{"id":"https://openalex.org/W1978964554","doi":"https://doi.org/10.4161/hv.27051","title":"Immunogenicity and safety of a CRM-conjugated meningococcal ACWY vaccine administered concomitantly with routine vaccines starting at 2 months of age","display_name":"Immunogenicity and safety of a CRM-conjugated meningococcal ACWY vaccine administered concomitantly with routine vaccines starting at 2 months of age","publication_year":2013,"publication_date":"2013-11-12","ids":{"openalex":"https://openalex.org/W1978964554","doi":"https://doi.org/10.4161/hv.27051","mag":"1978964554","pmid":"https://pubmed.ncbi.nlm.nih.gov/24220326","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4185919"},"language":"en","primary_location":{"id":"doi:10.4161/hv.27051","doi":"https://doi.org/10.4161/hv.27051","is_oa":true,"landing_page_url":"https://doi.org/10.4161/hv.27051","pdf_url":"https://www.tandfonline.com/doi/pdf/10.4161/hv.27051?needAccess=true&role=button","source":{"id":"https://openalex.org/S2483136528","display_name":"Human Vaccines & Immunotherapeutics","issn_l":"2164-5515","issn":["2164-5515","2164-554X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Vaccines & Immunotherapeutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.4161/hv.27051?needAccess=true&role=button","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038228333","display_name":"Terry M. Nolan","orcid":"https://orcid.org/0000-0001-6018-3863","observed_orcids":["https://orcid.org/0000-0001-6018-3863"]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Terry M Nolan","raw_affiliation_strings":["Vaccine and Immunisation Research Group (VIRGo); Melbourne School of Population and Global Health; University of Melbourne and Murdoch Children's Research Institute; Melbourne, VIC Australia","Melbourne School of Population and Global Health","Melbourne, VIC Australia","University of Melbourne and Murdoch Children's Research Institute","Vaccine and Immunisation Research Group (VIRGo)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vaccine and Immunisation Research Group (VIRGo); Melbourne School of Population and Global Health; University of Melbourne and Murdoch Children's Research Institute; Melbourne, VIC Australia","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Melbourne School of Population and Global Health","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Melbourne, VIC Australia","institution_ids":[]},{"raw_affiliation_string":"University of Melbourne and Murdoch Children's Research Institute","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Vaccine and Immunisation Research Group (VIRGo)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006994900","display_name":"Michael D. Nissen","orcid":"https://orcid.org/0000-0003-1686-3313","observed_orcids":["https://orcid.org/0000-0003-1686-3313","https://orcid.org/0000-0001-5279-9174"]},"institutions":[{"id":"https://openalex.org/I1321649718","display_name":"Royal Children's Hospital","ror":"https://ror.org/02rktxt32","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1321649718"]},{"id":"https://openalex.org/I4210121854","display_name":"Queensland Children\u2019s Medical Research Institute","ror":"https://ror.org/02xa7j758","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210121854"]},{"id":"https://openalex.org/I4210167058","display_name":"Children's Health Queensland Hospital and Health Service","ror":"https://ror.org/02t3p7e85","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2801244131","https://openalex.org/I4210167058"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Michael D Nissen","raw_affiliation_strings":["Queensland Paediatric Infectious Diseases Laboratory; Queensland Children's Medical Research Institute, Royal Children's Hospital; Brisbane, QLD Australia","Brisbane, QLD Australia","Queensland Children's Medical Research Institute, Royal Children's Hospital","Queensland Paediatric Infectious Diseases Laboratory"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Queensland Paediatric Infectious Diseases Laboratory; Queensland Children's Medical Research Institute, Royal Children's Hospital; Brisbane, QLD Australia","institution_ids":["https://openalex.org/I4210121854","https://openalex.org/I4210167058"]},{"raw_affiliation_string":"Brisbane, QLD Australia","institution_ids":[]},{"raw_affiliation_string":"Queensland Children's Medical Research Institute, Royal Children's Hospital","institution_ids":["https://openalex.org/I1321649718","https://openalex.org/I4210121854"]},{"raw_affiliation_string":"Queensland Paediatric Infectious Diseases Laboratory","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076555723","display_name":"Aftab Naz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153201","display_name":"Medford Radiology Group","ror":"https://ror.org/04n9jx253","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210153201"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aftab Naz","raw_affiliation_strings":["Madera Family Medical Group; Madera, CA USA","Madera Family Medical Group","Madera, CA USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Madera Family Medical Group; Madera, CA USA","institution_ids":["https://openalex.org/I4210153201"]},{"raw_affiliation_string":"Madera Family Medical Group","institution_ids":[]},{"raw_affiliation_string":"Madera, CA USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044171590","display_name":"Julie S. Shepard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118678","display_name":"Ohio Pediatric Research Association","ror":"https://ror.org/02pndtz33","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210118678"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julie Shepard","raw_affiliation_strings":["Ohio Pediatric Research Association; Vandalia, OH USA","Ohio Pediatric Research Association","Vandalia, OH USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ohio Pediatric Research Association; Vandalia, OH USA","institution_ids":["https://openalex.org/I4210118678"]},{"raw_affiliation_string":"Ohio Pediatric Research Association","institution_ids":["https://openalex.org/I4210118678"]},{"raw_affiliation_string":"Vandalia, OH USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006842946","display_name":"Lisa Bedell","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lisa Bedell","raw_affiliation_strings":["Novartis Vaccines and Diagnostics; Cambridge, MA USA","Cambridge, MA USA","Novartis Vaccines and Diagnostics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Vaccines and Diagnostics; Cambridge, MA USA","institution_ids":[]},{"raw_affiliation_string":"Cambridge, MA USA","institution_ids":[]},{"raw_affiliation_string":"Novartis Vaccines and Diagnostics","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109915296","display_name":"Matthew J. Hohenboken","orcid":"https://orcid.org/0000-0003-0453-1418","observed_orcids":["https://orcid.org/0000-0003-0453-1418"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthew Hohenboken","raw_affiliation_strings":["Novartis Vaccines and Diagnostics; Cambridge, MA USA","Cambridge, MA USA","Novartis Vaccines and Diagnostics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Vaccines and Diagnostics; Cambridge, MA USA","institution_ids":[]},{"raw_affiliation_string":"Cambridge, MA USA","institution_ids":[]},{"raw_affiliation_string":"Novartis Vaccines and Diagnostics","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113587863","display_name":"Tatjana M. Odrljin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tatjana Odrljin","raw_affiliation_strings":["Novartis Vaccines and Diagnostics; Cambridge, MA USA","Cambridge, MA USA","Novartis Vaccines and Diagnostics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Vaccines and Diagnostics; Cambridge, MA USA","institution_ids":[]},{"raw_affiliation_string":"Cambridge, MA USA","institution_ids":[]},{"raw_affiliation_string":"Novartis Vaccines and Diagnostics","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000830489","display_name":"Peter M Dull","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter M Dull","raw_affiliation_strings":["Novartis Vaccines and Diagnostics; Cambridge, MA USA","Cambridge, MA USA","Novartis Vaccines and Diagnostics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Vaccines and Diagnostics; Cambridge, MA USA","institution_ids":[]},{"raw_affiliation_string":"Cambridge, MA USA","institution_ids":[]},{"raw_affiliation_string":"Novartis Vaccines and Diagnostics","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5038228333"],"corresponding_institution_ids":["https://openalex.org/I165779595","https://openalex.org/I4210150290"],"apc_list":{"value":2895,"currency":"EUR","value_usd":3175},"apc_paid":null,"fwci":2.7422,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.883314,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"10","issue":"2","first_page":"280","last_page":"289"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/menacwy-crm","display_name":"MenACWY-CRM","score":0.9330000281333923},{"id":"https://openalex.org/keywords/simultaneous-vaccination","display_name":"simultaneous vaccination","score":0.7239999771118164},{"id":"https://openalex.org/keywords/infant-immunization","display_name":"infant immunization","score":0.7239999771118164},{"id":"https://openalex.org/keywords/vaccine-immunogenicity","display_name":"vaccine immunogenicity","score":0.7940000295639038},{"id":"https://openalex.org/keywords/vaccine-safety","display_name":"vaccine safety","score":0.9729999899864197},{"id":"https://openalex.org/keywords/reactogenicity","display_name":"reactogenicity","score":0.8659999966621399},{"id":"https://openalex.org/keywords/serum-bactericidal-assay","display_name":"serum bactericidal assay","score":0.6930000185966492},{"id":"https://openalex.org/keywords/pneumococcal-conjugate-vaccine","display_name":"pneumococcal conjugate vaccine","score":0.7720000147819519},{"id":"https://openalex.org/keywords/hepatitis-b-vaccine","display_name":"hepatitis B vaccine","score":0.9150000214576721},{"id":"https://openalex.org/keywords/mmr-vaccine","display_name":"MMR vaccine","score":0.8669999837875366},{"id":"https://openalex.org/keywords/non-inferiority","display_name":"non-inferiority","score":0.7149999737739563},{"id":"https://openalex.org/keywords/meningococcal-disease-prevention","display_name":"meningococcal disease prevention","score":0.7760000228881836}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8874858617782593},{"id":"https://openalex.org/C2777704310","wikidata":"https://www.wikidata.org/wiki/Q7300322","display_name":"Reactogenicity","level":4,"score":0.870974063873291},{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.6823377013206482},{"id":"https://openalex.org/C2779841045","wikidata":"https://www.wikidata.org/wiki/Q47790","display_name":"Tetanus","level":3,"score":0.6706643104553223},{"id":"https://openalex.org/C2780572238","wikidata":"https://www.wikidata.org/wiki/Q134649","display_name":"Diphtheria","level":3,"score":0.6465467214584351},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.6299117803573608},{"id":"https://openalex.org/C2780454893","wikidata":"https://www.wikidata.org/wiki/Q6817090","display_name":"Meningococcal vaccine","level":4,"score":0.5454866886138916},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4603206515312195},{"id":"https://openalex.org/C2776438120","wikidata":"https://www.wikidata.org/wiki/Q79793","display_name":"Measles","level":3,"score":0.4424915909767151},{"id":"https://openalex.org/C2779631682","wikidata":"https://www.wikidata.org/wiki/Q12438936","display_name":"Poliovirus","level":3,"score":0.43883875012397766},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4361709952354431},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.42945975065231323},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.42930155992507935},{"id":"https://openalex.org/C2779583294","wikidata":"https://www.wikidata.org/wiki/Q5161160","display_name":"Conjugate vaccine","level":4,"score":0.4128507673740387},{"id":"https://openalex.org/C2780801004","wikidata":"https://www.wikidata.org/wiki/Q1415366","display_name":"Immunization","level":3,"score":0.3985527455806732},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23544076085090637},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.20693805813789368},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.08775031566619873},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069443","descriptor_name":"Heptavalent Pneumococcal Conjugate Vaccine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007115","descriptor_name":"Immunization Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011054","descriptor_name":"Poliovirus Vaccine, Inactivated","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014611","descriptor_name":"Vaccination","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015721","descriptor_name":"Diphtheria-Tetanus-Pertussis Vaccine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017325","descriptor_name":"Hepatitis B Vaccines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D017325","descriptor_name":"Hepatitis B Vaccines","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D017325","descriptor_name":"Hepatitis B Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018073","descriptor_name":"Haemophilus Vaccines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D018074","descriptor_name":"Vaccines, Conjugate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D022242","descriptor_name":"Pneumococcal Vaccines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D022242","descriptor_name":"Pneumococcal Vaccines","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D022242","descriptor_name":"Pneumococcal Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D022401","descriptor_name":"Meningococcal Vaccines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D022401","descriptor_name":"Meningococcal Vaccines","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D022401","descriptor_name":"Meningococcal Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D022542","descriptor_name":"Measles-Mumps-Rubella Vaccine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D022542","descriptor_name":"Measles-Mumps-Rubella Vaccine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D022542","descriptor_name":"Measles-Mumps-Rubella Vaccine","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.4161/hv.27051","doi":"https://doi.org/10.4161/hv.27051","is_oa":true,"landing_page_url":"https://doi.org/10.4161/hv.27051","pdf_url":"https://www.tandfonline.com/doi/pdf/10.4161/hv.27051?needAccess=true&role=button","source":{"id":"https://openalex.org/S2483136528","display_name":"Human Vaccines & Immunotherapeutics","issn_l":"2164-5515","issn":["2164-5515","2164-554X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Vaccines & Immunotherapeutics","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3305553","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4185919","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:24220326","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24220326","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human vaccines & immunotherapeutics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4185919","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4185919/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hum Vaccin Immunother","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.4161/hv.27051","doi":"https://doi.org/10.4161/hv.27051","is_oa":true,"landing_page_url":"https://doi.org/10.4161/hv.27051","pdf_url":"https://www.tandfonline.com/doi/pdf/10.4161/hv.27051?needAccess=true&role=button","source":{"id":"https://openalex.org/S2483136528","display_name":"Human Vaccines & Immunotherapeutics","issn_l":"2164-5515","issn":["2164-5515","2164-554X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Vaccines & Immunotherapeutics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310932","display_name":"University of Victoria","ror":"https://ror.org/04s5mat29"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1978964554.pdf","grobid_xml":"https://content.openalex.org/works/W1978964554.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1933668405","https://openalex.org/W1976881351","https://openalex.org/W1978153776","https://openalex.org/W1984338589","https://openalex.org/W1992226822","https://openalex.org/W2007743882","https://openalex.org/W2010942366","https://openalex.org/W2011114820","https://openalex.org/W2011918489","https://openalex.org/W2013244135","https://openalex.org/W2013735067","https://openalex.org/W2014143082","https://openalex.org/W2016357226","https://openalex.org/W2029328852","https://openalex.org/W2046127942","https://openalex.org/W2046816328","https://openalex.org/W2050438856","https://openalex.org/W2056663174","https://openalex.org/W2067415595","https://openalex.org/W2068368401","https://openalex.org/W2076368266","https://openalex.org/W2078107959","https://openalex.org/W2080619688","https://openalex.org/W2086965801","https://openalex.org/W2091356778","https://openalex.org/W2109381880","https://openalex.org/W2120356293","https://openalex.org/W2123656964","https://openalex.org/W2125460037","https://openalex.org/W2133410828","https://openalex.org/W2148502123","https://openalex.org/W2160879811","https://openalex.org/W2161309656","https://openalex.org/W2171890935","https://openalex.org/W2333584948","https://openalex.org/W4244229764","https://openalex.org/W4249066710","https://openalex.org/W4411164182"],"related_works":["https://openalex.org/W2039889964","https://openalex.org/W2029328852","https://openalex.org/W2011918489","https://openalex.org/W2067415595","https://openalex.org/W2046127942","https://openalex.org/W1975710912","https://openalex.org/W2011114820","https://openalex.org/W1777714051","https://openalex.org/W2046816328","https://openalex.org/W2426807888"],"abstract_inverted_index":{"BACKGROUND:":[0],"Infants":[1],"are":[2],"at":[3,39],"the":[4,27,112,144,183,189,248],"highest":[5],"risk":[6],"for":[7,141],"meningococcal":[8],"disease":[9],"and":[10,14,29,43,70,73,90,99,123,175,239],"a":[11,32],"broadly":[12],"protective":[13],"safe":[15],"vaccine":[16,57,61,68,75,121],"is":[17],"an":[18],"unmet":[19],"need":[20],"in":[21,86,107,169],"this":[22],"youngest":[23],"population.":[24],"We":[25],"evaluated":[26],"immunogenicity":[28],"safety":[30],"of":[31,36,46,80,92,109,182],"4-dose":[33],"infant/toddler":[34],"regimen":[35],"MenACWY-CRM":[37,81,133,155,163,206],"given":[38],"2,":[40],"4,":[41],"6,":[42],"12":[44],"months":[45],"age":[47],"concomitantly":[48,158],"with":[49,132,159,165,188,207],"pentavalent":[50],"diphtheria-tetanus-acellular":[51],"pertussis-Hemophilus":[52],"influenzae":[53],"type":[54],"b-inactivated":[55],"poliovirus-combination":[56],"(DTaP-IPV/Hib),":[58],"hepatitis":[59],"B":[60],"(HBV),":[62],"7-":[63],"or":[64,213],"13-valent":[65],"conjugate":[66],"pneumococcal":[67],"(PCV),":[69],"measles,":[71],"mumps,":[72],"rubella":[74],"(MMR).":[76],"RESULTS:":[77],"Four":[78],"doses":[79],"induced":[82,176],"hSBA":[83,102],"titers":[84,103],"\u22658":[85,104],"89%,":[87],"95%,":[88],"97%,":[89],"96%":[91],"participants":[93,110],"against":[94,180],"serogroups":[95,184],"A,":[96],"C,":[97],"W-135,":[98],"Y,":[100],"respectively.":[101],"were":[105,134,202,245],"present":[106],"76-98%":[108],"after":[111],"first":[113],"3":[114],"doses.":[115],"A":[116],"categorical":[117],"linear":[118],"analysis":[119],"incorporating":[120],"group":[122],"study":[124,243,249],"center":[125],"showed":[126],"responses":[127,179,191],"to":[128,136,143,192,204,242],"routine":[129,137,160,166,193,208,214],"vaccines":[130,138,209,215],"administered":[131,157,164],"non-inferior":[135],"alone,":[139],"except":[140],"seroresponse":[142],"pertussis":[145],"antigen":[146],"fimbriae.":[147],"The":[148],"reactogenicity":[149],"profile":[150],"was":[151,156,172,221],"not":[152],"affected":[153],"when":[154],"vaccines.":[161],"CONCLUSION:":[162],"concomitant":[167],"vaccinations":[168],"young":[170],"infants":[171,201],"well":[173],"tolerated":[174],"highly":[177],"immunogenic":[178],"each":[181],"without":[185],"significant":[186],"interference":[187],"immune":[190],"infant":[194],"vaccinations.":[195],"METHODS:":[196],"Healthy":[197],"2":[198],"month":[199],"old":[200],"randomized":[203],"receive":[205],"(n":[210,217],"=":[211,218],"258)":[212],"alone":[216],"271).":[219],"Immunogenicity":[220],"assessed":[222],"by":[223],"serum":[224],"bactericidal":[225],"assay":[226],"using":[227],"human":[228],"complement":[229],"(hSBA).":[230],"Medically":[231],"attended":[232],"adverse":[233],"events":[234],"(AEs),":[235],"serious":[236],"AEs":[237,240],"(SAEs)":[238],"leading":[241],"withdrawal":[244],"collected":[246],"throughout":[247],"period.":[250]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}