{"id":"https://openalex.org/W1982076751","doi":"https://doi.org/10.1016/0014-4827(86)90031-5","title":"Thyrotropin-induced formation of functional follicles in primary cultures of ovine thyroid cells","display_name":"Thyrotropin-induced formation of functional follicles in primary cultures of ovine thyroid cells","publication_year":1986,"publication_date":"1986-06-01","ids":{"openalex":"https://openalex.org/W1982076751","doi":"https://doi.org/10.1016/0014-4827(86)90031-5","mag":"1982076751","pmid":"https://pubmed.ncbi.nlm.nih.gov/3519250"},"language":"en","primary_location":{"id":"doi:10.1016/0014-4827(86)90031-5","doi":"https://doi.org/10.1016/0014-4827(86)90031-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0014-4827(86)90031-5","pdf_url":null,"source":{"id":"https://openalex.org/S132505712","display_name":"Experimental Cell Research","issn_l":"0014-4827","issn":["0014-4827","1090-2422"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Cell Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108772643","display_name":"Wendy Mak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"W.W. Mak","raw_affiliation_strings":["Banting and Best Departments of Medical Research and Department of Medicine, University of Toronto, Toronto, Ontario, Canada M5G 1L6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banting and Best Departments of Medical Research and Department of Medicine, University of Toronto, Toronto, Ontario, Canada M5G 1L6","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083181041","display_name":"Janice E. Errick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"J.E. Errick","raw_affiliation_strings":["Banting and Best Departments of Medical Research and Department of Medicine, University of Toronto, Toronto, Ontario, Canada M5G 1L6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banting and Best Departments of Medical Research and Department of Medicine, University of Toronto, Toronto, Ontario, Canada M5G 1L6","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103455829","display_name":"Raymond C. Chan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"R.C. Chan","raw_affiliation_strings":["Prince of Wales Hospital, Tai Po, N.T., Hong Kong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Prince of Wales Hospital, Tai Po, N.T., Hong Kong","institution_ids":["https://openalex.org/I4210114914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110145609","display_name":"Margaret C. Eggo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M.C. Eggo","raw_affiliation_strings":["Banting and Best Departments of Medical Research and Department of Medicine, University of Toronto, Toronto, Ontario, Canada M5G 1L6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banting and Best Departments of Medical Research and Department of Medicine, University of Toronto, Toronto, Ontario, Canada M5G 1L6","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109130665","display_name":"G N Burrow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"G.N. Burrow","raw_affiliation_strings":["Banting and Best Departments of Medical Research and Department of Medicine, University of Toronto, Toronto, Ontario, Canada M5G 1L6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banting and Best Departments of Medical Research and Department of Medicine, University of Toronto, Toronto, Ontario, Canada M5G 1L6","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5108772643"],"corresponding_institution_ids":["https://openalex.org/I185261750"],"apc_list":{"value":3270,"currency":"USD","value_usd":3270},"apc_paid":null,"fwci":1.1925,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.76102346,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"164","issue":"2","first_page":"311","last_page":"322"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13563","display_name":"Chemical Analysis and Environmental Impact","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thyroid-stimulating-hormone","display_name":"thyroid-stimulating hormone","score":0.9670000076293945},{"id":"https://openalex.org/keywords/follicle-formation","display_name":"follicle formation","score":0.781000018119812},{"id":"https://openalex.org/keywords/primary-culture","display_name":"primary cell culture","score":0.6869999766349792},{"id":"https://openalex.org/keywords/thyroglobulin","display_name":"thyroglobulin","score":0.7200000286102295},{"id":"https://openalex.org/keywords/iodination","display_name":"iodination","score":0.8270000219345093},{"id":"https://openalex.org/keywords/microvilli","display_name":"microvilli","score":0.9459999799728394},{"id":"https://openalex.org/keywords/follicle-differentiation","display_name":"follicle differentiation","score":0.49799999594688416},{"id":"https://openalex.org/keywords/thyroid-cell-differentiation","display_name":"thyroid cell differentiation","score":0.3540000021457672}],"concepts":[{"id":"https://openalex.org/C2778835679","wikidata":"https://www.wikidata.org/wiki/Q412228","display_name":"Thyroglobulin","level":3,"score":0.8289918303489685},{"id":"https://openalex.org/C187785154","wikidata":"https://www.wikidata.org/wiki/Q5464664","display_name":"Follicular phase","level":2,"score":0.7953285574913025},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7158398628234863},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.6708837747573853},{"id":"https://openalex.org/C2778057883","wikidata":"https://www.wikidata.org/wiki/Q92793969","display_name":"Follicular cell","level":3,"score":0.6191791892051697},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.546306312084198},{"id":"https://openalex.org/C131631996","wikidata":"https://www.wikidata.org/wiki/Q1141325","display_name":"Lumen (anatomy)","level":2,"score":0.5396192073822021},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5233290195465088},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4572245180606842},{"id":"https://openalex.org/C102570824","wikidata":"https://www.wikidata.org/wiki/Q147807","display_name":"Follicle","level":2,"score":0.41956087946891785},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.38562726974487305},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21329841017723083},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008871","descriptor_name":"Microvilli","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D013972","descriptor_name":"Thyrotropin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0014-4827(86)90031-5","doi":"https://doi.org/10.1016/0014-4827(86)90031-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0014-4827(86)90031-5","pdf_url":null,"source":{"id":"https://openalex.org/S132505712","display_name":"Experimental Cell Research","issn_l":"0014-4827","issn":["0014-4827","1090-2422"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Cell Research","raw_type":"journal-article"},{"id":"pmid:3519250","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3519250","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental cell research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W433469126","https://openalex.org/W587953782","https://openalex.org/W1971974435","https://openalex.org/W1974943346","https://openalex.org/W1985127862","https://openalex.org/W1989636209","https://openalex.org/W1999778948","https://openalex.org/W2000486441","https://openalex.org/W2007173674","https://openalex.org/W2014075185","https://openalex.org/W2030316357","https://openalex.org/W2033033456","https://openalex.org/W2041825087","https://openalex.org/W2042743000","https://openalex.org/W2043613969","https://openalex.org/W2045304550","https://openalex.org/W2049584097","https://openalex.org/W2051749020","https://openalex.org/W2063753069","https://openalex.org/W2064757733","https://openalex.org/W2081660403","https://openalex.org/W2082438371","https://openalex.org/W2090780998","https://openalex.org/W2096268773","https://openalex.org/W2146311475","https://openalex.org/W2157925396","https://openalex.org/W2163388759","https://openalex.org/W2345436087","https://openalex.org/W2948847911"],"related_works":["https://openalex.org/W2014075185","https://openalex.org/W1974694255","https://openalex.org/W7096459184","https://openalex.org/W91500897","https://openalex.org/W1974943346","https://openalex.org/W2414276764","https://openalex.org/W2016895650","https://openalex.org/W2035378919","https://openalex.org/W2072105881","https://openalex.org/W1968201424"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}