{"id":"https://openalex.org/W1982481323","doi":"https://doi.org/10.1093/nar/gkj063","title":"The PROSITE database","display_name":"The PROSITE database","publication_year":2005,"publication_date":"2005-12-28","ids":{"openalex":"https://openalex.org/W1982481323","doi":"https://doi.org/10.1093/nar/gkj063","mag":"1982481323","pmid":"https://pubmed.ncbi.nlm.nih.gov/16381852","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1347426"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkj063","doi":"https://doi.org/10.1093/nar/gkj063","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkj063","pdf_url":"https://academic.oup.com/nar/article-pdf/34/suppl_1/D227/3924681/gkj063.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/34/suppl_1/D227/3924681/gkj063.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058665636","display_name":"Nicolas Hulo","orcid":"https://orcid.org/0000-0003-2640-636X","observed_orcids":["https://orcid.org/0000-0003-2640-636X"]},"institutions":[{"id":"https://openalex.org/I12708293","display_name":"SIB Swiss Institute of Bioinformatics","ror":"https://ror.org/002n09z45","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I12708293"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"N. Hulo","raw_affiliation_strings":["Swiss Institute of Bioinformatics (SIB), Centre Medical Universitaire, 1 rue Michel Servet, 1211 Geneva 4, Switzerland. Nicolas.Hulo@isb-sib.ch"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Swiss Institute of Bioinformatics (SIB), Centre Medical Universitaire, 1 rue Michel Servet, 1211 Geneva 4, Switzerland. Nicolas.Hulo@isb-sib.ch","institution_ids":["https://openalex.org/I12708293"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5058665636"],"corresponding_institution_ids":["https://openalex.org/I12708293"],"apc_list":{"value":3992,"currency":"USD","value_usd":3992},"apc_paid":{"value":3992,"currency":"USD","value_usd":3992},"fwci":31.2827,"has_fulltext":true,"cited_by_count":993,"citation_normalized_percentile":{"value":0.99933552,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"34","issue":"90001","first_page":"D227","last_page":"D230"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.7045999765396118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.7045999765396118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.16380000114440918,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.03669999912381172,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prosite","display_name":"PROSITE","score":0.9480000138282776},{"id":"https://openalex.org/keywords/proteomic-signatures","display_name":"proteomic signatures","score":0.6549999713897705},{"id":"https://openalex.org/keywords/protein-profile","display_name":"protein profile","score":0.5640000104904175},{"id":"https://openalex.org/keywords/protein-domains","display_name":"protein domains","score":0.875},{"id":"https://openalex.org/keywords/protein-families","display_name":"protein families","score":0.7580000162124634},{"id":"https://openalex.org/keywords/functional-sites","display_name":"functional sites","score":0.8149999976158142}],"concepts":[{"id":"https://openalex.org/C202264299","wikidata":"https://www.wikidata.org/wiki/Q905695","display_name":"UniProt","level":3,"score":0.8867250084877014},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7136439085006714},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.5905811190605164},{"id":"https://openalex.org/C56666940","wikidata":"https://www.wikidata.org/wiki/Q788790","display_name":"Documentation","level":2,"score":0.5598282814025879},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.23713678121566772},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0787959098815918},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06993690133094788},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":8,"locations":[{"id":"doi:10.1093/nar/gkj063","doi":"https://doi.org/10.1093/nar/gkj063","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkj063","pdf_url":"https://academic.oup.com/nar/article-pdf/34/suppl_1/D227/3924681/gkj063.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:156881","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC1347426","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:16381852","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16381852","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1347426","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1347426/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmh:oai:unige.ch:unige:36343","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:36343","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ISSN: 0305-1048","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.109.3883","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.109.3883","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://nar.oxfordjournals.org/cgi/reprint/34/suppl_1/D227.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.277.4638","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.277.4638","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/ad/ea/Nucleic_Acids_Res_2006_Jan_1_34(Database_issue)_D227-D230.tar.gz","raw_type":"text"},{"id":"pmh:oai:unige.ch:aou:unige:36343","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:36343","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 0305-1048","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/nar/gkj063","doi":"https://doi.org/10.1093/nar/gkj063","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkj063","pdf_url":"https://academic.oup.com/nar/article-pdf/34/suppl_1/D227/3924681/gkj063.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1982481323.pdf","grobid_xml":"https://content.openalex.org/works/W1982481323.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W1981095206","https://openalex.org/W1982028980","https://openalex.org/W2038988292","https://openalex.org/W2093842873","https://openalex.org/W2126975650","https://openalex.org/W2127648442","https://openalex.org/W2141773967","https://openalex.org/W2160717157"],"related_works":["https://openalex.org/W7097814721","https://openalex.org/W2126975650","https://openalex.org/W2916193864","https://openalex.org/W2915190566","https://openalex.org/W7206871922","https://openalex.org/W2143173841","https://openalex.org/W2155744824","https://openalex.org/W2127648442","https://openalex.org/W7100354329","https://openalex.org/W7096271570"],"abstract_inverted_index":{"The":[0,43,81,130],"PROSITE":[1,44,85,128],"database":[2,45,131],"consists":[3],"of":[4,8,52,84,88,114,119],"a":[5,24,50,124,127],"large":[6],"collection":[7],"biologically":[9],"meaningful":[10],"signatures":[11],"that":[12,26,54],"are":[13],"described":[14],"as":[15],"patterns":[16,94],"or":[17,36],"profiles.":[18],"Each":[19],"signature":[20],"is":[21,46,132],"linked":[22],"to":[23,77,126],"documentation":[25,69],"provides":[27],"useful":[28],"biological":[29],"information":[30,59],"on":[31],"the":[32,41,64,68,71,100],"protein":[33],"family,":[34],"domain":[35],"functional":[37],"site":[38],"identified":[39],"by":[40,49],"signature.":[42],"now":[47,112],"complemented":[48],"series":[51],"rules":[53],"can":[55],"give":[56],"more":[57,79,104],"precise":[58],"about":[60],"specific":[61],"residues.":[62],"During":[63],"last":[65],"2":[66,102],"years,":[67],"and":[70,95,111],"ScanProsite":[72],"web":[73],"pages":[74],"were":[75],"redesigned":[76],"add":[78],"functionalities.":[80],"latest":[82],"version":[83],"(release":[86,117],"19.11":[87],"September":[89,120],"27,":[90,121],"2005)":[91,122],"contains":[92],"1329":[93],"552":[96],"profile":[97],"entries.":[98],"Over":[99],"past":[101],"years":[103],"than":[105],"200":[106],"domains":[107],"have":[108,123],"been":[109],"added,":[110],"52%":[113],"UniProtKB/Swiss-Prot":[115],"entries":[116],"48.1":[118],"cross-reference":[125],"entry.":[129],"accessible":[133],"at":[134],"http://www.expasy.org/prosite/.":[135]},"counts_by_year":[{"year":2026,"cited_by_count":23},{"year":2025,"cited_by_count":35},{"year":2024,"cited_by_count":32},{"year":2023,"cited_by_count":45},{"year":2022,"cited_by_count":34},{"year":2021,"cited_by_count":43},{"year":2020,"cited_by_count":29},{"year":2019,"cited_by_count":24},{"year":2018,"cited_by_count":32},{"year":2017,"cited_by_count":18},{"year":2016,"cited_by_count":21},{"year":2015,"cited_by_count":18},{"year":2014,"cited_by_count":33},{"year":2013,"cited_by_count":32},{"year":2012,"cited_by_count":47}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}