{"id":"https://openalex.org/W1978768368","doi":"https://doi.org/10.1016/j.jss.2005.11.299","title":"Therapeutic angiogenesis in critical limb ischemia via the localized delivery of bFGF from ionic hydrogels","display_name":"Therapeutic angiogenesis in critical limb ischemia via the localized delivery of bFGF from ionic hydrogels","publication_year":2006,"publication_date":"2006-01-27","ids":{"openalex":"https://openalex.org/W1978768368","doi":"https://doi.org/10.1016/j.jss.2005.11.299","mag":"1978768368"},"language":"en","primary_location":{"id":"doi:10.1016/j.jss.2005.11.299","doi":"https://doi.org/10.1016/j.jss.2005.11.299","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jss.2005.11.299","pdf_url":null,"source":{"id":"https://openalex.org/S45161156","display_name":"Journal of Surgical Research","issn_l":"0022-4804","issn":["0022-4804","1095-8673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042411252","display_name":"Hans Layman","orcid":"https://orcid.org/0000-0003-4480-5153","observed_orcids":["https://orcid.org/0000-0003-4480-5153"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Layman","raw_affiliation_strings":["University of Miami"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Miami","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013374482","display_name":"S. Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Li","raw_affiliation_strings":["University of Miami"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Miami","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034119339","display_name":"Si M. Pham","orcid":"https://orcid.org/0000-0001-7396-8344","observed_orcids":["https://orcid.org/0000-0001-7396-8344"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S.M. Pham","raw_affiliation_strings":["University of Miami"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Miami","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051623365","display_name":"Fotios M. Andreopoulos","orcid":"https://orcid.org/0000-0003-4931-8354","observed_orcids":["https://orcid.org/0000-0003-4931-8354"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F.M. Andreopoulos","raw_affiliation_strings":["University of Miami"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Miami","institution_ids":["https://openalex.org/I145608581"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I145608581"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":0.1713,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.53811563,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"130","issue":"2","first_page":"265","last_page":"266"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.016200000420212746,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.012199999764561653,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/therapeutic-angiogenesis","display_name":"therapeutic angiogenesis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/critical-limb-ischemia","display_name":"critical limb ischemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/basic-fibroblast-growth-factor","display_name":"basic fibroblast growth factor","score":0.9079999923706055},{"id":"https://openalex.org/keywords/ionic-hydrogels","display_name":"ionic hydrogels","score":0.9430000185966492},{"id":"https://openalex.org/keywords/gelatin-scaffolds","display_name":"gelatin scaffolds","score":0.8989999890327454},{"id":"https://openalex.org/keywords/poly-l-glutamic-acid","display_name":"poly(L-glutamic acid)","score":0.8610000014305115},{"id":"https://openalex.org/keywords/poly-l-lysine","display_name":"poly-L-lysine","score":0.9879999756813049},{"id":"https://openalex.org/keywords/controlled-drug-delivery","display_name":"controlled drug delivery","score":0.6949999928474426},{"id":"https://openalex.org/keywords/peripheral-arterial-disease","display_name":"peripheral arterial disease","score":0.8830000162124634},{"id":"https://openalex.org/keywords/hindlimb-ischemia","display_name":"hindlimb ischemia","score":0.9440000057220459},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.5659999847412109},{"id":"https://openalex.org/keywords/hydrogel-swelling","display_name":"hydrogel swelling","score":0.6980000138282776},{"id":"https://openalex.org/keywords/laser-doppler-imaging","display_name":"laser Doppler imaging","score":0.8149999976158142},{"id":"https://openalex.org/keywords/covalent-cross-linking","display_name":"covalent cross-linking","score":0.7490000128746033},{"id":"https://openalex.org/keywords/femoral-artery-ligation","display_name":"femoral artery ligation","score":0.6460000276565552}],"concepts":[{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.8212391138076782},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.7143634557723999},{"id":"https://openalex.org/C2778823387","wikidata":"https://www.wikidata.org/wiki/Q179254","display_name":"Gelatin","level":2,"score":0.6841696500778198},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6337352991104126},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5667900443077087},{"id":"https://openalex.org/C2781188250","wikidata":"https://www.wikidata.org/wiki/Q4455440","display_name":"Therapeutic angiogenesis","level":4,"score":0.5270711779594421},{"id":"https://openalex.org/C2777587049","wikidata":"https://www.wikidata.org/wiki/Q20969945","display_name":"Basic fibroblast growth factor","level":4,"score":0.5164673328399658},{"id":"https://openalex.org/C2778271429","wikidata":"https://www.wikidata.org/wiki/Q1281049","display_name":"Neovascularization","level":3,"score":0.4957183599472046},{"id":"https://openalex.org/C2778540859","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Swelling","level":2,"score":0.46959128975868225},{"id":"https://openalex.org/C179437574","wikidata":"https://www.wikidata.org/wiki/Q15089798","display_name":"Ligation","level":2,"score":0.450031042098999},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.4347624182701111},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.34427034854888916},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28449350595474243},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.24606472253799438},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.20278584957122803},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18136003613471985},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1681084930896759},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.15498560667037964},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.144517719745636},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.09646126627922058},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08713194727897644}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jss.2005.11.299","doi":"https://doi.org/10.1016/j.jss.2005.11.299","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jss.2005.11.299","pdf_url":null,"source":{"id":"https://openalex.org/S45161156","display_name":"Journal of Surgical Research","issn_l":"0022-4804","issn":["0022-4804","1095-8673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/6","score":0.5,"display_name":"Clean water and sanitation"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1994786603","https://openalex.org/W2026616377","https://openalex.org/W2075790920","https://openalex.org/W2047751927","https://openalex.org/W2100292649","https://openalex.org/W3102439670","https://openalex.org/W2063446635","https://openalex.org/W1991816748","https://openalex.org/W7098844978","https://openalex.org/W2128931336"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}