{"id":"https://openalex.org/W1980656139","doi":"https://doi.org/10.1021/jp077556u","title":"Quantifying the Ordering of Adsorbed Proteins In Situ","display_name":"Quantifying the Ordering of Adsorbed Proteins In Situ","publication_year":2008,"publication_date":"2008-01-25","ids":{"openalex":"https://openalex.org/W1980656139","doi":"https://doi.org/10.1021/jp077556u","mag":"1980656139","pmid":"https://pubmed.ncbi.nlm.nih.gov/18217748"},"language":"en","primary_location":{"id":"doi:10.1021/jp077556u","doi":"https://doi.org/10.1021/jp077556u","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jp077556u","pdf_url":null,"source":{"id":"https://openalex.org/S185621672","display_name":"The Journal of Physical Chemistry B","issn_l":"1520-5207","issn":["1520-5207","1520-6106"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Physical Chemistry B","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100440015","display_name":"Jie Wang","orcid":"https://orcid.org/0000-0001-8010-0500","observed_orcids":["https://orcid.org/0000-0001-8010-0500"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jie Wang","raw_affiliation_strings":["Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109","Department of Chemistry; University of Michigan; Ann Arbor Michigan 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Chemistry; University of Michigan; Ann Arbor Michigan 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100381300","display_name":"Sang Ho Lee","orcid":"https://orcid.org/0000-0002-4954-3861","observed_orcids":["https://orcid.org/0000-0002-4954-3861"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sang-Ho Lee","raw_affiliation_strings":["Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054123780","display_name":"Zhan Chen","orcid":"https://orcid.org/0000-0001-8687-8348","observed_orcids":["https://orcid.org/0000-0001-8687-8348"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhan Chen","raw_affiliation_strings":["Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I27837315"],"apc_list":null,"apc_paid":null,"fwci":5.7899,"has_fulltext":false,"cited_by_count":77,"citation_normalized_percentile":{"value":0.97198434,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"112","issue":"7","first_page":"2281","last_page":"2290"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11177","display_name":"Spectroscopy and Quantum Chemical Studies","score":0.5210000276565552,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11177","display_name":"Spectroscopy and Quantum Chemical Studies","score":0.5210000276565552,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.24300000071525574,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.21250000596046448,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-adsorption","display_name":"protein adsorption","score":0.9509999752044678},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":0.7919999957084656},{"id":"https://openalex.org/keywords/polystyrene-surfaces","display_name":"polystyrene surfaces","score":0.8050000071525574},{"id":"https://openalex.org/keywords/protein-orientation","display_name":"protein orientation","score":0.8130000233650208},{"id":"https://openalex.org/keywords/protein-conformation","display_name":"protein conformation","score":0.9860000014305115},{"id":"https://openalex.org/keywords/coiled-coil","display_name":"coiled coil","score":0.6269999742507935},{"id":"https://openalex.org/keywords/sum-frequency-generation-spectroscopy","display_name":"sum frequency generation spectroscopy","score":0.7649999856948853},{"id":"https://openalex.org/keywords/atr-ftir-spectroscopy","display_name":"ATR-FTIR spectroscopy","score":0.8230000138282776},{"id":"https://openalex.org/keywords/error-analysis","display_name":"error analysis","score":0.5099999904632568}],"concepts":[{"id":"https://openalex.org/C160892712","wikidata":"https://www.wikidata.org/wiki/Q901559","display_name":"Fourier transform infrared spectroscopy","level":2,"score":0.7538666725158691},{"id":"https://openalex.org/C49102809","wikidata":"https://www.wikidata.org/wiki/Q300035","display_name":"Attenuated total reflection","level":3,"score":0.7416372895240784},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.645591139793396},{"id":"https://openalex.org/C2777207611","wikidata":"https://www.wikidata.org/wiki/Q1554233","display_name":"Sum frequency generation spectroscopy","level":5,"score":0.6065648794174194},{"id":"https://openalex.org/C32891209","wikidata":"https://www.wikidata.org/wiki/Q483666","display_name":"Spectroscopy","level":2,"score":0.5516480207443237},{"id":"https://openalex.org/C2777922577","wikidata":"https://www.wikidata.org/wiki/Q146243","display_name":"Polystyrene","level":3,"score":0.551364004611969},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.5292750597000122},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.5165785551071167},{"id":"https://openalex.org/C102519508","wikidata":"https://www.wikidata.org/wiki/Q6520159","display_name":"Fourier transform","level":2,"score":0.5118185877799988},{"id":"https://openalex.org/C153642686","wikidata":"https://www.wikidata.org/wiki/Q70906","display_name":"Infrared spectroscopy","level":2,"score":0.4929642677307129},{"id":"https://openalex.org/C41610221","wikidata":"https://www.wikidata.org/wiki/Q2047974","display_name":"Fourier transform spectroscopy","level":3,"score":0.4822574257850647},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.4413442611694336},{"id":"https://openalex.org/C158355884","wikidata":"https://www.wikidata.org/wiki/Q11388","display_name":"Infrared","level":2,"score":0.43827518820762634},{"id":"https://openalex.org/C65682993","wikidata":"https://www.wikidata.org/wiki/Q1056451","display_name":"Reflection (computer programming)","level":2,"score":0.43158113956451416},{"id":"https://openalex.org/C160018778","wikidata":"https://www.wikidata.org/wiki/Q3123190","display_name":"Sum-frequency generation","level":4,"score":0.4249665439128876},{"id":"https://openalex.org/C2777822432","wikidata":"https://www.wikidata.org/wiki/Q216681","display_name":"In situ","level":2,"score":0.41116976737976074},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.2145189344882965},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.15651604533195496},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.15113982558250427},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.13594627380371094},{"id":"https://openalex.org/C78854221","wikidata":"https://www.wikidata.org/wiki/Q756033","display_name":"Nonlinear optics","level":3,"score":0.08536344766616821},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08119869232177734},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000327","descriptor_name":"Adsorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005340","descriptor_name":"Fibrinogen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011137","descriptor_name":"Polystyrenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1021/jp077556u","doi":"https://doi.org/10.1021/jp077556u","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jp077556u","pdf_url":null,"source":{"id":"https://openalex.org/S185621672","display_name":"The Journal of Physical Chemistry B","issn_l":"1520-5207","issn":["1520-5207","1520-6106"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Physical Chemistry B","raw_type":"journal-article"},{"id":"pmid:18217748","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18217748","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of physical chemistry. B","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323155","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W636025489","https://openalex.org/W1976302627","https://openalex.org/W1976325303","https://openalex.org/W1977854765","https://openalex.org/W1979657804","https://openalex.org/W1985676128","https://openalex.org/W1993821685","https://openalex.org/W1994014080","https://openalex.org/W1995331181","https://openalex.org/W2002633270","https://openalex.org/W2003670177","https://openalex.org/W2006127000","https://openalex.org/W2007699797","https://openalex.org/W2008306409","https://openalex.org/W2008419284","https://openalex.org/W2009886725","https://openalex.org/W2011794114","https://openalex.org/W2013107255","https://openalex.org/W2013609412","https://openalex.org/W2017415483","https://openalex.org/W2030219964","https://openalex.org/W2031361175","https://openalex.org/W2036316665","https://openalex.org/W2037855380","https://openalex.org/W2041496163","https://openalex.org/W2045111209","https://openalex.org/W2047501009","https://openalex.org/W2048981720","https://openalex.org/W2054602599","https://openalex.org/W2056154520","https://openalex.org/W2057678070","https://openalex.org/W2057823986","https://openalex.org/W2062135876","https://openalex.org/W2062428706","https://openalex.org/W2065295334","https://openalex.org/W2069366616","https://openalex.org/W2071799231","https://openalex.org/W2076166510","https://openalex.org/W2078589249","https://openalex.org/W2079412851","https://openalex.org/W2079493449","https://openalex.org/W2084981076","https://openalex.org/W2097339478","https://openalex.org/W2098908528","https://openalex.org/W2103722820","https://openalex.org/W2121242766","https://openalex.org/W2123998092","https://openalex.org/W2142699633","https://openalex.org/W2144754539","https://openalex.org/W2160564267","https://openalex.org/W2166114665","https://openalex.org/W2504298576","https://openalex.org/W2952267572"],"related_works":["https://openalex.org/W2015755767","https://openalex.org/W2007699797","https://openalex.org/W4360806517","https://openalex.org/W2051290691","https://openalex.org/W2051600836","https://openalex.org/W2316031058","https://openalex.org/W2761576629","https://openalex.org/W2021080831","https://openalex.org/W2075190292","https://openalex.org/W2307813190"],"abstract_inverted_index":{"We":[0],"have":[1],"investigated":[2],"the":[3,11,55,66],"orientation":[4,60],"and":[5,74,97],"conformation":[6],"of":[7,62,100],"protein":[8],"molecules":[9],"at":[10,65,102],"polystyrene":[12],"(PS)/protein":[13],"solution":[14],"interface":[15,67],"using":[16,107],"sum":[17],"frequency":[18],"generation":[19],"(SFG)":[20],"vibrational":[21],"spectroscopy,":[22],"supplemented":[23,109],"by":[24,71,110],"attenuated":[25],"total":[26],"reflection":[27],"Fourier":[28],"transform":[29],"infrared":[30],"spectroscopy":[31],"(ATR-FTIR).":[32],"In":[33],"this":[34],"research,":[35],"we":[36],"studied":[37,106],"fibrinogen":[38,47,63],"as":[39,95],"a":[40,49,81],"model":[41],"protein.":[42],"SFG":[43,73,108],"studies":[44],"indicate":[45],"that":[46,90],"adopts":[48],"bent":[50],"structure":[51],"after":[52],"adsorbing":[53],"to":[54],"PS":[56],"surface.":[57],"A":[58],"broad":[59],"distribution":[61,83],"coiled-coils":[64],"has":[68],"been":[69],"quantified":[70],"combining":[72],"ATR-FTIR":[75],"measurements.":[76],"Error":[77],"analysis":[78],"for":[79],"such":[80,94],"deduced":[82],"was":[84],"carried":[85],"out.":[86],"This":[87],"research":[88],"demonstrates":[89],"quantitative":[91],"structural":[92],"information":[93],"orientational":[96],"conformational":[98],"ordering":[99],"proteins":[101],"interfaces":[103],"can":[104],"be":[105],"other":[111],"spectroscopic":[112],"techniques.":[113]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}