],"T":[76],"cells":[77,140],"which":[78],"are":[79],"known":[80],"to":[81,153,166],"lectin":[84],"via":[91,156],"T-cell":[92],"secretion":[93],"cytokine,":[96],"(IF).":[98],"Sodium":[99],"iodide,":[100],"similarly,":[101],"induced":[115],"by":[116],"gamma-IF.":[117],"However,":[118],"gamma-IF-induced":[123],"proliferating":[132],"clone":[136,148],"derived":[137],"from":[138],"FRTL-5":[139],"(clone":[141],"1B-6).":[142],"In":[143,185],"this":[149],"antagonistic":[150],"action":[151],"appeared":[152],"be":[154],"exerted":[155],"inhibition":[157],"TSH-induced":[159],"proliferation.":[160],"These":[161],"data":[162],"add":[163],"further":[164],"support":[165],"multifactorial":[168],"nature":[169],"profound":[172],"immunosuppressive":[173],"autoimmune":[179],"disease":[181],"experimental":[183],"thyroiditis.":[184],"contrast,":[186],"iodides":[187],"may":[188],"major,":[191],"often":[193],"overlooked,":[194],"proliferation":[199],"expression.":[202]},"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-10T00:00:00"}