{"id":"https://openalex.org/W1980677355","doi":null,"title":"Hyperbaric oxygen reduced size of chronic leg ulcers: a randomized double-blind study.","display_name":"Hyperbaric oxygen reduced size of chronic leg ulcers: a randomized double-blind study.","publication_year":1994,"publication_date":"1994-04-01","ids":{"openalex":"https://openalex.org/W1980677355","mag":"1980677355","pmid":"https://pubmed.ncbi.nlm.nih.gov/8134442"},"language":"en","primary_location":{"id":"pmid:8134442","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8134442","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and reconstructive surgery","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034613860","display_name":"Christer Hammarlund","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132623","display_name":"Helsingborgs lasarett","ror":"https://ror.org/03am3jt82","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210132623"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"C Hammarlund","raw_affiliation_strings":["Department of Anaesthesia, Helsingborg Hospital, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesia, Helsingborg Hospital, Sweden","institution_ids":["https://openalex.org/I4210132623"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087592421","display_name":"thomas Sundberg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Sundberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":17.322,"has_fulltext":false,"cited_by_count":175,"citation_normalized_percentile":{"value":0.99605434,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"93","issue":"4","first_page":"829","last_page":"33; discussion 834"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9223999977111816,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9223999977111816,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11227","display_name":"Diabetic Foot Ulcer Assessment and Management","score":0.07419999688863754,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11453","display_name":"Diagnosis and Treatment of Venous Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperbaric-oxygen-therapy","display_name":"hyperbaric oxygen therapy","score":1.0},{"id":"https://openalex.org/keywords/chronic-leg-ulcers","display_name":"chronic leg ulcers","score":0.9929999709129333},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.8159999847412109},{"id":"https://openalex.org/keywords/wound-size-reduction","display_name":"wound size reduction","score":0.7450000047683716},{"id":"https://openalex.org/keywords/adjunctive-therapy","display_name":"adjunctive therapy","score":0.5989999771118164}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9777834415435791},{"id":"https://openalex.org/C2994405533","wikidata":"https://www.wikidata.org/wiki/Q731615","display_name":"Hyperbaric oxygen","level":2,"score":0.6372911930084229},{"id":"https://openalex.org/C2781051411","wikidata":"https://www.wikidata.org/wiki/Q2078852","display_name":"Chronic wound","level":3,"score":0.5511531233787537},{"id":"https://openalex.org/C2780630273","wikidata":"https://www.wikidata.org/wiki/Q1988216","display_name":"Oxygen therapy","level":2,"score":0.5509313344955444},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.5413363575935364},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5336284041404724},{"id":"https://openalex.org/C2991744798","wikidata":"https://www.wikidata.org/wiki/Q608510","display_name":"Double blind","level":4,"score":0.4989140033721924},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.48480430245399475},{"id":"https://openalex.org/C12868164","wikidata":"https://www.wikidata.org/wiki/Q1424533","display_name":"Mann\u2013Whitney U test","level":2,"score":0.4217188060283661},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24883604049682617},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.07094541192054749},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006931","descriptor_name":"Hyperbaric Oxygenation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007871","descriptor_name":"Leg Ulcer","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D007871","descriptor_name":"Leg Ulcer","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:8134442","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8134442","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and reconstructive surgery","raw_type":"Clinical Trial"},{"id":"mag:1980677355","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8134442","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2888183906","https://openalex.org/W3194371115","https://openalex.org/W3113677587","https://openalex.org/W2749442960","https://openalex.org/W139400802","https://openalex.org/W2059632066","https://openalex.org/W7023897950","https://openalex.org/W7131395566","https://openalex.org/W2137684067","https://openalex.org/W4317726917"],"abstract_inverted_index":{"To":[0],"evaluate":[1],"the":[2,79,96,106,129,170,173],"effect":[3],"of":[4,54,67,95],"hyperbaric":[5,181],"oxygen":[6,50,107,182],"therapy":[7,183],"on":[8],"chronic":[9,19],"wound":[10,71,80,88,97],"healing,":[11],"16":[12],"otherwise":[13],"healthy":[14],"patients":[15],"who":[16],"had":[17],"nondiabetic,":[18],"leg":[20],"ulcers":[21],"with":[22],"no":[23],"large":[24],"vessel":[25],"disease":[26],"were":[27,34,109],"included":[28],"in":[29,105,128],"a":[30,65,150,160,188],"double-blind":[31],"study.":[32],"Patients":[33],"grouped":[35],"according":[36],"to":[37,43,191],"age":[38],"and":[39,81,103,120,127,142,159],"then":[40,82],"randomly":[41],"assigned":[42],"two":[44],"groups":[45,171],"breathing":[46],"either":[47],"air":[48,130],"or":[49],"at":[51,99,156,166],"2.5":[52],"atmospheres":[53],"absolute":[55],"pressure":[56],"for":[57,64],"90":[58],"minutes":[59],"5":[60],"days":[61],"per":[62],"week":[63,157,167],"total":[66],"30":[68],"treatments.":[69],"The":[70,92],"area":[72],"was":[73],"copied":[74],"onto":[75],"transparent":[76],"film":[77],"covering":[78],"measured":[83],"using":[84,172],"only":[85],"one":[86],"matching":[87],"from":[89],"each":[90],"patient.":[91],"mean":[93],"decrease":[94],"areas":[98],"weeks":[100],"2,":[101],"4,":[102,158],"6":[104,110,168],"group":[108],"percent":[111,116,122,133,138,144],"(SD":[112,117,123,134,139,145],"+/-":[113,118,124,135,140,146],"14),":[114],"22":[115],"13),":[119],"35.7":[121],"17),":[125],"respectively,":[126,148],"group,":[131],"2.8":[132],"11),":[136,141,147],"3.7":[137],"2.7":[143],"giving":[149],"p":[151,161],"value":[152,162],"less":[153,163],"than":[154,164],"0.05":[155],"0.001":[165],"between":[169],"Mann-Whitney":[174],"U":[175],"test.":[176],"These":[177],"data":[178],"indicate":[179],"that":[180],"may":[184],"be":[185],"used":[186],"as":[187],"valuable":[189],"adjunct":[190],"conventional":[192],"therapies":[193],"when":[194],"nondiabetic":[195],"wounds":[196],"do":[197],"not":[198],"heal.":[199]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}