{"id":"https://openalex.org/W1982165240","doi":"https://doi.org/10.1118/1.4815751","title":"TH\u2010C\u2010137\u201008: Dosimetric Quality of An Automatic IMRT Planning Method for Head and Neck Cancer Cases","display_name":"TH\u2010C\u2010137\u201008: Dosimetric Quality of An Automatic IMRT Planning Method for Head and Neck Cancer Cases","publication_year":2013,"publication_date":"2013-06-01","ids":{"openalex":"https://openalex.org/W1982165240","doi":"https://doi.org/10.1118/1.4815751","mag":"1982165240"},"language":"en","primary_location":{"id":"doi:10.1118/1.4815751","doi":"https://doi.org/10.1118/1.4815751","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.4815751","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012912433","display_name":"Lingshu Yuan","orcid":"https://orcid.org/0000-0002-5085-419X","observed_orcids":["https://orcid.org/0000-0002-5085-419X"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L Yuan","raw_affiliation_strings":["Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090955945","display_name":"Tingtian Pang","orcid":"https://orcid.org/0000-0002-0640-4204","observed_orcids":["https://orcid.org/0000-0002-0640-4204"]},"institutions":[{"id":"https://openalex.org/I2801228662","display_name":"Peking Union Medical College Hospital","ror":"https://ror.org/04jztag35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801228662"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"T Pang","raw_affiliation_strings":["Peking Union Medical College Hospital, Beijing, Beijing"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peking Union Medical College Hospital, Beijing, Beijing","institution_ids":["https://openalex.org/I2801228662"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Y Ge","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102149020","display_name":"University of North Carolina at Charlotte","ror":"https://ror.org/04dawnj30","country_code":"US","type":"education","lineage":["https://openalex.org/I102149020"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Y Ge","raw_affiliation_strings":["University of North Carolina at Charlotte, Charlotte, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of North Carolina at Charlotte, Charlotte, North Carolina","institution_ids":["https://openalex.org/I102149020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070880484","display_name":"T Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T Li","raw_affiliation_strings":["Duke University Medical Ctr., Durham, NC","Duke Univ Medical Ctr, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Medical Ctr., Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Duke Univ Medical Ctr, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100651695","display_name":"F.-F. Yin","orcid":"https://orcid.org/0000-0002-2025-4740","observed_orcids":["https://orcid.org/0000-0002-2025-4740"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F Yin","raw_affiliation_strings":["Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069570157","display_name":"Qiuwen Wu","orcid":"https://orcid.org/0000-0003-0748-7280","observed_orcids":["https://orcid.org/0000-0003-0748-7280"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Q Jackie Wu","raw_affiliation_strings":["Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.09498267,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"40","issue":"6Part32","first_page":"534","last_page":"534"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/head-and-neck-cancer","display_name":"head and neck cancer","score":0.9869999885559082},{"id":"https://openalex.org/keywords/organs-at-risk-sparing","display_name":"organs at risk sparing","score":0.7590000033378601},{"id":"https://openalex.org/keywords/dose-uniformity","display_name":"dose homogeneity","score":0.5529999732971191},{"id":"https://openalex.org/keywords/brainstem-sparing","display_name":"brainstem sparing","score":0.5479999780654907}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6976374983787537},{"id":"https://openalex.org/C2776530083","wikidata":"https://www.wikidata.org/wiki/Q1783924","display_name":"Head and neck cancer","level":3,"score":0.6201950907707214},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.6169432401657104},{"id":"https://openalex.org/C2780474809","wikidata":"https://www.wikidata.org/wiki/Q9637","display_name":"Larynx","level":2,"score":0.6017469167709351},{"id":"https://openalex.org/C75088862","wikidata":"https://www.wikidata.org/wiki/Q2291081","display_name":"Dosimetry","level":2,"score":0.5666972994804382},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.529308557510376},{"id":"https://openalex.org/C106436119","wikidata":"https://www.wikidata.org/wiki/Q836575","display_name":"Quality assurance","level":3,"score":0.5130549669265747},{"id":"https://openalex.org/C3018411727","wikidata":"https://www.wikidata.org/wiki/Q3867488","display_name":"Head and neck","level":2,"score":0.4999525547027588},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.44918689131736755},{"id":"https://openalex.org/C2776752453","wikidata":"https://www.wikidata.org/wiki/Q174778","display_name":"Pharynx","level":2,"score":0.43320319056510925},{"id":"https://openalex.org/C2986629439","wikidata":"https://www.wikidata.org/wiki/Q9635","display_name":"Oral cavity","level":2,"score":0.4224967360496521},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.33568552136421204},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2704828679561615},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.1039104163646698},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.09763097763061523},{"id":"https://openalex.org/C2778618615","wikidata":"https://www.wikidata.org/wiki/Q4008393","display_name":"External quality assessment","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1118/1.4815751","doi":"https://doi.org/10.1118/1.4815751","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.4815751","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2003039575","https://openalex.org/W2473940509","https://openalex.org/W2046377885","https://openalex.org/W2956105971","https://openalex.org/W2315332959","https://openalex.org/W2537945227","https://openalex.org/W2024466247","https://openalex.org/W1998719655","https://openalex.org/W2561224290","https://openalex.org/W3167138517"],"abstract_inverted_index":{"Purpose:":[0],"To":[1],"evaluate":[2],"the":[3,47,54,86,108,113,123,139,150,156,158,165,168,172,176,218,227,230,239,260,265,271,283],"dosimetric":[4,105,169,231,291],"quality":[5,292],"of":[6,93,107,164,167,229],"an":[7],"automatic":[8,278],"IMRT":[9,30,64,279,296],"planning":[10,280],"method":[11,281],"for":[12,37,97,237],"Head":[13],"and":[14,41,71,79,110,305],"Neck":[15],"(HN)":[16],"cancer":[17,22],"cases.":[18],"Methods:":[19],"Eighteen":[20],"HN":[21],"patients":[23],"are":[24,43,60,69,83,118,179,233],"planned":[25],"with":[26,147,175,290],"nine":[27],"equally":[28],"spaced":[29],"beams.":[31],"The":[32,57,66,104,132,213,277],"OAR":[33,48],"dose":[34,135,253,263,273],"sparing":[35,274],"objectives":[36],"each":[38,98],"plan":[39,87],"(primary":[40],"boost)":[42],"generated":[44,115,298],"automatically":[45,114],"by":[46,62,85,126,299,303],"DVH":[49,58,284],"prediction":[50,285],"models":[51,59,286],"based":[52,76],"on":[53],"patient":[55],"anatomy.":[56],"trained":[61],"prior":[63],"plans.":[65],"predicted":[67],"DVHs":[68],"sampled":[70],"transformed":[72],"into":[73],"a":[74,127,306],"template":[75],"dosevolume":[77],"constraints":[78],"optimization":[80,88,94],"priorities":[81],"which":[82,144,246],"utilized":[84],"algorithm.":[89],"Only":[90],"one":[91],"round":[92],"was":[95],"performed":[96],"case":[99],"without":[100],"any":[101],"human":[102],"intervention.":[103],"parameters":[106,170,232],"OARs":[109,219,241],"PTV":[111,134],"in":[112,138,149,162,171,224,255,264],"plans":[116,125,152,178,268,289,297],"(auto\u2010plans)":[117],"evaluated":[119],"against":[120],"those":[121],"from":[122],"clinical":[124,151,177,267,295],"paired":[128],"comparison":[129],"method.":[130],"Results:":[131],"average":[133],"homogeneity":[136],"(D2%\u2013D99%)":[137],"auto\u2010plans":[140,173,257],"is":[141,145,247],"5.5":[142],"Gy,":[143],"comparable":[146,293],"that":[148],"(5.4":[153],"Gy).":[154],"For":[155],"OARs,":[157],"means":[159],"(standard":[160],"deviation":[161],"parenthesis)":[163],"differences":[166,228],"compared":[174],"(in":[180],"Gy):":[181],"parotids":[182],"D50%:":[183,188,192],"\u22122.5":[184],"(9.4),":[185],"oral":[186],"cavity":[187],"\u22120.9":[189,207],"(3.5),":[190],"larynx":[191],"\u22121.3":[193],"(9.7),":[194],"pharynx":[195],"D2%:":[196,201,206,210],"\u22120.3":[197],"(3.6),":[198],"spinal":[199,243,251,261],"cord":[200,244,252,262],"\u2212":[202],"2.2":[203],"(4.0),":[204],"brainstem":[205],"(3.9),":[208],"mandible":[209],"\u22120.4":[211],"(1.3).":[212],"negative":[214],"mean":[215],"values":[216],"indicate":[217],"can":[220,287],"be":[221],"further":[222],"spared":[223],"average.":[225],"However,":[226],"not":[234],"statistically":[235],"significant":[236],"all":[238],"other":[240],"except":[242],"(p=0.002),":[245],"due":[248],"to":[249,294],"large":[250],"reduction":[254],"several":[256],"even":[258],"when":[259],"corresponding":[266],"have":[269],"met":[270],"physician's":[272],"constraint.":[275],"Conclusion:":[276],"utilizing":[282],"generate":[288],"experts.":[300],"Partly":[301],"supported":[302],"NIH/NCI":[304],"Varian":[307],"master":[308],"research":[309],"grant.":[310]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}