{"id":"https://openalex.org/W1982170652","doi":"https://doi.org/10.3109/13685538.2013.773305","title":"Low-intermediate dose testosterone replacement therapy by different pharmaceutical preparations improves frailty score in elderly hypogonadal hyperglycaemic patients","display_name":"Low-intermediate dose testosterone replacement therapy by different pharmaceutical preparations improves frailty score in elderly hypogonadal hyperglycaemic patients","publication_year":2013,"publication_date":"2013-03-21","ids":{"openalex":"https://openalex.org/W1982170652","doi":"https://doi.org/10.3109/13685538.2013.773305","mag":"1982170652","pmid":"https://pubmed.ncbi.nlm.nih.gov/23517433"},"language":"en","primary_location":{"id":"doi:10.3109/13685538.2013.773305","doi":"https://doi.org/10.3109/13685538.2013.773305","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13685538.2013.773305","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685538.2013.773305?needAccess=true&role=button","source":{"id":"https://openalex.org/S172622653","display_name":"The Aging Male","issn_l":"1368-5538","issn":["1368-5538","1473-0790"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Male","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685538.2013.773305?needAccess=true&role=button","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042464990","display_name":"Felice Strollo","orcid":"https://orcid.org/0000-0001-8917-5314","observed_orcids":["https://orcid.org/0000-0001-8917-5314"]},"institutions":[{"id":"https://openalex.org/I4210161542","display_name":"Istituto Nazionale di Riposo e Cura per Anziani","ror":"https://ror.org/057aq1y25","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210161542"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Felice Strollo","raw_affiliation_strings":["Endocrine and Metabolic Unit, INRCA, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine and Metabolic Unit, INRCA, Rome, Italy","institution_ids":["https://openalex.org/I4210161542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064877098","display_name":"Giovanna Strollo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giovanna Strollo","raw_affiliation_strings":["Endocrinology and Diabetology Unit, FBF S. Peter\u2019s Hospital RomeItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrinology and Diabetology Unit, FBF S. Peter\u2019s Hospital RomeItaly","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012984452","display_name":"Massimo Mor\u00e8","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161542","display_name":"Istituto Nazionale di Riposo e Cura per Anziani","ror":"https://ror.org/057aq1y25","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210161542"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimo Mor\u00e8","raw_affiliation_strings":["Endocrine and Metabolic Unit, INRCA RomeItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine and Metabolic Unit, INRCA RomeItaly","institution_ids":["https://openalex.org/I4210161542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052124556","display_name":"Paolo Magni","orcid":"https://orcid.org/0000-0002-2254-8881","observed_orcids":["https://orcid.org/0000-0002-2254-8881"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Magni","raw_affiliation_strings":["Department of Pharmacological and Biomedical Sciences, Universit\u00e0 degli Studi di Milano MilanItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacological and Biomedical Sciences, Universit\u00e0 degli Studi di Milano MilanItaly","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045141716","display_name":"Chiara Macchi","orcid":"https://orcid.org/0000-0002-5919-989X","observed_orcids":["https://orcid.org/0000-0002-5919-989X"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Chiara Macchi","raw_affiliation_strings":["Department of Pharmacological and Biomedical Sciences, Universit\u00e0 degli Studi di Milano MilanItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacological and Biomedical Sciences, Universit\u00e0 degli Studi di Milano MilanItaly","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050687594","display_name":"Maria Angela Masini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Angela Masini","raw_affiliation_strings":["DipTeRis, University of Genoa GenoaItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DipTeRis, University of Genoa GenoaItaly","institution_ids":["https://openalex.org/I83816512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016153245","display_name":"Iarba Carucci","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161542","display_name":"Istituto Nazionale di Riposo e Cura per Anziani","ror":"https://ror.org/057aq1y25","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210161542"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Iarba Carucci","raw_affiliation_strings":["Endocrine and Metabolic Unit, INRCA RomeItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrine and Metabolic Unit, INRCA RomeItaly","institution_ids":["https://openalex.org/I4210161542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070271118","display_name":"Fabio Celotti","orcid":"https://orcid.org/0000-0002-8301-5245","observed_orcids":["https://orcid.org/0000-0002-8301-5245"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Fabio Celotti","raw_affiliation_strings":["Department of Pharmacological and Biomedical Sciences, Universit\u00e0 degli Studi di Milano MilanItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacological and Biomedical Sciences, Universit\u00e0 degli Studi di Milano MilanItaly","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022387451","display_name":"Massimiliano Ruscica","orcid":"https://orcid.org/0000-0002-0195-7061","observed_orcids":["https://orcid.org/0000-0002-0195-7061"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimiliano Ruscica","raw_affiliation_strings":["Department of Pharmacological and Biomedical Sciences, Universit\u00e0 degli Studi di Milano MilanItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacological and Biomedical Sciences, Universit\u00e0 degli Studi di Milano MilanItaly","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056293872","display_name":"Sandro Gentile","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sandro Gentile","raw_affiliation_strings":["Clinical and Experimental Medicine Dept, 2nd University of Naples NaplesItaly"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Experimental Medicine Dept, 2nd University of Naples NaplesItaly","institution_ids":["https://openalex.org/I197809005"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5070271118"],"corresponding_institution_ids":["https://openalex.org/I189158943"],"apc_list":{"value":2085,"currency":"GBP","value_usd":2557},"apc_paid":null,"fwci":4.4575,"has_fulltext":true,"cited_by_count":35,"citation_normalized_percentile":{"value":0.94852347,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"16","issue":"2","first_page":"33","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/testosterone-replacement-therapy","display_name":"testosterone replacement therapy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/andropause","display_name":"andropause","score":0.9739999771118164},{"id":"https://openalex.org/keywords/frailty","display_name":"frailty","score":0.8299999833106995},{"id":"https://openalex.org/keywords/impaired-fasting-glucose","display_name":"impaired fasting glucose","score":0.7620000243186951},{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.7770000100135803},{"id":"https://openalex.org/keywords/transdermal-testosterone","display_name":"transdermal testosterone","score":0.996999979019165},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9599999785423279},{"id":"https://openalex.org/keywords/older-men","display_name":"older men","score":0.7310000061988831},{"id":"https://openalex.org/keywords/overweight","display_name":"overweight","score":0.6290000081062317},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.5879999995231628},{"id":"https://openalex.org/keywords/handgrip-strength","display_name":"grip strength","score":0.8629999756813049},{"id":"https://openalex.org/keywords/walking-speed","display_name":"walking speed","score":0.640999972820282},{"id":"https://openalex.org/keywords/prostate-specific-antigen","display_name":"prostate-specific antigen","score":0.6930000185966492},{"id":"https://openalex.org/keywords/hemoglobin","display_name":"hemoglobin","score":0.8019999861717224}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9461879730224609},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6579622030258179},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.6219412684440613},{"id":"https://openalex.org/C2776193436","wikidata":"https://www.wikidata.org/wiki/Q236232","display_name":"Waist","level":3,"score":0.6008106470108032},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.5789364576339722},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.5543535947799683},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.48311755061149597},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.44949716329574585},{"id":"https://openalex.org/C2777433710","wikidata":"https://www.wikidata.org/wiki/Q5609571","display_name":"Grip strength","level":2,"score":0.43709880113601685},{"id":"https://openalex.org/C61427482","wikidata":"https://www.wikidata.org/wiki/Q6656244","display_name":"Anthropometry","level":2,"score":0.4222556948661804},{"id":"https://openalex.org/C2778535154","wikidata":"https://www.wikidata.org/wiki/Q5889863","display_name":"Homeostatic model assessment","level":4,"score":0.41889262199401855},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.30242833495140076},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.1907811462879181}],"mesh":[{"descriptor_ui":"D000279","descriptor_name":"Administration, Cutaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006943","descriptor_name":"Hyperglycemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006943","descriptor_name":"Hyperglycemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007006","descriptor_name":"Hypogonadism","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D007006","descriptor_name":"Hypogonadism","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017430","descriptor_name":"Prostate-Specific Antigen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020249","descriptor_name":"Hormone Replacement Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D053580","descriptor_name":"Muscle Strength","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D053580","descriptor_name":"Muscle Strength","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3109/13685538.2013.773305","doi":"https://doi.org/10.3109/13685538.2013.773305","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13685538.2013.773305","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685538.2013.773305?needAccess=true&role=button","source":{"id":"https://openalex.org/S172622653","display_name":"The Aging Male","issn_l":"1368-5538","issn":["1368-5538","1473-0790"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Male","raw_type":"journal-article"},{"id":"pmid:23517433","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23517433","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The aging male : the official journal of the International Society for the Study of the Aging Male","raw_type":"Comparative Study"},{"id":"pmh:oai:iris.unicampania.it:11591/191974","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11591/191974","pdf_url":null,"source":{"id":"https://openalex.org/S7407055255","display_name":"Archivio Istituzionale della Ricerca - Universit\u00e0 degli Studi della Campania \"Luigi Vanvitelli\"","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3109/13685538.2013.773305","doi":"https://doi.org/10.3109/13685538.2013.773305","is_oa":true,"landing_page_url":"https://doi.org/10.3109/13685538.2013.773305","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/13685538.2013.773305?needAccess=true&role=button","source":{"id":"https://openalex.org/S172622653","display_name":"The Aging Male","issn_l":"1368-5538","issn":["1368-5538","1473-0790"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Male","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1982170652.pdf","grobid_xml":"https://content.openalex.org/works/W1982170652.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1575389635","https://openalex.org/W1589045113","https://openalex.org/W1929501887","https://openalex.org/W2002510710","https://openalex.org/W2009810419","https://openalex.org/W2010470045","https://openalex.org/W2013808208","https://openalex.org/W2023677383","https://openalex.org/W2030450391","https://openalex.org/W2041481588","https://openalex.org/W2051349787","https://openalex.org/W2065888972","https://openalex.org/W2085732473","https://openalex.org/W2087684585","https://openalex.org/W2091017387","https://openalex.org/W2092048322","https://openalex.org/W2096237552","https://openalex.org/W2096714067","https://openalex.org/W2097830439","https://openalex.org/W2099202505","https://openalex.org/W2102179430","https://openalex.org/W2102246394","https://openalex.org/W2102900240","https://openalex.org/W2106039105","https://openalex.org/W2111728603","https://openalex.org/W2113311257","https://openalex.org/W2113645951","https://openalex.org/W2116536714","https://openalex.org/W2130714023","https://openalex.org/W2134451964","https://openalex.org/W2138332837","https://openalex.org/W2142908894","https://openalex.org/W2160234571","https://openalex.org/W2164059021","https://openalex.org/W2400866603","https://openalex.org/W2616432380"],"related_works":["https://openalex.org/W7057789541","https://openalex.org/W3022323630","https://openalex.org/W3115465862","https://openalex.org/W2910898725","https://openalex.org/W1985592735","https://openalex.org/W4394734558","https://openalex.org/W3164430538","https://openalex.org/W7096535992","https://openalex.org/W1575389635","https://openalex.org/W2133236743"],"abstract_inverted_index":{"An":[0],"open-label":[1],"follow-up":[2],"study":[3,196],"of":[4,80],"low-to-intermediate":[5,199],"dose":[6,200],"testosterone":[7,39],"replacement":[8],"therapy":[9],"(TRT)":[10],"was":[11,85,133],"conducted":[12],"in":[13,138,149,164,174,206,216,224],"64":[14],"overweight":[15,226],"patients":[16,208],"(aged":[17],"65-75":[18],"years)":[19],"with":[20,108,181,186,192,218,228],"late":[21],"onset":[22],"hypogonadism":[23],"(LOH)":[24],"and":[25,57,61,70,75,105,121,131,158,171,188,212,221,230],"increased":[26,137],"fasting":[27,232],"plasma":[28],"glucose":[29],"(FPG).":[30],"Patients":[31],"were":[32,73,119],"subdivided":[33],"into":[34],"four":[35],"treatment":[36,55,140],"groups:":[37],"oral":[38,143,193],"(T)":[40],"(T":[41],"undecanoate,":[42],"80":[43],"mg/d),":[44,48],"transmucosal":[45,187],"T":[46,50,72,135,144,190],"(60":[47],"transdermal":[49,189],"(30":[51],"mg/d)":[52],"or":[53],"no":[54],"(control),":[56],"evaluated":[58,120],"at":[59],"0":[60],"6":[62,179],"months.":[63],"FPG,":[64],"hemoglobin":[65],"(Hb),":[66],"prostate-specific":[67],"antigen":[68],"(PSA)":[69],"total":[71],"measured":[74],"the":[76,142,150],"Homeostasis":[77],"Model":[78],"Assessment":[79],"Insulin":[81],"Resistance":[82],"(HOMA-IR)":[83],"index":[84,89],"calculated.":[86,134],"Body":[87],"mass":[88],"(BMI),":[90],"waist":[91,168],"circumference,":[92,169],"fitness":[93],"level":[94],"(6-min":[95],"walking":[96],"test),":[97],"Aging":[98],"Males'":[99],"Symptoms":[100],"(AMS)":[101],"scale,":[102],"handgrip":[103],"strength":[104],"energy":[106],"expenditure":[107],"physical":[109],"activity":[110],"(Minnesota":[111],"questionnaire":[112],"for":[113],"Leisure":[114],"Time":[115],"Physical":[116],"Activity":[117],"(LTPA))":[118],"a":[122,182],"\"frailty":[123],"score\"":[124],"(based":[125],"on:":[126],"grip":[127],"strength,":[128],"gait":[129],"speed":[130],"LTPA)":[132],"levels":[136],"all":[139,175],"groups;":[141],"group":[145],"had":[146],"values":[147],"still":[148],"hypogonadal":[151],"range":[152],"(5.9":[153],"\u00b1":[154],"1.1":[155],"nmol/L).":[156],"PSA":[157],"Hb":[159],"concentrations":[160],"did":[161],"not":[162],"change":[163],"any":[165],"group.":[166],"BMI,":[167],"FPG":[170],"HOMA-IR":[172],"improved":[173,219],"T-treated":[176],"groups":[177],"after":[178],"months,":[180],"greater":[183],"effect":[184],"seen":[185],"compared":[191],"T.":[194],"This":[195],"indicates":[197],"that":[198],"TRT":[201],"may":[202],"be":[203],"safely":[204],"utilized":[205],"LOH":[207,229],"to":[209],"ameliorate":[210],"somatic":[211],"psychological":[213],"frailty":[214],"symptoms":[215],"association":[217],"anthropometric":[220],"glycometabolic":[222],"parameters":[223],"aging,":[225],"men":[227],"impaired":[231],"glucose.":[233]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}