{"id":"https://openalex.org/W1978892978","doi":"https://doi.org/10.1021/es1042673","title":"Cellular and Transcriptional Response of Pseudomonas stutzeri to Quantum Dots under Aerobic and Denitrifying Conditions","display_name":"Cellular and Transcriptional Response of Pseudomonas stutzeri to Quantum Dots under Aerobic and Denitrifying Conditions","publication_year":2011,"publication_date":"2011-04-28","ids":{"openalex":"https://openalex.org/W1978892978","doi":"https://doi.org/10.1021/es1042673","mag":"1978892978","pmid":"https://pubmed.ncbi.nlm.nih.gov/21526814"},"language":"en","primary_location":{"id":"doi:10.1021/es1042673","doi":"https://doi.org/10.1021/es1042673","is_oa":false,"landing_page_url":"https://doi.org/10.1021/es1042673","pdf_url":null,"source":{"id":"https://openalex.org/S13479253","display_name":"Environmental Science & Technology","issn_l":"0013-936X","issn":["0013-936X","1520-5851"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","fnege-4","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Science & Technology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101589944","display_name":"Yu Yang","orcid":"https://orcid.org/0000-0002-2112-7014","observed_orcids":["https://orcid.org/0000-0002-2112-7014"]},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yu Yang","raw_affiliation_strings":["Department of Civil and Environmental Engineering, Rice University, Houston, Texas 77005, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Civil and Environmental Engineering, Rice University, Houston, Texas 77005, United States","institution_ids":["https://openalex.org/I74775410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029337769","display_name":"Huiguang Zhu","orcid":"https://orcid.org/0000-0001-7051-9463","observed_orcids":["https://orcid.org/0000-0001-7051-9463"]},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huiguang Zhu","raw_affiliation_strings":["Department of Chemistry, Rice University, Houston, Texas 77005, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Rice University, Houston, Texas 77005, United States","institution_ids":["https://openalex.org/I74775410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001140872","display_name":"Vicki L. Colvin","orcid":"https://orcid.org/0000-0002-8526-515X","observed_orcids":["https://orcid.org/0000-0002-8526-515X"]},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vicki L. Colvin","raw_affiliation_strings":["Department of Chemistry, Rice University, Houston, Texas 77005, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Rice University, Houston, Texas 77005, United States","institution_ids":["https://openalex.org/I74775410"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081251356","display_name":"Pedro J. J. Alvarez","orcid":"https://orcid.org/0000-0002-6725-7199","observed_orcids":["https://orcid.org/0000-0002-6725-7199"]},"institutions":[{"id":"https://openalex.org/I74775410","display_name":"Rice University","ror":"https://ror.org/008zs3103","country_code":"US","type":"education","lineage":["https://openalex.org/I74775410"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Pedro J. Alvarez","raw_affiliation_strings":["Department of Civil and Environmental Engineering, Rice University, Houston, Texas 77005, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Civil and Environmental Engineering, Rice University, Houston, Texas 77005, United States","institution_ids":["https://openalex.org/I74775410"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5081251356"],"corresponding_institution_ids":["https://openalex.org/I74775410"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":3.084,"has_fulltext":false,"cited_by_count":62,"citation_normalized_percentile":{"value":0.92296755,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"45","issue":"11","first_page":"4988","last_page":"4994"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.6226000189781189,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.6226000189781189,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10419","display_name":"Pharmaceutical and Antibiotic Environmental Impacts","score":0.09139999747276306,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10564","display_name":"Wastewater Treatment and Nitrogen Removal","score":0.052799999713897705,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/quantum-dots","display_name":"quantum dots","score":0.9079999923706055},{"id":"https://openalex.org/keywords/pseudomonas-stutzeri","display_name":"Pseudomonas stutzeri","score":0.9980000257492065},{"id":"https://openalex.org/keywords/denitrification","display_name":"denitrification","score":0.8730000257492065},{"id":"https://openalex.org/keywords/polyethylenimine-coating","display_name":"polyethyleneimine coating","score":0.7580000162124634},{"id":"https://openalex.org/keywords/membrane-potential","display_name":"membrane potential","score":0.6340000033378601},{"id":"https://openalex.org/keywords/energy-transduction","display_name":"energy transduction","score":0.7580000162124634},{"id":"https://openalex.org/keywords/nitrate-reductase","display_name":"nitrate reductase","score":0.7009999752044678},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.7149999737739563},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.828000009059906},{"id":"https://openalex.org/keywords/efflux-pump-genes","display_name":"efflux pump genes","score":0.746999979019165},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C197011783","wikidata":"https://www.wikidata.org/wiki/Q5257859","display_name":"Denitrifying bacteria","level":4,"score":0.8498114347457886},{"id":"https://openalex.org/C2776786877","wikidata":"https://www.wikidata.org/wiki/Q2888828","display_name":"Pseudomonas stutzeri","level":3,"score":0.7866170406341553},{"id":"https://openalex.org/C2778710519","wikidata":"https://www.wikidata.org/wiki/Q420896","display_name":"Nitrate reductase","level":3,"score":0.7362982034683228},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.639557957649231},{"id":"https://openalex.org/C73593433","wikidata":"https://www.wikidata.org/wiki/Q742637","display_name":"Denitrification","level":3,"score":0.5819895267486572},{"id":"https://openalex.org/C2781341435","wikidata":"https://www.wikidata.org/wiki/Q409788","display_name":"Nitrite reductase","level":4,"score":0.5716911554336548},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.48485979437828064},{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.4298554062843323},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.3746896982192993},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3658730089664459},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.22983098030090332},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21638193726539612},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.1598232090473175},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.09095177054405212},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08665671944618225},{"id":"https://openalex.org/C537208039","wikidata":"https://www.wikidata.org/wiki/Q627","display_name":"Nitrogen","level":2,"score":0.07099252939224243},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000332","descriptor_name":"Aerobiosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000693","descriptor_name":"Anaerobiosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008564","descriptor_name":"Membrane Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019216","descriptor_name":"Metals, Heavy","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D044223","descriptor_name":"Pseudomonas stutzeri","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D044223","descriptor_name":"Pseudomonas stutzeri","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D044223","descriptor_name":"Pseudomonas stutzeri","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045663","descriptor_name":"Quantum Dots","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058440","descriptor_name":"Denitrification","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1021/es1042673","doi":"https://doi.org/10.1021/es1042673","is_oa":false,"landing_page_url":"https://doi.org/10.1021/es1042673","pdf_url":null,"source":{"id":"https://openalex.org/S13479253","display_name":"Environmental Science & Technology","issn_l":"0013-936X","issn":["0013-936X","1520-5851"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","fnege-4","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Science & Technology","raw_type":"journal-article"},{"id":"pmid:21526814","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21526814","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental science & technology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.469.5686","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.469.5686","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://alvarez.blogs.rice.edu/files/2012/02/136.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6618000268936157,"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1951583206","https://openalex.org/W1967176839","https://openalex.org/W1972605174","https://openalex.org/W1977465667","https://openalex.org/W1978883528","https://openalex.org/W1981399011","https://openalex.org/W1985117590","https://openalex.org/W1985709364","https://openalex.org/W1988494823","https://openalex.org/W1993225828","https://openalex.org/W2004107049","https://openalex.org/W2007266049","https://openalex.org/W2012128752","https://openalex.org/W2016627888","https://openalex.org/W2017870671","https://openalex.org/W2028024021","https://openalex.org/W2029920007","https://openalex.org/W2032519069","https://openalex.org/W2037747044","https://openalex.org/W2039808992","https://openalex.org/W2044971968","https://openalex.org/W2061105842","https://openalex.org/W2062498920","https://openalex.org/W2062898787","https://openalex.org/W2065706045","https://openalex.org/W2070296742","https://openalex.org/W2083066959","https://openalex.org/W2086754387","https://openalex.org/W2087363409","https://openalex.org/W2089860144","https://openalex.org/W2092218613","https://openalex.org/W2106412044","https://openalex.org/W2106955414","https://openalex.org/W2112101570","https://openalex.org/W2114443210","https://openalex.org/W2117326659","https://openalex.org/W2118685639","https://openalex.org/W2122483392","https://openalex.org/W2124622139","https://openalex.org/W2135805035","https://openalex.org/W2139980848","https://openalex.org/W2143535440","https://openalex.org/W2152382917","https://openalex.org/W2160253522","https://openalex.org/W2164845223","https://openalex.org/W2171047154","https://openalex.org/W2183330967","https://openalex.org/W2325971033","https://openalex.org/W2405210256","https://openalex.org/W2425092090"],"related_works":["https://openalex.org/W2156649347","https://openalex.org/W2055881597","https://openalex.org/W7098335975","https://openalex.org/W2029920007","https://openalex.org/W2010788931","https://openalex.org/W2751305364","https://openalex.org/W2117742022","https://openalex.org/W3184401473","https://openalex.org/W2099942677","https://openalex.org/W1967176839"],"abstract_inverted_index":{"Pseudomonas":[0],"stutzeri":[1],"was":[2,59,83,145,183,237],"exposed":[3],"to":[4,41,43,114,187,215,240,252],"quantum":[5],"dots":[6],"(QDs)":[7],"with":[8,54,86,266],"three":[9],"different":[10],"surface":[11],"coatings":[12,192,269],"(anionic":[13],"polymaleic":[14],"anhydride-alt-1-octadecene":[15],"(PMAO),":[16],"cationic":[17],"polyethylenimine":[18],"(PEI),":[19],"and":[20,26,66,80,107,159,172,193,259],"carboxyl":[21,42],"QDs)":[22],"under":[23,89,166,210,227],"both":[24],"aerobic":[25,31,211],"anaerobic":[27],"(denitrifying)":[28],"conditions.":[29,91],"Under":[30],"conditions,":[32,168,212],"toxicity":[33],"(assessed":[34,124],"per":[35,125],"growth":[36],"inhibition)":[37],"increased":[38,134],"from":[39,175],"PMAO":[40,65],"PEI":[44,50,67,87,116,137,152,164,271],"QDs.":[45],"The":[46,223],"positive":[47],"charge":[48],"of":[49,93,132,190,197,201,218,225,235,257,262],"facilitated":[51],"direct":[52],"contact":[53],"negatively":[55],"charged":[56,268],"bacteria,":[57],"which":[58],"verified":[60],"by":[61,73,163],"TEM":[62],"analysis.":[63],"Both":[64],"QDs":[68,88,165,176,236],"hindered":[69,146],"energy":[70],"transduction":[71],"(indicated":[72],"a":[74,255],"decrease":[75],"in":[76,129],"cell":[77,141],"membrane":[78],"potential),":[79],"this":[81,245],"effect":[82],"most":[84],"pronounced":[85],"denitrifying":[90,167,228],"Up-regulation":[92,200],"denitrification":[94,122,253],"genes":[95,157],"(i.e.,":[96],"nitrate":[97,101,127],"reductase":[98,102,105,109],"narG,":[99],"periplasmic":[100],"napB,":[103],"nitrite":[104],"nirH,":[106],"NO":[108],"norB)":[110],"occurred":[111,208],"upon":[112],"exposure":[113],"subinhibitory":[115],"QD":[117,138,153,191],"concentrations":[118],"(1":[119],"nM).":[120],"Accordingly,":[121],"activity":[123,234],"respiratory":[126],"consumption":[128],"the":[130,194,202,232],"presence":[131],"ammonia)":[133],"during":[135],"sublethal":[136],"exposure.":[139],"However,":[140],"viability":[142],"(including":[143],"denitrification)":[144],"at":[147,184],"10":[148],"nM":[149],"or":[150],"higher":[151],"concentrations.":[154],"Efflux":[155],"pump":[156],"czcB":[158],"czcC":[160],"were":[161],"induced":[162],"even":[169],"though":[170],"Cd":[171],"Se":[173],"dissolution":[174],"did":[177],"not":[178,238],"reach":[179],"toxic":[180],"levels":[181],"(exposure":[182],"pH":[185],"7":[186],"minimize":[188],"hydrolysis":[189],"associated":[195],"release":[196],"metal":[198],"constituents).":[199],"superoxide":[203],"dismutase":[204],"(stress)":[205],"gene":[206],"sodB":[207],"only":[209],"likely":[213],"due":[214,239],"intracellular":[216],"production":[217,242],"reactive":[219],"oxygen":[220],"species":[221],"(ROS).":[222],"absence":[224],"ROS":[226,241],"conditions":[229],"suggests":[230],"that":[231],"antibacterial":[233],"alone.":[243],"Overall,":[244],"work":[246],"forewarns":[247],"about":[248],"unintended":[249],"potential":[250],"impacts":[251],"as":[254],"result":[256],"disposal":[258],"incidental":[260],"releases":[261],"QDs,":[263],"especially":[264],"those":[265],"positively":[267],"(e.g.,":[270],"QDs).":[272]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}