{"id":"https://openalex.org/W1981017596","doi":"https://doi.org/10.1586/erc.10.91","title":"Understanding the molecular basis for cardiomyocyte cell cycle regulation: new insights in cardiac regeneration after injury?","display_name":"Understanding the molecular basis for cardiomyocyte cell cycle regulation: new insights in cardiac regeneration after injury?","publication_year":2010,"publication_date":"2010-07-30","ids":{"openalex":"https://openalex.org/W1981017596","doi":"https://doi.org/10.1586/erc.10.91","mag":"1981017596","pmid":"https://pubmed.ncbi.nlm.nih.gov/20670179"},"language":"en","primary_location":{"id":"doi:10.1586/erc.10.91","doi":"https://doi.org/10.1586/erc.10.91","is_oa":true,"landing_page_url":"https://doi.org/10.1586/erc.10.91","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1586/erc.10.91?needAccess=true","source":{"id":"https://openalex.org/S108504264","display_name":"Expert Review of Cardiovascular Therapy","issn_l":"1477-9072","issn":["1477-9072","1744-8344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Cardiovascular Therapy","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.1586/erc.10.91?needAccess=true","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026937459","display_name":"N\u00faria Montserrat","orcid":"https://orcid.org/0000-0002-1603-1755","observed_orcids":["https://orcid.org/0000-0002-1603-1755"]},"institutions":[{"id":"https://openalex.org/I4210138155","display_name":"Center of Regenerative Medicine in Barcelona","ror":"https://ror.org/03q0p7c86","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210138155","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Nuria Montserrat","raw_affiliation_strings":["Center for Regenerative Medicine in Barcelona, Dr. Aiguader, 88, 08003, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Regenerative Medicine in Barcelona, Dr. Aiguader, 88, 08003, Barcelona, Spain","institution_ids":["https://openalex.org/I4210138155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072205273","display_name":"Chris Jopling","orcid":"https://orcid.org/0000-0003-0950-0063","observed_orcids":["https://orcid.org/0000-0003-0950-0063"]},"institutions":[{"id":"https://openalex.org/I4210138155","display_name":"Center of Regenerative Medicine in Barcelona","ror":"https://ror.org/03q0p7c86","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210138155","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Chris Jopling","raw_affiliation_strings":["Center for Regenerative Medicine in Barcelona, Dr. Aiguader, 88, 08003, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Regenerative Medicine in Barcelona, Dr. Aiguader, 88, 08003, Barcelona, Spain","institution_ids":["https://openalex.org/I4210138155"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050690657","display_name":"Juan Carlos Izpis\u00faa Belmonte","orcid":"https://orcid.org/0000-0003-0557-8875","observed_orcids":["https://orcid.org/0000-0003-0557-8875"]},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]},{"id":"https://openalex.org/I4210138155","display_name":"Center of Regenerative Medicine in Barcelona","ror":"https://ror.org/03q0p7c86","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210138155","https://openalex.org/I4387153040"]}],"countries":["ES","US"],"is_corresponding":false,"raw_author_name":"Juan Carlos Izpis\u00faa Belmonte","raw_affiliation_strings":["Center for Regenerative Medicine in Barcelona, Dr. Aiguader, 88, 08003, Barcelona, Spain and Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 93027, USA. belmonte@salk.edu; izpisua@cmrb.eu","Salk Institute for Biological Studies, La Jolla, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Regenerative Medicine in Barcelona, Dr. Aiguader, 88, 08003, Barcelona, Spain and Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 93027, USA. belmonte@salk.edu; izpisua@cmrb.eu","institution_ids":["https://openalex.org/I1307098950","https://openalex.org/I4210138155"]},{"raw_affiliation_string":"Salk Institute for Biological Studies, La Jolla, United States","institution_ids":["https://openalex.org/I1307098950"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"8","issue":"8","first_page":"1043","last_page":"1045"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11677","display_name":"Congenital heart defects research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11677","display_name":"Congenital heart defects research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiac-regeneration","display_name":"cardiac regeneration","score":0.984000027179718},{"id":"https://openalex.org/keywords/cardiac-injury","display_name":"cardiac injury","score":0.7609999775886536},{"id":"https://openalex.org/keywords/cardiac-stem-cells","display_name":"cardiac stem cells","score":0.6869999766349792},{"id":"https://openalex.org/keywords/progenitor-cells","display_name":"progenitor cells","score":0.9110000133514404},{"id":"https://openalex.org/keywords/cardiomyocyte-differentiation","display_name":"cardiomyocyte differentiation","score":0.9459999799728394},{"id":"https://openalex.org/keywords/zebrafish-heart-regeneration","display_name":"zebrafish heart regeneration","score":0.8130000233650208},{"id":"https://openalex.org/keywords/molecular-mechanisms","display_name":"molecular mechanisms","score":0.7099999785423279}],"concepts":[{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.8526041507720947},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.8382978439331055},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7463535070419312},{"id":"https://openalex.org/C3019726847","wikidata":"https://www.wikidata.org/wiki/Q7377","display_name":"Mammalian heart","level":2,"score":0.7168639898300171},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.5624541640281677},{"id":"https://openalex.org/C10854531","wikidata":"https://www.wikidata.org/wiki/Q1061415","display_name":"Regenerative medicine","level":3,"score":0.5338085293769836},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.5174039602279663},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.4535660445690155},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.437372624874115},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3999128043651581},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3718821406364441},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33777928352355957},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.32585442066192627},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2845156192779541},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21146243810653687},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20730015635490417}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012038","descriptor_name":"Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1586/erc.10.91","doi":"https://doi.org/10.1586/erc.10.91","is_oa":true,"landing_page_url":"https://doi.org/10.1586/erc.10.91","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1586/erc.10.91?needAccess=true","source":{"id":"https://openalex.org/S108504264","display_name":"Expert Review of Cardiovascular Therapy","issn_l":"1477-9072","issn":["1477-9072","1744-8344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Cardiovascular Therapy","raw_type":"journal-article"},{"id":"pmid:20670179","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20670179","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert review of cardiovascular therapy","raw_type":"Editorial"}],"best_oa_location":{"id":"doi:10.1586/erc.10.91","doi":"https://doi.org/10.1586/erc.10.91","is_oa":true,"landing_page_url":"https://doi.org/10.1586/erc.10.91","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1586/erc.10.91?needAccess=true","source":{"id":"https://openalex.org/S108504264","display_name":"Expert Review of Cardiovascular Therapy","issn_l":"1477-9072","issn":["1477-9072","1744-8344"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Cardiovascular Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1981017596.pdf","grobid_xml":"https://content.openalex.org/works/W1981017596.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1966202908","https://openalex.org/W1966563415","https://openalex.org/W1998457769","https://openalex.org/W2017100119","https://openalex.org/W2028036560","https://openalex.org/W2052630675","https://openalex.org/W2065171831","https://openalex.org/W2067009965","https://openalex.org/W2078443370","https://openalex.org/W2095059099","https://openalex.org/W2110168421","https://openalex.org/W2126747203","https://openalex.org/W2135975819","https://openalex.org/W2149161770","https://openalex.org/W2163525929","https://openalex.org/W2405998737"],"related_works":["https://openalex.org/W2975750775","https://openalex.org/W3143375899","https://openalex.org/W3007365203","https://openalex.org/W1998457769","https://openalex.org/W2104082179","https://openalex.org/W3110953504","https://openalex.org/W2088772927","https://openalex.org/W3127724593","https://openalex.org/W2099477301","https://openalex.org/W2466154520"],"abstract_inverted_index":{"Extensive":[0],"research":[1],"has":[2],"focused":[3],"on":[4],"the":[5],"identification":[6],"of":[7],"stem":[8],"and":[9,19],"progenitor":[10],"cells":[11],"able":[12],"to":[13],"differentiate":[14],"into":[15],"cardiomyocytes":[16],"after":[17],"injury,":[18],"recent":[20],"findings":[21],"in":[22],"zebrafish":[23],"offer":[24],"hope":[25],"that":[26],"heart":[27],"rege...":[28]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}