{"id":"https://openalex.org/W1980409441","doi":"https://doi.org/10.1158/1538-7445.am10-3834","title":"Abstract 3834: Difference of host immunity and mucosal defense to H. pylori infection caused Asian paradox on incidence of gastric cancer: Correlation with mucosal mRNA expression of IL-8, pepsinogenI/II ratio, and H. pylori cagA gene mutation in Thai and Japanese gastric cancer","display_name":"Abstract 3834: Difference of host immunity and mucosal defense to H. pylori infection caused Asian paradox on incidence of gastric cancer: Correlation with mucosal mRNA expression of IL-8, pepsinogenI/II ratio, and H. pylori cagA gene mutation in Thai and Japanese gastric cancer","publication_year":2010,"publication_date":"2010-04-01","ids":{"openalex":"https://openalex.org/W1980409441","doi":"https://doi.org/10.1158/1538-7445.am10-3834","mag":"1980409441"},"language":"en","primary_location":{"id":"doi:10.1158/1538-7445.am10-3834","doi":"https://doi.org/10.1158/1538-7445.am10-3834","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am10-3834","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022686749","display_name":"Sirikan Limpakan Yamada","orcid":"https://orcid.org/0000-0001-6077-3011","observed_orcids":["https://orcid.org/0000-0001-6077-3011"]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Sirikan Yamada","raw_affiliation_strings":["1Chiang Mai University, Chiang Mai, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Chiang Mai University, Chiang Mai, Thailand","institution_ids":["https://openalex.org/I48076826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033380173","display_name":"Shunji Kato","orcid":"https://orcid.org/0000-0003-4659-9541","observed_orcids":["https://orcid.org/0000-0003-4659-9541"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shunji Kato","raw_affiliation_strings":["2Nippon Medical School, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Nippon Medical School, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072611129","display_name":"Takeshi Matsuhisa","orcid":"https://orcid.org/0000-0001-7376-8895","observed_orcids":["https://orcid.org/0000-0001-7376-8895"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeshi Matsuhisa","raw_affiliation_strings":["3Tama-Nagayama Hospital, Nippon Medical School, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Tama-Nagayama Hospital, Nippon Medical School, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057507540","display_name":"Luksana Makonkawkeyoon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Luksana Makonkawkeyoon","raw_affiliation_strings":["1Chiang Mai University, Chiang Mai, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Chiang Mai University, Chiang Mai, Thailand","institution_ids":["https://openalex.org/I48076826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072721635","display_name":"Thiraphat Charkrabandhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Thiraphat Charkrabandhu","raw_affiliation_strings":["1Chiang Mai University, Chiang Mai, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Chiang Mai University, Chiang Mai, Thailand","institution_ids":["https://openalex.org/I48076826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027629483","display_name":"Pawit Sutharat","orcid":"https://orcid.org/0009-0003-0714-7806","observed_orcids":["https://orcid.org/0009-0003-0714-7806"]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Pawit Sutharat","raw_affiliation_strings":["1Chiang Mai University, Chiang Mai, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Chiang Mai University, Chiang Mai, Thailand","institution_ids":["https://openalex.org/I48076826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070039166","display_name":"Nirush Lertprasertsuk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Nirush Lertprasertsuk","raw_affiliation_strings":["1Chiang Mai University, Chiang Mai, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Chiang Mai University, Chiang Mai, Thailand","institution_ids":["https://openalex.org/I48076826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042633177","display_name":"M Miki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaru Miki","raw_affiliation_strings":["2Nippon Medical School, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Nippon Medical School, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070386656","display_name":"Norio Matsukura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norio Matsukura","raw_affiliation_strings":["2Nippon Medical School, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Nippon Medical School, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112209642","display_name":"Masao Miyashita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masao Miyashita","raw_affiliation_strings":["2Nippon Medical School, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Nippon Medical School, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073274878","display_name":"Nobutaka Yamada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobutaka Yamada","raw_affiliation_strings":["2Nippon Medical School, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Nippon Medical School, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060893642","display_name":"Masaru Yoshida","orcid":"https://orcid.org/0000-0002-6905-8898","observed_orcids":["https://orcid.org/0000-0002-6905-8898"]},"institutions":[{"id":"https://openalex.org/I65837984","display_name":"Kobe University","ror":"https://ror.org/03tgsfw79","country_code":"JP","type":"education","lineage":["https://openalex.org/I65837984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaru Yoshida","raw_affiliation_strings":["4Kobe University School of Medicine, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Kobe University School of Medicine, Kobe, Japan","institution_ids":["https://openalex.org/I65837984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057083146","display_name":"Bandhuphat Chakrabandhu","orcid":"https://orcid.org/0000-0001-6299-6606","observed_orcids":["https://orcid.org/0000-0001-6299-6606"]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Bandhuphat Chakrabandhu","raw_affiliation_strings":["1Chiang Mai University, Chiang Mai, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Chiang Mai University, Chiang Mai, Thailand","institution_ids":["https://openalex.org/I48076826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069269152","display_name":"Worawit Khangtragool","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Worawit Khangtragool","raw_affiliation_strings":["1Chiang Mai University, Chiang Mai, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Chiang Mai University, Chiang Mai, Thailand","institution_ids":["https://openalex.org/I48076826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033853901","display_name":"Trichak Sundhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48076826","display_name":"Chiang Mai University","ror":"https://ror.org/05m2fqn25","country_code":"TH","type":"education","lineage":["https://openalex.org/I48076826"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Trichak Sundhu","raw_affiliation_strings":["1Chiang Mai University, Chiang Mai, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Chiang Mai University, Chiang Mai, Thailand","institution_ids":["https://openalex.org/I48076826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109896637","display_name":"Takashi Tajiri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi Tajiri","raw_affiliation_strings":["2Nippon Medical School, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Nippon Medical School, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020434543","display_name":"Takeshi Azuma","orcid":"https://orcid.org/0000-0002-4921-2122","observed_orcids":["https://orcid.org/0000-0002-4921-2122"]},"institutions":[{"id":"https://openalex.org/I65837984","display_name":"Kobe University","ror":"https://ror.org/03tgsfw79","country_code":"JP","type":"education","lineage":["https://openalex.org/I65837984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeshi Azuma","raw_affiliation_strings":["4Kobe University School of Medicine, Kobe, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Kobe University School of Medicine, Kobe, Japan","institution_ids":["https://openalex.org/I65837984"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"70","issue":"8_Supplement","first_page":"3834","last_page":"3834"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/helicobacter-pylori-infection","display_name":"Helicobacter pylori infection","score":0.9539999961853027},{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.9789999723434448},{"id":"https://openalex.org/keywords/host-immunity","display_name":"host immunity","score":0.8370000123977661},{"id":"https://openalex.org/keywords/mucosal-protection","display_name":"mucosal protection","score":0.9340000152587891},{"id":"https://openalex.org/keywords/il-8-mrna-expression","display_name":"IL-8 mRNA expression","score":0.9679999947547913},{"id":"https://openalex.org/keywords/pepsinogen-i-ii-ratio","display_name":"pepsinogen I/II ratio","score":0.9789999723434448},{"id":"https://openalex.org/keywords/host-defense-genes","display_name":"host defense genes","score":0.33799999952316284},{"id":"https://openalex.org/keywords/peptic-ulcer","display_name":"peptic ulcer","score":0.7590000033378601},{"id":"https://openalex.org/keywords/gastric-carcinogenesis","display_name":"gastric carcinogenesis","score":0.7200000286102295},{"id":"https://openalex.org/keywords/chronic-active-gastritis","display_name":"chronic active gastritis","score":0.7860000133514404},{"id":"https://openalex.org/keywords/gastric-mucosa","display_name":"gastric mucosa","score":0.42399999499320984}],"concepts":[{"id":"https://openalex.org/C2778204961","wikidata":"https://www.wikidata.org/wiki/Q83146136","display_name":"CagA","level":4,"score":0.7516483068466187},{"id":"https://openalex.org/C2780714494","wikidata":"https://www.wikidata.org/wiki/Q148925","display_name":"Thais","level":2,"score":0.7133011817932129},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.7111829519271851},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.6115777492523193},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5802695751190186},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.5477449893951416},{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.5332514643669128},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5319063663482666},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3236783742904663},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2676146626472473},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09958401322364807},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.07373592257499695},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1538-7445.am10-3834","doi":"https://doi.org/10.1158/1538-7445.am10-3834","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am10-3834","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2326980181","https://openalex.org/W3151031563","https://openalex.org/W7145475565","https://openalex.org/W2134093337","https://openalex.org/W2444435790","https://openalex.org/W2560994761","https://openalex.org/W2064506783","https://openalex.org/W1974915742","https://openalex.org/W2042681842","https://openalex.org/W2022046851"],"abstract_inverted_index":{"Abstract":[0],"Background:":[1],"Recent":[2],"in":[3,20,26,43,74,83,130,158,164,178,181,204,224,241,249,272,281,336,401,434,439],"vitro":[4],"studies":[5],"showed":[6,292,436],"the":[7,362,452,457],"association":[8,407],"between":[9,51,419],"mucosal":[10,56,427,437],"mRNA":[11,101,222,239,267,417,432],"expression":[12,102,223,240,268,392,418,433],"of":[13,71,155,196,201,210,220,237,265,288,297,315,320,356,366,451,456],"IL-8":[14,99,221,238,266,298,390,416,431],"with":[15,284,301,352,370],"cagA,":[16,373],"East":[17],"Asian":[18],"type":[19],"gastric":[21,32,75,90,97,166,183,189,402,440],"cancer":[22,91,157,167,190,226,229,243,441],"that":[23,47,389],"frequently":[24],"found":[25],"Japanese.":[27,44],"In":[28,255,309,361,383],"Thais,":[29,84],"not":[30,260,330],"only":[31,340],"cancer,":[33,184],"but":[34],"also":[35,246,406],"gastroduodenal":[36],"ulcer":[37],"incidences":[38],"are":[39],"opposite":[40,413],"to":[41,60,67,332,379,408,423],"those":[42],"We":[45],"hypothesized":[46],"an":[48],"associations":[49],"difference":[50,149],"Thais":[52,435],"and":[53,85,88,96,118,153,209,227,232,274,323,350],"Japanese":[54,89,179,228],"stomach":[55,131,426],"tissue":[57],"cytokine":[58,100,391],"response":[59],"H.":[61,114,123,161,277,346,357,371],"pylori":[62,124,162,278,347,358,372],"infection":[63],"may":[64],"lead":[65],"us":[66],"find":[68],"key":[69],"role":[70],"host":[72,425],"defense":[73,438],"carcinogenesis.":[76,442],"Method:":[77],"There":[78,171,338,404],"were":[79,120,230],"143":[80],"non-cancer":[81,250],"volunteers":[82],"110":[86],"Thai":[87,165,182,188,225,242,310,367],"patients":[92,191],"who":[93,343],"underwent":[94],"endoscopy":[95],"surgery.":[98],"was":[103,132,140,168,339],"conducted":[104],"by":[105,150,348],"real":[106],"time":[107],"RT-PCR.":[108],"Histopathology,":[109],"serum":[110],"IgG":[111,359],"antibody":[112],"for":[113,134,397,460],"pylori,":[115],"pepsinogen":[116],"I":[117],"II":[119],"tested.":[121],"Tissue":[122],"DNA":[125],"extracted":[126],"from":[127],"antral":[128],"position":[129],"genotyped":[133],"cagA":[135,312],"mutation.":[136],"p":[137,185,207,216,252,306],"value":[138],"<0.05":[139],"considered":[141],"as":[142],"a":[143,173,262,293,353,394],"statistically":[144],"significant.":[145],"Result:":[146],"No":[147],"distribution":[148],"sex,":[151],"age,":[152],"stage":[154],"advance":[156],"both":[159,420],"nations.":[160],"positivity":[163,273],"70.5%":[169],"(55/78).":[170],"is":[172,245,393,405],"significant":[174,294],"lower":[175,194],"PGI/II":[176,270,289,302,327,410],"ratio":[177,198,271,291,303,328],"than":[180,203,248,286,300],"=":[186,253],"0.026.":[187],"had":[192,344],"significantly":[193,263],"level":[195,219,236,296,430],"PGII/II":[197],"at":[199],"means":[200],"3.3\u00b11.7":[202],"normal":[205],"one,":[206],"=0.042,":[208],"other":[211],"non-chronic":[212],"active":[213],"gastritis":[214],"(CAG),":[215],"=0.002.":[217],"Means":[218,235],"8511.36\u00b15.22":[231],"174.54\u00b1329.51,":[233],"respectively.":[234],"group":[244,369],"higher":[247,295],"group,":[251],"0.058.":[254],"subgroup":[256],"analysis,":[257],"we":[258,387],"could":[259],"see":[261],"differences":[264],"or":[269],"true":[275],"negativity":[276],"infection.":[279],"However,":[280],"positive":[282,345],"cases":[283],"less":[285],"2.0":[287],"low":[290,409],"expressions":[299],"over":[304],"3.0,":[305],"<":[307],"0.05.":[308],"non-cancer,":[311],"genotype":[313],"yield":[314],"33":[316],"per":[317],"cent":[318],"each":[319],"Eastern,":[321],"Western,":[322],"Mix":[324],"type.":[325],"Low":[326],"did":[329],"associate":[331],"CAG":[333,368],"severity":[334],"score":[335],"Thais.":[337],"32/55":[341],"(58%)":[342],"PCR":[349],"pathology":[351],"rising":[354],"up":[355,365],"antibody.":[360],"6-year":[363],"followed":[364],"Eastern":[374],"infection,":[375],"no":[376],"one":[377],"develop":[378],"be":[380],"cancer.":[381,403],"Conclusion:":[382],"this":[384],"vivo":[385],"study,":[386],"postulated":[388],"predictive":[395],"marker":[396],"poor":[398],"prognosis":[399],"incidence":[400],"ratio.":[411],"The":[412],"result":[414],"on":[415],"nations":[421],"reflex":[422],"individualized":[424],"defense.":[428],"High":[429],"Citation":[443],"Format:":[444],"{Authors}.":[445],"{Abstract":[446],"title}":[447],"[abstract].":[448],"In:":[449],"Proceedings":[450],"101st":[453],"Annual":[454],"Meeting":[455],"American":[458],"Association":[459],"Cancer":[461,471],"Research;":[462],"2010":[463],"Apr":[464],"17-21;":[465],"Washington,":[466],"DC.":[467],"Philadelphia":[468],"(PA):":[469],"AACR;":[470],"Res":[472],"2010;70(8":[473],"Suppl):Abstract":[474],"nr":[475],"3834.":[476]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}