{"id":"https://openalex.org/W1980974151","doi":"https://doi.org/10.1016/j.coviro.2014.09.011","title":"Regulation of Flavivirus RNA synthesis and replication","display_name":"Regulation of Flavivirus RNA synthesis and replication","publication_year":2014,"publication_date":"2014-10-17","ids":{"openalex":"https://openalex.org/W1980974151","doi":"https://doi.org/10.1016/j.coviro.2014.09.011","mag":"1980974151","pmid":"https://pubmed.ncbi.nlm.nih.gov/25462437","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4295515"},"language":"en","primary_location":{"id":"doi:10.1016/j.coviro.2014.09.011","doi":"https://doi.org/10.1016/j.coviro.2014.09.011","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.coviro.2014.09.011","pdf_url":null,"source":{"id":"https://openalex.org/S2489902859","display_name":"Current Opinion in Virology","issn_l":"1879-6257","issn":["1879-6257","1879-6265"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Virology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4295515","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071436463","display_name":"Barbara Selisko","orcid":"https://orcid.org/0000-0001-7135-4357","observed_orcids":["https://orcid.org/0000-0001-7135-4357"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210146787","display_name":"Architecture et Fonction des Macromol\u00e9cules Biologiques","ror":"https://ror.org/04jm8zw14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I21491767","https://openalex.org/I4210088668","https://openalex.org/I4210096427","https://openalex.org/I4210146787"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Barbara Selisko","raw_affiliation_strings":["Aix-Marseille Universit\u00e9, AFMB UMR 7257, 13288 Marseille, France; CNRS, AFMB UMR 7257, 13288 Marseille, France","Aix-Marseille Universit\u00e9, AFMB UMR 7257, 13288 Marseille, France","CNRS, AFMB UMR 7257, 13288 Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix-Marseille Universit\u00e9, AFMB UMR 7257, 13288 Marseille, France; CNRS, AFMB UMR 7257, 13288 Marseille, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I21491767","https://openalex.org/I4210146787"]},{"raw_affiliation_string":"Aix-Marseille Universit\u00e9, AFMB UMR 7257, 13288 Marseille, France","institution_ids":["https://openalex.org/I21491767","https://openalex.org/I4210146787"]},{"raw_affiliation_string":"CNRS, AFMB UMR 7257, 13288 Marseille, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210146787"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100661179","display_name":"Chunling Wang","orcid":"https://orcid.org/0000-0002-4187-6098","observed_orcids":["https://orcid.org/0000-0002-4187-6098"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chunling Wang","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, 185 Li Ka Shing Center, Berkeley, CA 94720-3370, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, 185 Li Ka Shing Center, Berkeley, CA 94720-3370, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027442064","display_name":"Eva Harris","orcid":"https://orcid.org/0000-0002-7238-4037","observed_orcids":["https://orcid.org/0000-0002-7238-4037"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eva Harris","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, 185 Li Ka Shing Center, Berkeley, CA 94720-3370, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, 185 Li Ka Shing Center, Berkeley, CA 94720-3370, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039783946","display_name":"Bruno Canard","orcid":"https://orcid.org/0000-0003-4924-1991","observed_orcids":["https://orcid.org/0000-0003-4924-1991"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210146787","display_name":"Architecture et Fonction des Macromol\u00e9cules Biologiques","ror":"https://ror.org/04jm8zw14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I21491767","https://openalex.org/I4210088668","https://openalex.org/I4210096427","https://openalex.org/I4210146787"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Bruno Canard","raw_affiliation_strings":["Aix-Marseille Universit\u00e9, AFMB UMR 7257, 13288 Marseille, France; CNRS, AFMB UMR 7257, 13288 Marseille, France. Electronic address: Bruno.Canard@afmb.univ-mrs.fr","Aix-Marseille Universit\u00e9, AFMB UMR 7257, 13288 Marseille, France","CNRS, AFMB UMR 7257, 13288 Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix-Marseille Universit\u00e9, AFMB UMR 7257, 13288 Marseille, France; CNRS, AFMB UMR 7257, 13288 Marseille, France. Electronic address: Bruno.Canard@afmb.univ-mrs.fr","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I21491767","https://openalex.org/I4210146787"]},{"raw_affiliation_string":"Aix-Marseille Universit\u00e9, AFMB UMR 7257, 13288 Marseille, France","institution_ids":["https://openalex.org/I21491767","https://openalex.org/I4210146787"]},{"raw_affiliation_string":"CNRS, AFMB UMR 7257, 13288 Marseille, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210146787"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5039783946"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I21491767","https://openalex.org/I4210146787"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":null,"fwci":1.149,"has_fulltext":false,"cited_by_count":85,"citation_normalized_percentile":{"value":0.71272869,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"9","issue":null,"first_page":"74","last_page":"83"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flavivirus","display_name":"flavivirus","score":0.9769999980926514},{"id":"https://openalex.org/keywords/rna-dependent-rna-polymerase","display_name":"RNA-dependent RNA polymerase","score":0.8600000143051147},{"id":"https://openalex.org/keywords/viral-rna-synthesis","display_name":"viral RNA synthesis","score":0.8360000252723694},{"id":"https://openalex.org/keywords/rna-replication","display_name":"RNA replication","score":0.8479999899864197},{"id":"https://openalex.org/keywords/replication-complex","display_name":"replication complex","score":0.8539999723434448},{"id":"https://openalex.org/keywords/dengue-virus","display_name":"dengue virus","score":0.8299999833106995},{"id":"https://openalex.org/keywords/west-nile-virus","display_name":"West Nile virus","score":1.0},{"id":"https://openalex.org/keywords/japanese-encephalitis-virus","display_name":"Japanese encephalitis virus","score":1.0},{"id":"https://openalex.org/keywords/virus-host-interactions","display_name":"host-virus interaction","score":0.8259999752044678}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8499709367752075},{"id":"https://openalex.org/C2780568436","wikidata":"https://www.wikidata.org/wiki/Q1165479","display_name":"Flavivirus","level":3,"score":0.8450572490692139},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.7280245423316956},{"id":"https://openalex.org/C41258723","wikidata":"https://www.wikidata.org/wiki/Q2919111","display_name":"RNA-dependent RNA polymerase","level":4,"score":0.5671325922012329},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5452528595924377},{"id":"https://openalex.org/C2776449523","wikidata":"https://www.wikidata.org/wiki/Q272631","display_name":"RNA polymerase","level":4,"score":0.5184183120727539},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.46726173162460327},{"id":"https://openalex.org/C533803919","wikidata":"https://www.wikidata.org/wiki/Q30953","display_name":"Dengue fever","level":2,"score":0.4587794244289398},{"id":"https://openalex.org/C2779635636","wikidata":"https://www.wikidata.org/wiki/Q476209","display_name":"Dengue virus","level":3,"score":0.44988328218460083},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4338078796863556},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3566591143608093},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34609007835388184},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.21527552604675293},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21173501014709473}],"mesh":[{"descriptor_ui":"D005416","descriptor_name":"Flavivirus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005416","descriptor_name":"Flavivirus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012367","descriptor_name":"RNA, Viral","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015967","descriptor_name":"Gene Expression Regulation, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.coviro.2014.09.011","doi":"https://doi.org/10.1016/j.coviro.2014.09.011","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.coviro.2014.09.011","pdf_url":null,"source":{"id":"https://openalex.org/S2489902859","display_name":"Current Opinion in Virology","issn_l":"1879-6257","issn":["1879-6257","1879-6265"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Virology","raw_type":"journal-article"},{"id":"pmid:25462437","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25462437","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in virology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4295515","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4295515","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Opin Virol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4295515","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4295515","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Opin Virol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G7926545638","display_name":"Fitness and Virulence of Dengue Virus in the Context of Changing Host Immunity","funder_award_id":"R01GM087405","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":101,"referenced_works":["https://openalex.org/W1488121527","https://openalex.org/W1493758591","https://openalex.org/W1517586135","https://openalex.org/W1968774761","https://openalex.org/W1970140557","https://openalex.org/W1972132067","https://openalex.org/W1973729131","https://openalex.org/W1976308168","https://openalex.org/W1980892321","https://openalex.org/W1982697237","https://openalex.org/W1983716549","https://openalex.org/W1988411933","https://openalex.org/W1990137452","https://openalex.org/W1991647854","https://openalex.org/W1993881921","https://openalex.org/W1994737397","https://openalex.org/W1998679949","https://openalex.org/W1999605813","https://openalex.org/W2000824758","https://openalex.org/W2006863478","https://openalex.org/W2007789489","https://openalex.org/W2008070981","https://openalex.org/W2011579843","https://openalex.org/W2013519130","https://openalex.org/W2016710993","https://openalex.org/W2019512434","https://openalex.org/W2020962585","https://openalex.org/W2021982580","https://openalex.org/W2023858529","https://openalex.org/W2024970900","https://openalex.org/W2026411906","https://openalex.org/W2030684239","https://openalex.org/W2034182181","https://openalex.org/W2039422585","https://openalex.org/W2039711442","https://openalex.org/W2040997589","https://openalex.org/W2041023803","https://openalex.org/W2046050884","https://openalex.org/W2047550464","https://openalex.org/W2052214918","https://openalex.org/W2052905121","https://openalex.org/W2053792903","https://openalex.org/W2054056331","https://openalex.org/W2057093156","https://openalex.org/W2059655994","https://openalex.org/W2061408603","https://openalex.org/W2062071183","https://openalex.org/W2065200151","https://openalex.org/W2065843293","https://openalex.org/W2066937610","https://openalex.org/W2071749695","https://openalex.org/W2072603184","https://openalex.org/W2077122919","https://openalex.org/W2077587691","https://openalex.org/W2078030963","https://openalex.org/W2079280284","https://openalex.org/W2082881595","https://openalex.org/W2088389272","https://openalex.org/W2088981821","https://openalex.org/W2092052419","https://openalex.org/W2097212976","https://openalex.org/W2101221024","https://openalex.org/W2101643828","https://openalex.org/W2102025023","https://openalex.org/W2103438957","https://openalex.org/W2108353897","https://openalex.org/W2109274528","https://openalex.org/W2109902554","https://openalex.org/W2110233172","https://openalex.org/W2113500493","https://openalex.org/W2114361850","https://openalex.org/W2116553541","https://openalex.org/W2117119827","https://openalex.org/W2117387018","https://openalex.org/W2118614072","https://openalex.org/W2119289230","https://openalex.org/W2119473061","https://openalex.org/W2119569227","https://openalex.org/W2121780828","https://openalex.org/W2121789542","https://openalex.org/W2126573043","https://openalex.org/W2128535933","https://openalex.org/W2133936786","https://openalex.org/W2134917638","https://openalex.org/W2137614522","https://openalex.org/W2141342171","https://openalex.org/W2143482423","https://openalex.org/W2144721356","https://openalex.org/W2145259841","https://openalex.org/W2147372561","https://openalex.org/W2147882701","https://openalex.org/W2149824411","https://openalex.org/W2153621495","https://openalex.org/W2154666681","https://openalex.org/W2158882546","https://openalex.org/W2161110830","https://openalex.org/W2161406362","https://openalex.org/W2161784698","https://openalex.org/W2169543500","https://openalex.org/W2171586566","https://openalex.org/W2172291230"],"related_works":["https://openalex.org/W2902751959","https://openalex.org/W2952260290","https://openalex.org/W2073256630","https://openalex.org/W3113237023","https://openalex.org/W2779700785","https://openalex.org/W2080725002","https://openalex.org/W2527009591","https://openalex.org/W3163796343","https://openalex.org/W2965607935","https://openalex.org/W6903834410"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}