{"id":"https://openalex.org/W1978752676","doi":"https://doi.org/10.1002/jcp.1041230313","title":"Enterocytic differentiation and glucose utilization in the human colon tumor cell line Caco\u20102: Modulation by forskolin","display_name":"Enterocytic differentiation and glucose utilization in the human colon tumor cell line Caco\u20102: Modulation by forskolin","publication_year":1985,"publication_date":"1985-06-01","ids":{"openalex":"https://openalex.org/W1978752676","doi":"https://doi.org/10.1002/jcp.1041230313","mag":"1978752676","pmid":"https://pubmed.ncbi.nlm.nih.gov/2985631"},"language":"en","primary_location":{"id":"doi:10.1002/jcp.1041230313","doi":"https://doi.org/10.1002/jcp.1041230313","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jcp.1041230313","pdf_url":null,"source":{"id":"https://openalex.org/S43643205","display_name":"Journal of Cellular Physiology","issn_l":"0021-9541","issn":["0021-9541","1097-4652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108381660","display_name":"Monique Rousset","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210166329","display_name":"H\u00f4pital Broussais","ror":"https://ror.org/05h8pvh61","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166329"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Monique Rousset","raw_affiliation_strings":["Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]},{"raw_affiliation_string":"Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076634867","display_name":"Marc Laburthe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marc Laburthe","raw_affiliation_strings":["Unite\u0301 de Recherches de Diabe\u0301tologie et d'E\u0301tudes Radio-Immunologiques des Hormones Prote\u0301iques, INSERM U55, Ho\u0302pital Saint-Antoine, 75012 Paris, France","Unit\u00e9 de Recherches de Diab\u00e9tologie et d'\u00c9tudes Radio-Immunologiques des Hormones Prot\u00e9iques, INSERM U55, H\u00f4pital Saint-Antoine, 75012 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unite\u0301 de Recherches de Diabe\u0301tologie et d'E\u0301tudes Radio-Immunologiques des Hormones Prote\u0301iques, INSERM U55, Ho\u0302pital Saint-Antoine, 75012 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928"]},{"raw_affiliation_string":"Unit\u00e9 de Recherches de Diab\u00e9tologie et d'\u00c9tudes Radio-Immunologiques des Hormones Prot\u00e9iques, INSERM U55, H\u00f4pital Saint-Antoine, 75012 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103530922","display_name":"Mo\u0131\u0308se Pinto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210166329","display_name":"H\u00f4pital Broussais","ror":"https://ror.org/05h8pvh61","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166329"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mo\u00efse Pinto","raw_affiliation_strings":["Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]},{"raw_affiliation_string":"Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113687008","display_name":"Guillemette Chevalier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210166329","display_name":"H\u00f4pital Broussais","ror":"https://ror.org/05h8pvh61","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166329"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Guillemette Chevalier","raw_affiliation_strings":["Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]},{"raw_affiliation_string":"Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074672318","display_name":"Christiane Rouyer\u2010Fessard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christiane Rouyer\u2010Fessard","raw_affiliation_strings":["Unite\u0301 de Recherches de Diabe\u0301tologie et d'E\u0301tudes Radio-Immunologiques des Hormones Prote\u0301iques, INSERM U55, Ho\u0302pital Saint-Antoine, 75012 Paris, France","Unit\u00e9 de Recherches de Diab\u00e9tologie et d'\u00c9tudes Radio-Immunologiques des Hormones Prot\u00e9iques, INSERM U55, H\u00f4pital Saint-Antoine, 75012 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unite\u0301 de Recherches de Diabe\u0301tologie et d'E\u0301tudes Radio-Immunologiques des Hormones Prote\u0301iques, INSERM U55, Ho\u0302pital Saint-Antoine, 75012 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928"]},{"raw_affiliation_string":"Unit\u00e9 de Recherches de Diab\u00e9tologie et d'\u00c9tudes Radio-Immunologiques des Hormones Prot\u00e9iques, INSERM U55, H\u00f4pital Saint-Antoine, 75012 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113683951","display_name":"Elisabeth Dussaulx","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210166329","display_name":"H\u00f4pital Broussais","ror":"https://ror.org/05h8pvh61","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166329"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Elisabeth Dussaulx","raw_affiliation_strings":["Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]},{"raw_affiliation_string":"Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108094797","display_name":"Germain Trugnan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210166329","display_name":"H\u00f4pital Broussais","ror":"https://ror.org/05h8pvh61","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166329"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Germain Trugnan","raw_affiliation_strings":["Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]},{"raw_affiliation_string":"Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077926718","display_name":"Nathalie Boige","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nathalie Boige","raw_affiliation_strings":["Unite\u0301 de Recherches de Diabe\u0301tologie et d'E\u0301tudes Radio-Immunologiques des Hormones Prote\u0301iques, INSERM U55, Ho\u0302pital Saint-Antoine, 75012 Paris, France","Unit\u00e9 de Recherches de Diab\u00e9tologie et d'\u00c9tudes Radio-Immunologiques des Hormones Prot\u00e9iques, INSERM U55, H\u00f4pital Saint-Antoine, 75012 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unite\u0301 de Recherches de Diabe\u0301tologie et d'E\u0301tudes Radio-Immunologiques des Hormones Prote\u0301iques, INSERM U55, Ho\u0302pital Saint-Antoine, 75012 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928"]},{"raw_affiliation_string":"Unit\u00e9 de Recherches de Diab\u00e9tologie et d'\u00c9tudes Radio-Immunologiques des Hormones Prot\u00e9iques, INSERM U55, H\u00f4pital Saint-Antoine, 75012 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111598252","display_name":"J.-F. Brun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210166329","display_name":"H\u00f4pital Broussais","ror":"https://ror.org/05h8pvh61","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166329"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean\u2010Louis Brun","raw_affiliation_strings":["Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]},{"raw_affiliation_string":"Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003217193","display_name":"Alain Zweibaum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210166329","display_name":"H\u00f4pital Broussais","ror":"https://ror.org/05h8pvh61","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166329"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Alain Zweibaum","raw_affiliation_strings":["Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unite\u0301 de Recherches sur le Me\u0301tabolisme et la Diffe\u0301renciation de Cellules en Culture, INSERM U178, Ho\u0302pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]},{"raw_affiliation_string":"Unit\u00e9 de Recherches sur le M\u00e9tabolisme et la Diff\u00e9renciation de Cellules en Culture, INSERM U178, H\u00f4pital Broussais, 75014 Paris","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5108381660"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210166329"],"apc_list":{"value":5230,"currency":"USD","value_usd":5230},"apc_paid":null,"fwci":4.2629,"has_fulltext":false,"cited_by_count":151,"citation_normalized_percentile":{"value":0.94778857,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"123","issue":"3","first_page":"377","last_page":"385"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13199","display_name":"Digestive system and related health","score":0.47749999165534973,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13199","display_name":"Digestive system and related health","score":0.47749999165534973,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.3522999882698059,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.05559999868273735,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/forskolin","display_name":"forskolin","score":0.8019999861717224},{"id":"https://openalex.org/keywords/caco-2-cells","display_name":"Caco-2 cells","score":0.925000011920929},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.5180000066757202},{"id":"https://openalex.org/keywords/glycogenolysis","display_name":"glycogenolysis","score":0.7829999923706055},{"id":"https://openalex.org/keywords/glucose-utilization","display_name":"glucose utilization","score":0.652999997138977},{"id":"https://openalex.org/keywords/camp-accumulation","display_name":"cAMP accumulation","score":0.8199999928474426},{"id":"https://openalex.org/keywords/adenylate-cyclase","display_name":"adenylate cyclase","score":0.8939999938011169},{"id":"https://openalex.org/keywords/brush-border-enzymes","display_name":"brush border enzymes","score":0.8799999952316284},{"id":"https://openalex.org/keywords/sucrase","display_name":"sucrase","score":0.972000002861023},{"id":"https://openalex.org/keywords/cd13","display_name":"CD13","score":0.9419999718666077},{"id":"https://openalex.org/keywords/alkaline-phosphatase","display_name":"alkaline phosphatase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cell-confluency","display_name":"cell confluence","score":0.6549999713897705}],"concepts":[{"id":"https://openalex.org/C2779276759","wikidata":"https://www.wikidata.org/wiki/Q412747","display_name":"Forskolin","level":3,"score":0.8413569927215576},{"id":"https://openalex.org/C5426402","wikidata":"https://www.wikidata.org/wiki/Q2462753","display_name":"Brush border","level":4,"score":0.6167066097259521},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.524949312210083},{"id":"https://openalex.org/C2777499176","wikidata":"https://www.wikidata.org/wiki/Q174936","display_name":"Glycogen","level":2,"score":0.4724714457988739},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4315774142742157},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4301859140396118},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4223666787147522},{"id":"https://openalex.org/C193176779","wikidata":"https://www.wikidata.org/wiki/Q5016050","display_name":"Caco-2","level":3,"score":0.41375795006752014},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.35623034834861755},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.3492160439491272},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2402871549129486},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.06004214286804199},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004224","descriptor_name":"Diterpenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005576","descriptor_name":"Colforsin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006003","descriptor_name":"Glycogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006867","descriptor_name":"Hydrolases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007773","descriptor_name":"Lactates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008871","descriptor_name":"Microvilli","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/jcp.1041230313","doi":"https://doi.org/10.1002/jcp.1041230313","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jcp.1041230313","pdf_url":null,"source":{"id":"https://openalex.org/S43643205","display_name":"Journal of Cellular Physiology","issn_l":"0021-9541","issn":["0021-9541","1097-4652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Physiology","raw_type":"journal-article"},{"id":"pmid:2985631","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2985631","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cellular physiology","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-00814012v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-00814012","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Cellular Physiology, 1985, 123 ((3)), pp.377-85. ⟨10.1002/jcp.1041230313⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1504098071","https://openalex.org/W1507420703","https://openalex.org/W1524699587","https://openalex.org/W1535668052","https://openalex.org/W1693678674","https://openalex.org/W1775749144","https://openalex.org/W1874268348","https://openalex.org/W1963958199","https://openalex.org/W1980262453","https://openalex.org/W2001992996","https://openalex.org/W2009291798","https://openalex.org/W2009708970","https://openalex.org/W2012345358","https://openalex.org/W2021475662","https://openalex.org/W2029890054","https://openalex.org/W2030834479","https://openalex.org/W2042871417","https://openalex.org/W2054707772","https://openalex.org/W2059582189","https://openalex.org/W2061689370","https://openalex.org/W2063367991","https://openalex.org/W2063738348","https://openalex.org/W2065607376","https://openalex.org/W2123929920","https://openalex.org/W2130508879","https://openalex.org/W2182432763","https://openalex.org/W2206402902","https://openalex.org/W2404082640","https://openalex.org/W2409411326","https://openalex.org/W2413595556","https://openalex.org/W3023773984","https://openalex.org/W3209951468"],"related_works":["https://openalex.org/W1968536031","https://openalex.org/W2368456829","https://openalex.org/W2338119267","https://openalex.org/W2129724870","https://openalex.org/W2402749343","https://openalex.org/W7134431044","https://openalex.org/W7134332082","https://openalex.org/W2138925572","https://openalex.org/W1885267328","https://openalex.org/W1994851582"],"abstract_inverted_index":{"The":[0,19,106,139],"human":[1],"colon":[2],"cancer":[3],"line":[4],"Caco-2":[5,61],"exhibits":[6],"after":[7,97,104],"confluency":[8],"a":[9,37,112,127,178,268],"concomitant":[10],"increase":[11,194,216,273],"of":[12,21,32,49,53,66,108,115,135,141,165,171,181,184,191,195,197,213,217,219,227,242,262,265,271],"glycogen":[13,130,280],"accumulation":[14,117],"and":[15,125,147,153,169,176,201,239,277],"an":[16,30,64,189,211,255],"enterocytic":[17],"differentiation.":[18],"purpose":[20],"this":[22],"work":[23],"was":[24,95,102],"to":[25,119],"investigate":[26],"whether":[27,43],"forskolin":[28],"(FK),":[29],"activator":[31],"adenylate":[33,58],"cyclase,":[34],"would":[35,45],"induce":[36],"permanent":[38,113],"glycogenolysis":[39],"and,":[40],"if":[41],"so,":[42],"it":[44],"result":[46],"in":[47,60,88,111,126,150,204,221,231,246,274,279],"modifications":[48,238],"the":[50,54,80,86,93,100,122,136,166,172,182,192,205,214,222,228,236,240,243,247,260,263,272],"differentiation":[51,264],"pattern":[52],"cells.":[55],"FK":[56,75,109],"activates":[57],"cyclase":[59],"cells":[62,81],"with":[63,74,161,177,254],"ED50":[65],"7":[67],"X":[68],"10(-6)M.":[69],"Three":[70],"different":[71],"treatment":[72,94,101],"protocols":[73,151],"(10(-5)M)":[76],"were":[77,82],"applied:":[78],"1)":[79],"treated":[83],"during":[84],"all":[85],"time":[87],"culture":[89],"(20":[90],"days);":[91],"2)":[92],"started":[96],"confluency;":[98],"3)":[99],"interrupted":[103],"confluency.":[105],"presence":[107],"results":[110,229],"stimulation":[114],"cAMP":[116,257],"(10":[118],"20":[120],"fold":[121,149],"basal":[123],"values)":[124],"permanently":[128],"reduced":[129],"content":[131],"(30":[132],"or":[133],"50%":[134],"control":[137],"values).":[138],"rates":[140],"glucose":[142,275],"consumption":[143,276],"are":[144,159,251],"increased":[145,256],"three":[146],"five":[148],"1":[152],"3":[154],"respectively.":[155],"These":[156],"metabolic":[157],"changes":[158,163],"associated":[160,253],"morphological":[162,237],"(tightening":[164],"intercellular":[167],"spaces":[168],"shortening":[170],"brush":[173,185,206,248],"border":[174,186,207,249],"microvilli)":[175],"dual":[179],"inhibition":[180,190,212,261],"activities":[183,245],"hydrolases:":[187],"a)":[188],"post-confluent":[193,215],"activity":[196,218],"sucrase,":[198],"aminopeptidase":[199],"N":[200],"alkaline":[202],"phosphatase":[203],"enriched":[208],"fraction;":[209],"b)":[210],"sucrase":[220,266],"cell":[223],"homogenate.":[224],"A":[225],"comparison":[226],"obtained":[230],"each":[232],"protocol":[233],"shows":[234],"that":[235],"decrease":[241,278],"enzyme":[244],"fraction":[250],"regularly":[252],"accumulation,":[258],"whereas":[259],"is":[267],"direct":[269],"consequence":[270],"stores.":[281]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}