{"id":"https://openalex.org/W1980196562","doi":"https://doi.org/10.1016/0002-9343(87)90873-4","title":"Changes in lipoprotein kinetics during therapy with fenofibrate and other fibric acid derivatives","display_name":"Changes in lipoprotein kinetics during therapy with fenofibrate and other fibric acid derivatives","publication_year":1987,"publication_date":"1987-11-01","ids":{"openalex":"https://openalex.org/W1980196562","doi":"https://doi.org/10.1016/0002-9343(87)90873-4","mag":"1980196562","pmid":"https://pubmed.ncbi.nlm.nih.gov/3318456"},"language":"en","primary_location":{"id":"doi:10.1016/0002-9343(87)90873-4","doi":"https://doi.org/10.1016/0002-9343(87)90873-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0002-9343(87)90873-4","pdf_url":null,"source":{"id":"https://openalex.org/S186920367","display_name":"The American Journal of Medicine","issn_l":"0002-9343","issn":["0002-9343","1555-7162"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007048045","display_name":"Henry N. Ginsberg","orcid":"https://orcid.org/0000-0002-4103-3592","observed_orcids":["https://orcid.org/0000-0002-4103-3592"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Henry N. Ginsberg","raw_affiliation_strings":["Columbia University College of Physicians and Surgeons, Department of Medicine, New York, New York 10032"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University College of Physicians and Surgeons, Department of Medicine, New York, New York 10032","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5007048045"],"corresponding_institution_ids":["https://openalex.org/I78577930"],"apc_list":{"value":3770,"currency":"USD","value_usd":3770},"apc_paid":null,"fwci":1.0861,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.76509164,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"83","issue":"5","first_page":"66","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.6039999723434448,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.6039999723434448,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.37790000438690186,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.015300000086426735,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fenofibrate","display_name":"fenofibrate","score":0.9710000157356262},{"id":"https://openalex.org/keywords/fibrates","display_name":"fibrates","score":0.9639999866485596},{"id":"https://openalex.org/keywords/lipoprotein-kinetics","display_name":"lipoprotein kinetics","score":0.8650000095367432},{"id":"https://openalex.org/keywords/very-low-density-lipoprotein","display_name":"VLDL","score":0.8830000162124634},{"id":"https://openalex.org/keywords/low-density-lipoprotein","display_name":"low-density lipoprotein","score":0.8009999990463257},{"id":"https://openalex.org/keywords/high-density-lipoprotein","display_name":"high-density lipoprotein","score":0.8420000076293945},{"id":"https://openalex.org/keywords/lipoprotein-lipase","display_name":"lipoprotein lipase","score":0.9440000057220459},{"id":"https://openalex.org/keywords/hepatic-vldl-secretion","display_name":"hepatic VLDL secretion","score":0.7350000143051147},{"id":"https://openalex.org/keywords/hypertriglyceridemia","display_name":"hypertriglyceridemia","score":0.8330000042915344},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/apolipoprotein-a-i","display_name":"apolipoprotein A-I","score":0.8709999918937683},{"id":"https://openalex.org/keywords/lipid-lowering-therapy","display_name":"lipid-lowering therapy","score":0.6930000185966492}],"concepts":[{"id":"https://openalex.org/C2778110834","wikidata":"https://www.wikidata.org/wiki/Q419724","display_name":"Fenofibrate","level":2,"score":0.8887513875961304},{"id":"https://openalex.org/C2776933373","wikidata":"https://www.wikidata.org/wiki/Q424744","display_name":"Fibrate","level":3,"score":0.7530818581581116},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6939333081245422},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.6864710450172424},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6847473978996277},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6816311478614807},{"id":"https://openalex.org/C94879076","wikidata":"https://www.wikidata.org/wiki/Q420014","display_name":"Lipoprotein lipase","level":3,"score":0.5858417749404907},{"id":"https://openalex.org/C2776919658","wikidata":"https://www.wikidata.org/wiki/Q1467339","display_name":"Hypertriglyceridemia","level":4,"score":0.550705075263977},{"id":"https://openalex.org/C2779620165","wikidata":"https://www.wikidata.org/wiki/Q28749","display_name":"Low-density lipoprotein","level":3,"score":0.5186097621917725},{"id":"https://openalex.org/C8243546","wikidata":"https://www.wikidata.org/wiki/Q419074","display_name":"Very low-density lipoprotein","level":4,"score":0.500906229019165},{"id":"https://openalex.org/C174782155","wikidata":"https://www.wikidata.org/wiki/Q18032613","display_name":"Low-density lipoprotein receptor-related protein 8","level":5,"score":0.48987239599227905},{"id":"https://openalex.org/C96942376","wikidata":"https://www.wikidata.org/wiki/Q21130714","display_name":"Catabolism","level":3,"score":0.4333617091178894},{"id":"https://openalex.org/C2780541478","wikidata":"https://www.wikidata.org/wiki/Q410020","display_name":"High-density lipoprotein","level":3,"score":0.42101404070854187},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.4114112854003906},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.245448499917984},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.1291821002960205},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.049830853939056396}],"mesh":[{"descriptor_ui":"D000924","descriptor_name":"Anticholesteremic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001053","descriptor_name":"Apolipoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002994","descriptor_name":"Clofibrate","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D002994","descriptor_name":"Clofibrate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008071","descriptor_name":"Lipoprotein Lipase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008077","descriptor_name":"Lipoproteins, LDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008079","descriptor_name":"Lipoproteins, VLDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011345","descriptor_name":"Fenofibrate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011422","descriptor_name":"Propionates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0002-9343(87)90873-4","doi":"https://doi.org/10.1016/0002-9343(87)90873-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0002-9343(87)90873-4","pdf_url":null,"source":{"id":"https://openalex.org/S186920367","display_name":"The American Journal of Medicine","issn_l":"0002-9343","issn":["0002-9343","1555-7162"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Medicine","raw_type":"journal-article"},{"id":"pmid:3318456","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3318456","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W2000519468","https://openalex.org/W2010913819","https://openalex.org/W2030155302","https://openalex.org/W2076809869","https://openalex.org/W2109073239","https://openalex.org/W2144198808","https://openalex.org/W2146966629","https://openalex.org/W4238037042"],"related_works":["https://openalex.org/W1973739555","https://openalex.org/W2146966629","https://openalex.org/W2056842360","https://openalex.org/W2161048144","https://openalex.org/W1028515009","https://openalex.org/W2416346772","https://openalex.org/W2029720301","https://openalex.org/W2416311034","https://openalex.org/W1991233352","https://openalex.org/W2026602634"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}