{"id":"https://openalex.org/W1978804351","doi":"https://doi.org/10.3390/ijms15046184","title":"Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease","display_name":"Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease","publication_year":2014,"publication_date":"2014-04-11","ids":{"openalex":"https://openalex.org/W1978804351","doi":"https://doi.org/10.3390/ijms15046184","mag":"1978804351","pmid":"https://pubmed.ncbi.nlm.nih.gov/24733068","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4013623"},"language":"en","primary_location":{"id":"doi:10.3390/ijms15046184","doi":"https://doi.org/10.3390/ijms15046184","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms15046184","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/ijms15046184","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009925739","display_name":"Un Ju Jung","orcid":"https://orcid.org/0000-0002-5441-460X","observed_orcids":["https://orcid.org/0000-0002-5441-460X"]},"institutions":[{"id":"https://openalex.org/I31419693","display_name":"Kyungpook National University","ror":"https://ror.org/040c17130","country_code":"KR","type":"education","lineage":["https://openalex.org/I31419693"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Un Jung","raw_affiliation_strings":["Center for Food and Nutritional Genomics Research, Kyungpook National University, 1370 Sankyuk Dong Puk-ku, Daegu 702-701, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Food and Nutritional Genomics Research, Kyungpook National University, 1370 Sankyuk Dong Puk-ku, Daegu 702-701, Korea","institution_ids":["https://openalex.org/I31419693"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031004025","display_name":"Myung\u2010Sook Choi","orcid":"https://orcid.org/0000-0002-6399-6787","observed_orcids":["https://orcid.org/0000-0002-6399-6787"]},"institutions":[{"id":"https://openalex.org/I31419693","display_name":"Kyungpook National University","ror":"https://ror.org/040c17130","country_code":"KR","type":"education","lineage":["https://openalex.org/I31419693"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Myung-Sook Choi","raw_affiliation_strings":["Center for Food and Nutritional Genomics Research, Kyungpook National University,  1370 Sankyuk Dong Puk-ku, Daegu 702-701, Korea","Center for Food and Nutritional Genomics Research, Kyungpook National University, 1370 Sankyuk Dong Puk-ku, Daegu 702-701, Korea. mschoi@knu.ac.kr"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Food and Nutritional Genomics Research, Kyungpook National University,  1370 Sankyuk Dong Puk-ku, Daegu 702-701, Korea","institution_ids":["https://openalex.org/I31419693"]},{"raw_affiliation_string":"Center for Food and Nutritional Genomics Research, Kyungpook National University, 1370 Sankyuk Dong Puk-ku, Daegu 702-701, Korea. mschoi@knu.ac.kr","institution_ids":["https://openalex.org/I31419693"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5031004025"],"corresponding_institution_ids":["https://openalex.org/I31419693"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":16.0855,"has_fulltext":false,"cited_by_count":1964,"citation_normalized_percentile":{"value":0.99955615,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"15","issue":"4","first_page":"6184","last_page":"6223"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/adipokines","display_name":"adipokines","score":0.9950000047683716},{"id":"https://openalex.org/keywords/adipose-tissue-endocrine-function","display_name":"adipose tissue endocrine function","score":0.8379999995231628},{"id":"https://openalex.org/keywords/chronic-low-grade-inflammation","display_name":"low-grade inflammation","score":0.8629999756813049},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":1.0},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.8799999952316284},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":1.0},{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/metabolic-complications","display_name":"metabolic complications","score":0.5109999775886536},{"id":"https://openalex.org/keywords/adipose-tissue-dysfunction","display_name":"adipose tissue dysfunction","score":0.8640000224113464}],"concepts":[{"id":"https://openalex.org/C194832188","wikidata":"https://www.wikidata.org/wiki/Q2638593","display_name":"Adipokine","level":4,"score":0.9421831369400024},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.7972707152366638},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.7775760889053345},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.7112283706665039},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6217201352119446},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6205183267593384},{"id":"https://openalex.org/C2776954865","wikidata":"https://www.wikidata.org/wiki/Q1546498","display_name":"Nonalcoholic fatty liver disease","level":4,"score":0.5954188108444214},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.5495105385780334},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5267345905303955},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.47322145104408264},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.4690060317516327},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.447104275226593},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.43909990787506104},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.36323320865631104},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34282374382019043},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.24418959021568298}],"mesh":[{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D054392","descriptor_name":"Adipokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.3390/ijms15046184","doi":"https://doi.org/10.3390/ijms15046184","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms15046184","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2991963","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC4013623","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4013623","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4013623","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Mol Sci","raw_type":"Text"},{"id":"pmid:24733068","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24733068","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.651.8925","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.651.8925","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.mdpi.com/1422-0067/15/4/6184/pdf/","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:c9a28b2c74ed4131afe9b811603ef307","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c9a28b2c74ed4131afe9b811603ef307","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Molecular Sciences, Vol 15, Iss 4, Pp 6184-6223 (2014)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/ijms15046184","doi":"https://doi.org/10.3390/ijms15046184","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms15046184","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":284,"referenced_works":["https://openalex.org/W21995488","https://openalex.org/W57946966","https://openalex.org/W262298330","https://openalex.org/W1505211334","https://openalex.org/W1524321743","https://openalex.org/W1590709474","https://openalex.org/W1608606552","https://openalex.org/W1631449371","https://openalex.org/W1659985814","https://openalex.org/W1764140709","https://openalex.org/W1902862013","https://openalex.org/W1963533127","https://openalex.org/W1965296835","https://openalex.org/W1967130085","https://openalex.org/W1967161323","https://openalex.org/W1967466043","https://openalex.org/W1967972402","https://openalex.org/W1968580611","https://openalex.org/W1969070167","https://openalex.org/W1970065259","https://openalex.org/W1970971762","https://openalex.org/W1971401877","https://openalex.org/W1972896214","https://openalex.org/W1973573989","https://openalex.org/W1974599416","https://openalex.org/W1975015881","https://openalex.org/W1979030077","https://openalex.org/W1979651550","https://openalex.org/W1981261500","https://openalex.org/W1981484027","https://openalex.org/W1982168327","https://openalex.org/W1982484787","https://openalex.org/W1982584622","https://openalex.org/W1983017225","https://openalex.org/W1983844880","https://openalex.org/W1984672568","https://openalex.org/W1985399572","https://openalex.org/W1985592156","https://openalex.org/W1985774463","https://openalex.org/W1986499063","https://openalex.org/W1988826453","https://openalex.org/W1989020172","https://openalex.org/W1989535259","https://openalex.org/W1990311612","https://openalex.org/W1990370103","https://openalex.org/W1990955172","https://openalex.org/W1993203791","https://openalex.org/W1993514813","https://openalex.org/W1993959456","https://openalex.org/W1994784822","https://openalex.org/W1995000970","https://openalex.org/W1995079052","https://openalex.org/W1997757017","https://openalex.org/W2000054481","https://openalex.org/W2000054651","https://openalex.org/W2000276775","https://openalex.org/W2002811789","https://openalex.org/W2006142154","https://openalex.org/W2006433855","https://openalex.org/W2007405015","https://openalex.org/W2008869160","https://openalex.org/W2009013500","https://openalex.org/W2010245357","https://openalex.org/W2010895111","https://openalex.org/W2011020293","https://openalex.org/W2011473843","https://openalex.org/W2011859476","https://openalex.org/W2012753495","https://openalex.org/W2013358584","https://openalex.org/W2015768468","https://openalex.org/W2015925877","https://openalex.org/W2016675477","https://openalex.org/W2018135697","https://openalex.org/W2018165940","https://openalex.org/W2018393394","https://openalex.org/W2020841064","https://openalex.org/W2021525060","https://openalex.org/W2022531055","https://openalex.org/W2024661492","https://openalex.org/W2025479099","https://openalex.org/W2025596599","https://openalex.org/W2027391841","https://openalex.org/W2028395411","https://openalex.org/W2028441056","https://openalex.org/W2028987105","https://openalex.org/W2030585847","https://openalex.org/W2033124959","https://openalex.org/W2033202922","https://openalex.org/W2034151865","https://openalex.org/W2034541077","https://openalex.org/W2035994732","https://openalex.org/W2036689136","https://openalex.org/W2037720187","https://openalex.org/W2039432238","https://openalex.org/W2039486449","https://openalex.org/W2040109162","https://openalex.org/W2040479548","https://openalex.org/W2040863335","https://openalex.org/W2040874495","https://openalex.org/W2040901874","https://openalex.org/W2041830601","https://openalex.org/W2042444876","https://openalex.org/W2042706232","https://openalex.org/W2042742088","https://openalex.org/W2045913350","https://openalex.org/W2046208657","https://openalex.org/W2047189101","https://openalex.org/W2047442471","https://openalex.org/W2048034841","https://openalex.org/W2048619296","https://openalex.org/W2049342816","https://openalex.org/W2049965571","https://openalex.org/W2049988592","https://openalex.org/W2050330440","https://openalex.org/W2051051060","https://openalex.org/W2051227936","https://openalex.org/W2051958993","https://openalex.org/W2052180866","https://openalex.org/W2052227721","https://openalex.org/W2055844905","https://openalex.org/W2056092515","https://openalex.org/W2056568186","https://openalex.org/W2056728315","https://openalex.org/W2056767166","https://openalex.org/W2058410894","https://openalex.org/W2058461923","https://openalex.org/W2059652342","https://openalex.org/W2061278204","https://openalex.org/W2061320466","https://openalex.org/W2061819459","https://openalex.org/W2061918572","https://openalex.org/W2063271924","https://openalex.org/W2064968890","https://openalex.org/W2067096633","https://openalex.org/W2067359474","https://openalex.org/W2067757391","https://openalex.org/W2069492997","https://openalex.org/W2069936148","https://openalex.org/W2072174006","https://openalex.org/W2073293954","https://openalex.org/W2073643647","https://openalex.org/W2073656642","https://openalex.org/W2075592456","https://openalex.org/W2076094824","https://openalex.org/W2076310317","https://openalex.org/W2078355311","https://openalex.org/W2079102359","https://openalex.org/W2081455569","https://openalex.org/W2082269190","https://openalex.org/W2086682722","https://openalex.org/W2088940658","https://openalex.org/W2089514748","https://openalex.org/W2090289803","https://openalex.org/W2091484157","https://openalex.org/W2091536410","https://openalex.org/W2092136583","https://openalex.org/W2093545277","https://openalex.org/W2093711908","https://openalex.org/W2094747998","https://openalex.org/W2096299662","https://openalex.org/W2096421177","https://openalex.org/W2096574031","https://openalex.org/W2097055679","https://openalex.org/W2100198908","https://openalex.org/W2101333957","https://openalex.org/W2102009612","https://openalex.org/W2103416613","https://openalex.org/W2104084470","https://openalex.org/W2104711211","https://openalex.org/W2105448220","https://openalex.org/W2105641300","https://openalex.org/W2107550410","https://openalex.org/W2107592729","https://openalex.org/W2108096976","https://openalex.org/W2109384991","https://openalex.org/W2110500106","https://openalex.org/W2110678596","https://openalex.org/W2111200491","https://openalex.org/W2111784334","https://openalex.org/W2111842746","https://openalex.org/W2112377527","https://openalex.org/W2112914472","https://openalex.org/W2115817762","https://openalex.org/W2116404316","https://openalex.org/W2116994956","https://openalex.org/W2117361576","https://openalex.org/W2117537998","https://openalex.org/W2118166675","https://openalex.org/W2119171992","https://openalex.org/W2119411112","https://openalex.org/W2120590109","https://openalex.org/W2121492052","https://openalex.org/W2121517600","https://openalex.org/W2122484262","https://openalex.org/W2123216266","https://openalex.org/W2123544250","https://openalex.org/W2123627338","https://openalex.org/W2123706364","https://openalex.org/W2123820248","https://openalex.org/W2123824588","https://openalex.org/W2123960592","https://openalex.org/W2127509487","https://openalex.org/W2127738100","https://openalex.org/W2129316761","https://openalex.org/W2129785124","https://openalex.org/W2129973062","https://openalex.org/W2132197535","https://openalex.org/W2133425349","https://openalex.org/W2133846768","https://openalex.org/W2133966719","https://openalex.org/W2134133526","https://openalex.org/W2135110328","https://openalex.org/W2135642402","https://openalex.org/W2136024338","https://openalex.org/W2136795008","https://openalex.org/W2138489649","https://openalex.org/W2138750223","https://openalex.org/W2139351004","https://openalex.org/W2139613376","https://openalex.org/W2139833921","https://openalex.org/W2141550792","https://openalex.org/W2142394429","https://openalex.org/W2143164727","https://openalex.org/W2144032315","https://openalex.org/W2144126526","https://openalex.org/W2144144716","https://openalex.org/W2144178804","https://openalex.org/W2145690342","https://openalex.org/W2145697808","https://openalex.org/W2145725957","https://openalex.org/W2145805916","https://openalex.org/W2146845495","https://openalex.org/W2147053026","https://openalex.org/W2147554487","https://openalex.org/W2148378054","https://openalex.org/W2148379763","https://openalex.org/W2148722507","https://openalex.org/W2149613768","https://openalex.org/W2150232019","https://openalex.org/W2151476030","https://openalex.org/W2151605383","https://openalex.org/W2152688545","https://openalex.org/W2152788276","https://openalex.org/W2153071631","https://openalex.org/W2153651314","https://openalex.org/W2154442601","https://openalex.org/W2154993634","https://openalex.org/W2155518126","https://openalex.org/W2155867477","https://openalex.org/W2156280702","https://openalex.org/W2157559566","https://openalex.org/W2159346623","https://openalex.org/W2160412430","https://openalex.org/W2160490100","https://openalex.org/W2160930691","https://openalex.org/W2161327673","https://openalex.org/W2161508172","https://openalex.org/W2162107224","https://openalex.org/W2162572860","https://openalex.org/W2162746476","https://openalex.org/W2163567669","https://openalex.org/W2164012871","https://openalex.org/W2164476527","https://openalex.org/W2165202791","https://openalex.org/W2165604976","https://openalex.org/W2166193349","https://openalex.org/W2167370342","https://openalex.org/W2167634393","https://openalex.org/W2168140013","https://openalex.org/W2168647804","https://openalex.org/W2169055011","https://openalex.org/W2170582496","https://openalex.org/W2171882096","https://openalex.org/W2172055040","https://openalex.org/W2177671852","https://openalex.org/W2185551004","https://openalex.org/W2334309509","https://openalex.org/W2334337188","https://openalex.org/W2342275484","https://openalex.org/W2470404765","https://openalex.org/W2475316864","https://openalex.org/W4250725029","https://openalex.org/W6602322818","https://openalex.org/W6630027147"],"related_works":["https://openalex.org/W7099241847","https://openalex.org/W2159748100","https://openalex.org/W2903878444","https://openalex.org/W4390444500","https://openalex.org/W3192813543","https://openalex.org/W1501390512","https://openalex.org/W4317040855","https://openalex.org/W2088940658","https://openalex.org/W4224211165","https://openalex.org/W3021427717"],"abstract_inverted_index":{"Accumulating":[0],"evidence":[1,162],"indicates":[2],"that":[3],"obesity":[4,151,175],"is":[5,50,182],"closely":[6],"associated":[7,149],"with":[8,97,150],"an":[9,31,42,71],"increased":[10],"risk":[11],"of":[12,45,59,61,76,82,100,117,134,146,169,174,194],"metabolic":[13,136,158,178,192],"diseases":[14],"such":[15],"as":[16,55,70,86],"insulin":[17],"resistance,":[18],"type":[19],"2":[20],"diabetes,":[21],"dyslipidemia":[22],"and":[23,36,95,125,152,176],"nonalcoholic":[24],"fatty":[25],"liver":[26],"disease.":[27],"Obesity":[28],"results":[29],"from":[30,65],"imbalance":[32],"between":[33],"food":[34,66],"intake":[35,67],"energy":[37,63],"expenditure,":[38],"which":[39,90],"leads":[40],"to":[41,131,185],"excessive":[43],"accumulation":[44],"adipose":[46,77,123,126],"tissue.":[47],"Adipose":[48],"tissue":[49,78,124,127],"now":[51],"recognized":[52],"not":[53],"only":[54],"a":[56,80,98,195],"main":[57],"site":[58],"storage":[60],"excess":[62,122],"derived":[64],"but":[68],"also":[69],"endocrine":[72],"organ.":[73],"The":[74],"expansion":[75],"produces":[79],"number":[81],"bioactive":[83],"substances,":[84],"known":[85],"adipocytokines":[87],"or":[88,115],"adipokines,":[89],"trigger":[91],"chronic":[92],"low-grade":[93],"inflammation":[94],"interact":[96],"range":[99],"processes":[101],"in":[102,171],"many":[103],"different":[104],"organs.":[105],"Although":[106],"the":[107,132,144,153,167,172,188,191],"precise":[108],"mechanisms":[109,189],"are":[110],"still":[111,183],"unclear,":[112],"dysregulated":[113],"production":[114],"secretion":[116],"these":[118],"adipokines":[119,148,170],"caused":[120],"by":[121],"dysfunction":[128],"can":[129],"contribute":[130],"development":[133,173],"obesity-related":[135,157],"diseases.":[137,159],"In":[138],"this":[139],"review,":[140],"we":[141],"focus":[142],"on":[143,156],"role":[145],"several":[147],"potential":[154],"impact":[155],"Multiple":[160],"lines":[161],"provides":[163],"valuable":[164],"insights":[165],"into":[166],"roles":[168],"its":[177],"complications.":[179],"Further":[180],"research":[181],"required":[184],"fully":[186],"understand":[187],"underlying":[190],"actions":[193],"few":[196],"newly":[197],"identified":[198],"adipokines.":[199]},"counts_by_year":[{"year":2026,"cited_by_count":89},{"year":2025,"cited_by_count":140},{"year":2024,"cited_by_count":160},{"year":2023,"cited_by_count":183},{"year":2022,"cited_by_count":179},{"year":2021,"cited_by_count":187},{"year":2020,"cited_by_count":229},{"year":2019,"cited_by_count":204},{"year":2018,"cited_by_count":217},{"year":2017,"cited_by_count":187},{"year":2016,"cited_by_count":115},{"year":2015,"cited_by_count":54},{"year":2014,"cited_by_count":16}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}