{"id":"https://openalex.org/W1978675114","doi":"https://doi.org/10.3892/ijo.8.3.543","title":"Antibody-dependent cytotoxic activity on human cancer cells expressing UK 114 tumor membrane antigen","display_name":"Antibody-dependent cytotoxic activity on human cancer cells expressing UK 114 tumor membrane antigen","publication_year":1996,"publication_date":"1996-03-01","ids":{"openalex":"https://openalex.org/W1978675114","doi":"https://doi.org/10.3892/ijo.8.3.543","mag":"1978675114","pmid":"https://pubmed.ncbi.nlm.nih.gov/21544394"},"language":"en","primary_location":{"id":"doi:10.3892/ijo.8.3.543","doi":"https://doi.org/10.3892/ijo.8.3.543","is_oa":false,"landing_page_url":"https://doi.org/10.3892/ijo.8.3.543","pdf_url":null,"source":{"id":"https://openalex.org/S4210208883","display_name":"International Journal of Oncology","issn_l":"1019-6439","issn":["1019-6439","1791-2423"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["dongbi-d","jufo-1","medline","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079938648","display_name":"Alberto Bartorelli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A Bartorelli","raw_affiliation_strings":["UNIV TURIN,DEPT BIOMED SCI & ONCOL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT NEPHROUROL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT BIOL & CLIN SCI,I-10126 TURIN,ITALY. UNIV MILAN,G SISINI INST,I-20138 MILAN,ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNIV TURIN,DEPT BIOMED SCI & ONCOL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT NEPHROUROL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT BIOL & CLIN SCI,I-10126 TURIN,ITALY. UNIV MILAN,G SISINI INST,I-20138 MILAN,ITALY","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077458481","display_name":"Benedetta Bussolati","orcid":"https://orcid.org/0000-0002-3663-5134","observed_orcids":["https://orcid.org/0000-0002-3663-5134"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"B Bussolati","raw_affiliation_strings":["UNIV TURIN,DEPT BIOMED SCI & ONCOL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT NEPHROUROL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT BIOL & CLIN SCI,I-10126 TURIN,ITALY. UNIV MILAN,G SISINI INST,I-20138 MILAN,ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNIV TURIN,DEPT BIOMED SCI & ONCOL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT NEPHROUROL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT BIOL & CLIN SCI,I-10126 TURIN,ITALY. UNIV MILAN,G SISINI INST,I-20138 MILAN,ITALY","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031222190","display_name":"Michele Millesimo","orcid":"https://orcid.org/0000-0002-7903-4873","observed_orcids":["https://orcid.org/0000-0002-7903-4873"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M Millesimo","raw_affiliation_strings":["UNIV TURIN,DEPT BIOMED SCI & ONCOL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT NEPHROUROL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT BIOL & CLIN SCI,I-10126 TURIN,ITALY. UNIV MILAN,G SISINI INST,I-20138 MILAN,ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNIV TURIN,DEPT BIOMED SCI & ONCOL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT NEPHROUROL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT BIOL & CLIN SCI,I-10126 TURIN,ITALY. UNIV MILAN,G SISINI INST,I-20138 MILAN,ITALY","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054916452","display_name":"Patrizia Gugliotta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"P Gugliotta","raw_affiliation_strings":["UNIV TURIN,DEPT BIOMED SCI & ONCOL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT NEPHROUROL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT BIOL & CLIN SCI,I-10126 TURIN,ITALY. UNIV MILAN,G SISINI INST,I-20138 MILAN,ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNIV TURIN,DEPT BIOMED SCI & ONCOL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT NEPHROUROL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT BIOL & CLIN SCI,I-10126 TURIN,ITALY. UNIV MILAN,G SISINI INST,I-20138 MILAN,ITALY","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I55143463"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111965604","display_name":"Gianni Bussolati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Bussolati","raw_affiliation_strings":["UNIV TURIN,DEPT BIOMED SCI & ONCOL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT NEPHROUROL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT BIOL & CLIN SCI,I-10126 TURIN,ITALY. UNIV MILAN,G SISINI INST,I-20138 MILAN,ITALY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNIV TURIN,DEPT BIOMED SCI & ONCOL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT NEPHROUROL,I-10126 TURIN,ITALY. UNIV TURIN,DEPT BIOL & CLIN SCI,I-10126 TURIN,ITALY. UNIV MILAN,G SISINI INST,I-20138 MILAN,ITALY","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I55143463"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1447,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.77872033,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"8","issue":"3","first_page":"543","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.010200000368058681,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antibody-dependent-cellular-cytotoxicity","display_name":"antibody-dependent cellular cytotoxicity","score":0.8930000066757202},{"id":"https://openalex.org/keywords/ht-29-cells","display_name":"HT-29 cells","score":0.7039999961853027},{"id":"https://openalex.org/keywords/xenograft-tumor-growth-inhibition","display_name":"xenograft tumor growth inhibition","score":0.8289999961853027}],"concepts":[{"id":"https://openalex.org/C73588182","wikidata":"https://www.wikidata.org/wiki/Q2663023","display_name":"Cytolysis","level":4,"score":0.8033915758132935},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6851085424423218},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6646125912666321},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.6527456641197205},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6293126344680786},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.5402770638465881},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.49830198287963867},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.4756878614425659},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4647039473056793},{"id":"https://openalex.org/C2781018059","wikidata":"https://www.wikidata.org/wiki/Q207609","display_name":"Oncogene","level":4,"score":0.4476293623447418},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.43118464946746826},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.42406678199768066},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.41469305753707886},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.3936542868614197},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3552762269973755},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29870229959487915},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15625321865081787},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3892/ijo.8.3.543","doi":"https://doi.org/10.3892/ijo.8.3.543","is_oa":false,"landing_page_url":"https://doi.org/10.3892/ijo.8.3.543","pdf_url":null,"source":{"id":"https://openalex.org/S4210208883","display_name":"International Journal of Oncology","issn_l":"1019-6439","issn":["1019-6439","1791-2423"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["dongbi-d","jufo-1","medline","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Oncology","raw_type":"journal-article"},{"id":"pmid:21544394","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21544394","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of oncology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2037947966","https://openalex.org/W1982443628","https://openalex.org/W1980846395","https://openalex.org/W1890163579","https://openalex.org/W1990352763","https://openalex.org/W2011895721","https://openalex.org/W2166904264","https://openalex.org/W2168275983","https://openalex.org/W2017928793","https://openalex.org/W2466982465"],"abstract_inverted_index":{"The":[0],"monoclonal":[1],"antibody":[2],"(P-3":[3],"mAb)":[4],"and":[5,44,90],"the":[6,29,83],"rabbit":[7],"immune":[8],"sera":[9],"(RIS)":[10],"recognizing":[11],"a":[12],"14":[13],"kDa":[14],"perchloric":[15],"acid":[16],"soluble":[17],"protein":[18],"extracted":[19],"from":[20],"goat":[21],"liver":[22],"(UK":[23],"114),":[24],"locate":[25],"this":[26],"antigen":[27],"on":[28],"cell":[30,36,84],"membrane":[31,85],"of":[32,69],"several":[33],"human":[34,77],"cancer":[35],"lines.":[37],"UK":[38,80],"114-positive":[39],"cells":[40],"(e.g.":[41],"HT":[42,58],"29":[43,59],"KATO":[45],"VI":[46],"cells)":[47],"undergo":[48,87],"antibody-dependent":[49],"cytolysis":[50,89],"bl":[51],"vitro.":[52],"In":[53],"nu/nu":[54],"mice":[55],"bearing":[56],"xenografted":[57],"cells,":[60],"tumor":[61],"growth":[62,91],"was":[63],"markedly":[64],"impaired":[65],"by":[66],"peri-tumoral":[67],"injection":[68],"anti-UK":[70],"114":[71,81],"antibodies.":[72],"These":[73],"experiments":[74],"suggest":[75],"that":[76],"tumors":[78],"expressing":[79],"over":[82],"may":[86],"antibody-mediated":[88],"control.":[92]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":2}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}