{"id":"https://openalex.org/W1982300925","doi":"https://doi.org/10.1097/00006534-199606000-00014","title":"Autoradiographic Analysis of Expanded Skeletal Muscle in Rats","display_name":"Autoradiographic Analysis of Expanded Skeletal Muscle in Rats","publication_year":1996,"publication_date":"1996-06-01","ids":{"openalex":"https://openalex.org/W1982300925","doi":"https://doi.org/10.1097/00006534-199606000-00014","mag":"1982300925","pmid":"https://pubmed.ncbi.nlm.nih.gov/8643724"},"language":"en","primary_location":{"id":"doi:10.1097/00006534-199606000-00014","doi":"https://doi.org/10.1097/00006534-199606000-00014","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00006534-199606000-00014","pdf_url":null,"source":{"id":"https://openalex.org/S100736837","display_name":"Plastic & Reconstructive Surgery","issn_l":"0032-1052","issn":["0032-1052","1076-5751","1529-4242"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and Reconstructive Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075149323","display_name":"A. Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1293502524","display_name":"Loma Linda University Medical Center","ror":"https://ror.org/03et1qs84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1293502524"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alex K. Kim","raw_affiliation_strings":["Division of Plastic and Reconstructive Surgery","Loma Linda, Calif","Los Angeles, Calif. 90033","University of Southern California","the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994; revised June 15, 1995","revised June 15, 1995","the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Plastic and Reconstructive Surgery","institution_ids":[]},{"raw_affiliation_string":"Loma Linda, Calif","institution_ids":[]},{"raw_affiliation_string":"Los Angeles, Calif. 90033","institution_ids":[]},{"raw_affiliation_string":"University of Southern California","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994; revised June 15, 1995","institution_ids":["https://openalex.org/I1293502524"]},{"raw_affiliation_string":"revised June 15, 1995","institution_ids":[]},{"raw_affiliation_string":"the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994","institution_ids":["https://openalex.org/I1293502524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037474578","display_name":"Kerby C. Oberg","orcid":"https://orcid.org/0000-0002-1241-4273","observed_orcids":["https://orcid.org/0000-0002-1241-4273"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1293502524","display_name":"Loma Linda University Medical Center","ror":"https://ror.org/03et1qs84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1293502524"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kerby Oberg","raw_affiliation_strings":["Division of Plastic and Reconstructive Surgery","Loma Linda, Calif","Los Angeles, Calif. 90033","University of Southern California","the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994; revised June 15, 1995","revised June 15, 1995","the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Plastic and Reconstructive Surgery","institution_ids":[]},{"raw_affiliation_string":"Loma Linda, Calif","institution_ids":[]},{"raw_affiliation_string":"Los Angeles, Calif. 90033","institution_ids":[]},{"raw_affiliation_string":"University of Southern California","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994; revised June 15, 1995","institution_ids":["https://openalex.org/I1293502524"]},{"raw_affiliation_string":"revised June 15, 1995","institution_ids":[]},{"raw_affiliation_string":"the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994","institution_ids":["https://openalex.org/I1293502524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085647163","display_name":"Gordon G. Power","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1293502524","display_name":"Loma Linda University Medical Center","ror":"https://ror.org/03et1qs84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1293502524"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gordon G. Power","raw_affiliation_strings":["Division of Plastic and Reconstructive Surgery","Loma Linda, Calif","Los Angeles, Calif. 90033","University of Southern California","the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994; revised June 15, 1995","revised June 15, 1995","the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Plastic and Reconstructive Surgery","institution_ids":[]},{"raw_affiliation_string":"Loma Linda, Calif","institution_ids":[]},{"raw_affiliation_string":"Los Angeles, Calif. 90033","institution_ids":[]},{"raw_affiliation_string":"University of Southern California","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994; revised June 15, 1995","institution_ids":["https://openalex.org/I1293502524"]},{"raw_affiliation_string":"revised June 15, 1995","institution_ids":[]},{"raw_affiliation_string":"the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994","institution_ids":["https://openalex.org/I1293502524"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051263617","display_name":"Robert A. Hardesty","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I1293502524","display_name":"Loma Linda University Medical Center","ror":"https://ror.org/03et1qs84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1293502524"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Hardesty","raw_affiliation_strings":["Division of Plastic and Reconstructive Surgery","Loma Linda, Calif","Los Angeles, Calif. 90033","University of Southern California","the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994; revised June 15, 1995","revised June 15, 1995","the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Plastic and Reconstructive Surgery","institution_ids":[]},{"raw_affiliation_string":"Loma Linda, Calif","institution_ids":[]},{"raw_affiliation_string":"Los Angeles, Calif. 90033","institution_ids":[]},{"raw_affiliation_string":"University of Southern California","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994; revised June 15, 1995","institution_ids":["https://openalex.org/I1293502524"]},{"raw_affiliation_string":"revised June 15, 1995","institution_ids":[]},{"raw_affiliation_string":"the Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Pathology and Human Anatomy, and the Center for Perinatal Biology at the Loma Linda University Medical Center. Received for publication December 7, 1994","institution_ids":["https://openalex.org/I1293502524"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.08544304,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"97","issue":"7","first_page":"1411","last_page":"1415"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.8335000276565552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.8335000276565552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10599","display_name":"Reconstructive Surgery and Microvascular Techniques","score":0.048900000751018524,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.020400000736117363,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tissue-expanders","display_name":"tissue expanders","score":0.8700000047683716},{"id":"https://openalex.org/keywords/muscle-regeneration","display_name":"muscle regeneration","score":0.35899999737739563},{"id":"https://openalex.org/keywords/reconstructive-surgery","display_name":"reconstructive surgery","score":0.7540000081062317}],"concepts":[{"id":"https://openalex.org/C68731436","wikidata":"https://www.wikidata.org/wiki/Q1337087","display_name":"Sarcomere","level":3,"score":0.9879571199417114},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.7355000972747803},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6376894116401672},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.5855280160903931},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.43822917342185974},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.313262403011322},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19983357191085815},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19204610586166382},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.13487747311592102}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001345","descriptor_name":"Autoradiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012518","descriptor_name":"Sarcomeres","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015626","descriptor_name":"Tissue Expansion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00006534-199606000-00014","doi":"https://doi.org/10.1097/00006534-199606000-00014","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00006534-199606000-00014","pdf_url":null,"source":{"id":"https://openalex.org/S100736837","display_name":"Plastic & Reconstructive Surgery","issn_l":"0032-1052","issn":["0032-1052","1076-5751","1529-4242"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and Reconstructive Surgery","raw_type":"journal-article"},{"id":"pmid:8643724","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8643724","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and reconstructive surgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W131344880","https://openalex.org/W251737154","https://openalex.org/W1981465139","https://openalex.org/W1986383449","https://openalex.org/W2079480888","https://openalex.org/W2087463224","https://openalex.org/W2345224831"],"related_works":["https://openalex.org/W1981465139","https://openalex.org/W7099618035","https://openalex.org/W2076637715","https://openalex.org/W815229133","https://openalex.org/W2078533408","https://openalex.org/W2509801226","https://openalex.org/W2040446253","https://openalex.org/W1990812823","https://openalex.org/W2345224831","https://openalex.org/W7163831882"],"abstract_inverted_index":{"The":[0,141,182],"use":[1],"of":[2,31,42,61,84,97,117,123,126,143,177,184,209,219],"tissue":[3],"expanders":[4],"in":[5,39,50,75,110,135,173],"reconstructive":[6],"surgery":[7],"is":[8,18,34,49,187,195],"now":[9],"common.":[10],"However,":[11,189],"the":[12,40,67,81,95,105,111,127,138,144,151,162,174,178,210],"physiologic":[13],"mechanisms":[14],"by":[15,36,104],"which":[16],"expansion":[17,30,96],"achieved":[19],"are":[20],"not":[21],"well":[22],"understood.":[23],"A":[24],"recent":[25],"study":[26],"demonstrated":[27,130],"that":[28,59,192],"rapid":[29],"skeletal":[32,98,180],"muscle":[33,46,106,129,211],"accompanied":[35],"an":[37,216],"increase":[38,134],"number":[41],"sarcomeres":[43,76],"within":[44,137],"a":[45,131,147,168,207],"fiber.":[47],"This":[48],"contrast":[51],"to":[52,66,79,199,202,206,215],"previous":[53],"animal":[54],"studies":[55],"whose":[56],"results":[57],"suggested":[58],"synthesis":[60,172,194],"sarcomere":[62,85,171,193],"units":[63],"was":[64,90,101],"limited":[65],"perinatal":[68],"period.":[69],"To":[70],"further":[71],"investigate":[72],"potential":[73],"increases":[74],"and":[77,108,197],"attempt":[78],"localize":[80],"active":[82],"sites":[83],"synthesis,":[86],"labeled":[87],"adenosine":[88],"(3H)":[89],"injected":[91],"into":[92],"rats":[93],"during":[94],"muscle.":[99,140,181],"Adenosine":[100],"taken":[102],"up":[103],"fibers":[107,212],"incorporated":[109],"newly":[112],"formed":[113],"actin":[114],"as":[115],"part":[116],"light":[118],"chains.":[119],"An":[120],"autoradiographic":[121],"analysis":[122],"histologic":[124],"sections":[125,153],"expanded":[128,139],"statistically":[132],"significant":[133],"radioactivity":[136,145],"distribution":[142],"followed":[146],"proximal-to-distal":[148],"gradient,":[149],"with":[150],"proximal":[152,175],"exhibiting":[154],"more":[155],"than":[156,161,214],"50":[157],"percent":[158],"greater":[159],"activity":[160],"distal":[163],"aspects.":[164],"These":[165],"data":[166],"suggest":[167],"preference":[169],"for":[170],"portion":[176,208],"expanding":[179],"significance":[183],"this":[185],"finding":[186],"uncertain.":[188],"we":[190],"suspect":[191],"tension-dependent":[196],"likely":[198],"be":[200],"related":[201],"local":[203],"tension":[204],"applied":[205],"rather":[213],"anatomic":[217],"site":[218],"preference.":[220]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}