{"id":"https://openalex.org/W1982523908","doi":null,"title":"Umbilical cord blood: current status & promise for the future.","display_name":"Umbilical cord blood: current status & promise for the future.","publication_year":2011,"publication_date":"2011-09-01","ids":{"openalex":"https://openalex.org/W1982523908","mag":"1982523908","pmid":"https://pubmed.ncbi.nlm.nih.gov/21985808","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3193706"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3193706","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3193706/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3193706/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian J Med Res","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3193706/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061426484","display_name":"David H. McKenna","orcid":"https://orcid.org/0000-0001-8734-0996","observed_orcids":["https://orcid.org/0000-0001-8734-0996"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David McKenna","raw_affiliation_strings":["Foundation for Research in Genetics & Endocrinology, Ahmedabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Foundation for Research in Genetics & Endocrinology, Ahmedabad, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005522975","display_name":"Jayesh J. Sheth","orcid":"https://orcid.org/0000-0001-5936-5192","observed_orcids":["https://orcid.org/0000-0001-5936-5192"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jayesh Sheth","raw_affiliation_strings":["Foundation for Research in Genetics and Endocrinology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Foundation for Research in Genetics and Endocrinology","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.128,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.91877827,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"134","issue":null,"first_page":"261","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13417","display_name":"Biomedical Ethics and Regulation","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2910","display_name":"Issues, ethics and legal aspects"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/umbilical-cord-blood","display_name":"umbilical cord blood","score":1.0},{"id":"https://openalex.org/keywords/hematopoietic-stem-cells","display_name":"hematopoietic stem cells","score":0.9419999718666077},{"id":"https://openalex.org/keywords/hematopoietic-stem-cell-transplantation","display_name":"hematopoietic stem cell transplantation","score":0.8820000290870667},{"id":"https://openalex.org/keywords/cord-blood-banking","display_name":"cord blood banking","score":0.9120000004768372},{"id":"https://openalex.org/keywords/regulatory-oversight","display_name":"regulatory oversight","score":0.6370000243186951},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.7919999957084656},{"id":"https://openalex.org/keywords/tissue-engineering","display_name":"tissue engineering","score":0.9580000042915344},{"id":"https://openalex.org/keywords/regenerative-medicine","display_name":"regenerative medicine","score":1.0},{"id":"https://openalex.org/keywords/ethical-issues","display_name":"ethical considerations","score":0.6510000228881836},{"id":"https://openalex.org/keywords/public-policy","display_name":"public policy","score":0.6710000038146973},{"id":"https://openalex.org/keywords/india","display_name":"India","score":0.42500001192092896}],"concepts":[{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.672456681728363},{"id":"https://openalex.org/C2778137410","wikidata":"https://www.wikidata.org/wiki/Q2732820","display_name":"Government (linguistics)","level":2,"score":0.5680016875267029},{"id":"https://openalex.org/C61521584","wikidata":"https://www.wikidata.org/wiki/Q705899","display_name":"Accreditation","level":2,"score":0.5675719976425171},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5563263893127441},{"id":"https://openalex.org/C2776955114","wikidata":"https://www.wikidata.org/wiki/Q172563","display_name":"Umbilical cord","level":2,"score":0.5556120872497559},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5099145174026489},{"id":"https://openalex.org/C2780914630","wikidata":"https://www.wikidata.org/wiki/Q914952","display_name":"Cord blood","level":2,"score":0.49461600184440613},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.48956283926963806},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.43126043677330017},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4115757346153259},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.37944912910461426},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3675333857536316},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18420016765594482},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1216595470905304},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.09732919931411743},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000094902","descriptor_name":"Blood Banking","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D001771","descriptor_name":"Blood Banks","qualifier_ui":"Q000331","qualifier_name":"legislation & jurisprudence","is_major_topic":false},{"descriptor_ui":"D001771","descriptor_name":"Blood Banks","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D001771","descriptor_name":"Blood Banks","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D005312","descriptor_name":"Fetal Blood","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036101","descriptor_name":"Cord Blood Stem Cell Transplantation","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D036101","descriptor_name":"Cord Blood Stem Cell Transplantation","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:3193706","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3193706/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3193706/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian J Med Res","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:2200181","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3193706","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:21985808","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21985808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Indian journal of medical research","raw_type":"Journal Article"},{"id":"mag:1982523908","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21985808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3193706","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3193706/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3193706/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian J Med Res","raw_type":"Text"},"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309636","display_name":"University of Minnesota","ror":"https://ror.org/03grvy078"},{"id":"https://openalex.org/F4320325506","display_name":"Gujarat Cancer and Research Institute","ror":"https://ror.org/015bxyv30"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1982523908.pdf","grobid_xml":"https://content.openalex.org/works/W1982523908.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W174595874","https://openalex.org/W1966545752","https://openalex.org/W1975255476","https://openalex.org/W1977685637","https://openalex.org/W1986654721","https://openalex.org/W1994891102","https://openalex.org/W1996852376","https://openalex.org/W1998241587","https://openalex.org/W1998368165","https://openalex.org/W2002650695","https://openalex.org/W2028860972","https://openalex.org/W2030370150","https://openalex.org/W2042254458","https://openalex.org/W2058451719","https://openalex.org/W2060271699","https://openalex.org/W2061997665","https://openalex.org/W2069209063","https://openalex.org/W2071941012","https://openalex.org/W2074261411","https://openalex.org/W2081367598","https://openalex.org/W2084040058","https://openalex.org/W2093321453","https://openalex.org/W2093416386","https://openalex.org/W2101219010","https://openalex.org/W2105998351","https://openalex.org/W2122086247","https://openalex.org/W2131199757","https://openalex.org/W2133971325","https://openalex.org/W2135067231","https://openalex.org/W2141952395","https://openalex.org/W2143182768","https://openalex.org/W2153531211","https://openalex.org/W2157939115","https://openalex.org/W2159637780","https://openalex.org/W2159672247","https://openalex.org/W2160666689","https://openalex.org/W2162602791","https://openalex.org/W2262982217","https://openalex.org/W2332363829","https://openalex.org/W2412910867","https://openalex.org/W2475379673","https://openalex.org/W2588203075","https://openalex.org/W2766221074","https://openalex.org/W4291673990"],"related_works":["https://openalex.org/W4245463006","https://openalex.org/W2757632820","https://openalex.org/W1870328124","https://openalex.org/W2058239711","https://openalex.org/W7154962823","https://openalex.org/W3110278652","https://openalex.org/W1889879633","https://openalex.org/W2576680630","https://openalex.org/W2347286090","https://openalex.org/W1979678460"],"abstract_inverted_index":{"Umbilical":[0],"cord":[1],"blood":[2],"(UCB)":[3],"has":[4,46,78],"been":[5],"shown":[6],"to":[7,54,84,134,163],"be":[8],"a":[9,34],"suitable":[10],"source":[11],"of":[12,25,31,37,67,86,95,104,124,156,183],"haematopoietic":[13,18,62],"stem":[14],"cells":[15],"(HSCs)":[16],"for":[17,58,170],"reconstitution.":[19],"An":[20],"increase":[21],"in":[22,33,101,129,143,151,179],"the":[23,42,110,157,180],"number":[24],"UCB":[26,44,57,68,76,149,164],"transplants":[27],"indicates":[28],"an":[29],"expansion":[30],"utility":[32],"broad":[35],"spectrum":[36],"disease":[38],"conditions.":[39],"Along":[40],"with":[41,80,109],"advantages,":[43],"also":[45],"limitations,":[47],"and":[48,73,89,100,117,137,166,175,185],"hence":[49],"several":[50],"investigators":[51],"are":[52,107,121,178],"working":[53],"further":[55],"optimize":[56],"this":[59],"use.":[60],"Beyond":[61],"transplantation,":[63],"additional":[64],"potential":[65],"applications":[66],"include":[69],"immunotherapy,":[70],"tissue":[71],"engineering":[72],"regenerative":[74],"medicine.":[75],"banking":[77,165],"improved":[79],"time":[81],"largely":[82],"due":[83],"involvement":[85],"professional":[87],"organizations":[88,97],"their":[90],"published":[91],"standards.":[92],"However,":[93],"accreditation":[94],"these":[96],"remains":[98],"voluntary,":[99],"India":[102],"three":[103],"ten":[105],"banks":[106],"public":[108,116],"remaining":[111],"being":[112],"private.":[113],"Only":[114],"one":[115,118],"private":[119],"bank":[120],"American":[122],"Association":[123],"Blood":[125],"Banks":[126],"(AABB)":[127],"accredited":[128],"India.":[130],"Government":[131],"agencies":[132],"need":[133],"provide":[135],"regulatory":[136],"safety":[138],"oversight,":[139],"which":[140],"is":[141,150],"lacking":[142],"serveral":[144],"countries.":[145],"Public":[146],"policy":[147],"regarding":[148],"its":[152],"infancy":[153],"throughout":[154],"most":[155],"world.":[158],"Ethical":[159],"issues,":[160],"including":[161],"access":[162],"use":[167],"as":[168],"therapy":[169],"diseases":[171],"other":[172],"than":[173],"haematological":[174],"metabolic":[176],"disorders":[177],"early":[181],"phase":[182],"trials":[184],"remain":[186],"speculative.":[187]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}