{"id":"https://openalex.org/W1979908066","doi":"https://doi.org/10.1002/dvdy.22309","title":"Pax2 is expressed in a subpopulation of M\u00fcller cells in the central chick retina","display_name":"Pax2 is expressed in a subpopulation of M\u00fcller cells in the central chick retina","publication_year":2010,"publication_date":"2010-04-23","ids":{"openalex":"https://openalex.org/W1979908066","doi":"https://doi.org/10.1002/dvdy.22309","mag":"1979908066","pmid":"https://pubmed.ncbi.nlm.nih.gov/20503381"},"language":"en","primary_location":{"id":"doi:10.1002/dvdy.22309","doi":"https://doi.org/10.1002/dvdy.22309","is_oa":true,"landing_page_url":"https://doi.org/10.1002/dvdy.22309","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/dvdy.22309","source":{"id":"https://openalex.org/S104993753","display_name":"Developmental Dynamics","issn_l":"1058-8388","issn":["1058-8388","1097-0177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Dynamics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/dvdy.22309","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071306774","display_name":"Henrik Boije","orcid":"https://orcid.org/0000-0002-4877-9725","observed_orcids":["https://orcid.org/0000-0002-4877-9725"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Henrik Boije","raw_affiliation_strings":["Department of Neuroscience, Biomedical Centre, Uppsala University, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Biomedical Centre, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091744913","display_name":"Henrik Ring","orcid":"https://orcid.org/0000-0002-7659-9043","observed_orcids":["https://orcid.org/0000-0002-7659-9043"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Henrik Ring","raw_affiliation_strings":["Department of Neuroscience, Biomedical Centre, Uppsala University, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Biomedical Centre, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003071563","display_name":"Meritxell L\u00f3pez\u2010Gallardo","orcid":"https://orcid.org/0000-0002-9291-623X","observed_orcids":["https://orcid.org/0000-0002-9291-623X"]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Meritxell L\u00f3pez\u2010Gallardo","raw_affiliation_strings":["Departamento de Fisiologi\u0301a, Facultad de Medicina, Universidad Complutense, Madrid, Espan\u0303a","Departamento de Fisiolog\u00eda, Facultad de Medicina, Universidad Complutense, Madrid, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Fisiologi\u0301a, Facultad de Medicina, Universidad Complutense, Madrid, Espan\u0303a","institution_ids":["https://openalex.org/I121748325"]},{"raw_affiliation_string":"Departamento de Fisiolog\u00eda, Facultad de Medicina, Universidad Complutense, Madrid, Espa\u00f1a","institution_ids":["https://openalex.org/I121748325"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Carmen Prada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Carmen Prada","raw_affiliation_strings":["Departamento de Fisiologi\u0301a, Facultad de Medicina, Universidad Complutense, Madrid, Espan\u0303a","Departamento de Fisiolog\u00eda, Facultad de Medicina, Universidad Complutense, Madrid, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Fisiologi\u0301a, Facultad de Medicina, Universidad Complutense, Madrid, Espan\u0303a","institution_ids":["https://openalex.org/I121748325"]},{"raw_affiliation_string":"Departamento de Fisiolog\u00eda, Facultad de Medicina, Universidad Complutense, Madrid, Espa\u00f1a","institution_ids":["https://openalex.org/I121748325"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037351715","display_name":"Finn Hallb\u00f6\u00f6k","orcid":"https://orcid.org/0000-0001-7552-187X","observed_orcids":["https://orcid.org/0000-0001-7552-187X"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Finn Hallb\u00f6\u00f6k","raw_affiliation_strings":["Department of Neuroscience, Biomedical Centre, Uppsala University, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Biomedical Centre, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5037351715"],"corresponding_institution_ids":["https://openalex.org/I123387679"],"apc_list":{"value":4430,"currency":"USD","value_usd":4430},"apc_paid":null,"fwci":2.6922,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.87841578,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"239","issue":"6","first_page":"1858","last_page":"1866"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pax2","display_name":"PAX2","score":0.9890000224113464},{"id":"https://openalex.org/keywords/muller-cells","display_name":"M\u00fcller cells","score":0.9919999837875366},{"id":"https://openalex.org/keywords/chick-retina","display_name":"chick retina","score":0.8349999785423279},{"id":"https://openalex.org/keywords/retinal-development","display_name":"retinal development","score":0.6669999957084656},{"id":"https://openalex.org/keywords/sox2","display_name":"SOX2","score":0.6150000095367432},{"id":"https://openalex.org/keywords/species-comparison","display_name":"species comparison","score":0.6299999952316284},{"id":"https://openalex.org/keywords/zebrafish-retina","display_name":"zebrafish retina","score":0.9089999794960022},{"id":"https://openalex.org/keywords/transcription-factor-expression","display_name":"transcription factor expression","score":0.6940000057220459}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9127554297447205},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.8005048036575317},{"id":"https://openalex.org/C2777933648","wikidata":"https://www.wikidata.org/wiki/Q21114866","display_name":"SOX2","level":4,"score":0.5734628438949585},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.5184266567230225},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5041650533676147},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.4859515428543091},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4587417542934418},{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.45085400342941284},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.44902902841567993},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4154791533946991},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.16514438390731812},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1626797914505005},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13110193610191345},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002477","descriptor_name":"Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002642","descriptor_name":"Chick Embryo","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009457","descriptor_name":"Neuroglia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016202","descriptor_name":"N-Methylaspartate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D026603","descriptor_name":"D-Aspartic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051762","descriptor_name":"PAX2 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/dvdy.22309","doi":"https://doi.org/10.1002/dvdy.22309","is_oa":true,"landing_page_url":"https://doi.org/10.1002/dvdy.22309","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/dvdy.22309","source":{"id":"https://openalex.org/S104993753","display_name":"Developmental Dynamics","issn_l":"1058-8388","issn":["1058-8388","1097-0177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Dynamics","raw_type":"journal-article"},{"id":"pmid:20503381","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20503381","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental dynamics : an official publication of the American Association of Anatomists","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/dvdy.22309","doi":"https://doi.org/10.1002/dvdy.22309","is_oa":true,"landing_page_url":"https://doi.org/10.1002/dvdy.22309","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/dvdy.22309","source":{"id":"https://openalex.org/S104993753","display_name":"Developmental Dynamics","issn_l":"1058-8388","issn":["1058-8388","1097-0177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Dynamics","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1979908066.pdf","grobid_xml":"https://content.openalex.org/works/W1979908066.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1794350917","https://openalex.org/W1822449379","https://openalex.org/W1881148963","https://openalex.org/W1895565798","https://openalex.org/W1966693486","https://openalex.org/W1969381388","https://openalex.org/W1987865684","https://openalex.org/W1996070625","https://openalex.org/W2004381049","https://openalex.org/W2005115709","https://openalex.org/W2006085438","https://openalex.org/W2008277743","https://openalex.org/W2015966587","https://openalex.org/W2016508121","https://openalex.org/W2022116045","https://openalex.org/W2035222904","https://openalex.org/W2038742877","https://openalex.org/W2042744803","https://openalex.org/W2043579544","https://openalex.org/W2054152543","https://openalex.org/W2054772371","https://openalex.org/W2057879292","https://openalex.org/W2062942585","https://openalex.org/W2070204274","https://openalex.org/W2084644999","https://openalex.org/W2094999649","https://openalex.org/W2102428207","https://openalex.org/W2103272211","https://openalex.org/W2104073051","https://openalex.org/W2105947076","https://openalex.org/W2109876648","https://openalex.org/W2112645512","https://openalex.org/W2115154324","https://openalex.org/W2131416478","https://openalex.org/W2140034535","https://openalex.org/W2146262948","https://openalex.org/W2151445759","https://openalex.org/W2164806284","https://openalex.org/W2167546055","https://openalex.org/W2422172409","https://openalex.org/W4299395343"],"related_works":["https://openalex.org/W1988319545","https://openalex.org/W7098185480","https://openalex.org/W2061742377","https://openalex.org/W7100831640","https://openalex.org/W2089131677","https://openalex.org/W2014579714","https://openalex.org/W2103124505","https://openalex.org/W2969860580","https://openalex.org/W81760616","https://openalex.org/W4323651779"],"abstract_inverted_index":{"M\u00fcller":[0,24,51,66,101,124,145],"cells":[1,25,52,102,125],"in":[2,26,91,110,123,126],"the":[3,17,27,47,76,80,92,96,99,111,135],"chick":[4,29],"retina":[5,30,112,137],"are":[6,53],"generally":[7],"thought":[8],"to":[9,107],"be":[10,104],"a":[11,139],"homogeneous":[12],"population.":[13],"We":[14],"show":[15],"that":[16,46],"transcription":[18],"factor":[19],"Pax2":[20,81,119],"is":[21],"expressed":[22],"by":[23,114],"central":[28,143],"and":[31,58,72],"its":[32],"expression":[33],"was":[34,89,120],"first":[35],"observed":[36],"at":[37],"stage":[38,56,62],"32":[39],"(embryonic":[40],"day":[41],"[E]":[42],"7.5).":[43],"Birth-dating":[44],"indicated":[45],"majority":[48],"of":[49,142],"Pax2-positive":[50,97],"generated":[54],"between":[55],"29":[57],"33":[59],"(E5.5-E8).":[60],"At":[61],"42":[63],"(E16),":[64],"several":[65],"cell":[67],"markers,":[68],"such":[69],"as":[70],"Sox2":[71],"2M6,":[73],"had":[74],"reached":[75],"peripheral":[77],"retina,":[78],"while":[79],"labeling":[82],"extended":[83],"approximately":[84],"half-way.":[85],"A":[86],"similar":[87,140],"pattern":[88,141],"maintained":[90],"6-month-old":[93],"chicken.":[94],"Neither":[95],"nor":[98],"Pax2-negative":[100],"could":[103],"specifically":[105],"associated":[106],"proliferative":[108],"responses":[109],"induced":[113],"growth":[115],"factors":[116],"or":[117,131],"N-methyl-D-aspartate.":[118],"not":[121],"detected":[122],"mouse,":[127],"rat,":[128],"guinea-pig,":[129],"rabbit,":[130],"pig":[132],"retinas;":[133],"but":[134],"zebrafish":[136],"displayed":[138],"Pax2-expressing":[144],"cells.":[146]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}