{"id":"https://openalex.org/W1980090585","doi":"https://doi.org/10.1002/syn.20048","title":"Identification and characterization of a novel allosteric modulator (SoRI\u20106238) of the serotonin transporter","display_name":"Identification and characterization of a novel allosteric modulator (SoRI\u20106238) of the serotonin transporter","publication_year":2004,"publication_date":"2004-06-22","ids":{"openalex":"https://openalex.org/W1980090585","doi":"https://doi.org/10.1002/syn.20048","mag":"1980090585","pmid":"https://pubmed.ncbi.nlm.nih.gov/15236350"},"language":"en","primary_location":{"id":"doi:10.1002/syn.20048","doi":"https://doi.org/10.1002/syn.20048","is_oa":false,"landing_page_url":"https://doi.org/10.1002/syn.20048","pdf_url":null,"source":{"id":"https://openalex.org/S158211696","display_name":"Synapse","issn_l":"0887-4476","issn":["0887-4476","1098-2396"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synapse","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079953860","display_name":"Ayon Nandi","orcid":"https://orcid.org/0000-0002-1549-8900","observed_orcids":["https://orcid.org/0000-0002-1549-8900"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I1327069482","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I1327069482"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ayon Nandi","raw_affiliation_strings":["Clinical Psychopharmacology Section, Intramural Research Program, National Institute of Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Psychopharmacology Section, Intramural Research Program, National Institute of Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I1327069482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014962738","display_name":"Christina M. Dersch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1327069482","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I1327069482"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christina M. Dersch","raw_affiliation_strings":["Clinical Psychopharmacology Section, IRP, NIDA, NIH, Baltimore, Maryland 21224"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Psychopharmacology Section, IRP, NIDA, NIH, Baltimore, Maryland 21224","institution_ids":["https://openalex.org/I1327069482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016214796","display_name":"Mukul Kulshrestha","orcid":"https://orcid.org/0000-0002-3917-6324","observed_orcids":["https://orcid.org/0000-0002-3917-6324"]},"institutions":[{"id":"https://openalex.org/I108109523","display_name":"Southern Research Institute","ror":"https://ror.org/0153ngy95","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I108109523"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Manish Kulshrestha","raw_affiliation_strings":["Organic Chemistry Department, Southern Research Institute, Birmingham, Alabama 35255"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organic Chemistry Department, Southern Research Institute, Birmingham, Alabama 35255","institution_ids":["https://openalex.org/I108109523"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006585063","display_name":"Subramaniam Ananthan","orcid":"https://orcid.org/0000-0002-4791-9116","observed_orcids":["https://orcid.org/0000-0002-4791-9116"]},"institutions":[{"id":"https://openalex.org/I108109523","display_name":"Southern Research Institute","ror":"https://ror.org/0153ngy95","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I108109523"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Subramaniam Ananthan","raw_affiliation_strings":["Organic Chemistry Department, Southern Research Institute, Birmingham, Alabama 35255"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organic Chemistry Department, Southern Research Institute, Birmingham, Alabama 35255","institution_ids":["https://openalex.org/I108109523"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103446078","display_name":"Richard B. Rothman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I1327069482","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I1327069482"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Richard B. Rothman","raw_affiliation_strings":["Clinical Psychopharmacology Section, IRP, NIDA, NIH, Baltimore, Maryland 21224","Clinical Psychopharmacology Section, IRP, NIDA, NIH, Baltimore, MD 21224"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Psychopharmacology Section, IRP, NIDA, NIH, Baltimore, Maryland 21224","institution_ids":["https://openalex.org/I1327069482"]},{"raw_affiliation_string":"Clinical Psychopharmacology Section, IRP, NIDA, NIH, Baltimore, MD 21224","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I1327069482"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5103446078"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I1327069482"],"apc_list":{"value":3570,"currency":"USD","value_usd":3570},"apc_paid":null,"fwci":0.8206,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.63858574,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"53","issue":"3","first_page":"176","last_page":"183"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.8906000256538391,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.8906000256538391,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0820000022649765,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serotonin-transporter","display_name":"serotonin transporter","score":0.9860000014305115},{"id":"https://openalex.org/keywords/allosteric-modulation","display_name":"allosteric modulation","score":0.906000018119812},{"id":"https://openalex.org/keywords/non-competitive-inhibition","display_name":"non-competitive inhibition","score":0.8889999985694885},{"id":"https://openalex.org/keywords/norepinephrine-transporter","display_name":"norepinephrine transporter","score":0.9020000100135803},{"id":"https://openalex.org/keywords/dopamine-transporter","display_name":"dopamine transporter","score":1.0},{"id":"https://openalex.org/keywords/serotonin-uptake","display_name":"serotonin uptake","score":0.6800000071525574}],"concepts":[{"id":"https://openalex.org/C2778897192","wikidata":"https://www.wikidata.org/wiki/Q410142","display_name":"Serotonin transporter","level":4,"score":0.8324860334396362},{"id":"https://openalex.org/C166342909","wikidata":"https://www.wikidata.org/wiki/Q845326","display_name":"Allosteric regulation","level":3,"score":0.7936907410621643},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6158881783485413},{"id":"https://openalex.org/C2776038425","wikidata":"https://www.wikidata.org/wiki/Q2649417","display_name":"Allosteric modulator","level":4,"score":0.5870038270950317},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.5655126571655273},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5126820802688599},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.4756952226161957},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4151266813278198},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3795057237148285},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3280297815799713},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2846604883670807},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.27362141013145447},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.21468546986579895},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12668359279632568},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000494","descriptor_name":"Allosteric Regulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000494","descriptor_name":"Allosteric Regulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001667","descriptor_name":"Binding, Competitive","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001667","descriptor_name":"Binding, Competitive","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001923","descriptor_name":"Brain Chemistry","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001923","descriptor_name":"Brain Chemistry","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002219","descriptor_name":"Carbamates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002219","descriptor_name":"Carbamates","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011719","descriptor_name":"Pyrazines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011719","descriptor_name":"Pyrazines","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D011869","descriptor_name":"Radioligand Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013347","descriptor_name":"Subcellular Fractions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014179","descriptor_name":"Neurotransmitter Uptake Inhibitors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014179","descriptor_name":"Neurotransmitter Uptake Inhibitors","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D027981","descriptor_name":"Symporters","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D027981","descriptor_name":"Symporters","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050483","descriptor_name":"Dopamine Plasma Membrane Transport Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050484","descriptor_name":"Norepinephrine Plasma Membrane Transport Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050486","descriptor_name":"Serotonin Plasma Membrane Transport Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/syn.20048","doi":"https://doi.org/10.1002/syn.20048","is_oa":false,"landing_page_url":"https://doi.org/10.1002/syn.20048","pdf_url":null,"source":{"id":"https://openalex.org/S158211696","display_name":"Synapse","issn_l":"0887-4476","issn":["0887-4476","1098-2396"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synapse","raw_type":"journal-article"},{"id":"pmid:15236350","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15236350","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synapse (New York, N.Y.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W30321165","https://openalex.org/W1767184367","https://openalex.org/W1858777777","https://openalex.org/W1886012028","https://openalex.org/W1971858313","https://openalex.org/W1975212667","https://openalex.org/W1975912352","https://openalex.org/W1996096162","https://openalex.org/W1997460720","https://openalex.org/W2010500572","https://openalex.org/W2019551094","https://openalex.org/W2067641008","https://openalex.org/W2111112265","https://openalex.org/W2138117456","https://openalex.org/W2145533695","https://openalex.org/W2159821201","https://openalex.org/W2254167015"],"related_works":["https://openalex.org/W1995593325","https://openalex.org/W2171604337","https://openalex.org/W2163694515","https://openalex.org/W2029715506","https://openalex.org/W2060133037","https://openalex.org/W2555493310","https://openalex.org/W2162163141","https://openalex.org/W2073471016","https://openalex.org/W2013832113","https://openalex.org/W4387344091"],"abstract_inverted_index":{"In":[0,97],"the":[1,93,102,110],"present":[2],"study":[3],"we":[4],"describe":[5],"a":[6,39,78],"novel":[7],"agent,":[8],"SoRI-6238":[9,30,46,85,100,117],"(ethyl":[10],"5-amino-3-(3,4-dichlorophenyl)-1,2-dihydropyrido[3,4-b]pyrazin-7-ylcarbamate)":[11],"that":[12,116],"partially":[13,31,118],"inhibits":[14,119],"5-HT":[15],"transporter":[16,50,54],"(SERT)":[17],"binding":[18,34,56,72,121],"and":[19,52,63,108,122],"allosterically":[20],"modulates":[21],"SERT":[22,33,74,107,120],"function.":[23],"Membranes":[24],"were":[25],"prepared":[26],"from":[27,106],"rat":[28],"brain.":[29],"inhibited":[32,48,87],"to":[35,73,91],"brain":[36],"membranes":[37],"with":[38,57,80],"plateau":[40,79],"at":[41],"about":[42],"40%":[43],"of":[44,60,70,83,104],"control.":[45],"fully":[47,86],"norepinephrine":[49],"(NET)":[51],"dopamine":[53],"(DAT)":[55],"IC(50)":[58],"values":[59],"12.1":[61],"microM":[62],"5.8":[64],"microM,":[65],"respectively.":[66],"The":[67],"apparent":[68],"K(d)":[69],"[(125)I]RTI-55":[71,105],"increased,":[75],"then":[76],"reached":[77],"increasing":[81],"concentrations":[82],"SoRI-6238.":[84],"[(3)H]5-HT":[88],"uptake,":[89],"acting":[90],"decrease":[92],"V(max)":[94],"(noncompetitive":[95],"inhibition).":[96],"kinetic":[98],"experiments,":[99],"slowed":[101,109],"dissociation":[103],"initial":[111],"association":[112],"rate.":[113],"We":[114],"conclude":[115],"function,":[123],"most":[124],"likely":[125],"via":[126],"an":[127],"allosteric":[128],"mechanism.":[129]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}