{"id":"https://openalex.org/W1980599321","doi":"https://doi.org/10.4103/0975-7406.94128","title":"Evaluation of cyclodextrins for enhancing corneal penetration of natamycin eye drops","display_name":"Evaluation of cyclodextrins for enhancing corneal penetration of natamycin eye drops","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W1980599321","doi":"https://doi.org/10.4103/0975-7406.94128","mag":"1980599321","pmid":"https://pubmed.ncbi.nlm.nih.gov/23066195","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3467818"},"language":"en","primary_location":{"id":"doi:10.4103/0975-7406.94128","doi":"https://doi.org/10.4103/0975-7406.94128","is_oa":true,"landing_page_url":"https://doi.org/10.4103/0975-7406.94128","pdf_url":null,"source":{"id":"https://openalex.org/S109681697","display_name":"Journal of Pharmacy And Bioallied Sciences","issn_l":"0975-7406","issn":["0975-7406","0976-4879"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmacy And Bioallied Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.4103/0975-7406.94128","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041554540","display_name":"Anjali Badhani","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Anjali Badhani","raw_affiliation_strings":["Department of Pharmacy, Gyani Inder Singh Institute of Professional Studies, Dehradun, Uttarakhand, India","Dr. Badhani Anjali, E-mail: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Gyani Inder Singh Institute of Professional Studies, Dehradun, Uttarakhand, India","institution_ids":[]},{"raw_affiliation_string":"Dr. Badhani Anjali, E-mail: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077902962","display_name":"Prashant Dabral","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Prashant Dabral","raw_affiliation_strings":["Department of Pharmacy, Gyani Inder Singh Institute of Professional Studies, Dehradun, Uttarakhand, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Gyani Inder Singh Institute of Professional Studies, Dehradun, Uttarakhand, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054456515","display_name":"Vinod Rana","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vinod Rana","raw_affiliation_strings":["Department of Pharmacy, Gyani Inder Singh Institute of Professional Studies, Dehradun, Uttarakhand, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Gyani Inder Singh Institute of Professional Studies, Dehradun, Uttarakhand, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044642083","display_name":"Kumud Upadhyaya","orcid":"https://orcid.org/0000-0002-5871-1708","observed_orcids":["https://orcid.org/0000-0002-5871-1708"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kumud Upadhyaya","raw_affiliation_strings":["Department of Pharmacy, Gyani Inder Singh Institute of Professional Studies, Dehradun, Uttarakhand, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Gyani Inder Singh Institute of Professional Studies, Dehradun, Uttarakhand, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5041554540"],"corresponding_institution_ids":[],"apc_list":{"value":250,"currency":"USD","value_usd":250},"apc_paid":{"value":250,"currency":"USD","value_usd":250},"fwci":0.6506,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.61266649,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"4","issue":"5","first_page":"29","last_page":"29"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.6855000257492065,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.6855000257492065,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.305400013923645,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyclodextrins","display_name":"cyclodextrins","score":0.9950000047683716},{"id":"https://openalex.org/keywords/natamycin","display_name":"natamycin","score":0.996999979019165},{"id":"https://openalex.org/keywords/eye-drops","display_name":"eye drops","score":0.8100000023841858},{"id":"https://openalex.org/keywords/corneal-penetration","display_name":"corneal penetration","score":0.8650000095367432},{"id":"https://openalex.org/keywords/inclusion-complexes","display_name":"inclusion complexes","score":0.7879999876022339},{"id":"https://openalex.org/keywords/aqueous-formulation","display_name":"aqueous formulation","score":0.6060000061988831},{"id":"https://openalex.org/keywords/poorly-water-soluble-drugs","display_name":"poorly water-soluble drugs","score":0.7839999794960022},{"id":"https://openalex.org/keywords/antifungal-agents","display_name":"antifungal agents","score":0.859000027179718},{"id":"https://openalex.org/keywords/pharmaceutical-excipients","display_name":"pharmaceutical excipients","score":0.6859999895095825}],"concepts":[{"id":"https://openalex.org/C2779117757","wikidata":"https://www.wikidata.org/wiki/Q248466","display_name":"Natamycin","level":2,"score":0.9525238275527954},{"id":"https://openalex.org/C155574463","wikidata":"https://www.wikidata.org/wiki/Q170731","display_name":"Solubility","level":2,"score":0.6649689674377441},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.5906858444213867},{"id":"https://openalex.org/C2779433975","wikidata":"https://www.wikidata.org/wiki/Q40417805","display_name":"Cyclodextrin","level":2,"score":0.5695421695709229},{"id":"https://openalex.org/C2777625524","wikidata":"https://www.wikidata.org/wiki/Q552308","display_name":"Eye drop","level":2,"score":0.5681984424591064},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5343832969665527},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5263979434967041},{"id":"https://openalex.org/C4863142","wikidata":"https://www.wikidata.org/wiki/Q907920","display_name":"Solubilization","level":2,"score":0.47155997157096863},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.4659505784511566},{"id":"https://openalex.org/C80107235","wikidata":"https://www.wikidata.org/wiki/Q7162625","display_name":"Penetration (warfare)","level":2,"score":0.4533781409263611},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.44601160287857056},{"id":"https://openalex.org/C2781345722","wikidata":"https://www.wikidata.org/wiki/Q5308388","display_name":"Drop (telecommunication)","level":2,"score":0.42381638288497925},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.256324827671051},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2534802556037903},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.15950819849967957},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1569872498512268},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.13581699132919312},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.13457632064819336},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.10383287072181702},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.08612802624702454},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07781487703323364},{"id":"https://openalex.org/C42475967","wikidata":"https://www.wikidata.org/wiki/Q194292","display_name":"Operations research","level":1,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.4103/0975-7406.94128","doi":"https://doi.org/10.4103/0975-7406.94128","is_oa":true,"landing_page_url":"https://doi.org/10.4103/0975-7406.94128","pdf_url":null,"source":{"id":"https://openalex.org/S109681697","display_name":"Journal of Pharmacy And Bioallied Sciences","issn_l":"0975-7406","issn":["0975-7406","0976-4879"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmacy And Bioallied Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3467818","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3467818/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3467818/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Pharm Bioallied Sci","raw_type":"Text"},{"id":"pmid:23066195","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23066195","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pharmacy & bioallied sciences","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:5a55142221fc4432b3f5a45de340c805","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/5a55142221fc4432b3f5a45de340c805","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Pharmacy and Bioallied Sciences, Vol 4, Iss 5, Pp 29-30 (2012)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4103/0975-7406.94128","doi":"https://doi.org/10.4103/0975-7406.94128","is_oa":true,"landing_page_url":"https://doi.org/10.4103/0975-7406.94128","pdf_url":null,"source":{"id":"https://openalex.org/S109681697","display_name":"Journal of Pharmacy And Bioallied Sciences","issn_l":"0975-7406","issn":["0975-7406","0976-4879"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pharmacy And Bioallied Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1980599321.pdf","grobid_xml":"https://content.openalex.org/works/W1980599321.grobid-xml"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W2156932023"],"related_works":["https://openalex.org/W2946612816","https://openalex.org/W4390033156","https://openalex.org/W4415314328","https://openalex.org/W4312117265","https://openalex.org/W1996743648","https://openalex.org/W3155874844","https://openalex.org/W1994438083","https://openalex.org/W3183845997","https://openalex.org/W2030650073","https://openalex.org/W7134033993"],"abstract_inverted_index":{"A":[0],"new":[1],"group":[2,20],"of":[3,21,49,78],"pharmaceutical":[4],"excipients":[5,22,53],"called":[6],"cyclodextrins":[7],"can":[8,80,96],"be":[9,36,73,97],"introduced":[10],"into":[11],"ophthalmology":[12],"for":[13],"delivering":[14],"such":[15],"water":[16,28],"insoluble":[17,29],"drug.":[18],"This":[19],"is":[23],"able":[24],"to":[25,35,82,99],"solubilize":[26],"many":[27],"drugs":[30],"which":[31],"were":[32,65],"previously":[33],"impossible":[34],"formulated":[37],"as":[38],"aqueous":[39,84],"eye":[40,87],"drop":[41],"solution":[42],"by":[43,54],"forming":[44],"their":[45],"inclusion":[46],"complexes.":[47],"Analysis":[48],"pure":[50],"drug":[51],"and":[52,62,94,102],"physical":[55],"test,":[56],"melting":[57],"point":[58],"determination,":[59],"chemical":[60],"test":[61],"solubility":[63],"determination":[64],"carried":[66],"out":[67],"in":[68],"this":[69],"study.":[70],"It":[71],"may":[72],"concluded":[74],"that":[75],"cyclodextrin":[76],"complexes":[77],"Natamycin":[79],"lead":[81],"an":[83],"formulation":[85],"(Natamycin":[86],"drop)":[88],"having":[89],"better":[90,103],"trans":[91],"corneal":[92],"permeability":[93],"thus":[95],"proved":[98],"have":[100],"faster":[101],"antifungal":[104],"efficiency.":[105]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}