{"id":"https://openalex.org/W1978924924","doi":"https://doi.org/10.1007/s00125-010-1835-4","title":"Lineage tracing and resulting phenotype of haemopoietic-derived cells in the pancreas during beta cell regeneration","display_name":"Lineage tracing and resulting phenotype of haemopoietic-derived cells in the pancreas during beta cell regeneration","publication_year":2010,"publication_date":"2010-06-28","ids":{"openalex":"https://openalex.org/W1978924924","doi":"https://doi.org/10.1007/s00125-010-1835-4","mag":"1978924924","pmid":"https://pubmed.ncbi.nlm.nih.gov/20585934"},"language":"en","primary_location":{"id":"doi:10.1007/s00125-010-1835-4","doi":"https://doi.org/10.1007/s00125-010-1835-4","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00125-010-1835-4","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00125-010-1835-4.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1007/s00125-010-1835-4.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045264466","display_name":"Astrid Chamson-Reig","orcid":"https://orcid.org/0000-0002-1107-473X","observed_orcids":["https://orcid.org/0000-0002-1107-473X"]},"institutions":[{"id":"https://openalex.org/I131944076","display_name":"Lawson Health Research Institute","ror":"https://ror.org/051gsh239","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I131944076"]},{"id":"https://openalex.org/I4210151658","display_name":"St Joseph's Health Care","ror":"https://ror.org/05rj7xr73","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210151658"]},{"id":"https://openalex.org/I4405255220","display_name":"Lawson Research Institute","ror":"https://ror.org/02rkgge26","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210151658","https://openalex.org/I4405255220"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"A. Chamson-Reig","raw_affiliation_strings":["Lawson Health Research Institute, St Joseph's Health Care, 268 Grosvenor Street, London, ON, Canada N6A 4V2","Lawson Health Research Institute, St Joseph\u2019s Health Care"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lawson Health Research Institute, St Joseph's Health Care, 268 Grosvenor Street, London, ON, Canada N6A 4V2","institution_ids":["https://openalex.org/I131944076","https://openalex.org/I4210151658","https://openalex.org/I4405255220"]},{"raw_affiliation_string":"Lawson Health Research Institute, St Joseph\u2019s Health Care","institution_ids":["https://openalex.org/I131944076","https://openalex.org/I4210151658"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000343189","display_name":"Edith Juliana Arany","orcid":"https://orcid.org/0000-0001-9994-8958","observed_orcids":["https://orcid.org/0000-0001-9994-8958"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I131944076","display_name":"Lawson Health Research Institute","ror":"https://ror.org/051gsh239","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I131944076"]},{"id":"https://openalex.org/I4210151658","display_name":"St Joseph's Health Care","ror":"https://ror.org/05rj7xr73","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210151658"]},{"id":"https://openalex.org/I4405255220","display_name":"Lawson Research Institute","ror":"https://ror.org/02rkgge26","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210151658","https://openalex.org/I4405255220"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"E. J. Arany","raw_affiliation_strings":["Department of Medicine, The University of Western Ontario, London, ON, Canada","Department of Pathology, The University of Western Ontario, London, ON, Canada","Lawson Health Research Institute, St Joseph\u2019s Health Care, 268 Grosvenor Street, London, ON, Canada, N6A 4V2","Lawson Health Research Institute, St Joseph\u2019s Health Care","The University of Western Ontario"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, The University of Western Ontario, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Department of Pathology, The University of Western Ontario, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Lawson Health Research Institute, St Joseph\u2019s Health Care, 268 Grosvenor Street, London, ON, Canada, N6A 4V2","institution_ids":["https://openalex.org/I131944076","https://openalex.org/I4210151658","https://openalex.org/I4405255220"]},{"raw_affiliation_string":"Lawson Health Research Institute, St Joseph\u2019s Health Care","institution_ids":["https://openalex.org/I131944076","https://openalex.org/I4210151658"]},{"raw_affiliation_string":"The University of Western Ontario","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034429380","display_name":"David J. Hill","orcid":"https://orcid.org/0000-0002-2490-5678","observed_orcids":["https://orcid.org/0000-0002-2490-5678"]},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]},{"id":"https://openalex.org/I131944076","display_name":"Lawson Health Research Institute","ror":"https://ror.org/051gsh239","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I131944076"]},{"id":"https://openalex.org/I4210151658","display_name":"St Joseph's Health Care","ror":"https://ror.org/05rj7xr73","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210151658"]},{"id":"https://openalex.org/I4405255220","display_name":"Lawson Research Institute","ror":"https://ror.org/02rkgge26","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210151658","https://openalex.org/I4405255220"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"D. J. Hill","raw_affiliation_strings":["Department of Medicine, The University of Western Ontario, London, ON, Canada","Department of Paediatrics, The University of Western Ontario, London, ON, Canada","Department of Physiology and Pharmacology, The University of Western Ontario, London, ON, Canada","Lawson Health Research Institute, St Joseph\u2019s Health Care, 268 Grosvenor Street, London, ON, Canada, N6A 4V2","Lawson Health Research Institute, St Joseph\u2019s Health Care","The University of Western Ontario"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, The University of Western Ontario, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Department of Paediatrics, The University of Western Ontario, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Department of Physiology and Pharmacology, The University of Western Ontario, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Lawson Health Research Institute, St Joseph\u2019s Health Care, 268 Grosvenor Street, London, ON, Canada, N6A 4V2","institution_ids":["https://openalex.org/I131944076","https://openalex.org/I4210151658","https://openalex.org/I4405255220"]},{"raw_affiliation_string":"Lawson Health Research Institute, St Joseph\u2019s Health Care","institution_ids":["https://openalex.org/I131944076","https://openalex.org/I4210151658"]},{"raw_affiliation_string":"The University of Western Ontario","institution_ids":["https://openalex.org/I125749732"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5034429380"],"corresponding_institution_ids":["https://openalex.org/I125749732","https://openalex.org/I131944076","https://openalex.org/I4210151658","https://openalex.org/I4405255220"],"apc_list":{"value":3490,"currency":"USD","value_usd":3490},"apc_paid":null,"fwci":3.3729,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.91100488,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"53","issue":"10","first_page":"2188","last_page":"2197"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/beta-cell-regeneration","display_name":"beta cell regeneration","score":0.9290000200271606},{"id":"https://openalex.org/keywords/beta-cell-destruction","display_name":"beta cell destruction","score":0.6050000190734863},{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.8539999723434448},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.7850000262260437},{"id":"https://openalex.org/keywords/insulitis","display_name":"insulitis","score":0.3889999985694885},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.7099999785423279},{"id":"https://openalex.org/keywords/pdx1","display_name":"PDX1","score":0.8080000281333923},{"id":"https://openalex.org/keywords/bone-marrow-derived-cells","display_name":"bone marrow-derived cells","score":0.6129999756813049}],"concepts":[{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.7013548016548157},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.6503332257270813},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.6342741250991821},{"id":"https://openalex.org/C2776174256","wikidata":"https://www.wikidata.org/wiki/Q830842","display_name":"BETA (programming language)","level":2,"score":0.6146773099899292},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5814592838287354},{"id":"https://openalex.org/C2776828364","wikidata":"https://www.wikidata.org/wiki/Q1767180","display_name":"Beta cell","level":4,"score":0.5559831261634827},{"id":"https://openalex.org/C2776817793","wikidata":"https://www.wikidata.org/wiki/Q6553369","display_name":"Lineage (genetic)","level":3,"score":0.5449212789535522},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.440871000289917},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.34948182106018066},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29272598028182983},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24645984172821045},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.19647714495658875},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.09422913193702698},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C165220095","wikidata":"https://www.wikidata.org/wiki/Q207524","display_name":"Islet","level":3,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003921","descriptor_name":"Diabetes Mellitus, Experimental","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012038","descriptor_name":"Regeneration","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018380","descriptor_name":"Hematopoietic Stem Cell Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D050417","descriptor_name":"Insulin-Secreting Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s00125-010-1835-4","doi":"https://doi.org/10.1007/s00125-010-1835-4","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00125-010-1835-4","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00125-010-1835-4.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},{"id":"pmid:20585934","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20585934","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"Journal Article"},{"id":"pmh:oai:ir.lib.uwo.ca:paedpub-1685","doi":null,"is_oa":false,"landing_page_url":"https://ir.lib.uwo.ca/paedpub/677","pdf_url":null,"source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Paediatrics Publications","raw_type":"article"},{"id":"pmh:oai:uwo.scholaris.ca:20.500.14721/24549","doi":null,"is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00125-010-1835-4","pdf_url":null,"source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.1007/s00125-010-1835-4","doi":"https://doi.org/10.1007/s00125-010-1835-4","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00125-010-1835-4","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00125-010-1835-4.pdf","source":{"id":"https://openalex.org/S104375418","display_name":"Diabetologia","issn_l":"0012-186X","issn":["0012-186X","1432-0428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetologia","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9789000153541565,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1978924924.pdf","grobid_xml":"https://content.openalex.org/works/W1978924924.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1970417260","https://openalex.org/W1976221714","https://openalex.org/W1984296228","https://openalex.org/W1993328941","https://openalex.org/W1993902386","https://openalex.org/W2002817805","https://openalex.org/W2004140559","https://openalex.org/W2010510062","https://openalex.org/W2013592169","https://openalex.org/W2014715897","https://openalex.org/W2020962857","https://openalex.org/W2024313361","https://openalex.org/W2024952102","https://openalex.org/W2040158161","https://openalex.org/W2048917856","https://openalex.org/W2063294193","https://openalex.org/W2071557003","https://openalex.org/W2074291164","https://openalex.org/W2081829424","https://openalex.org/W2096091265","https://openalex.org/W2107471483","https://openalex.org/W2115936490","https://openalex.org/W2117481455","https://openalex.org/W2117547652","https://openalex.org/W2126792448","https://openalex.org/W2128145658","https://openalex.org/W2137140254","https://openalex.org/W2139707983","https://openalex.org/W2145196276","https://openalex.org/W2150971678","https://openalex.org/W2156244085","https://openalex.org/W2158141897","https://openalex.org/W2166454482","https://openalex.org/W2167520347","https://openalex.org/W2169870204"],"related_works":["https://openalex.org/W2316201828","https://openalex.org/W1981946124","https://openalex.org/W2083023652","https://openalex.org/W2167520347","https://openalex.org/W2040158161","https://openalex.org/W1486553854","https://openalex.org/W1995489142","https://openalex.org/W2035401342","https://openalex.org/W1976221714","https://openalex.org/W2031414639"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}