{"id":"https://openalex.org/W1980765362","doi":"https://doi.org/10.1016/j.tetlet.2014.11.100","title":"Improved synthesis of and nucleophilic addition to 2-formyl-2-cyclohexenone","display_name":"Improved synthesis of and nucleophilic addition to 2-formyl-2-cyclohexenone","publication_year":2014,"publication_date":"2014-12-03","ids":{"openalex":"https://openalex.org/W1980765362","doi":"https://doi.org/10.1016/j.tetlet.2014.11.100","mag":"1980765362","pmid":"https://pubmed.ncbi.nlm.nih.gov/25593375","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4290381"},"language":"en","primary_location":{"id":"doi:10.1016/j.tetlet.2014.11.100","doi":"https://doi.org/10.1016/j.tetlet.2014.11.100","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tetlet.2014.11.100","pdf_url":null,"source":{"id":"https://openalex.org/S133942674","display_name":"Tetrahedron Letters","issn_l":"0040-4039","issn":["0040-4039","1873-3581"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4290381","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008461233","display_name":"Elan M. Adary","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149581226","display_name":"Hawaii Pacific University","ror":"https://ror.org/01963ay88","country_code":"US","type":"education","lineage":["https://openalex.org/I149581226"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elan M. Adary","raw_affiliation_strings":["Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813","institution_ids":["https://openalex.org/I149581226"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chih-wei Chang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149581226","display_name":"Hawaii Pacific University","ror":"https://ror.org/01963ay88","country_code":"US","type":"education","lineage":["https://openalex.org/I149581226"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chih-wei Chang","raw_affiliation_strings":["Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813","institution_ids":["https://openalex.org/I149581226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088627882","display_name":"Damian T. D\u2019 Auria","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149581226","display_name":"Hawaii Pacific University","ror":"https://ror.org/01963ay88","country_code":"US","type":"education","lineage":["https://openalex.org/I149581226"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Damian T. D\u2019 Auria","raw_affiliation_strings":["Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813","institution_ids":["https://openalex.org/I149581226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086616481","display_name":"Phuc M. Nguyen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149581226","display_name":"Hawaii Pacific University","ror":"https://ror.org/01963ay88","country_code":"US","type":"education","lineage":["https://openalex.org/I149581226"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Phuc M. Nguyen","raw_affiliation_strings":["Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813","institution_ids":["https://openalex.org/I149581226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029642954","display_name":"Klaudyna Polewacz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149581226","display_name":"Hawaii Pacific University","ror":"https://ror.org/01963ay88","country_code":"US","type":"education","lineage":["https://openalex.org/I149581226"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Klaudyna Polewacz","raw_affiliation_strings":["Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813","institution_ids":["https://openalex.org/I149581226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023246206","display_name":"Justin Reinicke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149581226","display_name":"Hawaii Pacific University","ror":"https://ror.org/01963ay88","country_code":"US","type":"education","lineage":["https://openalex.org/I149581226"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Justin A. Reinicke","raw_affiliation_strings":["Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813","institution_ids":["https://openalex.org/I149581226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001868272","display_name":"Hannah Seo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149581226","display_name":"Hawaii Pacific University","ror":"https://ror.org/01963ay88","country_code":"US","type":"education","lineage":["https://openalex.org/I149581226"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hannah Seo","raw_affiliation_strings":["Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813","institution_ids":["https://openalex.org/I149581226"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021316503","display_name":"Gideon O. Berger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149581226","display_name":"Hawaii Pacific University","ror":"https://ror.org/01963ay88","country_code":"US","type":"education","lineage":["https://openalex.org/I149581226"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gideon O. Berger","raw_affiliation_strings":["Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Natural Sciences, Hawai'i Pacific University, Honolulu, Hawai'i, 96813","institution_ids":["https://openalex.org/I149581226"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5021316503"],"corresponding_institution_ids":["https://openalex.org/I149581226"],"apc_list":{"value":3610,"currency":"USD","value_usd":3610},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.05293773,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"56","issue":"2","first_page":"386","last_page":"389"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.8359000086784363,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.8359000086784363,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.06520000100135803,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13649","display_name":"Advanced Synthetic Organic Chemistry","score":0.05299999937415123,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enone-synthesis","display_name":"enone synthesis","score":0.515999972820282},{"id":"https://openalex.org/keywords/nucleophilic-addition","display_name":"nucleophilic addition","score":0.921999990940094},{"id":"https://openalex.org/keywords/conjugate-addition","display_name":"conjugate addition","score":0.968999981880188},{"id":"https://openalex.org/keywords/dimethyl-malonate","display_name":"dimethyl malonate","score":0.9380000233650208},{"id":"https://openalex.org/keywords/scalable-synthesis","display_name":"scalable synthesis","score":0.6790000200271606}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.924010694026947},{"id":"https://openalex.org/C197336794","wikidata":"https://www.wikidata.org/wiki/Q5161150","display_name":"Conjugate","level":2,"score":0.8534634113311768},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.8191804885864258},{"id":"https://openalex.org/C2777386583","wikidata":"https://www.wikidata.org/wiki/Q209370","display_name":"Cyclohexenone","level":2,"score":0.7650834321975708},{"id":"https://openalex.org/C178907741","wikidata":"https://www.wikidata.org/wiki/Q745930","display_name":"Nucleophile","level":3,"score":0.7634246349334717},{"id":"https://openalex.org/C2777903533","wikidata":"https://www.wikidata.org/wiki/Q2292678","display_name":"Cyclopentenone","level":2,"score":0.6720475554466248},{"id":"https://openalex.org/C2780378348","wikidata":"https://www.wikidata.org/wiki/Q25351438","display_name":"Ring (chemistry)","level":2,"score":0.5280290842056274},{"id":"https://openalex.org/C2779746879","wikidata":"https://www.wikidata.org/wiki/Q3010548","display_name":"Enone","level":2,"score":0.43841439485549927},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.41672319173812866},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.354076623916626},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.35134974122047424},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2926766276359558},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.12020885944366455},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.tetlet.2014.11.100","doi":"https://doi.org/10.1016/j.tetlet.2014.11.100","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tetlet.2014.11.100","pdf_url":null,"source":{"id":"https://openalex.org/S133942674","display_name":"Tetrahedron Letters","issn_l":"0040-4039","issn":["0040-4039","1873-3581"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron Letters","raw_type":"journal-article"},{"id":"pmid:25593375","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25593375","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron letters","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3679604","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4290381","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4290381","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4290381","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Tetrahedron Lett","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3679604","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4290381","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000914798","display_name":"HAWAII INBRE V PROGRAM","funder_award_id":"P20GM103466","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1991700756","https://openalex.org/W2000143175","https://openalex.org/W2011449767","https://openalex.org/W2016687871","https://openalex.org/W2037420573","https://openalex.org/W2061891397","https://openalex.org/W2101284759","https://openalex.org/W2318410142","https://openalex.org/W2952380165"],"related_works":["https://openalex.org/W2952833666","https://openalex.org/W2949062175","https://openalex.org/W2082015735","https://openalex.org/W2019877051","https://openalex.org/W2614788737","https://openalex.org/W2039007658","https://openalex.org/W2135606081","https://openalex.org/W2950828857","https://openalex.org/W2953016507","https://openalex.org/W4247180812"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}