{"id":"https://openalex.org/W1978976540","doi":"https://doi.org/10.1016/0167-4838(91)90563-f","title":"Beware of proteins in DMSO","display_name":"Beware of proteins in DMSO","publication_year":1991,"publication_date":"1991-06-01","ids":{"openalex":"https://openalex.org/W1978976540","doi":"https://doi.org/10.1016/0167-4838(91)90563-f","mag":"1978976540","pmid":"https://pubmed.ncbi.nlm.nih.gov/2065090"},"language":"en","primary_location":{"id":"doi:10.1016/0167-4838(91)90563-f","doi":"https://doi.org/10.1016/0167-4838(91)90563-f","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0167-4838(91)90563-f","pdf_url":null,"source":{"id":"https://openalex.org/S4394735818","display_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","issn_l":"0167-4838","issn":["0167-4838","1879-2588"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W1978976540"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006034052","display_name":"Michael Jackson","orcid":"https://orcid.org/0000-0002-4730-201X","observed_orcids":["https://orcid.org/0000-0002-4730-201X"]},"institutions":[{"id":"https://openalex.org/I4210135718","display_name":"Steacie Institute for Molecular Sciences","ror":"https://ror.org/02tjxem41","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4210135718","https://openalex.org/I4210159778"]},{"id":"https://openalex.org/I4210159778","display_name":"National Research Council Canada","ror":"https://ror.org/04mte1k06","country_code":"CA","type":"government","lineage":["https://openalex.org/I4210159778"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Michael Jackson","raw_affiliation_strings":["Steacie Institute for Molecular Sciences, National Research Council of Canada, Ottawa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Steacie Institute for Molecular Sciences, National Research Council of Canada, Ottawa","institution_ids":["https://openalex.org/I4210135718","https://openalex.org/I4210159778"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111625517","display_name":"Henry H. Mantsch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210135718","display_name":"Steacie Institute for Molecular Sciences","ror":"https://ror.org/02tjxem41","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4210135718","https://openalex.org/I4210159778"]},{"id":"https://openalex.org/I4210159778","display_name":"National Research Council Canada","ror":"https://ror.org/04mte1k06","country_code":"CA","type":"government","lineage":["https://openalex.org/I4210159778"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Henry H. Mantsch","raw_affiliation_strings":["Steacre Institute for Molecular Sciences, National Research Council of Canada, Ottawa Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Steacre Institute for Molecular Sciences, National Research Council of Canada, Ottawa Canada","institution_ids":["https://openalex.org/I4210135718","https://openalex.org/I4210159778"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5111625517"],"corresponding_institution_ids":["https://openalex.org/I4210135718","https://openalex.org/I4210159778"],"apc_list":null,"apc_paid":null,"fwci":2.1138,"has_fulltext":false,"cited_by_count":269,"citation_normalized_percentile":{"value":0.87719254,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"1078","issue":"2","first_page":"231","last_page":"235"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.010599999688565731,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11177","display_name":"Spectroscopy and Quantum Chemical Studies","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dimethyl-sulfoxide","display_name":"dimethyl sulfoxide","score":0.8830000162124634},{"id":"https://openalex.org/keywords/protein-secondary-structure","display_name":"protein secondary structure","score":0.9269999861717224},{"id":"https://openalex.org/keywords/protein-unfolding","display_name":"protein unfolding","score":0.5640000104904175},{"id":"https://openalex.org/keywords/myoglobin","display_name":"myoglobin","score":0.8349999785423279},{"id":"https://openalex.org/keywords/concanavalin-a","display_name":"concanavalin A","score":1.0},{"id":"https://openalex.org/keywords/alpha-casein","display_name":"alpha-casein","score":0.9980000257492065},{"id":"https://openalex.org/keywords/beta-sheet-aggregation","display_name":"\u03b2-sheet aggregation","score":0.6610000133514404},{"id":"https://openalex.org/keywords/deuterium-bonding","display_name":"deuterium bonding","score":0.6629999876022339},{"id":"https://openalex.org/keywords/amide-i-band","display_name":"amide I band","score":0.8320000171661377},{"id":"https://openalex.org/keywords/thermal-stability","display_name":"thermal stability","score":0.7239999771118164}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8332074284553528},{"id":"https://openalex.org/C62614982","wikidata":"https://www.wikidata.org/wiki/Q904984","display_name":"Protein secondary structure","level":2,"score":0.79923015832901},{"id":"https://openalex.org/C2778063876","wikidata":"https://www.wikidata.org/wiki/Q192642","display_name":"Myoglobin","level":2,"score":0.7701600790023804},{"id":"https://openalex.org/C2778439535","wikidata":"https://www.wikidata.org/wiki/Q188777","display_name":"Amide","level":2,"score":0.6437512636184692},{"id":"https://openalex.org/C75079739","wikidata":"https://www.wikidata.org/wiki/Q1571801","display_name":"Intramolecular force","level":2,"score":0.6111999750137329},{"id":"https://openalex.org/C2775884256","wikidata":"https://www.wikidata.org/wiki/Q5265080","display_name":"Destabilisation","level":2,"score":0.5870417356491089},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.539249062538147},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.4988420009613037},{"id":"https://openalex.org/C166950319","wikidata":"https://www.wikidata.org/wiki/Q245031","display_name":"Intermolecular force","level":3,"score":0.4648849666118622},{"id":"https://openalex.org/C31684184","wikidata":"https://www.wikidata.org/wiki/Q33293","display_name":"Peptide bond","level":3,"score":0.4319272041320801},{"id":"https://openalex.org/C153642686","wikidata":"https://www.wikidata.org/wiki/Q70906","display_name":"Infrared spectroscopy","level":2,"score":0.41895389556884766},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3336995542049408},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.20218154788017273},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.15578126907348633},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13561159372329712},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D004121","descriptor_name":"Dimethyl Sulfoxide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005583","descriptor_name":"Fourier Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013055","descriptor_name":"Spectrophotometry, Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/0167-4838(91)90563-f","doi":"https://doi.org/10.1016/0167-4838(91)90563-f","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0167-4838(91)90563-f","pdf_url":null,"source":{"id":"https://openalex.org/S4394735818","display_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","issn_l":"0167-4838","issn":["0167-4838","1879-2588"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","raw_type":"journal-article"},{"id":"pmid:2065090","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2065090","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"},{"id":"pmh:oai:cisti-icist.nrc-cnrc.ca:cistinparc:23001178","doi":null,"is_oa":false,"landing_page_url":"https://nrc-publications.canada.ca/eng/view/object/?id=04bea6cf-4f13-4c0f-8e76-80256c033b18","pdf_url":null,"source":{"id":"https://openalex.org/S7407055245","display_name":"NPARC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1969239196","https://openalex.org/W1982188243","https://openalex.org/W1986767985","https://openalex.org/W2005511857","https://openalex.org/W2025494960","https://openalex.org/W2026559340","https://openalex.org/W2029852745","https://openalex.org/W2062102053","https://openalex.org/W2062899668","https://openalex.org/W2064787199","https://openalex.org/W2068388432","https://openalex.org/W2069510735","https://openalex.org/W2072965620","https://openalex.org/W2083818776","https://openalex.org/W2090413444","https://openalex.org/W2103023176"],"related_works":["https://openalex.org/W2019395373","https://openalex.org/W1985647949","https://openalex.org/W2082366117","https://openalex.org/W2901546843","https://openalex.org/W2976851712","https://openalex.org/W2745131378","https://openalex.org/W2002701905","https://openalex.org/W4415432821","https://openalex.org/W2072398888","https://openalex.org/W2136227043"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-15T12:55:33.944570","created_date":"2016-06-24T00:00:00"}